Genome

Chromosome (6)
Genome (123)

Synopsis: 4. biotech: Genus: Genetic vectors: Genome:


BBC 01170.txt

However, this is not the only way of increasing photosynthesis. Scientists are also exploring the idea that genes from the ancestors of modern-day plants might boost the ability of crops to harness the sun. It is well known that primitive plants known as cyanobacteria have a talent

they achieved a 20%increase in tobacco plants after adding a single cyanobacteria gene called inorganic carbon transporter B (Ictb.

and colleagues from the University of Nebraska have carried out some initial tests on soybeans transformed with the same gene,

"The cost of meeting global regulatory requirements for a single gene engineered into a crop can run into many millions,

which has been engineered with genes from daffodils and bacteria to produce beta-carotene, a nutrient that the body can convert into Vitamin a.

But rather than importing genes from another organism researchers are now trying to find maize strains that naturally produce high levels of beta-carotene.

They then looked for any genes in these maize strains that resembled genes linked to high beta-carotene levels in other plants."

which carry a gene variant that slows down the conversion of beta-carotene to other substances,

when this sought-after gene variant is in place. Plant breeders are using the naturally occurring maize plants and those markers to breed new plants.


impactlab_2012 01297.txt

About 80 percent of canola growing along roadsides in North dakota contains genes that have been modified to make the plants resistant to common weed-killers.

80%of canola growing along North dakota roadways actually contains genetically modified genes. Eighty percent. It was hoped this wouldn t happen.

and hunger, said gene technologies would undermine the nations capacities to feed themselves by destroying established diversity, local knowledge and sustainable agricultural systems.


impactlab_2013 00259.txt

goats with spider genes that produce super-strength silk in their milk; and synthetic bacteria that decompose trash

which typically involves swapping a few genes, the scientists are building entire genomes from scratch. Keeping bar-code-stamped vials in giant refrigerators at minus-80 degrees, the company s repository in Emeryville, Calif.,is one of the world s largest collections of living

Could they tinker with some genes in the yeast to create a biological machine capable of producing medicine?


impactlab_2013 01009.txt

Such approaches could reduce the need to modify commercial crops with genes imported from other species#one of the practices that most disturbs critics of genetic modification.

a soya bean equipped with a bacterial gene that allows it to tolerate a Monsanto-made glyphosphate herbicide known as Roundup.

Putting the genes for this defense into wheat has created a crop that could trick the insects into thinking that they are in peril and drive them away.


impactlab_2013 01169.txt

Epigenetic regulation refers to the turning on and off of genes by molecules not the genes themselves.

Any random cell could reasonably be expected to have some epigenetic abnormalities, but when all of the organism s cells are derived from the same cell,


impactlab_2013 01188.txt

and interferon for multiple sclerosis and crops like Monsanto s Roundup Ready soybeans was based on relatively crude methods for inserting a gene from one organism into another.

Although it s possible to insert a single gene from one species into another, it s much harder to cut the genetic code in specific places to make real copy-editing possible.

or around a gene that might cause a disease. Right now, it s hard to study them directly.

this could be done by changing the genes of a human stem cell (in the case of a Neanderthal)


impactlab_2014 00526.txt

Gene Sequencers 114. Treatment Monitors Micro-Colleges The systems used to create colleges centuries ago seems justifiably primitive by today s standards.


Livescience_2013 03530.txt

But in clones the trophoblast cells frequently fail perhaps a domino effect from just a few genes going wrong said Jose Cibelli a stem cell researcher at Michigan State university.

and tinker with their genes turning back time to make these single-use cells pluripotent


Livescience_2013 03771.txt

Using fragments of the passenger pigeon DNA scientists could synthesize the genes for certain traits and splice the genes together into the genome of a rock pigeon.


Nature 00234.txt

Plants genes get fine tailoring: Nature Newsafter decades of searching, plant biologists have found a way to selectively snip out one gene

and replace it with another. The method promises to be a boon to both basic research

the gap can be sealed either simply in effect deleting the targeted gene or filled in with a new gene.

Zinc-finger nucleases have recently been used to create human immune cells that are resistant to HIV (see'Designer protein tackles HIV'.

Plant biologists have long been frustrated by the lack of a simple method for either deleting a specific gene from the genome or replacing it with another gene.

has not been targeted amenable to gene replacement. To have a really good model system you need targeted gene replacement,

says Joseph Ecker, a plant biologist at the Salk Institute for Biological Studies in La jolla, California.

Sporadic reports of plant gene-replacement strategies have come and gone, but none has been versatile

In 1997, a Nature paper reporting targeted gene disruption in Arabidopsis raised the hopes of many plant researchers3.

complex genomes, chock full of large families of genes with very similar DNA sequences, says Vipula Shukla, a scientific group leader at Dow Agrosciences in Indianapolis, Indiana.

That makes targeting a specific gene more difficult. The challenges associated with any kind of sequence-specific modification in plants are profound,

The team has used zinc fingers to replace a gene called IPK1 with an herbicide-resistance gene.

'Voytas's group has engineered herbicide-resistant tobacco by inserting specific mutations into a gene called Sur.

Both groups have replaced their selected genes at a frequency much higher than anyone has achieved before,

For instance, designing zinc fingers that target only one gene will probably still be a challenge,

Shukla notes that her team was able to target IPK1 without affecting a 98%-identical gene called IPK2.

Voytas'team was also able to target their gene without hitting another gene that is 96%identical.

But Voytas adds that some of the zinc-finger nucleases the team studied did cleave both genes,


Nature 02517.txt

The bacterium Agrobacterium tumefaciens which can cause tumours on plants shuttled foreign genes into plant genomes.

Developers then used genetic control elements derived from pathogenic plant viruses such as the cauliflower mosaic virus to switch on the genes.

foreign genes can be fired into plant cells on metal particles shot from a'gene gun'.

Nevertheless, Agrobacterium is still industry's tool of choice for shuttling in foreign genes, says Johan Botterman, head of product research at Bayer Bioscience in Ghent, Belgium.

and particle bombardment is less predictable, often yielding multiple, fragmented insertions of the new gene.

which carried multiple genes for insect and herbicide resistance, were stable in the field. I would expect that by the end of the decade,

this technology will be used well by many as a way to deliver large stacks of genes to plants,

Other techniques under development insert foreign genes into designated sites in the genome, unlike the near-random scattering generated by Agrobacterium.

and Sangamo Biosciences in Richmond, California, announced that they had used enzymes called zinc-finger nucleases to insert a gene for herbicide resistance at a specific site in the maize genome (V. K. Shukla et al.


Nature 03900.txt

And in pigs, scientists have used an enzyme called a TALEN2 to scramble a gene that would normally help remove cholesterol.

RNA interference (RNAI) and TALENS are more accurate at targeting the gene in question than are earlier genetic engineering techniques.

They tried replacing the gene encoding beta-lactoglobulin with a defective form, but this proved nearly impossible

because the techniques available to introduce foreign genes into animal genomes were not precise, and misplaced genes failed to express themselves correctly.

In 2006, scientists at Agresearch in Hamilton, New zealand began to experiment with molecules that interfere with the MESSENGER RNA go-between that enables translation of a gene into protein.

In mice, they discovered a short chunk of RNA, called a microrna, that targeted beta-lactoglobulin MESSENGER RNA directly to prevent its translation.

mutations are introduced often that render the targeted gene nonfunctional.""The TALEN technology is staggeringly easy, quick,

His team used TALENS to disrupt genes encoding low-density lipoprotein (LDL) receptors. Without these receptor proteins to remove cholesterol-containing LDLS from the blood,


Nature 04218.txt

Early patents on gene-use restriction technologies later rebranded as terminator technology by activists opposed to them described a genetic modification that switched on production of a toxin that would kill off developing plant embryos.

what Kelly calls a gene-guard technology: a genetic tweak that makes production of the desired chemical dependent on a proprietary additive,

Patents owned by Monsanto required the insertion of three different genes into the plant genome.


Nature 04741.txt

In 1999, they finally produced a tasty variety that contained the Vf defence gene, bred in from an unappetizing relative.

Even armed with modern breeding techniques and 15 Â known defence genes in the apple family

instead used a gene gun to fire DNA-coated gold particles into plant cells. Some of that DNA is incorporated then into the genome.

is trying to use genes from grape varieties to engineer a wine grape that is resistant to Pierce s disease a condition caused by a bacterium that has made it difficult to grow wine grapes in the state.

even though these offspring no longer contain the engineered gene. Mackenzie thinks that the transgene triggered an epigenetic change:

"The flip side is that they are so powerful you can engineer multiple genes at one time.

He notes that Agrobacterium inserts genes more efficiently than the gene-gun method. Although zinc-fingers are appealing for their specificity

in spite of the fact that the genes he introduced came from other apples. This was used because he Agrobacterium to insert the genes it did not matter to regulators that no trace of Agrobacterium DNA remained in his plants.

Schouten is perplexed. If he had used a gene gun, he would have inserted DNA haphazardly and in a manner more likely to damage other sites in the genome yet this remains the unregulated method."

"To me, this is a very strange system, he says


Nature 04895.txt

Farmers dig into soil qualityefforts to bring chemical fertilizers to Sub-saharan africa are met often with concerns over harmful environmental and economic side effects.


popsci_2013 00407.txt

Mutation breeding is considered not genetic engineering which puts genes from one species into another species. Genetic engineering can be a quick


popsci_2013 01048.txt

and bacteria to deliver the genes into the corn so that it can produce Delta Endotoxin.

For this reason GMOS that have the Bt gene are compatible with biological control programs

if the modified gene can have complications 1000x generations down the line. Why would the government pass a bill to protect Monsanto

Just add a few beef genes here and there another bag full of bread genes. Coffee-sized machines 3d-print algae foodstuffs-precursor so we can handle the texture-hurdle. z=textstyle-frac {3}


popsci_2013 01087.txt

If an inkjet could print genes Boland thought perhaps the same hardware could print other biomaterials.

and they can be used to deliver genes and growth factors to developing cells. But as in the case of polymers they can introduce foreign materials into the body and cause inflammation.


Popsci_2014 00466.txt

The sequences of parent plants'genes represent some of the companies'most important intellectual property.


ScienceDaily_2013 05899.txt

and use the genes that we bred for in grain sorghum over the last hundred years and move them into sweet sorghum and biomass sorghum.

We think that finding those genes is going to be said critical he. Even with this complete genetic map Brown said the research is still not at the end point.

and where we've stacked the good genes. Over here we've got exotic sorghum which hasn't been improved at all yet it's where most of the genetic diversity is.

For that genetic diversity to be useful to grain sorghum we need to know where the genes are for height

or biomass sorghum researchers will need to bring in some of the genes from grain sorghum for traits like seed quality or early-season vigor.

This is the general agronomic stuff we've been breeding for not the genes for dwarfing and earliness.

Right now we're using sorghum as a model--maybe we can find sorghum genes that we can also tinker with in miscanthus

Another gene found shows that sorghum produces a huge amount of antioxidant in the outer layer of the grain.


ScienceDaily_2013 12298.txt

The new technology platform can harness the plant's own genes to improve characteristics of sunflower develop genetic traits


ScienceDaily_2013 16940.txt

and the associated antibiotic-resistant genes that find their way into the ground water and ultimately the food supply.

That means they will drop genes they're not using because there is a metabolic burden a high energy cost to keeping them.

and E coli which carries resistant genes directly from animals through their feces into the environment.

If we can put an anaerobic barrier at the point where a lagoon drains into the environment we will essentially exert selective pressure for the loss of antibiotic-resistant genes

but it's enough to have bacteria notice a deficiency in their ability to obtain energy from the environment and feel the stress to dump resistant genes.

His study of the Haihe River in China funded by the Chinese government and published last year found tetracycline resistance genes are common in the environment there as well.

Prevention here is basically don't let these genes proliferate. Don't let them amplify in the environment.


ScienceDaily_2014 00415.txt

We can measure entire root systems for thousands of plants to give geneticists the information they need to search for genes with the best characteristics.

For instance certain genes may help plants survive in nitrogen-poor soils or in areas where drought is a problem.


ScienceDaily_2014 06357.txt

In a paper published in this weekâ##s early online edition of Nature they report the discovery of a new genetic pathway in plants made up of four genes from three different gene families that control the density

and genes by which CO2 represses stomatal pore developmentâ#says Schroeder. Working in a tiny mustard plant called Arabidopsis which is used as a genetic model

and shares many of the same genes as other plants and crops he and his team of biologists discovered that the proteins encoded by the four genes they discovered repress the development of stomata at elevated CO2 levels.

and genes have the potential to address a wide range of critical agricultural problems in the future including the limited availability of water for crops the need to increase water use efficiency in lawns as well as crops


ScienceDaily_2014 13102.txt

#Instrument built to study effects of genes, environment on plant traitslet's say plant scientists want to develop new lines of corn that will better tolerate long stretches of hot dry weather.


ScienceDaily_2014 14031.txt

The research provides a new approach integrating knowledge of genes proteins plant chemical compounds and engineering modeling to understand how plants make products


WS_1452 01180.txt

GMOS oecan be defined as organisms in which the genetic material (DNA) has been altered in a way that does not occur naturally it allows selected individual genes to be transferred from one organism into another, also between non-related species. Simply put,


WS_1452 01394.txt

and reagents, including synthetic genes. The paper points out that our own Obama administration has embraced oegarage biology entrepreneurs here in the U s. The relevant document

They engineered E coli bacteria to contain sets of genes with growth hormone and also with malate, a root detector.

which involves modestly changing a few genes. By contrast, synthetic biologists work with large networks of genes,

thus a new acronym, SMO. I enjoyed Yong quote of conference organizer, Kent Redford, from the Wildlife Conservation Society,


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