Aiden, who is also a senior investigator at Rice Center for Theoretical Biological Physics, said the researchers found that a set of proteins acts like the plastic slider,
Nanotechnology, Biology and Medicine. While current HIV treatments involve pills that are taken daily, the new regimens'long-lasting effects suggest that HIV treatment could be administered perhaps once or twice per year.
a program director in NSF Division of Environmental Biology, said, abitat fragmentation has large effects,
Lead author Professor John Ladbury, Dean of the University of Leeds'Faculty of Biological sciences and Professor of Mechanistic Biology, said,
said lead author Mark Walker, Ph d. a Professor of Biological sciences at the University of Wollongong. n the case of the invasive strep clone,
whose first author is the quantitative biologist Ivan Iossifov, a Cold Spring Harbotr Laboratory assistant professor and on faculty at the New york Genome Center, finds that"autism genes"-i e.,
including a number of compounds with known biological activity. Bogyo and his associates focused on a compound called ebselen because,
Finally the team had to prove that the electronic signal could be recognized by a biological neuron.
There are six types of biological sensing mechanisms in the human hand and the experiment described in Science reports success in just one of them.
"says the molecular biologist Prof. Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn.
They say that ultra-low-power communication systems in wearable devices will transmit signals of much less power than things like MRI SCANNERS and wireless implant devices, with magnetic fields passing freely and harmlessly through biological tissue.
At its current dimensions, it can be draped over very small objects the size of a few biological cells (1, 300 square microns in area),
"said Percival Zhang, a professor in the Department of Biological Systems Engineering, which is in both the College of Agriculture and Life sciences and the College of Engineering.
Typically in biological conversions, these two sugars can only be used sequentially, not simultaneously which adds time and money to the process.
is published in leading scientific journal PLOS Biology on Wednesday 8 april. The research indicates that drug treatments with two antibiotics can be designed to kill bacteria at dosages that would ordinarily cause rapid development of drug resistance and sustained bacterial growth,
#Biologists identify brain tumor weakness The study, led by researchers from the Whitehead Institute and MIT's Koch Institute for Integrative Cancer Research, found that a subset of glioblastoma tumor cells is dependent on a particular enzyme that breaks down the amino acid glycine.
a professor of biology at MIT and member of the Whitehead Institute, is the paper's senior author.
Matthew Vander Heiden, the Eisen and Chang Career development Associate professor of Biology and a member of the Koch Institute, also contributed to the research,
is a key mediator of oxidative damage and cell death in biological systems. The way cell death occurs
appear in the current issue of ACS Chemical Biology.""These are reported the first small-molecule Hur inhibitors that competitively disrupt Hur-RNA binding
and involved the collaboration of chemists, cancer biologists, computer modeling experts, biochemists and biophysicists at KU--notably the labs of Xu, Jeffrey Aub in the Department of Medicinal Chemistry and Jon Tunge in the Department of chemistry.
The International space station is an international science laboratory in low Earth orbit where astronauts conduct scientific research in biology, human biology, astronomy, meteorology and other fields in a gravity-free environment.
"said Renny Franceschi, U-M professor of dentistry, biological chemistry and biomedical engineering. Franceschi and colleagues recently discovered a biomarker that they believe achieves this differentiation.
"says Cesar Castro, MD, of the MGH Cancer Center and Center for Systems Biology, co-lead author of the report."
"The emerging genomic and biological data for various cancers, which can be essential to choosing the most appropriate therapy,
"says Ralph Weissleder, MD, Phd, director of the MGH Center for Systems Biology (CSB) and co-senior author of the paper."
Tokmakoff's biological research involves proteins, not DNA. But together their research teams were able to fruitfully undertake one of the first 2d infrared spectroscopic studies of the therapeutic mechanism of an antiviral drug."
"Our system represents an emerging alliance between the fields of materials sciences and biology, where opportunities to make new functional devices can mix
a senior co-author and professor of biological psychiatry at the University of Oslo in Norway."
however, are far greater as they can help explaining the biological mechanisms of widespread human diseases involving altered immune and inflammatory responses.
As part of the precision medicine initiative at the Cancer Institute of New jersey, investigators--which include colleagues from Rutgers Robert Wood Johnson Medical school and RUCDR Infinite Biologics, the world's largest university-based biorepository,
and professor of anatomy and regenerative biology at the George washington University School of medicine and Health Sciences."
Prof Sader says this technique revolutionises molecule detection for biologists, or indeed anyone who wants to measure extremely small objects.
and inertial imaging could prove very useful for biological scientists.""You can imagine situations where you don't know exactly what you are looking for,
"Olga and her collaborators have demonstrated that extraordinary results can be achieved by merging deep biological insight with state-of-the-art computational methods,
and I believe we are still at the early stages of developing new ways to think about biological networks and their control,
The findings, described in the April 28 issue of the journal PLOS Biology, could lead to new approaches for helping people learn more efficiently.
and insights for developing additional therapeutic strategies in the future,"explained Ed Seto, Ph d.,senior member of the Cancer Biology and Evolution Program at Moffitt t
Three atom-thick layers of molybdenum disulfide were cooked up in the lab of Jiwoong Park, associate professor of chemistry and chemical biology and member of the Kavli Institute at Cornell for Nanoscale Science.
Biopharmaceuticals, or biologics, are produced proteins by living cells. Proteins such as catalase are tens of thousands of times larger than the small molecules that make up traditional drugs.
but it also exerts other biological effects, and it can be converted by arginase to alternative compounds that counteract its benefits to the circulation."
"says first author Matthew Doyle, Phd candidate in the School of Biological sciences.""Our results are very exciting#we are not just talking about one molecule in one particular pathogen but rather a building block
and processes which rely on coupling biological molecules to cell surfaces. The latest findings follow more than a decade of work led by Associate professor Renato Morona looking at how bacteria cause disease.
"We believe that these organoids are an important new tool in the arsenal of cancer biologists
based on biological information and performance in statistical analysis. Patients with pancreatic cancer were found to have increased levels of each of the three proteins
to realise a biological outcome, "Professor Wallace said.""This paves the way for the use of more sophisticated printers to create structures with much finer resolution."
In view of the presence of MOCOS in many organs and its involvement in numerous biological and neurobiological functions
while revealing new clinical and biological disturbances in these patients. This work therefore opens new pathways for research
"said lead author of the research, Dr Kevin Gonzales, Post Doctoral Fellow at the Stem Cell and Regenerative Biology at GIS."
"Co-lead author Research Fellow Dr Liang Hongqing at GIS'Stem Cell and Regenerative Biology added,
and atomic nuclei within molecules that take place in less than a tenth of a trillionth of a second--information that will benefit groundbreaking research in materials science, chemistry and biology.
and other biological tissues because of needle buckling or fracturing on penetration. A research team in the Department of Electrical and Electronic Information Engineering
which dissolves upon contact with biological tissue. Silk fibroin is used as the dissolvable film because it has high biocompatibility,
"The study links a family of enzymes--molecules that act as biological catalysts--known as polyketide synthases (PKS) directly to a complex series of chemical reactions that ultimately add sulfur to leinamycin, a member of the polyketide family of natural products."
"says Phd candidate Daniel Hunter from the UNSW School of Biological, Earth and Environmental sciences.""The devil is the obvious answer.
"Hunter is the lead author of a study published in the journal Biological Conservation, which highlights the potential benefits of using the devil as a replacement apex predator.
Chemistry & Biology. Making Leptin Last Longer Lerner's laboratory helped pioneer techniques for generating billions of different antibodies
"So using this method we can look at interactions between four biological components inside a cell in three-dimension and at very high resolution of about 10 nanometers,
#New embryo image processing technology could assist in IVF implantation success rates A collaboration between biologists
and quickly recreate microenvironments found across biology. To illustrate the potential of their technique, the Illinois team mixed breast cancer cells and cells called macrophages that signal cancer cells to spread
Arraykilian said his team's synthetic microenvironment lies somewhere in the middle of two extremes in the field of modeling biology:
then you can ask fundamental biological questions.""Kilian said these questions range from the basic--how macrophages signal to the breast cells--to the more long-term:
"Now, researchers can ask more sophisticated biological questions than they could, "Kilian said. And they can do it quickly.
and Argonne National Laboratory turned to biology. There are no naturally occurring proteins known to bind uranyl,
The findings, detailed online in Nature Chemical Biology on Aug 31, 2015 have widespread implications for a broad range of industrial, scientific and medical applications in
keeping the whole biological machine running smoothly. But in diseases such as breast cancer, the breakdown of this order has been associated with the rapid growth and spread of tumors."
as a tenet of modern biology held that only viruses and living microbes such as bacteria could transmit disease.
They presented their findings Aug 26 at the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society in Milan, Italy.
An advantage of this system is that magnetic fields are able to pass freely through biological tissues,
followed by thorough clinical, biochemical and molecular biological investigations, the researchers found the causative mutation
For a long time molecular biologists believed that RNA is a short-lived storage medium. DNA (deoxyribonucleic acid), the blueprint of every living thing, is transcribed into RNA,
The research will be published by the IEEE Engineering in Medicine and Biology Society, the world's largest society of biomedical engineers."
#New molecule found to prevent preterm birth Premature births are linked intimately with inflammation of the uterine tissue, a biological response
because we know they are predisposed strongly to have biological activity--antibiotic activity, antiviral activity, herbicidal activity,
chemical and biological functions of the protein in the human body, will speed up the drug discovery process
Vogel and her co-authors, SMU biologist John G. Wise, and doctoral candidates Courtney A. Follit and Frances K. Brewer, reported their findings in the journal Pharmacology Research & Perspectives.
chemical and biological functions of the protein in the human body, will speed up the drug discovery process
Vogel and her co-authors, SMU biologist John G. Wise, and doctoral candidates Courtney A. Follit and Frances K. Brewer, reported their findings in the journal Pharmacology Research & Perspectives.
By combining nanoscience and biology, researchers led by scientists at University of California, Berkeley, have taken a big step in that direction.
Yang said his hybrid inorganic/biological systems give researchers new tools to study photosynthesis --and learn its secrets."
By combining nanoscience and biology, researchers led by scientists at University of California, Berkeley, have taken a big step in that direction.
In a roundtable discussion on his recent breakthroughs and the future of synthetic photosynthesis, Yang said his hybrid inorganic/biological systems give researchers new tools to study photosynthesis
"It's essential that we continue to research basic biology to further understand how cells become cancerous.
and Wyss Institute Founding Director Donald Ingber, M d.,Ph d.,who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children's Hospital and Professor of Bioengineering
which was chosen as the Paper of the Week in the Journal of Biological Chemistry, the scientists created novel assays to more accurately measure the brain's energy production.
Hervé and Professor Keevil (Centre for Biological sciences, Faculty of Natural and Environmental sciences. The team that conducted the study now forms the basis of the University's Network for Antimicrobial Resistance and Infection Prevention (NAMRIP) Strategic Research Group,
from the Department of Biological sciences and Mechanobiology Institute at NUS, collaborated with researchers from the Yong Loo Lin School of medicine at NUS
by Professor Margit Burmeister of U-M. The research team looked at the biological roles of BNIP
who Is distinguished the Trustees Professor of Biological sciences at UD. The research, supported by the National institutes of health-National Institute of Child Health and Human Development and the Delaware INBRE program, is published in the Journal of Biological Chemistry.
It is one of the top most viewed articles published online this summer under the Membrane Biology affinity group, according to the editorial offices of the American Society for Biochemistry and Molecular biology.
Understanding what happens in the fertilization process takes a little walk down biological memory lane
a reminder of nature's course that led to most of us. Once the egg is released from an ovary
from the Department of Biological sciences and Mechanobiology Institute at NUS, collaborated with researchers from the Yong Loo Lin School of medicine at NUS
by Professor Margit Burmeister of U-M. The research team looked at the biological roles of BNIP
and virus biology that could translate into valuable therapeutic and diagnostic applications Dr Jonathan Loh,
Macdonald, a Canada Research Chair in Islet Biology, associate professor in the University of Alberta's Faculty of medicine & Dentistry and member of the Alberta Diabetes Institute, is the senior author of a landmark study in the Journal of Clinical Investigation.
and is the first time that scientists have reported the ability to create biological structures that are programmed readily to assemble
with a flick of a switch and a temperature jump, make a huge range of biological molecules that either assemble or disassemble."
and then go back to explore how biology is already making use of them
#Two-drug combination shows promise against one type of pancreatic cancer One form of pancreatic cancer has a new enemy:
#Physiologists uncover a new code at the heart of biology UT Southwestern physiologists trying to understand the genetic code have found a previously unknown code that helps explain which protein should be created to form a particular type of cell.
as the finding uncovers an important regulatory process that impacts all biology, "said Dr. Yi Liu, Professor of Physiology.
said Andrei Goga, MD, Phd, professor of cell and tissue biology, and of medicine at UCSF and a co-corresponding author on the new study."
--which a consortium of researchers at UCSF are applying to diverse biological and clinical questions--could have a major impact on the emerging field of precision medicine."
describe the unexpected biological features of this new system and demonstrate that it can be engineered to edit the genomes of human cells."
and their natural biological function was described initially in 2010 and 2011. The application of the CRISPR-Cas9 system for mammalian genome editing was reported first in 2013, by Zhang and separately by George Church at Harvard.
Now, researchers at DTU Systems Biology have combined genetics with computer science and created a new diagnostic technology based on advanced self learning computer algorithms
Associate professor Aron Eklund from DTU Systems Biology explains:""We are pleased very that we can now use the same sequencing data together with our new algorithms to provide a much faster diagnosis for cancer cases that are difficult to diagnose,
or replaced by modern techniques that give the physician an indication of the elasticity of a biological tissue.
Nanotechnology, Biology and Medicine. While current HIV treatments involve pills that are taken daily, the new regimens'long-lasting effects suggest that HIV treatment could be administered perhaps once or twice per year.
and works by analyzing an interference pattern created when a beam of light that travels through a biological sample,
A device that detects in saliva a biological indicator of a possible risk of TYPE II DIABETES is the development of a technological and scientific team of the Tec de Monterrey (Mexican University) in collaboration with the University of Houston.
and is applied now to biology.""While the idea is to make the patient's life easier,
"Ferritin, which is as close as biology has given us to a naturally magnetic protein nanoparticle,
Taking advantage of the layered structure of many biological specimens, Sebastian Streichan and Idse Heemskerk created the Image Surface Analysis Environment (Imsane),
"Often in biology, the action is curved on a surface of interest. Although the recording of the cube containing this surface is 2 TB,
"The program is especially useful for biologists who otherwise would have to acquire the skillset and hardware to handle large data
"In the near future, the group plans to apply their method to a wide range of biological materials,
they form a biological film over the titanium to protect themselves from antibiotics. Once the implant is colonized by germs,
Other biological molecules do not appear to interfere with the probe. Wei says the ethod could
says neuro biologist Howard Eichenbaum at Boston University in Massachusetts. But he cautions that mimicking it could be difficult
UC San francisco scientists identified a biological escape hatch that explains the resistance, and developed a strategy in mice for shutting it down.
Understanding the biological basis of acquired resistance has proved difficult, partly because patients with late-stage lung cancer rarely undergo surgery,
Assistant professor Ajai Vyas from NTU School of Biological sciences said he findings from the research clearly show the potential of enhancing the growth of brain cells using deep brain stimulation. round 60 per cent of patients do not respond to regular antidepressant treatments
#Biologists identify brain tumor weakness Biologists at MIT and the Whitehead Institute have discovered a vulnerability of brain cancer cells that could be exploited to develop more-effective drugs against brain tumors.
and new biological ways to identify and stratify the ASD population into clinical sub-types
#Computer-Designed Rocker Protein Worlds First To Biomimic Ion Transport For the first time, scientists recreated the biological function of substrate transportation across the cell membranes by computationally designing a transporter protein.
solar-powered green chemistry using sequestered carbon dioxide. ur system represents an emerging alliance between the fields of materials sciences and biology,
a research team, led by a UC San francisco biologist, has isolated energy-burning eigefat from adult humans,
said senior investigator Shingo Kajimura, Phd, UCSF assistant professor of cell and tissue biology, School of dentistry, with a joint appointment in the UCSF Diabetes Center and the Eli and Edythe Broad Center
with applications for everything from fuel cells to biological implants. t a huge step for nanofabrication, said Jan Schroers, professor of mechanical engineering and materials science at Yale,
Prof Sader says this technique revolutionises molecule detection for biologists or indeed anyone who wants to measure extremely small objects.
and inertial imaging could prove very useful for biological scientists. ou can imagine situations where you don know exactly what you are looking for,
The device collects trace fluid samples from a biological surface for electrochemical analysis to detect glucose,
La Belle is an assistant professor in the School of Biological and Health Systems Engineering, one of ASU Ira A. Fulton Schools of Engineering.
Many interesting and important structures in biological cells and computer chips have features smaller than that.
In the new method, the object you want to see for instance a biological cell is placed on the substrate of the scattering material
because they had excellent biological properties, however, the hydrogels currently available for tissue regeneration of the musculoskeletal system couldn meet the mechanical and biological requirements for successful outcomes. ur international biofabrication research team has found a way to reinforce these soft hydrogels via a 3d printed scaffold structure
so that their stiffness and elasticity are close to that of cartilage tissues. Professor Hutmacher said the team had introduced organised high-porosity microfiber networks that are printed using a new technique called elt electrospinning writing e found that the stiffness of the gel/scaffold composites increased synergistically up to 54 times,
can we design a particle that can sense its environment with no neural system or biological parts.
Researchers believe this new information on basic ovarian biology will help them better understand the cause of ovarian disorders,
DNA-loaded nanoparticles possess positive charge that caused them to adhere to negatively charged biological environments, in this case the mucus covering the lung airways.
Made of a biological component such as a fluorescent protein and a etectorthat responds to the presence of a specific chemical,
M d.,Ph d.,who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children Hospital,
and may even have implications for understanding biological systems. Working at the Center for Nanoscale Materials (CNM) and the Advanced Photon Source (APS), two DOE Office of Science User Facilities located at Argonne,
This research has just been published in the scientific journal Development at http://dev. biologists. org/Currently,
and biological species and photonic devices that manipulate light. Furthermore, this method of producing nanoribbons is complicated not overly it is scalable
a Phd student in chemistry and a member of Smolke team. heye the action heroes of biology. o get the yeast assembly line going,
Bone biology does not require fibrin to heal a fracture. Fibrin is involved in blood clotting; it forms a meshlike net that traps platelets to form a clot.
this range is observed comparable to that for other important biological hormones such as insulin. Furthermore, the investigators developed a protocol,
and gait patterns for the children over time, including some designs that a human designer would not have been able to build. ne of the big questions in biology is how intelligence came about wee using robotics to explore this mystery,
These adaptations allow biological organisms to survive in a wide variety of different environments allowing animals to make the move from living in the water to living on land, for instance.
said Iida. ut what we do have are a lot of enabling technologies that will help us import some aspects of biology to the engineering world. ource:
#Major Innovation in Molecular Imaging Delivers Spatial and Spectral Info Simultaneously Using physical chemistry methods to look at biology at the nanoscale,
and each subcellular structure was a distinct color. o using this method we can look at interactions between four biological components inside a cell in three-dimension and at very high resolution of about 10 nanometers,
Building on its strengths in biology computer science, psychology, statistics and engineering, CMU launched Brainhub, an initiative that focuses on how the structure and activity of the brain give rise to complex behaviors m
and quickly recreate microenvironments found across biology. To illustrate the potential of their technique, the Illinois team mixed breast cancer cells and cells called macrophages that signal cancer cells to spread
Kilian said his team synthetic microenvironment lies somewhere in the middle of two extremes in the field of modeling biology:
then you can ask fundamental biological questions. Kilian said these questions range from the basic how macrophages signal to the breast cells to the more long-term:
researchers can ask more sophisticated biological questions than they could, Kilian said. And they can do it quickly.
meaning they lack the kind of feedback control that most biological and engineering systems use to maintain a steady operating state.
demonstrating the value of bringing biological scientists together with engineers. Newman, an engineer by training, says concepts common in engineering can be useful in the life sciences. losed-loop control is a concept that is woven through all engineered systems,
but it often hard to find in the biological sciences, he said. ny time you can introduce feedback control into an experiment,
more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks.
keeping the whole biological machine running smoothly. But in diseases such as breast cancer, the breakdown of this order has been associated with the rapid growth
Genetic machinery for the production of those pigments was taken from other biological sources and introduced into the E coli.
and Wyss Institute Founding Director Donald Ingber, M d.,Ph d.,who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children Hospital and Professor of Bioengineering
#A fast cell sorter shrinks to cell phone size Commercially available cell sorters can rapidly and accurately aid medical diagnosis and biological research,
and biological research. Because the device is built on a lab-on-a chip system, it is both compact and inexpensive about the size and cost of a cell phone in its current configuration.
Lung and Blood Institute of the National institutes of health, published their work in a recent issue of Lab on a Chip. ell sorting is used widely in many areas of biology to characterize
as well as other fields in biology, in concomitantly overcoming all of these obstacles. It is quite easy to envision applications for this technology in diverse environments from a family doctor office to field studies in limnology.
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