Thanks to this substance malaria is curable. Unfortunately, it could be found only in tiny quantities in the sweet wormwood-until the US researcher Jay Keasling was able to transfer the appropriate production route from the plant in bacteria.
#A new sunblock that doesn't penetrate the skin Most commercial sunblocks are good at preventing sunburn,
the researchers tested their sunblock against direct ultraviolet rays and their ability to cause sunburn.
the researchers formulation protected equally well against sunburn. They also looked at an indirect and much less studied effect of UV LIGHT.
#Brain Friendly Interface Could Change the Way People with Spinal cord Injuries Lead Their Lives Recent research published in the journal Microsystems
and spinal cord injury lead their lives. Instead of using neural prosthetic deviceshich suffer from immune-system rejection
helping people living with limb loss and spinal cord injury become more independent. However not only do neural prosthetic devices suffer from immune-system rejection,
There is a significant burden in cost of care and quality of life for people suffering from this disability.
#Oxytocin Delivering Nasal Device to Treat Mental illness Researchers at the University of Oslo have tested a new device for delivering hormone treatments for mental illness through the nose.
About one out of every hundred Norwegians develop schizophrenia or autism in the course of their lifetime.
Many psychiatric disorders such as autism, schizophrenia and bipolar disorder are characterised by poor social functioning. Oxytocin is a hormone that influences social behaviour
and has shown promise for the treatment of mental illness. Researchers at Uio have discovered now that low doses of oxytocin may help patients with mental illness to better perceive social signals.
As part of this project, they have collaborated with the company Optinose, who have developed a new device designed to improve medicine delivery to the brain via the nose.
Medicine through the nosebecause of oxytocin role in social behaviour, researchers have explored the possibility of administering the hormone for the treatment of mental illness.
May yield new treatmentsthe next step in the research is to carry out the same tests on people with mental illness. e are now running tests in volunteers diagnosed with autism spectrum disorders,
says Dr Quintana. e hope that this research project is the first step in the development of a series of new medicines that may be of great help to more people with mental illness,
Cancer tissue, for example, is less dense than healthy tissue. The method therefore opens up the prospect of detecting tumors that are less than 1mm in diameter in an early stage of growth before they spread through the body
and exert their lethal effect. For this purpose however, researchers must shorten the wavelength of the X-rays even further
What's more, they have demonstrated the practicality of this approach by identifying a novel molecule that blocks a key enzyme used by the hepatitis C virus."Our dream is to provide a do-it-yourself method--one that can be applied by anyone,
a farmer could identify a novel combination that treats plant infections. He adds that the next step is to determine the most efficient way to screen the thousands
the results show that the pyrolysis of manure waste has other additional environmental benefits such as reduced soil nutrient leaching and less waste volume, removal of odor and pathogens of the original material.
and serve a greater number of silos with the same ozonation system providing great versatility in removing pathogens from stored grain.
#Lung'filtering'technique can reduce transplant rejection Lung transplantation is often the only option for patients with end stage lung disease,
"Because the lung is a potential entry route for infection into the body, its immune response is developed highly.
which then increases the risk of infection and cancer. These immune processes are therefore very important and contribute to the outlook where only five out of ten patients will survive for at least five years."
"Patricia Moore, 63, from Oswestry was diagnosed with idiopathic pulmonary fibrosis in 2011 and received a transplant in 2014.
"We aim to create effective and narrow-spectrum methods for targeting pathogens.""Lu and his colleagues are now designing phages that can target other strains of harmful bacteria,
as well as treating human disease. Another advantage of this approach is that all of the phages are based on an identical genetic scaffold,
diseases and higher temperatures and droughts expected to accompany climate change. Cotton growers have experienced a plateau in yields since the early 1990s
and breeders in the years ahead develop cotton varieties with improved fiber qualities, higher yields and more tolerance to heat, drought and diseases anticipated due to climate change.
developed by the Public health Agency of Canada and manufactured by the American pharmaceutical company Merck Sharp & Dome, was shown just to confer 100%protection against the disease,
One of the two currently-tested Ebola vaccines has been shown in a recent trial to provide 100%protection against the disease
said Michael Osterholm, Director of the Center for Infectious disease Research and Policy in Twin cities, Minnesota,
while current statistics on the epidemic are the most promising in well over a year last week only four new cases were observed in Guinea
One of her daughters has a usually fatal lung condition called pulmonary arterial hypertension. In addition to GM pigs, her company is carrying out research on tissue-engineered lungs and cryopreservation of organs. ee turning xenotransplantation from
saving the lives of people who would otherwise die from heart failure. In the U s. about 2, 400 heart transplant occur each year,
They had severe brain damage but were not brain dead. These patients are usually on mechanical ventilators and some,
#Tadpole endoscope offers new hope for gastrointestinal cancer detection 14 september 2015 By Stuart Nathan The problem of looking at the inside of the body is a pressing one for doctors,
Cancers in this system the oesophagus, stomach, intestines and rectum are major causes of death and difficult to investigate,
it can be difficult to determine precisely where lesions and growths are, because of mismatches between imaging speed and peristalsis,
blood clotting and bacterial infection. A team of Harvard scientists and engineers may have a solution. They developed a new surface coating for medical devices using materials already approved by the Food and Drug Administration (FDA.
Heparin is notorious for causing potentially lethal side-effects like excessive bleeding but is often a necessary evil in medical treatments where clotting is a risk.
The ability to mold inorganic nanoparticles out of materials such as gold and silver in precisely designed 3d shapes is a significant breakthrough that has the potential to advance laser technology microscopy solar cells electronics environmental testing disease
These coatings can also help scientists develop highly sensitive multiplex methods of detecting early-stage cancers
and genetic diseases by combining the chemical specificity of the DNA with the signal readout of the metal.
This capability should open up entirely new strategies for fields ranging from computer miniaturization to energy and pathogen detection.
and to aid our understanding of a range of diseases, "explained Evans. Aside from biological applications,
or to create artificial noses for the early detection of disease or simply to advise you that the milk in your fridge has gone off."
because they have a large amount of crop pathogen. However this species has other subspecies that does not harm their host plants
and treat human waste result in serious health problems and death--food and water tainted with pathogens from fecal matter results in the deaths of roughly 700000 children each year.
Linden's team is one of 16 around the world funded by the Gates Reinvent the Toilet Challenge since 2011.
and transferred to the fiber-optic cable system--similar in some ways to a data transmission line--can heat up the reaction chamber to over 600 degrees Fahrenheit to treat the waste material disinfect pathogens in both feces and urine and produce char.
The breakthrough could be important in developing effective molecules for use in a wide range of industries everything from the development of safer new drugs and disease diagnosis to less toxic pesticides.
for instance the well-known malformation of the limbs of infants of pregnant women taking the Thalidomide drug to relieve morning sickness that occurred around 1960.
In addition to the development of effective new drugs and diagnosis methods for diseases including cancer, it could potentially lead to new reenpesticides using pheromones tailored specifically to attract pollinators
and trees when under stress and detectors to identify concentrations in air samples could be used to monitor our changing ecology.
for Integrative Cancer Research. Eliana Martins Lima, of the Federal University of Goiás, is the other co-author.
which greatly increases the risk of arthritis. The scaffold isn just a plastic shell, however.
Google X is also creating contact lenses that can monitor blood glucose level to help in managing conditions like diabetes.
comparing 571 patient samples to FDA-approved samples of mumps, measles, and herpes simplex viruses 1 and 2. The platform achieved an accuracy of 99.6 percent in diagnosing mumps, 98.6 percent for measles,
and 99.4 percent each for herpes simplex 1 and 2. Schematic overview and different perpsectives of the colorimetric readeraccording to the research paper,
hand-held platform could assist healthcare professionals perform disease screening and vaccination tracking campaigns in resource-poor and field settings.
In addition to serving low-resource or remote areas, the researchers noted that intrinsic wireless connectivity can serve epidemic-related studies,
spatiotemporal maps of disease prevalence and immunity. e are always looking toward the next innovation, and are looking to adapt the basic design of this ELISA cellphone reader to create smartphone-based quantified readers for other important medical tests,
physics and astronomy, to bioengineering, pathology and laboratory medicine. The Californa Nanosystems Institute and the Johnsson Comprehensive Cancer Center also contributed, with support from the National Science Foundation and the Howard hughes medical institute.
Since 3d printing technology is acknowledged already for being affordable and easily transportable to low-resource areas,
of which are at high risk for virus-related epidemics. And, given the incredibly high success rates of the clinical trials so far, it can only be hoped that this lifesaving device is put to good use as soon as humanly possible. a
screening populations for particular diseases, or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
measles, and herpes simplex viruses 1 and 2 were all part of the dual ELISA tests. From 571 patient samples, the mobile platform was 99.6 percent accurate at diagnosing mumps, 98.6 percent for measles,
and 99.4 percent for both herpes simplex 1 and 2. ur team is focused on developing biomedical technologies that work with mobile platforms to assist with on-site testing
#Polymer Nanobrushes Grab Selected Bacteria for Pathogen Detection A Texas A&m Agrilife Research engineer and a Florida colleague have developed a biosensor that can detect listeria bacterial contamination within two
The same technology can be developed to detect other pathogens such as E coli O157: H7, she said.
But listeria was chosen as the first target pathogen because it can survive even at freezing temperatures.
It is also one of the most common foodborne pathogens in the world and the third-leading cause of death from food poisoning in the U s."It can grow under refrigeration,
000 National Science Foundation grant to continue their work on nanobrushes for pathogen detection n
#New Technique Uses Ultrasound Waves for Bulk Synthesis of Graphene A team of researchers from the University of Tabriz have developed a method to manufacture graphene, a crystalline allotrope of carbon, in a simple and economical manner.
where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses. otton is one of the most fascinating and misunderstood materials,
which could help in warding colds, flu and other diseases. Two of Hinestroza students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Malaria kills more than 600,000 people annually in Africa. While insecticide-treated nets are common in African homes
The nanoparticles infused with silver ions were utilized to attack Pseudomonas aeruginosa, disease-causing bacteria; E coli, a bacterial species that cause food poisoning;
and Ralstonia, a genus of bacteria that contains various soil-borne pathogens. All these bacteria were destroyed by the newly developed nanoparticles.
for Integrative Cancer Research. Eliana Martins Lima, of the Federal University of Goiás, is the other co-author.
The Saturas sensor provides accurate information for optimized irrigation to reduce water consumption with no stress to the plants and increases fruit production and quality.
Insulin for people with diabetes has been made in genetically modified bacteria for decades. But there are concerns these latest advances could allow a DIY drug lord to brew illegal narcotics in their home."
manufactured by the US firm Second sight, has previously been used to restore some vision to patients who are blind as a result of a rare condition known as retinitis pigmentosa.
Scientists see the technology being used in remote laboratory settings to diagnose cancers and central nervous system disorders such as Alzheimer
and to detect drug resistance in infectious diseases. Bringing techniques and testing that is normally confined to a laboratory or hospital, out into the field,
such as diagnosing and tracking Malaria and TB. It can also be applied to blood diseases, like sickle cell anemia,
or be used to look at contamination, for example in food or milk. The team has been able to convert the mobile phone into a sensitive E-coli or giardia detector,
one of the most frequently encountered pathogens, Ozcan said. It can also be used for simple tests that are done normally only at hospitals
for example, look at a Malaria infected patient, or TB infected patient and potentially decide on a drug choice based on some of the genetic testing copy number variations of certain genes that you would find in the sample taken from the patient. he technology also removes barriers to testing that cities
For example, someone with diabetes who has chronic kidney problems. If the person needed to be tested every few hours, before a meal, after a meal,
and our aging population. ext up the researchers plan to test their device in the field to detect the presence of malaria-related drug resistance.
ELISA can detect a number of diseases, including HIV, West nile virus and Hepatitis b, and it is used widely in hospitals.
screening populations for particular diseases, or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
The ELISA tests included those for mumps, measles, and herpes simplex viruses 1 and 2. With a total of 571 patient samples used in the comparison,
the mobile platform achieved 99.6 percent accuracy in diagnosing mumps, 98.6 percent for measles, and 99.4 percent each for herpes simplex 1 and 2. ur team is focused on developing biomedical technologies that work with mobile platforms to assist with on-site testing
The UCLA team included researchers from electrical engineering, physics and astronomy, bioengineering, pathology and laboratory medicine,
as well as the California Nanosystems Institute and the Jonsson Comprehensive Cancer Center. The other authors on the paper were UCLA graduate students Bingen Cortazar, Derek Tseng, Haydar Ozkan, Raymond Yan-Lok Chan, and Steve Feng;
while it is kept at a consistent warmth of 101.5°F (38°C). The three-plus weeks the manure is kept at that temperature is to guarantee any pathogens would be killed off,
000 people in Britain, 85 per cent of them with the dry form of the disease.
and his brain now needs to get use to interpreting it. he Argus II retinal implant was used previously on 130 patients with the rare eye disease retinitis pigmentosa.
At the same time, however, the mechanical stress on the products needs to be kept as low as possible,
and stress signals that is otherwise invisible to the human eye. The crop health monitoring imagery utilized by Farmlogs shows information that is actionable
#World First Malaria Vaccine Approved and it Will be Not-for-Profit The world first malaria vaccine has been given approval by a European medical agency for future use in Sub-saharan africa, where more than a quarter million children under the age of five die every year from the disease.
European regulators examined phase III clinical trial results involving more than 16,000 young children conducted by research centers in eight African countries (Burkina faso, Gabon, Ghana, Kenya, Malawi, Mozambique, Nigeria
with all that money going back into further research for a malaria vaccine that could be even more effective.
along with current Malaria prevention techniques, like bed nets. 80%of the children involved in the clinical trials were protected also by insecticide treated bed nets.
malaria cases were reduced by almost half in children aged 5-17 months at the time of first vaccination and by 27%in infants aged 6-12 weeks.
At study end, over four years of follow-up in children RTS, S reduced malaria cases by 39,
In areas of the highest malaria burden, more than 6 000 clinical malaria cases were prevented over the study period for every 1, 000 children vaccinated
#The Case for Long-Duration Storage: Net Electricity Load in Calif. Is 5 Years Ahead of Schedule On January 11, 2015, a rather unremarkable Sunday earlier this month,
If the rods and cones that make up the photoreceptors of the eye fail because of injury or illness,
and has restored already the sight of people with a specific form of blindness. About 200,000 people in the US have inherited diseases that cause problems for the photoreceptors in their eye.
From strings of lights adding holiday cheer to artificial sunlamps alleviating seasonal affective disorder, they brighten our days.
how proteins aggregate in the earliest stages of diseases like Alzheimer and Huntington, has begun just.
Understanding disease progression at the single-molecule level could help identify when early intervention might be advantageous.
Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
"The team tested the therapeutic potential of the nanoparticles by loading them with an anti-melanoma drug
In further experiments, the researchers found they could alter the infusion of the particles into melanoma cells by adjusting the polymer coatings.
"This is a versatile platform to carry a multitude of drugs-for melanoma, for other kinds of cancers and for other diseases,
Remote-controlled Eradication of Astrogliosis in Spinal cord Injury via Electromagnetically-induced Dexamethasone Release from"Smart"Nanowireswen Gao and Richard Borgenswe describe a system to deliver drugs to selected tissues continuously,
and deposited onto a spinal cord lesion in Glial fibrillary acidic protein-luc Transgenic mices (GFAP-luc mice). Overexpression of GFAP is an indicator of astrogliosis/neuroinflammation in CNS injury.
The corticosteroid DEX, a powerful ameliorator of inflammation, was released from the polymer by external application of an Electromagnetic field for 2 hours/day for a week.
and wires required by other implantable devices that can lead to infection and other complications, said team leader Richard Borgens, Purdue University's Mari Hulman George Professor of Applied Neuroscience and director of Purdue's Center for Paralysis Research."
"This tool allows us to apply drugs as needed directly to the site of injury, which could have broad medical applications,
"Borgens said.""The technology is in the early stages of testing, but it is our hope that this could one day be used to deliver drugs directly to spinal cord injuries, ulcerations, deep bone injuries or tumors,
and avoid the terrible side effects of systemic treatment with steroids or chemotherapy.""The team tested the drug-delivery system in mice with compression injuries to their spinal cords
and administered the corticosteroid dexamethasone. The study measured a molecular marker of inflammation and scar formation in the central nervous system and found that it was reduced after one week of treatment.
Wen Gao, a postdoctoral researcher in the Center for Paralysis Research who worked on the project with Borgens
and transported a patch of the nanowire carpet on water droplets that were used used to deliver it to the site of injury.
The nanowire patches adhere to the site of injury through surface tension Gao said. The magnitude and wave form of the electromagnetic field must be tuned to obtain the optimum release of the drug,
Youngnam Cho, a former faculty member at Purdue's Center for Paralysis Research; and Jianming Li, a research assistant professor at the center.
GFAP is expressed in cells called astrocytes that gather in high numbers at central nervous system injuries. Astrocytes are a part of the inflammatory process and form a scar tissue,
A 1-2 millimeter patch of the nanowires doped with dexamethasone was placed onto spinal cord lesions that had been exposed surgically,
The lesions were closed then and an electromagnetic field was applied for two hours a day for one week.
###The research was funded through the general funds of the Center for Paralysis Research and an endowment from Mrs. Mari Hulman George. Borgens has a dual appointment in Purdue's College of Engineering and the College of Veterinary medicine.##
Cancer Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015news and information Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015sweeping lasers snap together nanoscale geometric grids:
New technique creates multilayered, self-assembled grids with fully customizable shapes and compositions June 23rd,
2015nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015newly-Developed Biosensor in Iran Detects Cocaine addiction June 23rd,
2015discoveries Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015sweeping lasers snap together nanoscale geometric grids:
2015announcements Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015sweeping lasers snap together nanoscale geometric grids:
2015nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015iranian Scientists Design Nano Device to Detect Cyanogen Toxic Gas June 23rd,201 0
4-D printing to advance chemistry, materials sciences and defense capabilities June 18th, 2015discoveries Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015sweeping lasers snap together
its high concentration causes digestive malfunctions and results in the related diseases due to its toxicity.
chemotherapy packed nanoparticles may target cancer stem cells June 30th, 2015graphene flexes its electronic muscles: Rice-led researchers calculate electrical properties of carbon cones, other shapes June 30th,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
if a poor state of health is caused by disease or a lack of water anyway,
They contribute to the early detection of diseases that affect grapevines, such as flavescence dore and black wood, declares Stefano Sgrelli, Ceo of Salt&lemon.
where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses.
which could help in warding colds, flu and other diseases. Two of Hinestrozas students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Malaria kills more than 600,000 people annually in Africa. While insecticide-treated nets are common in African homes
Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics like catheters in the human body.
for Integrative Cancer Research. Eliana Martins Lima, of the Federal University of Goiás, is the other co-author.
However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration.
Now, researchers at MITS Koch Institute for Integrative Cancer Research and Massachusetts General Hospital (MGH) have created a polymer gel that overcomes this safety concern
as there is a greater risk for fracture if a device is too large or too complex.
The researchers also say that single-administration delivery systems for the radical treatment of malaria
and other infections could significantly benefit from these technologies. In a March 2015 commentary piece in Nature("Perspective:
Special delivery for the gut"),Traverso and Langer wrote that the GI TRACT is an area rife with opportunity for prolonged drug delivery in tackling this global health problem.
"At present, if you lose an arm, a leg or soft tissue as part of cancer treatment or burns,
but what about that time you had measles or was it chicken pox? Your blood knows:
It could also be used to identify links between viral infections and mysterious diseases like chronic fatigue syndrome.
and could help doctors identify hidden infections.""A lot of people have hepatitis C, for example, without realising,"says Elledge.
You could imagine routinely screening people in this way, he says. To develop Virscan, Elledge and his colleagues used an international database to look up all viruses known to infect humans around 1000 strains from 206 viral species. Using this information,
so you might not find a strong antibody response in the early stages of an infection.
as a result of an infection and those triggered by a vaccine. Instead the technique might be useful in outbreaks of new viruses. Understanding how our immune system responds to other viral fragments might reveal clues as to
For example, Elledge's team will be collaborating with another group to test people with chronic fatigue syndrome,
to see if they might have been infected with any of the same viruses."Multiple sclerosis is wheeled usually out as being linked to a virus,
He envisages screening wild populations of animals thought to be linked to emerging diseases.""You could test the wild bat population to get a good idea of
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