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but the genome sequence revealed the potential for around 20. The known antibiotics represented only 20%of the possible total.
Researchers have copied this bacterial system to create gene-editing complexes that include a DNA-cutting enzyme called Cas9 bound to a short RNA guide strand that is programmed to bind to a specific genome sequence telling Cas9 where to make its Cut in some cases the researchers simply snip out
#Scientists construct first whole genome sequence of bighorn sheep Geneticists at the University of Alberta have constructed the first whole genome sequence of a bighorn sheep in a new study that could have a significant impact on conservation efforts of the species,
To construct a whole genome sequence, the DNA is first run through a sequencer to identify small strings of building blocks, called nucleotides.
which uses an existing genome sequence as a reference point to streamline the process. ere, one starts with the same jigsaw pieces,
In this case, the reference used for alignment was the already complete whole genome sequence of a domestic sheep.
Full genome sequences are still relatively rare; for context, only 108 mammals are listed in the National Center for Biotechnology Information database. ntil recently,
generating a genome sequence of any organism was nearly impossible, notes Miller. The majority of organisms sequenced so far have been domestic laboratory species such as fruit flies or lab mice.
and cost-effective enough to be useful in obtaining whole genome sequences of wildlife species, like bighorn sheep.
and management actions for at-risk species. Constructing a whole genome sequence of the bighorn sheep will also help by providing a reference for new studies,
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