Synopsis: Domenii: Transport:


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will pave the way for the development of restorative therapies for thousands of patients. Dr Davinia Fernández-Espejo


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Rice bioengineer David Zhang and his colleagues have developed a unique way to adjust their nucleic acid probe reagents on the fly

and effectively get them out of the way. This time the lab is developing synthetic DNA"protectors"that mimic the target sequence


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Park and his colleagues found a way to enhance thermal emission of hot bodies at the lower end of the spectrum (around 1 THZ) by manipulating the surface of the object.

holes or grooves--changes the way that electromagnetic radiation interacts with the surface. In some instances the geometry supports the formation of a wave of rippling electronic charges,

The results will also help the team calculate how rectenna thermal energy harvesting might compare to other ways of harvesting waste heat,

as well as ways to optimize large arrays of rectennas. Presentation EM+AS+SS-Mom6,"Metamaterial Enhanced Rectenna for Efficient Energy harvesting,"is at 10:00 a m. on Monday, Oct 19.


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Scientists at the IBS Center for Genome Engineering in South korea have created a way to genetically modify plants using CRISPR-Cas9 without the addition of DNA.

which Jin-Soo Kim points out,"paves the way for the widespread use of RNA-guided genome editing in plant biotechnology and agriculture."


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this new finding could pave the way for new treatments in the future, according to the study authors.

which could transform the way in which neurological diseases such as Parkinson's are understood and treated.''Claire Bale, Head of Research Communications at Parkinson's UK, said:'


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seizure disorders and many other conditions affecting the brain and nervous system down the road.""Using nasal mucosal grafting,

they use adjacent nasal lining to rebuild the hole in a permanent and safe way.


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Now scientists from The Langevin Institute, Paris, France, have constructed a new fingerprint imaging system that peers inside the finger to take a picture--a more reliable and secure way of identifying individuals.


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#New research paves the way to begin developing a computer you can control with your mind A team of researchers led by Angelika Lingnau, from the Department of psychology at Royal Holloway,


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"Currently, there's no easy way to do that.""One important aspect of the success of the new phototransistors is the researchers'innovative"flip-transfer"fabrication method, in


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The discovery of magnetoresistance paved the way for magnetic field sensors used in hard disk drives and other devices,


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Imsane does this in a completely general way, even for surfaces of complicated shape that change in time.

"By mapping it to the plane we were able to follow cells in a heartbeat,


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They investigated cell lines to determine the role played by VRAC and its subunits in the transport of cisplatin and carboplatin into the cell.

Without these two subunits, only little active substance finds its way into the cell. From the researchers'point of view, this goes some way into explaining why some people are resistant to some forms of cancer therapy.

In their experiments, the work group of Thomas Jentsch had switched systematically off different combinations of VRAC forming proteins.

Apparently, the VRAC subunit LRRC8D is immensely important for the transport of the amino acid taurine,


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--which would lead the way for growing micro-organs from scratch within the lab


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#DNA in blood can track cancer development, response in real time Scientists have shown for the first time that tumour DNA shed into the bloodstream can be used to track cancers in real time as they evolve

The findings could change the way we monitor patients, and may be especially important for people with cancers that are difficult to reach,


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"One of the group's key findings is that"by manipulating the shape of the wave that we use for levitation in specific ways,

and surgical centers as a way to immediately detect and characterize cancer or other diseases."


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Find a different way of looking and novel forms of life appear everywhere. A team of microbiologists based at the University of California, Berkeley, recently figured out one such new way of detecting life.

At a stroke, their work expanded the number of known typesr phylaf bacteria by nearly 50 percent,

After a point, discovery came to hinge on finding new ways of searching. e used to think there were just plants

Of course, no sooner do we think wee seen everything than we come up with a new way to see.

and he thinks it likely that growth will occur in surprising ways. ooking at things from a different angle may offer that possibility of a fourth domain,


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Each passage modifies the sound in a subtly different way as it travels towards the centreoughly


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And, the OSCS identification strategy may provide an alternative way to control heparin quality. Biosensors experts are enthusiastic about the sensor.


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Many parts of the brain are organized in obvious ways: in the motor cortex, for example, stimulating a particular spot causes motion in a specific part of the body.


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however, the only way to link up to a robotic arm is directly through the brain by way of an implant.


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The project run by CITIES Foundation recently launched their pilot scheme in Amsterdam Noord. WASTED is a three-part system

which include free beers, discounts on groceries and 50 percent off of bike repairs. Individuals, collectives and schools can also take advantage of a free educational package

What other forms of waste can also be reused in educational, community-building ways y


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#Smart mirrors in fitting rooms show heat in action Savvy retailers are increasingly utilizing smart technology to enhance their customersinstore experience.


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but it definitely never hailed a cab. Oh, and back to the portability issue. Don fret,


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The company says it conducted several tests in reputable labs to determine the best way to deliver good performance

The company decided crowdfunding was the way to go due to the platform reach. Besides the validation (and money) a successful campaign brings,


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but the powertrain system, which includes the engine, also accounts for a large proportion of the vehicle weight.

and manager of the research area Lightweight Powertrain Design at the Fraunhofer Project Group for new drive systems. he cylinder casing weighs around 20 percent less than the equivalent aluminum component,


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and he believes PBS-1086 as a shotto play a similar role in NSCLC. he NF-KAPPA-B pathway is engaged by cells in response to EGFR inhibitors as a way to survive treatment,


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however, been a good way to find out exactly what each one does. An enhancer might affect a gene next door or several genes across the genomer maybe none at all.


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Singapore (NTU Singapore) scientists have found a new way to treat dementia by sending electrical impulses to specific areas of the brain to enhance the growth of new brain cells.

and this breakthrough could pave the way towards improved treatments for patients. Growing new brain cells For decades, scientists have been finding ways to generate brain cells to boost memory and learning,

but more importantly, to also treat brain trauma and injury, and age-related diseases such as dementia. As part of a natural cycle, brain cells constantly die


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and new biological ways to identify and stratify the ASD population into clinical sub-types


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the artificial intelligence pioneers saw that graphics programs would soon be able to synthesize realistic images by calculating the way in


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and by the differences in the way the trends have played out at the state level.


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#New Way to Fight Cancer Targeted cancer therapies work by blocking a single oncogenic pathway to halt tumor growth.

these novel findings suggest a promising new way to fight cancerarticularly cancers that are aggressive


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#Computer-Designed Rocker Protein Worlds First To Biomimic Ion Transport For the first time, scientists recreated the biological function of substrate transportation across the cell membranes by computationally designing a transporter protein.

and cell signaling, for instance, between nerve cells in the brain and spinal cord. o our knowledge, this is the first transport protein designed from scratch that is,

and protons can flow in a controlled way across the lipid-membrane barrier around the cell-like vesicle.

and the engineered system works like natural transport proteins found throughout the human body. Rocker was designed to perform this function by doing one thing ockingbetween two different shapes, or conformations.

Like a gatekeeper, the engineered transport protein controls what moves in and out of the cell from one side of the membrane to the other. ill Degrado and his postdoc

Nathan Joh, hypothesized that the complex transportation function could be generated through engineering of this simple ockingmotion,

mechanisms and interactions of known transporters to overcome several barriers in protein engineering, including membrane protein folding.

I like to use enhanced sampling techniques to more fully capture the entire transport process using Stampede resources,

making sure that the transporter that youe made ends up in the right place at the right time.


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Goosby said the findings show the need for interventions. iguring out ways to intervene and help young people to be resilient in the face in these kinds of challenges is said key,


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That the way to attack it. The methodology has been validated with known electrolytes. Using the supercomputers at Berkeley Lab National Energy Research Scientific Computing Center (NERSC),


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meaning that all the cells in the culture are quite similar to each other in the way they express their genetic information. reviously,


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the technology enables swarms of compact UAVS to take off from ships, tactical vehicles, aircraft or other unmanned platforms.

Another technology demonstration of nine UAVS accomplished completely autonomous UAV synchronization and formation flight. ONR officials note that

able to step in and take control as desired. his level of autonomous swarming flight has never been done before,

and reconfigurable will manned free aircraft and traditional weapon systems to do more, and essentially multiply combat power at decreased risk to the warfighter.

Even hundreds of small autonomous UAVS cost less than a single tactical aircraft and officials note, having this capability will force adversaries to focus on UAV swarm response.


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one that could lead to a way to address the problem and prevent cancer relapse.

and first author Lee B. Rivera, Phd, a UCSF postdoctoral scholar in the Bergers laboratory, also identified a potential way to stop myeloid cells from sabotaging the therapy

Bergers noted that the discovery potentially gives physicians a way to determine how effective anti-VEGF therapy might be in individual patients


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#Protein finding can pave the way for improved treatment of malignant melanoma Researchers from Aarhus University have linked for the first time a new protein with malignant melanomas.


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and oil industry in that we can produce chemicals and fuels in a totally renewable way, rather than extracting them from deep below the ground.


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which stands for cytometry by time-of-flight, and it gives researchers greater insight into the intricacies of immune cells than ever before.


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Department of energy Conversion and storage (DTU Energy) has discovered a new way to stabilize an ion conducting material with a 100 times faster ion conductivity than all previous known ion conductors. he new

and our knowledge in ionic and electronic transport mechanism in these films says Professor Nini Pryds.

What we know is that they have gained a new way to access the best ion conductor available.

and new exciting way to use the unlocked forbidden material n


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#Expanding the reach of metallic glass Metallic glass, a class of materials that offers both pliability and strength, is poised for a friendly takeover of the chemical landscape.


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The Hands Omni glove developed at Rice Oshman Engineering Design Kitchen will provide a way for gamers


R_www.technology.org 2015 00002700.txt

he discovery that TMPRSS2 drives cancer pain demonstrates another way that cancers lead to suffering.


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and we don have a very good way to stop that, he says. s we turn to the future possibility of transplanting human stem cells in place of islets,


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or graphene, nanoengineers at the University of California, San diego have invented a new way of fabricating nanostructures that contain well-defined, atomic-sized gaps.

This is the only way so far in which we can place single-layer graphene between two metals

In the future, the team would also like to explore ways to vary the thickness of the well-defined gap between the structures by increasing the number of graphene layers. or optical applications,


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The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.

These symptoms include airway narrowing, airway twitchiness and inflammation all of which contribute to increased breathing difficulty. ur findings are said incredibly exciting

from the School of Biosciences. or the first time we have found a link airways inflammation,

cigarette smoke and car fumes and airways twitchiness in allergic asthma. ur paper shows how these triggers release chemicals that activate Casr in airway tissue

and drive asthma symptoms like airway twitchiness, inflammation, and narrowing. Using calcilytics, nebulized directly into the lungs,

the identification of Casr in airway tissue means that the potential for treatment of other inflammatory lung diseases beyond asthma is immense.

the Cardiff Partnership Fund and a BBSRC parking Impactaward d


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#Transparent Armor based on Spinel Could Also Ruggedize Your Smart Phone Imagine a glass window that tough like armor,

NRL invented a new way of making transparent spinel, using a hot press, called sintering.

onformal with the surface of an airplane or UAV wing, depending on the shape of the press.

o we can make near net shape product that way. NRL was not the first to try sintering.

is what the best way to do that? For both the Department of defense (Dod) and private industry, ost is a big driver,

The military also interested in using spinel to better protect visible and infrared cameras on planes and other platforms.

His lab also makes lightweight, inexpensive fibers for infrared countermeasures applications on helicopters and other platforms.


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#Perseverance paves way for wind laser Developing new satellite instruments is always challenging, but at times more head-scratching is needed to create something truly cutting-edge.

ESA Aeolus mission may have caused a few headaches along the way, but its wind lasers are now ready

and laser technology for some time and encountered some pitfalls along the way. evertheless, we have overcome these with a mixture of technical solutions.

he delivery of the second flight laser is a major achievement by Selex-ES, who have overcome major technology issues along the way. he contributions of Airbus Defence and Space,

who have remained closely involved with Selex-ES throughout, as well as the valuable support the Aeolus project has had from the engineers in ESA


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In this way they influence the orientation of the spindle apparatus and control the spatial arrangement of the new cells. s in a GPS SYSTEM


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known as a nanoelectromechanical system (NEMS) resonator. ne standard way to tell the difference between molecules is to weigh them using a technique called mass spectrometry.

The way the frequencies change depends on the mass and shape of the molecule so we can now tell a lot about how it looks

A common way to decipher molecular structures is to use x-ray crystallography. This complicated method involves purifying and crystallising the molecules


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The UT-researchers however found a simple and efficient way to actively use scattered light to improve the resolution of images.


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however, the hydrogels currently available for tissue regeneration of the musculoskeletal system couldn meet the mechanical and biological requirements for successful outcomes. ur international biofabrication research team has found a way to reinforce these soft hydrogels via a 3d printed scaffold structure


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shortly called STAMP, relies on a property of light called dispersion that can be observed in the way a misty sky splits sunshine into a rainbow of colours.

Nakagawa notes that STAMP operates on the assumption that all the differently coloured daughter pulses interact with the imaged object in the same way.

and will find ways to develop it further and discover something new. In a way, it is technology that can make time slow down.


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Migration along a gradient, called a taxis, is found all over nature. The daily vertical migration of marine plankton toward sunlight, is one example,

and it the way many microbes find food. f you can design particles that can feel their environment


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affiliated with the University of Montreal, have identified a way to use a an openerto force the virus to open up

Furthermore, this discovery opens the way for the development of strategies to eliminate the viral reservoirs of individuals already infected.


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is due to be deployed in fiscal year 2016. ee integrating a lot of new and different ways of doing things into this diagnostic,


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Scientists at the U s. Department of energy (DOE) Argonne National Laboratory have created a new way of manipulating high-intensity X-rays,

but ultimately promising new ways to steer, filter, and shape X-ray pulses as well, said Stephen Streiffer,

a professor of materials science at the University of Wisconsin-Madison. hey have found a way to significantly shrink the optics,

he said. he advantage of this new device is that it provides a very cheap way to generate


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but we want to find ways to make CNT alignment even straighter, Zhu says. t still not perfect. n addition,


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There no way around this until a reliable method for cleaning the electronics is developed says Brunner.


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The MIT researchers tested their system on an autonomous underwater glider, and demonstrated that the robot was able to operate safely among a number of other autonomous vehicles,

The glider, using the system, was able to adapt its mission plan to avoid getting in the way of other vehicles,

while still achieving its most important scientific objectives. If another vehicle was taking longer than expected to explore a particular area,

the glider, using the MIT system, would reshuffle its priorities, and choose to stay in its current location longer,

Just as a hierarchical crew runs the fictional starship Williamsenterprise system incorporates levels of decision-makers. For instance, one component of the system acts as a aptain, making higher-level decisions to plan out the overall mission,

Another component functions as a avigator, planning out a route to meet mission goals. The last component works as a octor,

and doesn collide with anything along the way. So it has the ability to adapt to its environment.

This technology can offer a whole new way to observe the ocean, which is exciting


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In this way, the temperature is reduced and some of the aggressive substances can be removed before the measurements are performed.

The way forward The shipping company A p. Møller-Maersk has tested the prototype in practice. Marine Engineer Per Hother Rasmussen says:


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Researchers may have discovered first gene delivery system that efficiently penetrates the hard-to-breach human airway mucus barrier of lung tissue.

and Federal University of Rio de janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue proving the concept,

asthma and other life-threatening lung diseases. o our knowledge, this is the first biodegradable gene delivery system that efficiently penetrates the human airway mucus barrier of lung tissue,

inhaled matter is trapped typically in airway mucus and subsequently swept away from the lungs via beating activities of cilia,

His team experiments with human airway mucus and small animals, Suk adds, were designed as a proof-of-concept study demonstrating that placing corrective

but it also makes the airway mucus harder to overcome by inhaled therapeutic nanoparticles. Most of the existing drugs for CF help clear infections but do not solve the disease underlying problems.

in this case the mucus covering the lung airways. In other words, conventional nanoparticles are too sticky to avoid unwanted off-target interactions during their journey toward the target cells.

rendering them too large to penetrate the mesh of airway mucus. For its design, the team developed a simple method to densely coat the nanoparticles with a nonsticky polymer called PEG,

and are capable of rapidly penetrating human airway mucus freshly collected from patients visiting the Johns Hopkins Adult Cystic fibrosis Program directed by Michael Boyle,


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#Small tilt in magnets makes them viable memory chips UC Berkeley researchers have discovered a new way to switch the polarization of nanomagnets,

paving the way for high-density storage to move from hard disks onto integrated circuits. This image taken from a computer simulation shows nanomagnets tilted at various angles,


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with these particles attaching to each other in ways that produce chaotic or inflexible configurations. The NYU team developed a new method to apply DNA coating to colloids

Specifically, it employed a synthetic strategylick chemistryntroduced more than a decade ago that is a highly efficient way of attaching DNA.


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suggests people modify language in this way because it makes things simpler for our minds as speakers, listeners,


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such as common E coli, to produce valuable chemical commodities in an environmentally friendly way. By leveraging their natural metabolic processes,

In this way they can be thought of as the medium for two-way communication between humans and cells.

or toxins and could unlock new fundamental insights into metabolic pathways. ur team is developing several different ways to make even more custom biosensors,

and we need new ways to get our hands in at the molecular level wee now reaching in deeper than wee previously been able to,


R_www.technology.org 2015 11468.txt.txt

any way you want me: Scientists curve nanoparticle sheets into complex forms Scientists have been making nanoparticles for more than two decades in two-dimensional sheets, three-dimensional crystals and random clusters.

Now researchers from the University of Chicago, the University of Missouri and the U s. Department of energy Argonne National Laboratory have found a simple way to do exactly that.

The findings open the way for scientists to design membranes with tunable electrical, magnetic and mechanical properties that could be used in electronics

so they end up distributing themselves in a nonuniform way across the top and bottom layers of the nanoparticle sheet.

came up with an ingenious way to measure the molecular asymmetry, which at only six angstroms,


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however, is good reconnaissance a reliable way to obtain real-time data about how well a particular therapy is working for any given patient.


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and development of tumors a discovery that could lead to new ways to diagnose and treat cancer.

The discovery may also lead to new ways to diagnose and treat brain cancer, such as gliomas, medulloblastomas, and neuroblastomas;

a company co-founded by Garner to develop new ways to assess cancer risk, create diagnostics,


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Moreover, the discovery paves the way for further studies on the significance of caveolae for cancer


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to create and maintain a superfluid gas long enough to observe it at ultrahigh synthetic magnetic fields. oing to extremes is the way to make discoveries,

During that time, the team took time-of-flight pictures of the distribution of atoms to capture the topology


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#Scientists find a new way to manufacture graphene nanoribbons for future electronics There is no doubt that graphene is the key to the future of electronics.

But now scientists found a way to manufacture ultra-narrow nanoribbons with smooth straight edges directly on germanium wafers.

it is hard to explain it in a commonly understandable way. Graphene is only one atom thick material,

So now scientists will try to find a way to control the place where graphene starts growing


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Researchers have discovered a way to trigger a preventive response to a flu infection without any help from the usual players the virus itself or interferon, a powerful infection fighter.

The finding, in both mouse and human cells, suggests that manipulating a natural process could someday be an alternative way to not just reduce the severity of the flu,

But the way it targets the virus by trapping it and disabling its ability to make copies of itself means that increasing the protein level before the flu ever arrives would prevent infection from occurring.

flu-like symptoms. e figured out a way to induce just this single interferon response the most important thing interferon does for flu,


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Hubbard has developed a way to reduce the off-target DNA binding of a class of gene editing proteins known as transcription activator-like effector nucleases (TALENS).


R_www.technology.org 2015 11858.txt.txt

a breakthrough that heralds a faster and potentially less expensive way to produce many different types of plant-based medicines.

Smolke said. e need options to help ensure that the bio-based production of medicinal compounds is developed in the most responsible way. molke said that in the United states,


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and destabilize the glacier in a number of ways: The water can speed the glacier flow downhill toward the sea;

they discovered that the seismic vibrations being detected by the equipment was caused by meltwater percolating down through the glacier and weaving its way through the complicated plumbing system in the interior of the ice.


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it gets in the way, he said. In the new studies, the team demonstrated that mice missing the factor that clears fibrin had impaired vascularization and bone union.


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many other research labs around the world are working on ways to use induced pluripotent stem cells (ipscs) to repopulate diseased livers

or chemical carcinogens. ybrid hepatocytes represent not only the most effective way to repair a diseased liver,

but also the safest way to prevent fatal liver failure by cell transplantation, Karin said p


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