which could boost our ability to track the spread of diseases such as cancer. Humar and his colleagues developed three ways to get cells to emit visible light.
Viruses there contaminated a plant where bacteria were used to make drugs for two rare genetic disorders, Gaucher disease and Fabry disease, cutting off supplies.
so the only way to cut down on incidences of the disease is to decrease the number of mosquitoes that carry it.
reducing the population of the disease-carrying insects by 95 percent, according to a study published last week in PLOS Neglected Tropical diseases.
Since dengue is primarily spread through the mosquito species Aedes aegypti, Oxitec has engineered a male mosquito that, to female mosquitoes in the wild, looks just like the usual males.
or transmit the disease. Juazeiro, a city in northeast Brazil, was a great place to try them out.
dengue has been on the rise in Brazil, with an estimated 16 million new cases every year.
Many of the mosquitoes that carry the disease are also resistant to pesticides, which meant that Brazilians were left with few options to decrease dengue prevalence.
The neighborhood in which the researchers tested the modified mosquitoes was a low-income area with high rates of dengue infection
according to local public health officials. Over a one-year period, the researchers released the modified males into the local environment
In the course of that year, the number of disease-carrying mosquitoes decreased by 95 percent as compared to a control group in a neighborhood next door.
This isn Oxitec first attempt to decrease the prevalence of disease-carrying mosquitoeshe company did another trial in the Cayman islands in 2010ut this test was the most successful.
The researchers hope to scale up their efforts to eradicate dengue and the insects that carry it in a larger area n
and reduce anxiety. They recently launched a Kickstarter campaign to turn their prototypes in to consumer-ready models,
and a microwave Carbon nanoparticles can be incredibly useful in the treatment of many types of disease,
"That clinical use involves the carbon spheres being coated with polymer-a polymer that can gradually release drugs into the system to fight cancer and other diseases.
"This is a versatile platform to carry a multitude of drugs-for melanoma, for other kinds of cancers and for other diseases,"says Rohit Bhargava."
"You can coat it with different polymers to give it a different optical response. You can load it with two drugs,
which is not only responsible for the high associated with the drug-plus hallucinations, delusions, memory loss, and feelings of anxiety or calm-it also been shown to slow tumour growth in mice.
And now, scientists have figured out that the mechanisms by which the drug delivers its desired medical effects
the researchers figured out that negative psychological side-effects of the drug, such as memory defects, mood swings, anxiety,
and paranoia, were triggered by a single pathway in the brain that was separate from the pathway that triggers the drug cancer-killing properties.
when babies were placed on their backs to reduce the risk of sudden infant death syndrome, the incidence of plagiocephaly--commonly known as flat head--have risen dramatically.
because with the lower surface tension we expect less risk of head flattening and less risk for pressure ulcers."
and in humans to treat viral infections that antibiotics are powerless to cure. My kids are now 15 and 13
The percentage of infections caused by the bacterium Staphylococcus aureus that have proven resistant to treatment has risen steadily from just over 2 percent in 1975 and 29 percent in 1991 to more than 55 percent today--resulting in more than 11000 deaths in the U s. each year a higher death
The drugs called propargyl-linked antifolates show promise as a treatment for MRSA infections but have yet to be tested in humans.
The researchers are now using their algorithm to predict resistance mutations to other drugs designed to combat pathogens like E coli and Enterococcus.
We might even be able to coax a pathogen into developing mutations that enable it to evade one drug
Their computational approach could be especially useful for forecasting drug resistance mutations in other diseases such as cancer HIV
and influenza where raising resistant cells or strains in the lab is more difficult to do than with bacteria the researchers say.
Professor Mahiran said in pharmaceuticals an innovation has produced successfully a drugs delivery method to penetrate the'blood brain barrier'especially for diseases that are associated with the brain such as Alzheimer Parkinson epilepsy and meningitis.
--and can perhaps be used to target unsavory antibiotic resistance genes in bacterial pathogens and occasionally in beneficial bacteria.'
or even prevent many of the blunt-force injuries we see today.""Seepersad led the work along with UT Austin research scientist Michael Haberman.
Researchers develop a faster way to treat the heart after a heart attack Stem cell have been the main focus of healing therapy research
For healing after a heart attack, the ideal time to administer these therapies is when reopening the clogged blood vessel
While stem cells show promise for heart attack treatment, the process of harvesting and reintroducing the cells
Heart attacks occur when the heart's blood vessel is blocked and blood flow stops, cutting off oxygen to the heart.
and tested the microspheres'effectiveness in pigs with induced heart attacks. The researchers observed that the microspheres were not toxic
It also did not decrease the size of the area damaged by the heart attack or the composition of the scar.
the study shows that microsphere therapy can potentially be an"off-the-shelf and immediate alternative to stem cell therapy"for treating heart attacks and potentially other diseases s
and Australian chemists have figured out how to unboil egg whites an innovation that could dramatically reduce costs for cancer treatments, food production and other segments of the $160 billion global biotechnology industry,
Shear stress within thin, microfluidic films is applied to those tiny pieces, forcing them back into untangled,
For example, pharmaceutical companies currently create cancer antibodies in expensive hamster ovary cells that do not often misfold proteins.
and make cancer treatments more affordable. Industrial cheese makers farmers and others who use recombinant proteins could also achieve more bang for their buck.
#Lawrence Livermore technology could help detect diseases in commercial swine industry Agricultural officials who seek to detect diseases affecting the commercial swine industry may gain a new ally a biological detection system developed by Lawrence Livermore
A study by LLNL and Kansas State university scientists found that the Lawrence Livermore Microbial Detection Array (LLMDA) could help identify diseases in the commercial swine industry.
Many of the diseases affecting the commercial swine industry involve complex syndromes caused by multiple pathogens
New infectious diseases in animal food production systems can create enormous impacts that can affect domestic consumption and exports
as well as public health in the case of diseases that can move from animals to humans, the paper authors wrote.
Two examples of new diseases introduced into the swine industry include theinfluenza A virus subtype H1n1 and Porcine epidemic diarrhea virus.
Two other foreign diseases, African swine fever and classical swine fever, remain constant threats to the U s. industry. he best assurance for the timely identification of known and unknown threats is to employ techniques
Currently, polymerase chain reaction (PCR) assays represent one technology widely used for pathogen detection but typically only a handful of microorganisms can be identified in a single test.
Another method of detecting pathogens, DNA sequencing, greatly expands the number of microorganisms that can be identified,
and requires significant expertise. he LLMDA can identify co-infections from a single sample, said LLNL biologist Crystal Jaing,
The array also can identify co-infections faster and cheaper than DNA sequencing. In their paper, the authors noted that as the LLMDA technology cost decreases and throughput increases
it becomes feasible to look at microarrays as everyday tools for use in the diagnostic laboratory. he beauty of the LLMDA is that it lets you identify unknown diseases that the researcher isn looking for,
and polymicrobial. hese multiple bacteria and viruses end up in a disease syndrome. Wee looking at a complex situation
and we need the tools that can give us a comprehensive look at the disease factors involved.
oral fluid and tonsils from pigs that have co-infections of porcine reproductive and respiratory syndrome virus (PRRSV) and Porcine circovirus-2 (PCV-2). The LLMDA easily identified PRRSV and PCV-2,
Clostridium and Staphylococcus. he use of the microarray technology could help the U s. detect the emergence of foreign animal diseases at their outset to prevent major disease outbreaks,
and lead author and graduate student J. Sherry Wang applied their new molecular tools to 44 DNA samples with known cancer-related single-nucleotide variants.
The ability to accurately find mutations that are biomarkers for disease will help clinicians determine treatment paths for patients,
It may also help identify rare mutations and subtypes of infectious diseases as well as drug-resistant strains.
but mutations can leave the body vulnerable to disease, or even be the root cause.
The ability to accurately find rare single-nucleotide mutations is becoming increasingly important as scientists drill down into genomes to find biomarkers for early cancer detection. ee trying to solve the needle-in-a-haystack problem,
The needle youe looking for might be a cancer-mutation DNA or bacterial-pathogen DNA,
when there not as much cancer DNA floating around, he said
#A new kind of wood chip: collaboration could lead to biodegradable computer chips Portable electronics typically made of nonrenewable,
as a result of human exploitation and disease-related die offs, says Joshua Miller, Phd student in the Department of Biological sciences and lead author on the study. hus,
The team of researchers tested the therapeutic potential of these carbon nanoparticles by loading them with an anti-melanoma drug
Scientists also found that they can alter the infusion of the particles into melanoma cells by adjusting the polymer coatings.
It is a very versatile platform to treat melanoma, other kinds of cancers and other diseases.
which will eventually lead to innovative drug therapies for cancer and other diseases i
#Actuators that mimic ice plants Engineers developing moveable robot components may soon take advantage of a trick plants use.
where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses. otton is one of the most fascinating and misunderstood materials,
which could help in warding colds, flu and other diseases. Two of Hinestroza students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Malaria kills more than 600,000 people annually in Africa. While insecticide-treated nets are common in African homes
Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics like catheters in the human body.
However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration.
Now, researchers at MIT Koch Institute for Integrative Cancer Research and Massachusetts General Hospital (MGH) have created a polymer gel that overcomes this safety concern
as there is a greater risk for fracture if a device is too large or too complex.
The researchers also say that single-administration delivery systems for the radical treatment of malaria
and other infections could significantly benefit from these technologies. Source: MIT, written by Kevin Leonard e
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