Dr. Jenkins said another interesting finding of the study was that patients on the whole wheat diet seemed to have better blood flow after 12 weeks than those on the canola bread diet as measured by the Endopat test that uses a cuff on the arm similar to a blood pressure test.
and requires an outpatient visit then we are talking about a public health concern that is very real said Kasson.
#Tomato pill improves function of blood vessels in patients with cardiovascular diseasea daily supplement of an extract found in tomatoes may improve the function of blood vessels in patients with cardiovascular disease according to new research from the University of Cambridge.
and stroke in patients at high cardiovascular risk or those who have had previously the disease.
Thirty-six cardiovascular disease patients and thirty-six healthy volunteers were given either Ateronon (an off-the-shelf supplement containing 7mg of lycopene) or a placebo treatment.
The patients with cardiovascular disease were all on statins (cholesterol-lowering drugs. However despite this they still had impaired a relatively function of the endothelium--the inner lining of blood vessels--compared to healthy volunteers.
The researchers found that 7mg of oral lycopene supplementation improved and normalised endothelial function in the patients but not in healthy volunteers.
We've shown quite clearly that lycopene improves the function of blood vessels in cardiovascular disease patients adds Dr Cheriyan.
whether the beneficial effects seen in this small study translate into clinical benefit for at-risk patients.
While the focus of this study was the impact of maternal Vitamin b12 deficiency on offspring in mouse models there are promising parallels between these findings and data from human patients.
In addition older patients with Vitamin b12 deficiency from a study by the Institute for Molecular Medicine Finland displayed a statistically positive correlation suggesting that Vitamin b12 plays a key role in regulating taurine synthesis and bone formation in humans of all ages.
The multifaceted interactions between diet nutrition and oral health in practice education and research in both dietetics and dentistry merit collaborative efforts to ensure comprehensive care for patients and clients according to the practice paper's authors.
and nutrition practitioners to educate their patients and clients on important aspects of nutritional health that lead to oral health:
Dermatologists generally don't treat many patients with mild acne because those problems can be cleared up by the proper use of consumer products
The treatment depends on the severity of the acne the type of acne where it's located and the patient's individual preference and motivation for treatment.
But these multilayered approaches that are tailored to the individual patient do work well. Dermatologists also have advanced ways to treat scarring including chemical peels microdermabrasion and laser technologies.
But no matter how understanding dermatologists are they--like other clinicians--face the problem of getting patients to follow their instructions.
and encouraging text messages can help increase teenage patients'proper use of acne medications Consistency is the whole key to treating acne Taylor said.
to treat seriously burned patients. A team of investigators from Massachusetts General Hospital (MGH) report that skin grafts from pigs lacking the Gal sugar molecule were as effective in covering burn-like injuries on the backs of baboons as skin taken from other
A key component in the treatment of major burns particularly those involving more than 30 percent of the body surface is removing the damaged skin and covering the injury preferably with a graft of a patient's own tissue.
and are rejected eventually by a patient's immune system. Once a deceased-donor graft has been rejected a patient's immune system will reject any subsequent deceased-donor grafts almost immediately.
The current study was designed to investigate whether a resource already available at the MGH might help expand options for protecting burned areas following removal of damaged skin.
As with the use of second deceased-donor grafts to treat burned patients a second pig-to-baboon graft was rejected rapidly.
not only of providing an alternative to deceased-donor skin for many patients but also that in patients
#Healthy diet linked with better lung function in COPD patientssure everyone knows a healthy diet provides lots of health benefits for patients with respiratory diseases
but now a new study has shown a direct link between eating fish fruit and dairy products and improved lung function among patients with chronic obstructive pulmonary disease (COPD).
. and Europe the study specifically looked at COPD patients'lung function within 24 hours of eating grapefruit bananas fish and cheese.
This study demonstrates the nearly immediate effects a healthy diet can have on lung function in in a large and well-characterized population of COPD patients Hanson said.
It also demonstrates the potential need for dietary and nutritional counseling in patients who have COPD.
#Transplant programs produce high one-year survival ratesin the latest national report on organ transplant outcomes patients receiving a new liver at the Cedars-Sinai Comprehensive Transplant Center had the best one-year
survival outcomes of all hospitals in the Los angeles region with 90%of liver transplant patients surviving beyond that important milestone.
Patients receiving new kidneys at the medical center also did extremely well with 97 percent of them surpassing the one year bench mark.
At the Comprehensive Transplant Center we have a commitment to include care for the very sickest high risk patients in need of a lifesaving organ transplant.
The success with kidney transplant patients is given particularly noteworthy the number of very ill people who come to the medical center with a high probability of rejecting a donor organ because of high amounts of antibodies in their blood.
The fact that nearly all of our kidney transplant patients are thriving one year later indicates the research
and it accepts some of the sickest most chronically ill lung patients from around the country.
and researchers here so we can offer patients in critical need of a lung transplant the highest level of care with the expectation of the best possible outcomes for them said Paul Noble MD director of the Women's Guild Lung Institute at Cedars
and nearly 90 percent of those patients are alive and doing well one year after getting a new heart according to the latest report.
and quality of our patients'lives said Klein. Story Source: The above story is provided based on materials by Cedars-Sinai Medical center.
and anti-fibrotic properties of pirfenidone offers help and encouragement to so many patients suffering from this relentless disease that robs them of breath
and scar leaving patients with shortness of breath a chronic cough and extreme fatigue. Most patients die within two to five years of diagnosis. Not only did pirfenidone prevent the loss of lung function
and preserve the distance patients could walk but during the study the risk of death was reduced by a remarkable 48 percent in those taking the drug
when compared with those who received placebo said Noble. The findings were so strong that an early access program has been initiated to provide patients with pirfenidone
while the process of obtaining FDA approval is undertaken. Cedars-Sinai will be participating in this program under the direction of Dr. Jeremy Falk and the Advanced Lung Disease Program.
Noble also was a co-author of a second study testing the efficacy and safety of the multi-kinase inhibitor nintedanib on idiopathic pulmonary fibrosis patients.
In our research we found that nintedanib could also slow the loss of lung function in patients with idiopathic pulmonary fibrosis said Noble.
It is a second dose of good news for our patients because nintedanib not only slowed the progression of the disease
while tending to preserve the quality of life of the study patients receiving the drug. Noble is paid a consultant of Intermune Inc
and hard work required to find treatments for a group of patients who have so few therapeutic options
The Comprehensive Cancer Center of Wake Forest Baptist Medical center is one of only a handful of cancer centers that is attempting to give lung cancer patients out of treatment options a chance to keep the cancer at bay.
For these patients hope lies in a second course of treatment â#repeat radiation. Two complementary papers published back-to-back recently in the journal Radiotherapy
what to do for patients when the cancer comes back in an area thatâ##s been treated previously with radiation treatmentâ#said James J. Urbanic M d. lead author of the studies
â#Urbanic said the overall findings of the study suggest that there are some patients with recurrent lung cancers who can be treated with another definitive course of radiation therapy
and still have a chance at a cure. â#oeat many cancer treatment centers these patients only get chemotherapy
Itâ##s a layer of hope for some patients that they never had before. â#For this study the researchers looked back at 11 years of clinical data.
Eighty-six patients were identified who received at least two courses of thoracic radiotherapy. Of that number 33 were treated with repeat thoracic radiotherapy using stereotactic body radiation therapy (SBRT) or accelerated hypofractionated radiotherapy (AHRT) as a component of their treatment.
and the majority of patients (88 percent) were treated for primary lung cancer. Average tumor size at retreatment was 2. 5 cm.
Prior lung resections had been completed in 24 percent of patients. Urbanic said the typical patient is an older man
or woman who got treated with either chemotherapy and radiation or radiation alone for a lung cancer that couldnâ##t be removed surgically.
If the cancer is just in one spot the patients get retreated with 10 radiation treatments done with the SBRT technique
and minimizes the dose to the surrounding normal tissue. â#oewake Forest Baptist has been developing expertise in doing thisâ#Urbanic said. â#oeweâ##re finding that there are patients who are alive years later.
The gel shows potential as a bioscaffold to support the regrowth of bone and other three-dimensional tissues in a patient's body using the patient's own cells to seed the process.
but when injected into a patient becomes a gel that would fill and stabilize a space
Among a group of primarily obese African american female patients in southwest Georgia researchers looked at food inventories food placement grocery shopping food preparation meal serving practices family
if the amounts of the drugs can be tailored to match the metabolic profile of a patient's tumor.
Patients with this profile had the worst prognosis for survival. The three-year study included cell culture studies at Rice as well as a detailed analysis of gene expression profiles of more than 500 patients from the Cancer Genome Atlas and protein-expression profiles from about 200
MD Anderson patients. The enzyme glutaminase is key to glutamine uptake from outside the cell
and glutaminase is the primary target that everybody is thinking about right now in developing drugs Nagrath said.
but because antibiotic resistance in human infections is such a serious global health problem that has led to higher patient mortality rates prolonged hospitalization
Therefore for the cardiac patients currently waiting for organs mechanical assist devices are the only options available.
of patients waiting for human donor organs comments Dr. Mohiuddin. The NHLBI group was fortunate to have access to GE pigs through close collaboration with Revivicor Inc. Experiments using these GE pig hearts transplanted in the abdomen of baboons
That might signal good news that AR genes from cow gut bacteria are not currently causing problems for human patients.
and could lead to more weight loss among patients says Lisa Graham lead author of a study by researchers from Leicester Royal Infirmary in the UK.
Their findings published in Springer's journal Obesity Surgery showed that after gastric bypass surgery patients frequently report sensory changes.
Graham and her colleagues say their day-to-day experience with patients who have undergone gastric bypass surgery suggested these changes
To this end questionnaires were sent out to patients who had undergone the procedure at the University Hospitals of Leicester between 2000 and 2011.
In total 103 patients answered the 33 questions about appetite taste and smell set to them.
Seventy-three percent of patients noted change in the way food tasted and especially in their sweet and sour palate.
Three out of every four (73 percent) patients noted that they had developed an aversion to specific foods after the surgery.
Meat products topped the list with one in every three patients steering away from chicken minced beef beef steak sausages lamb ham or bacon.
Interestingly patients who experienced food aversions enjoyed significantly more postoperative weight loss and reduction in their body mass index (BMI) compared to their counterparts without such dislikes.
Patients are counselled routinely about the potential loss of taste and smell in consenting for surgery.
In between collecting data and analyzing results they overcame the long waiting periods by being patient encouraging each other
and degenerative spine problems resulting in fewer complications and better outcomes for patients. The Cedars-Sinai surgeons highlight the advantages of a spinal navigation technique that uses high-speed computerized tomography (CT) imaging to navigate in and around the spinal column from different angles.
while a patient is in surgery. The images are transferred to a computer which displays them on overhead monitors that allow precise tracking of surgical instruments as surgeons insert screws for reconstruction
#Patients with gluten intolerance: New therapies possibleresearchers at Mcmaster University have discovered a key molecule that could lead to new therapies for people with celiac disease an often painful and currently untreatable autoimmune disorder.
which is present in the intestine of healthy individuals is decreased significantly in patients with celiac disease.
School of medicine. â#oethere is need a great for a therapy that will protect patients with celiac disease from these accidental contaminations. â#Verdu says the results raise the possibility of elafin administration
Recently gluten intolerance has been reported in patients who do not have celiac disease (non-celiac gluten sensitivity.
cessation counseling ratessmartphones and tablets may hold the key to getting more clinicians to screen patients for tobacco use
Using mobile phones loaded with tobacco screening guidelines prompted nurses to ask patients about their smoking habits in 84 percent of clinic visits
Currently U s. patients are screened for tobacco use in about 60 percent of office visits and smokers are advised on how to quit less than 20 percent of the time according to the Centers for Disease Control and Prevention (CDC).
Clinic patients were treated by 185 registered nurses enrolled in advanced practice degree programs at Columbia Nursing. While overall screening and counseling rates were increased by use of the mobile tools the gains varied by race gender and payer source the study found.
when patients were female or African-american and at clinics where the predominant payer source was Medicare Medicaid or the State Childrenâ##s Health insurance Program.
Screening was also more likely for patients with private insurance than for patients who were uninsured
which patients are most likely to benefit from intervention. â #While the study included only patients seen by nurses who had access to mobile health tools the screening
and counseling rates in the study are much higher than the baseline rates tracked by the CDC Cato says.
Patients diagnosed with precancerous cells or lesions may take tamoxifen anywhere from three months to five years.
Not everyone can be a transplant donor so this is a way those patients who truly want to be donors can contribute to research.
and a total of 8 patients died. Experts from the University of Veterinary medicine Vienna analysed the genomes of the outbreak strains
In Austria health care providers are required to report all cases of listeriosis which can be fatal particularly for patients with weakened immune systems.
The samples were taken from listeriosis patients from the outbreak. The first contamination event from June 2009 to January 2010 was attributed to one L. monocytogenes strain very effective at infecting epithelial cells of the intestine and liver cells.
Everyone is very creative patient and supportive and there is a lot of innovation. It is exciting to learn from all of the team members.
and shows the immense potential of applying these technologies for future patients said Tyler Mark Pierson MD Phd a pediatric neurologist and member of the Department of Pediatrics and the Department of Neurology at Cedars-Sinai.
when he was introduced to the patient and his family. The child was seen first at the NIH-UDP
The patient had experienced treatment-resistant seizures since 3 months of age which caused significant issues with brain development resulting in global developmental delay.
The discovery required an analysis of the patient's genetic makeup in search of the one gene that changed setting this detrimental series of events in motion.
Based on the lab studies memantine gradually was added to the patient's regimen which included three anti-seizure drugs that had provided little or no control.
which reduces quality of life considerably as patients perceive it as particularly bothersome. For quite a long time IBS was believed to be a primarily psychological condition.
and--in nearly all patients--bloating. IBS affects up to 20 percent of the population in Western countries.
Within the range of IBS troubles it is bloating that bothers patients most. A microbiota-based conditionfor quite a long time not only bloating
but IBS in general was perceived frequently as a mainly psychological condition mostly affecting young predominantly female and anxious patients with no detectable abnormalities in their bowels.
which characterizes a healthy gut microbiota is disturbed in IBS patients. Probably the best example of this interaction is the discovery that IBS symptoms develop in up to 10 percent of previously healthy subjects after a single episode of gastroenteritis caused by an infection through bacterial pathogens like Salmonella Shighella or Campylobacter
in the microbiota of IBS patients thus prolonging and increasing the symptoms However at the same time the gut microbiota of healthy subjects remained stable
Barbara points to is that those IBS patients who have several clear-cut gut symptoms have also more profound changes in their gut microbiota as compared to other patients
whereas the condition of the patients belonging to the first group is based predominantly physiologically--IBS proper so to speak.
and patients expect? It is amazing to see how quickly gut microbiota research has gained center stage within gastroenterology in the course of the past few years says Prof.
In the study Group Health patients who were had overweight and hypertension were more likely to have lost 10 pounds in six months
One patient said'It's like having a dietitian in your pocket'said Beverly B. Green MD MPH a family doctor at Group Health an associate investigator at Group Health Research Institute and an assistant clinical
The patients really loved this intervention --and having access to a dietitian to work with them toward a healthier lifestyle.
In addition to team-based care led by a dietitian the patients in the intervention group were given a home blood pressure monitor a scale and a pedometer.
The DASH diet is not about eating less food just more of the right food Dr. Green said quoting a patient who said:
The visit to the dietitian was followed by planned follow-up by secure messaging (through Group Health's website for patients) to report their blood pressure weight
When appropriate the dietitians also encouraged patients and their doctors to consider changes to their hypertensive and lipid-lowering medication dosages.
Although the pharmacists helped patients set lifestyle goals weight loss was not statistically significant. That's why Dr. Green launched the e-Care study.
We're planning a larger randomized controlled trial where we will tailor the e-care for the patients who have hypertension Dr. Green said.
We'll pair each patient with either a pharmacist or a dietitian depending on their individual needs.
but the advantage of cork tree extract available as a dietary supplement in capsule form is that it already has been established as safe for use in patients.
In a promising prostate cancer clinical study of 24 patients that Dr. Kumar helped spearhead all the patients tolerated the treatment well he said.
and with more funding they plan to expand the study to a much larger group of patients.
#Asthma drug aids simultaneous desensitization to several food allergies, study findsan asthma drug accelerates the process of desensitizing patients with food allergies to several foods at the same time a new study
Patients who took the asthma drug omalizumab became desensitized to multiple food allergens at a median of 18 weeks;
In oral immunotherapy the desensitization method used in both studies allergic patients build up tolerance to a food by ingesting it in tiny gradually increasing doses under a doctor's supervision in a hospital setting.
and the patient is able to eat the food safely. Several researchers have shown that this therapy works on a single food allergen
Patients'options for dealing with food allergies are limited. Physicians advise them to avoid allergy triggers
In prior studies patients took as long as three years to become desensitized to one food. being desensitized to several foods one at a time could prospectively take decades.
Yet Stanford researchers succeeded in safely desensitizing patients to several food allergens at once and were able to speed up desensitization by supplementing oral immunotherapy with injections of omalizumab (brand name Xolair).
In the earlier study in which patients were given not omalizumab 25 children and adults with multiple allergies ate tiny doses of their allergens--as many as five--as highly purified food powders each day.
Eight weeks before being introduced to food allergens the patients began receiving injections of omalizumab. This drug reduces activity of the body's Ige molecules the antibodies involved in allergic responses
Patients getting omalizumab tolerated larger initial doses of allergens than those in the non-omalizumab study
The patients continued consuming food powders until they could safely eat 4 grams of each food protein.
'Bystander effect'We saw this'bystander effect'in about 60 percent of patients where for example we gave someone pecan powder
and Vodovotz on the cancer study says that she is amazed that the food scientist team was able to engineer such a potent concoction that patients also seemed to enjoy.
The study also showed that active levels of antioxidants were appearing in patient's tissues
This is especially true at the clinical setting where physicians might ask patients if they smoke
and patient fail to identify themselves as smokers. In their cross-sectional analysis of the 2011 California Longitudinal Smokers Survey Al-Delaimy and colleagues defined NIS as persons who had smoked at least 100 cigarettes in their lifetime reported smoking at least one day
whether samples taken from the stool of a patient contain genetic DNA from the parasite that causes the disease.
They call for improved labeling similar to those on food to help inform doctors pharmacists and patients about the content of medicines.
And they stress that concerned patients should not stop taking their medication without consulting their doctor first.
Yet many patients and doctors are unaware that commonly prescribed drugs contain animal products --and simply reading the list of ingredients will not make it clear
whether the product meets the patient's dietary preferences. Problem ingredients include lactose (often extracted using bovine rennet) gelatine (sourced from cows pigs
Our data suggest that it is likely that patients are unwittingly ingesting medications containing animal products with neither prescriber nor dispenser aware they write.
and they would limit the exposure of patients to products they find unacceptable they conclude.
The study compared 360 patients with Parkinson's in three agriculture heavy Central California counties to 816 people from the same area who did not have Parkinson's.
or slow its progression particularly for patients exposed to pesticides the study states. The study was funded in part by the National Institute of Environmental Health Sciences (P01es016732 R01es010544 5r21es16446-2 and U54es012078) the National Institute of Neurological disorders and Stroke (NS038367) the Veterans Administration Healthcare
#Gastric bypass improves insulin secretion in pigsthe majority of gastric bypass patients mysteriously recover from their type 2 diabetes within days before any weight loss has taken place.
Until now it has been a mystery why patients'blood sugar levels normalise. The group at Lund University Diabetes Centre found that the pigs'beta cells improve their insulin secretion.
The results which were published online this week in the open-access journal PLOS ONE came from a 10-month study of 87 patients at Queen Elizabeth Central Hospital (QECH) in Blantyre Malawi.
Patients were treated with bubble CPAP whenever a machine and trained staff were available. The study included data from 62 infants who were treated with bubble CPAP
and subpial cortical lesions exclusively observed in MS patients but not fully understood says Linden.
when DDT breaks down were higher in the blood of late-onset Alzheimer's disease patients compared to those without the disease.
and the University of Texas Southwestern Medical school's Alzheimer's disease Center 74 out of the 86 Alzheimer's patients involved
Patients with a version of Apoe gene (Apoe4) which greatly increases the risk of developing Alzheimer's
and high blood levels of DDE exhibited even more severe cognitive impairment than the patients without the risk gene.
#Clinical trial studies vaccine targeting cancer stem cells in brain cancersan early-phase clinical trial of an experimental vaccine that targets cancer stem cells in patients with recurrent glioblastoma multiforme
The Phase I study which will enroll about 45 patients and last two years evaluates safety
Immune system cells called dendritic cells will be derived from each patient's blood combined with commercially prepared glioblastoma proteins
Cedars-Sinai's brain cancer stem cell study is open to patients whose glioblastoma multiforme has returned following surgical removal.
The vaccine and study-related tests and follow-up care will be provided at no cost to patients.
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