but would prevent the patient from rejecting the cells. With this scenario functional ovarian tissue from donors could be used to engineer bioartificial ovaries for women with non-functioning ovaries.
Lung cancer is the leading cause of cancer-related death among women worldwide with only one in seven patients surviving for five years after diagnosis. Emerging evidence suggests that female hormones particularly estrogens
In this analysis patients were divided into three groups according to soy food intake prior to lung cancer diagnosis. The highest and lowest intake levels were equivalent to approximately 4 oz or more and 2 oz or less tofu
Patients with the highest soy food intake had markedly better overall survival compared with those with the lowest intake 60 percent of patients in the highest intake group and 50 percent in the lowest intake group were alive
whether consumption of soy food after diagnosis of lung cancer affects survival particularly among patients with early-stage disease who may benefit most from a nutritional intervention.
for patients during and after radiation therapy and beyond. Radiation treatment of organs with cancer is designed to give enough of a dose to be toxic to the cancer tumor with minimal impact to the surrounding tissue
or the ability of the patients to think and perform tasks such as remembering a grocery list
and quality of life becomes a very important issue for these patients. More research is necessary to validate these data she said.
which might include a doctor advising a patient to lose weight and to exercise. In this study the enhanced UCC provided participants with two meetings with a registered dietitian and monthly newsletters.
A team led by Rice physicist Ching-Hwa Kiang found that shear forces like those found in small arteries of patients with atherosclerosis cause snippets of nonclotting VWF to change into a clot-forming shape for hours at a time.
which suggests the use of GSSE as a preventive nutriceutical for high-risk patients said co-author Kamel Charradi a researcher with the Laboratory of Bioactive Substance at the Center of Biotechnology of Borj-Cedria (CBBC) in Tunisia.
and produce intestinal cells suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).
The reason why that is so striking and important to us is had these patients no intention of quitting says addiction expert Jon Ebbert M d. a tobacco researcher at the Mayo Clinic Nicotine Dependence Center.
Ensor and Raun noted the patients died in more than 90 percent of the cases which occurred more during the hot summer months (55 percent of total cases).
#Researchers find potential new therapeutic target for treating non-small cell lung cancerresearchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer.
However patients eventually develop resistance to treatment. There is a great need to better understand the molecular mechanism of resistance
and vegetables to the diet may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build up according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).
This is particularly common in patients with CKD because the kidneys are responsible for removing acid through the urine.
Alkali supplementation therapy such as bicarbonate is used to treat CKD patients with severe metabolic acidosis but simply adding more fruits and vegetables
Nimrit Goraya MD Donald Wesson MD (Texas A&m College of Medicine) and their colleagues tested this by randomizing 71 patients with hypertensive stage 4 CKD to receive added fruits and vegetables
PTCO2 was higher in patients receiving bicarbonate than in those receiving added fruits and vegetables.#¢
and vegetables patients had a favorable response by reduction of urinary kidney injury markers said Dr. Wesson.
A small group of highly motivated patients wishing to reduce their pill burden through dietary modification may benefit from the results of this study.
However many patients find it difficult to follow a diet high in fruits and vegetables and might
and without dietary intervention in patients with chronic kidney disease is needed urgently. Study co-authors include Jan Simoni Phd and Chan-Hee Jo Phd.
In this research zinc's activity was studied in the context of sepsis a devastating systemic response to infection that is a common cause of death in intensive care-unit unit patients.
While this study and previous work linking zinc deficiency to inflammation might suggest that supplementation could help very sick ICU patients it's still too early to make that leap.
In a New zealand study ischemic stroke and transient ischemic attack (TIA) patients were 2. 3 times more likely to have cannabis also known as marijuana detected in urine tests as other age
and sex matched patients researchers said. This is the first case-controlled study to show a possible link to the increased risk of stroke from cannabis said P. Alan Barber Ph d. M d. study lead investigator and professor of clinical neurology at the University of Auckland
The study included 160 ischemic stroke/TIA patients 18-55 years old who had urine screens upon admission to the hospital.
Among the patients 150 had ischemic stroke and 10 had TIAS. Sixteen percent of patients had positive drug screens mostly male who also smoked tobacco.
Only 8. 1 percent of controls tested positive for cannabis in urine samples. Researchers found no differences in age stroke mechanism or most vascular risk factors between marijuana users and non-users.
These patients usually had no other vascular risk factors apart from tobacco alcohol and other drug usage.
and control patients about cannabis use is likely to obtain unreliable responses Barber said. In the study the regional ethics committee allowed researchers to use urine samples from other hospitalized patients.
But researchers knew only the age sex and ethnicity for matching due to a lack of consent.
because all but one of the stroke patients who were cannabis users also used tobacco regularly.
However the high prevalence of cannabis use in this cohort of younger stroke patients makes this research imperative.
in the body and the development of type 2 diabetes regardless of the patient's age gender or body mass index.
According to the National Institutes of Neurological disorders and Stroke (NINDS) roughly 20000 to 30000 Americans have known ALS#lso as Lou gehrig s disease#nd another 5000 patients are diagnosed annually with the disease.
Using outpatient electronic medical records the researchers identified whether the participants developed cardiovascular disease diabetes mellitus hypertension (high blood pressure) and metabolic syndrome during the five-year period.
and colleagues recruited 45 patients with early metabolic syndrome--defined as having at least three risk factors for metabolic syndrome including central obesity hypertension mild increases in glucose levels not yet in the diabetic range(<126 mg/dl
Some people view bariatric surgery as a quick fix for obesity but at Wake Forest Baptist more is expected of patients than just showing up for the procedure.
Patients are encouraged to lose weight or at least stay weight neutral in the month or so before undergoing bariatric surgery which reduces the size of the stomach or limits its capacity to process food.
By adopting new habits during this period most patients lose a significant amount of weight before the operation said Dr. Adolfo Fuzz Fernandez co-director of the Weight Management Center and head of its bariatric
In other words patients who have undergone bariatric surgery can put weight back on if they haven't changed their habits.
--and most of those patients do really well''Fernandez said. We don't see a lot of recidivism.
research findsnew research from Wake Forest Baptist Medical center shows that patients suffering from aggressive brain tumors can be treated effectively with smaller radiation fields to spare the rest of the brain and preserve cognition.
For patients with glioblastoma we now know we can safely and effectively treat them with smaller radiation fields to spare the rest of their normal brain said lead investigator Michael D. Chan M d. assistant professor of radiation oncology at Wake Forest Baptist.
Chan said that a patient's cognition is related to how much normal brain is irradiated so focusing radiation on smaller areas of the brain may help preserve cognition
Overall while long-term survival rates for glioblastoma multiforme patients have not improved by much with treatment advances the ability to treat with smaller radiation fields preserves cognition
While there have been other similar studies this one is the largest to compare smaller radiation margins to larger ones to document differences in patterns of failure for patients Chan said.
For this retrospective study records for 161 patients treated at Wake Forest Baptist over the last 10 years were reviewed.
so dementia has a significant impact not only on the patients but on their families and carers.
The new approach not yet tested in patients involves isolating cells from banked donor corneas to grow replacement corneal tissue in the lab. The advantage is that cells from a single donor could potentially benefit multiple patients with impaired vision.
and Drug Administration to begin studies in human patients. This is expected to take several years.
The current surgical technique is to replace a patient's damaged CECS with a very thin layer of tissue containing cells from a cadaveric donor cornea.
It is exciting that a collaboration based in the Piedmont Triad research Park right here in Winston-salem has the potential to create products that can bring benefits to patients throughout the world said Eric Tomlinson D. Sc.
how to retrieve the genome of a specific pathogen from a mixture of DNAS in a patient and its microbial cohabitants?
Statistics released last year show that more patients--like Aspen and her family--are turning to the University of Utah for liver transplant services.
In 2013 the University of Utah performed the most liver transplants in the state with 35 patients undergoing lifesaving procedures at the U. The U s liver transplant program's success isn't solely based on numbers however.
One example of the program's positive strides is a prestigious designation from the University Healthsystem Consortium for the outcomes of patients who've received a liver transplant at the U. The consortium an alliance of more than 100 academic medical centers and nearly 250
not only are more patients choosing to undergo liver transplants at University Hospital but those who are undergoing transplants are surviving at a high rate
The U. gives patients important access to doctors from specific specialties who are able to come together to focus on the specific needs of a patient said Kim and his colleague Jeff Campsen M d. Surgical Director of Pancreas Transplantation.
The high-caliber care is appreciated by patients and their families. Aspen's mother Auchelle Daniels said she'll always be grateful to the physicians who saved her daughter's life.
Before the start of the trial the patients'caregivers and physicians filled out three standard behavioral assessments:
#Artificial liver tested as potential therapy for patients with alcohol-related organ failurecedars-Sinai physicians and scientists are testing a novel human cell based bioartificial liver support system
for patients with acute liver failure often a fatal diagnosis. The quest for a device that can fill in for the function of the liver at least temporarily has been underway for decades.
A bioartificial liver also known as a BAL could potentially sustain patients with acute liver failure until their own livers self-repair said Steven D. Colquhoun MD the surgical director of liver transplantation at Cedars
The research at Cedars-Sinai involves patients with liver disease caused by acute alcoholic hepatitis a group with few therapeutic options.
The external organ support system is designed to perform critical functions of a normal liver including protein synthesis and the processing and cleaning of a patient's blood.
The filtered and treated blood is returned then to the patient through the central line. If successful a bioartificial liver could
not only allow time for a patient's own damaged organ to regenerate but also promote that regeneration.
In the case of chronic liver failure it also potentially could support some patients through the long wait for a liver transplant said Colquhoun.
Patients with kidney disease can use dialysis and those with cardiac problems have ventricular assist devices
Liver failure patients and their doctors have long been frustrated by the critical need to provide the kind of lifesaving care kidney patients are afforded by dialysis.
and causes discomfort is a common and temporary side effect experienced by the majority of lung cancer patients undergoing RT.
so that patients'do not forgo eating maintaining patients'positive nutritional status is vital during cancer treatment.
The randomized phase II trial enrolled 163 lung cancer patients at 13 cancer centers who were undergoing concurrent chemotherapy and RT.
Of the study group â0 percent of the patients had received 60 Gy of RT to the espophagus (V60.
Patients were assigned to three groups based upon treatment for esophagitis--56 patients in Arm 1 received standard supportive care;
53 patients in Arm 2 received 10 ml of Manuka honey orally four times per day;
and 54 patients in Arm 3 received one lozenge consisting of 10 ml of dehydrated Manuka honey four times per day.
After four weeks of RT treatment with and without Manuka honey patients were asked to assess their pain during swallowing using the Numerical Pain Rating Scale (NPRS) scale with a zero indicating no pain a five indicating moderate pain and a 10
in levels of pain reported by patients within the three groups (mean change scores of 2. 7 2. 1 and 2. 1 respectively;
Arm 3). Additionally researchers evaluated secondary endpoints such as the trend of the patients'pain over time opiod use adverse events weight loss quality of life dysphagia
so that patients can continue eating their normal diet said lead study author Lawrence Berk MD chief of radiation oncology Morsani School of medicine at the University of South Florida Tampa.
Currently honey cannot be recommended for every patient to use for esophagitis pain relief. However it is safe and inexpensive
so if patients want to try it there is probably little harm. Patients with diabetes should be cautious with honey
because it does have a high sugar load. Story Source: The above story is provided based on materials by American Society for Radiation Oncology (ASTRO.
Although stem cells can be a potent weapon in the fight against certain diseases simply infusing a patient with stem cells is no guarantee the stem cells will be able to travel to the injured area and work collaboratively with the cells already there.
The Cedars-Sinai Heart Institute has been at the forefront of developing investigational stem cell treatments for heart attack patients.
which a patient's own heart tissue was used to grow specialized heart stem cells. The specialized cells were injected then back into the patient's heart in an effort to repair
and regrow healthy muscle in a heart that had been injured by a heart attack. Results published in The Lancet in 2012 showed that one year after receiving the stem cell treatment heart attack patients demonstrated a significant reduction in the size of the scar left on the heart muscle.
Earlier this year Heart Institute researchers began a new study called ALLSTAR in which heart attack patients are being infused with allogeneic stem cells
which are derived from donor-quality hearts. The process to grow cardiac-derived stem cells was developed by Dr. Marbã¡
and vascular disease patients with appropriate stem cell clinical trials being conducted at Cedars-Sinai and other institutions.
The current research is part of a long-term project to use pig kidneys to make support structures known as scaffolds that could potentially be used to build replacement kidneys for human patients with end-stage renal disease.
A patient's own cells would then be placed in the scaffold making an organ that the patient theoretically would not reject.
Using pig kidneys as scaffolds for human patients has several advantages including that the organs are similar in size
and that pig heart valves--removed of cells--have safety been used in patients for more than three decades.
Alcohol can further complicate matters particularly for heart patients. Since alcohol is metabolized by the liver it can alter the way heart medications
â#¢Because sodium causes fluid retention--something especially bad for heart patients--a good rule of thumb is to avoid foods that have more than 1 mg of sodium per calorie.
and CV mortality in more than 61000 patients from the China Kadoorie Biobank who had CVD or hypertension at baseline.
Patients with CVD and hypertension should also be encouraged to consume more fresh fruit. Many western populations have experienced a rapid decrease in CVD mortality during the past several decades especially stroke mortality
Our results show the benefit of eating fruit in the healthy general population and in patients with CVD and hypertension.
because we believe that most of the current dietary guidelines for patients with diabetes do not reflect recent evidence.
In addition overweight patients with newly diagnosed type 2 diabetes who followed the Mediterranean diet had need less for antihyperglycemic medications compared with participants on a low-fat diet.
and high-protein diets improved glycemic control and cardiovascular disease risk factors in patients with diabetes compared with control diets.
This offers patients a range of options for diabetes management. Foods associated with a higher risk of diabetes include red and processed meat sugar-sweetened beverages alcohol in excess quantities and refined grains such as white flour.
Since almost all knowledge of dietary prevention and management of diabetes comes from research in developed countries more studies are needed in less developed regions to help patients with diabetes worldwide improve their health.
Nicolaou acknowledged it could be years--even decades--before an antibiotic derived from viridicatumtoxin B is available to patients.
The association will continue to encourage clinicians to use proven smoking-cessation strategies as the first line of treatment for any patient.
or by a patient who wants to utilize e-cigarettes to help them quit clinicians should not discourage their use by the patient.
However the statement stresses that clinicians be educated so they can inform patients that e-cigarettes are unregulated may contain low levels of toxic chemicals
#Fungus deadly to AIDS patients found to grow on treesresearchers have pinpointed the environmental source of fungal infections that have been sickening HIV/AIDS patients in Southern California for decades.
and compared the sequences to those obtained from HIV/AIDS patients with C. gattii infections.
The formation of so-called Th2 lymphocytes is initiated in these patients. Th2 lymphocytes contribute in great measure to the production of Ige antibodies to milk proteins.
The patient gets sensitized and may develop an allergic reaction to milk. Roth-Walter working at the department of Comparative Medicine at the Messerli Research Institute says:
because all hospitals are now smoke-free requiring patients to abstain temporarily from tobacco use. The major challenge for hospitals in providing evidenceâ based care is identifying how to sustain tobacco treatment after discharge according to background information in the article.
This trial demonstrated the effectiveness of a program to promote long-term tobacco cessation among hospitalized cigarette smokers who received an inpatient tobacco dependence intervention
and it increased by 71 percent the proportion of patients with biochemically confirmed tobacco abstinence 6 months after discharge
For cardiac patients currently waiting for organs mechanical assist devices are the only options available.
But for those patients who already have the disease antibody-based therapies could be the best treatment--it's a way to give the body's own defenses time to ramp up.
In the randomized control studies patients ate about 50 grams of nuts a day or about 1-1/2 servings.
and in today's print edition of the peer-reviewed journal Science Translational Medicine is the result of a dozen years of research with the goal of developing biological treatments for patients with heart rhythm disorders who currently are treated with surgically implanted
In the United states an estimated 300000 patients receive pacemakers every year. We have been able for the first time to create a biological pacemaker using minimally invasive methods
Originally we thought that biological pacemaker cells could be a temporary bridge therapy for patients who had an infection in the implanted pacemaker area Marbã¡
These results show us that with more research we might be able to develop a long-lasting biological treatment for patients.
and in today's print edition of the peer-reviewed journal Science Translational Medicine is the result of a dozen years of research with the goal of developing biological treatments for patients with heart rhythm disorders who currently are treated with surgically implanted
In the United states an estimated 300000 patients receive pacemakers every year. We have been able for the first time to create a biological pacemaker using minimally invasive methods
Originally we thought that biological pacemaker cells could be a temporary bridge therapy for patients who had an infection in the implanted pacemaker area Marbã¡
These results show us that with more research we might be able to develop a long-lasting biological treatment for patients.
#How gardens could help dementia carea new study has revealed that gardens in care homes could provide promising therapeutic benefits for patients suffering from dementia.
) the systematic review also found that gardens could offer welcome spaces for interactions with visitors helping to stimulate memories for dementia patients
if gardens are to be useful in the future care of dementia patients. These include understanding possible hazards that a garden might represent to residents
These results suggest that patients allergic to Alternaria can suffer an allergy attack after eating infected kiwifruit.
and raise serious implications for transplant patients those with leukemia and people who suffer from severe asthma.
He believes merging antifungal resistance in human pathogenic fungi is causing a huge threat to patients especially to those with weaken immune systems
In preliminary results in 40 patients the test could differentiate between Alzheimer's disease and non-Alzheimer's disease with 100 percent sensitivity and 80.6 percent specificity meaning that all people with the disease tested positive and most of the people without the disease tested negative.
and cerebrospinal fluid analysis requires that patients undergo invasive and often painful lumbar punctures but neither approach is quite feasible especially for patients in the earlier stages of disease he said.
Positron emission tomography or PET is the current diagnostic standard. The retina unlike other structures of the eye is part of the central nervous system sharing many characteristics of the brain.
Studies involved patients diagnosed with Alzheimer's a group with mild cognitive impairment and a group of people with no evidence of brain abnormality.
and the Floyd A. Davis professor of neurology at Rush. â#oethis could potentially be one of the safest approaches to halt disease progression in Parkinsonâ##s patients. â#â#oecinnamon is metabolized in the liver to sodium benzoate
and DJ-1 decrease in the brain of PD patients. â#The study found that after oral feeding ground cinnamon is metabolized into sodium benzoate
This research was supported by grants from National institutes of health. â#oenow we need to translate this finding to the clinic and test ground cinnamon in patients with PD.
If these results are replicated in PD patients it would be a remarkable advance in the treatment of this devastating neurodegenerative diseaseâ#said Dr. Pahan.
Parkinson's disease affects about 1. 2 million patients in the United states and Canada. Although 15 percent of patients are diagnosed before age 50 it is considered generally a disease that targets older adults affecting one of every 100 persons over the age of 60.
This disease appears to be slightly more common in men than women. Story Source: The above story is provided based on materials by Rush University Medical center.
However determining which protein in a food causes an allergic response to a patient requires time-consuming tests that often ignore rare or unexpected allergens.
The team of Hubert Girault at EPFL has developed a highly sensitive method that uses a patient's Ige to determine specifically which protein induces allergic responses in them.
First Ige antibodies from the patient's blood are isolated by interaction with magnetic beads that are coated with a different type of antibody.
and bind the patient's Ige antibodies. This takes place inside a long and narrow glass tube only 50 micrometers in diameter called a capillary.
The beads with the patient's Ige are placed then again inside the capillary. The test begins
As the milk's proteins pass over the patient's Ige antibodies the ones that cause allergies are caught by them
The beads are washed then with a strong chemical that causes the allergy-inducing protein to dissociate from the patient's Ige antibodies.
The method offers a personalized way to identify the exact proteins that can cause food allergies to a patient which can help develop an effective treatment.
and quantification of a patient's specific Ige antibodies or the laborious and resource-intensive diagnostic methods used currently.
or strengthen labor remove the placenta from a patient having a hemorrhage as well as handle many other complications that may occur in the mother or her baby.
#Cocoa extract may counter specific mechanisms of Alzheimers diseasea specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer's disease patients'brains long before they develop symptoms according to a study conducted at the Icahn School of medicine
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