Liver diseases

Hepatitis (57)
Liver disease (31)

Synopsis: Domenii: Health: Health generale: Illness: Gastrointestinal diseases: Liver diseases:


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They then grew a pure culture of this single organism in the lab. An early guess is that this particular microbe may be linked to obesity and fatty liver disease


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The company is currently studying the device for treating Hepatitis C with patients on chronic dialysis,


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a mysterious type of equine hepatitis that is linked to blood products and causes liver failure in up to 90%of afflicted animals.

which eight horses had developed suddenly hepatitis after being injected with an antitoxin to prevent them from developing botulism.

and one later showed rising levels of liver enzymes that suggested liver disease. Although the researchers did not purify the virus before injecting it into the horses, Pablo Murcia, a virologist from the University of Glasgow,

After all, human hepatitis can be caused by at least five viruses. TDAV belongs to the family Flaviviridae,

dengue fever and hepatitis C. It is associated most closely with a genus of newly discovered viruses called Pegivirus,


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which is used to treat hepatitis. The law enforcement has to ship it by express mail to a lab that then has to process the drug and run a series of tests.


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This could help diagnose viruses like hepatitis C which people often don know they have u


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also known as subunit vaccines, have been successful against a few diseases, such as hepatitis and diphtheria. To develop subunit vaccines for other diseases,


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Upon autopsytheir fatty liver disease resembled that of an alcoholic. However the culprit was excess sugar


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In addition to diabetes, the researchers also think that interfering with pyruvate transport may help patients with nonalcoholic fatty liver disease, a condition common in people with obesity y


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300,000 cases of hepatitis C and 35,000 new cases of HIV each year, as well as other infections. t was one of the proudest days in my life,


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a drug used to treat hepatitis C, while other individuals did not. A side effect of ribavirin is that it causes anemia--a condition characterized by a decrease in red blood cell levels--in approximately 8 to 10 percent of patients."


R_www.nanomagazine.co.uk_category&id=172&Itemid=158 2015 00228.txt.txt

hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials & Interfaces.


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targeting lymphoma and a form of autoimmune hepatitis.""The spherical nucleic acids always win from potency and speed standpoints,

This observation has significant implications for treating liver cancer and cirrhosis patients.""The beauty of the approach is that a very small amount of drug does a tremendous amount of work,


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hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials


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for example, can show up cirrhosis. It is more difficult to measure the elasticity of the brain.


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What's more, they have demonstrated the practicality of this approach by identifying a novel molecule that blocks a key enzyme used by the hepatitis C virus."Our dream is to provide a do-it-yourself method--one that can be applied by anyone,


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Hepatitis C, and influenza using a strategy called lethal mutagenesis. This strategy seeks to extinguish viruses by forcing their already high mutation rates above an intolerable threshold.


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and hepatitis C. What they have in common is that the genome does not consist of DNA, but RNA.


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Interferon infection-fighting power is accompanied by severe side effects most commonly associated with its former use as a treatment for Hepatitis C that include, not surprisingly,


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Of all major organs, the liver has the highest capacity to regenerate that why many liver diseases,

including cirrhosis and hepatitis, can often be cured by transplanting a piece of liver from a healthy donor.

leading the researchers to conclude that these cells don contribute to liver cancer caused by obesity-induced hepatitis


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the researchers successfully used their sequencing kit to detect Hepatitis C in the blood of an infected UCSF patient,


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#Immune cells in liver drive fatty liver disease, liver cancer Fatty liver disease--alongside fatty liver due to massive alcohol consumption--is caused mainly by excessive consumption of fat

This is referred to as nonalcoholic fatty liver disease (NAFLD. If NAFLD becomes chronic--e g. through the constant uptake of high lipids

This can lead to nonalcoholic steatohepatitis (NASH)--a liver disease with clear detectable pathologic alteratons of the tissue.

These liver diseases (NAFLD and NASH) along with chronic viral infections are the most common causes of liver cancer or hepatocellular carcinoma (HCC.

T cells involved in the development of fatty liver disease NASH and HCC The mechanisms that cause diseases such as fatty liver disease steatohepatitis and HCC are still not widely understood.

However immune cells particularly CD8+T cells and NK T cells seem to play an important role.

Our results provide completely new insights into the development of these serious liver diseases. Building on this knowledge we now want to develop new preventive


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and develop fatty liver disease and abnormal blood lipid levels. All of these increase the risk of developing diabetes and cardiovascular disease.

and animals FGF21 levels are elevated in association with obesity insulin resistance and nonalcoholic fatty liver disease.


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including HIV and hepatitis C. The method, called Virscan, is an efficient alternative to existing diagnostics that test for specific viruses one at a time.


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hepatitis Researchers have developed a highly sensitive nanomechanical sensor that can detect cancerous tumours as well as viral disease markers for HIV,

hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.

including HIV, hepatitis, herpes, and many others. The sensor will also enable doctors to identify tumour markers,


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hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.

including HIV, hepatitis, herpes, and many others. The sensor will also enable doctors to identify tumour markers,

hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.

including HIV, hepatitis, herpes, and many others. The sensor will also enable doctors to identify tumour markers,


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including HIV, hepatitis, herpes, and many others. The sensor will enable doctors to identify tumor markers,


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For example, primary biliary cirrhosis (PBC) has been reported, controversially, to arise from viral infection, so it would be great to compare the virome of PBC patients with those without the disease.


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a life sciences and healthcare industry consultant, told GEN. Express Scripts is hoping to repeat the success it enjoyed last year in hepatitis C. In December 2014,

the company immediately added Abbvie Viekira Pak to its National Preferred Formulary as the exclusive option for patients with genotype 1 hepatitis Cust three days after the FDA approved the drug.

and only covers Sovaldi for non-genotype 1 hepatitis C. ur clients will save more than $1 billion this year on hepatitis C medications,

000-a-pill pricing by noting that the cost of Sovaldi is lower than the cost of complications associated with hepatitis C treatment, such as liver damage or liver failure.


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the group ran the scan on people known to be infected with hepatitis C and HIV.

Hepatitis C, Kula said, is detected often not for months or years, because few people think to ask about it.


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May 6th, 2015improving Clinical Care and Patient Quality of life in Advanced Liver disease, d-LIVER Workshop, Milan, 27 may 2015 May 6th, 201 0


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including Hepatitis C, SARS or MERS, could also benefit from the user friendly chip and its rapid results. is award is truly helping our lab become translational,


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including HIV, hepatitis, herpes, and many others. The sensor will enable doctors to identify tumor markers,


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"A lot of people have hepatitis C, for example, without realising,"says Elledge. You could imagine routinely screening people in this way,


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together with HIV and hepatitis C. The method is an efficient substitute to diagnostics available at present.


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#More clues to how drug reverses obesity diabetes fatty liver disease In addition to illuminating how the drug amlexanox reverses obesity diabetes

and fatty liver disease the findings suggest a new pathway for future treatments. The research was published Jan 12 in Nature Communications.


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This combination results in multiple health risks including high blood sugar and fatty liver disease. For years to gain insight into this phenomenon researchers focused on the role of altered insulin action in the liver in the production of triglycerides.

but instead reduces fatty liver disease in patients with type 2 diabetes. These results provide new insights into the pathogenesis of nonalcoholic liver disease

and provides new approaches to treat fatty liver disease which is now the most common liver disease in the world said Shulman.

Shulman and his team plan to apply similar methodology to translate their findings to insulin-resistant patients with type 2 diabetes hyperlipidemia and fatty liver disease e


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#'Crispr'science: Newer genome editing tool shows promise in engineering human stem cells In a recent online report on the work in Molecular Therapy the Johns Hopkins team says the findings could streamline

and speed efforts to modify and tailor human-induced pluripotent stem cells (ipscs) for use as treatments

SERPINA1 a gene that when mutated causes alpha1-antitrypsin deficiency an inherited disorder that may cause lung and liver disease;


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including HIV and hepatitis C."It turns out that it works really well,""Elledge says."


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We found that it significantly reduced inflammation in the fat tissues and improved kidney and liver disease.

"Our ultimate hope would be to use these findings to create a lipoxin-based drug for obese people to help protect them against associated illnesses, such as kidney and liver disease,


www.sciencedaily.com 2015 08888.txt.txt

Interferons are used, for example, in the immunotherapy of often refractory chronic viral infections such as hepatitis. The researchers postulate that the innovative mechanism in which two components of the innate immune system collaborate effectively in the epithelial cells may have developed in the course of evolution as a secondary line of immune defense in an environment in


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#Risk of hepatitis E outbreak'very high'in earthquake-ravaged Nepal During the coming monsoon season, survivors of the recent earthquake that destroyed parts of Nepal face a"very high

"risk of a hepatitis E outbreak that could be especially deadly to pregnant women, according to a consensus statement from a group of infectious disease experts from around the world.

There are an estimated 20 million hepatitis E infections in the world annually. While the virus can lead to liver disease,

it mostly runs its course with few long-term complications. Yet pregnant women have a mortality rate of 25 percent

"Hepatitis E is neglected a virus that isn't well understood but we are now seeing that it is likely a major cause of maternal deaths in countries where it is common,


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#Gel that can make drugs last longer A drug-delivering hydrogel has been developed to treat chronic diseases such as hepatitis C a liver disease that kills around 500,000 people worldwide every year.

Researchers at the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have developed a drug-delivering hydrogel to treat chronic diseases such as hepatitis C a liver disease that kills around 500,000 people worldwide every year."

and well-being of patients suffering from chronic diseases such as hepatitis C,"said IBN Executive director Professor Jackie Y. Ying.

The standard treatment for chronic hepatitis C infections includes a weekly injection of a protein drug called PEGYLATED interferon.

"Our hydrogels can significantly extend the half-life of hepatitis C drugs by up to 10 times longer than current treatment.

Up to 150 million people globally suffer from chronic hepatitis C infections according to the World health organization.""I believe that our method can pave the way for more effective and safe treatment of hepatitis C. We are also testing the microstructured gel for the treatment of other chronic diseases besides hepatitis C,"added Dr Kurisawa.

Story Source: The above post is reprinted from materials provided by The Agency for Science, Technology and Research (A*STAR.


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Other single-stranded RNA VIRUSES include the hepatitis C virus HIV and the winter vomiting bug norovirus.


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For example, the investigators teamed with Fabio Cominelli, MD, Phd, a Case Western Reserve Professor and Chief of the Division of Gastroenterology and Liver disease,


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and herpes and hepatitis C viruses. But for the class of viruses known as nonsegmented negative-strand RNA VIRUSES,


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including Hepatitis C, SARS or MERS, could also benefit from the user friendly chip and its rapid results. is award is truly helping our lab become translational,


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