who is also a professor of biology at MIT. his reporter is a very important tool.
existing approaches have offered limited insight into this fundamental biological control. Creating a system that dynamically visualizes methylation at the level of a single cell intrigued Yonatan Stelzer
and John van der Oost at Wageningen University, describe the unexpected biological features of this new system
and their natural biological function was described initially in 2010 and 2011. The application of the CRISPR-Cas9 system for mammalian genome editing was reported first in 2013, by Zhang and separately by George Church at Harvard university.
and proteins can be used to create materials that exhibit dynamic behaviors found in biological tissues like growth, morphogenesis, and healing.
First, it expands our knowledge of the biological role of Vitamin b12, which was understood already to help convert fat into energy,
says Catherine Drennan, a professor of chemistry and biology at MIT. The findings are detailed this week in the journal Nature.
says Rowena Matthews, a professor emerita of biological chemistry at the University of Michigan, who has read the paper.
fast, individualized and precise biomedical care. he REACH project is applied to cancer biology, but we have an even bigger vision than that,
although cancer biology is big enough, Morrison said. If big data is a two-part challenge,
The researchers evaluated the new test in two sets of biological samples for example, from blood, stool and nasal secretions from patients at St louis Children Hospital.
a biological material from living or recently living organisms, as a replacement for graphite, has drawn recent attention because of its high carbon content, low cost and environmental friendliness.
Nanocarbon architectures derived from biological materials such as mushrooms can be considered a green and sustainable alternative to graphite-based anodes,
Now, researchers at DTU Systems Biology have combined genetics with computer science and created a new diagnostic technology based on advanced self learning computer algorithms whichn the basis of a biopsy from a metastasisan with 85 per cent certainty identify the source of the disease
Associate professor Aron Eklund from DTU Systems Biology explains: e are pleased very that we can now use the same sequencing data together with our new algorithms to provide a much faster diagnosis for cancer cases that are difficult to diagnose,
or replaced by modern techniques that give the physician an indication of the elasticity of a biological tissue.
professor of neuroscience in Penn School of veterinary medicine and Perelman School of medicine, provides important clues for understanding how a father life experiences may affect his children brain development and mental health through a purely biological and not behavioral means. t remarkable to
Biologists construct phylogenetic trees to capture the evolutionary relationship between species, and help us better understand the functions and interactions of genes, the origin and spread of diseases, the co-evolution of hosts and parasites and migration of human populations.
ew insights into the biology of blood cancers and disorders that originate in the bone marrow have only been made possible by the latest advances in technology.
says the molecular biologist Prof. Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn.
Biological Crystallography and Chemical engineering Science. The chemistry of sequestering works this way: The enzyme, carbonic anhydrase, catalyzes a chemical reaction between carbon dioxide and water.
investigator Shingo Kajimura, Phd, an assistant professor of cell and tissue biology in UCSF School of dentistry. He holds a joint appointment in UCSF Diabetes Center and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.
#Biologist uncovers fundamental new strategy for destroying cancer cells University of Virginia cell biologist John Herr believes that the most ground-breaking findings always start with an insight built on basic science.
and opens opportunities for biological drug strategies that selectively target the gametes in the ovary and testis,
Herr said. ithout a deep level of understanding of the fundamental biology, commercial applications are not possible.
and a specialty of co-author Huilin Li, a molecular biologist at Brookhaven National Laboratory and Stony Brook University.
too big, says Peter Schultz, a Scripps biologist. Romesberg trained in Schultz lab.)Eventually, there could be bacteria producing entirely new proteins. o make a billion-dollar business, yes,
Researchers from the Salk Institute for Biological Studies in La jolla, California, have used the method, dubbed onogenetics,
because it really opens up new possibilities for how we modulate biology, said Jamie Tyler,
and biological fluids containing bacteria and blood. According to the researchers, all liquids were repelled, with the tungsten oxide actually making the steel stronger than steel without the coating.
"says Sanjeev Mariathasan, a biologist Genentech, the biotech company behind the study. That's a big problem because drugs that are used normally against staph infections can take over four hours to work far longer than it takes for Staph bacteria to move into new cells,
Security will be boosted by using biological information as a key the company said. Meanwhile, Samsung last week announced that it aims to become one of the top 10 global IT service companies in the world,
Understanding the interdependency of physiochemical properties of nanomedicines in correlation to their biological responses and functions is crucial for their further development of as cancer-fighters.
--and their interactions with biological systems explains Jianjun Cheng an associate professor of materials science and engineering at the University of Illinois at Urbana-Champaign.
and his collaborators systematically evaluated the size-dependent biological profiles of three monodisperse drug-silica nanoconjugates at 20 50 and 200 nm.
Cheng a Willett Faculty Scholar at Illinois is affiliated with the departments of Bioengineering and of Chemistry the Beckman Institute for Advanced Science and Technology the Micro and Nanotechnology Laboratory the Institute of Genomic Biology the Frederick
Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.
and surprising said study coauthor Huilin Li a biologist at Brookhaven Lab and Stony Brook University.
To our surprise we found an intermediate structure with one ORC binding two rings said Brookhaven Lab biologist
One step further along the researchers also determined the molecular architecture of the final double-ring structure left behind after the ORC leaves the system offering a number of key biological insights.
Precision methods close collaborationexamining these fleeting molecular structures required mastery of biology chemistry and electron microscopy techniques.
This proclivity for copper uptake is something we have known could be an Achilles'heel in prostate cancer tumors as well as other cancers said Donald Mcdonnell Ph d. chairman of the Duke Department of Pharmacology and Cancer Biology and senior author
Though a magnetic reversal is a major planet-wide event driven by convection in Earth's iron core there are no documented catastrophes associated with past reversals despite much searching in the geologic and biologic record.
We should be thinking more about what the biologic effects would be said Renne. Dating ash deposits from windward volcanoes The new finding is based on measurements of the magnetic field alignment in layers of ancient lake sediments now exposed in the Sulmona basin of the Apennine Mountains east of Rome Italy.
and Department of Plant Biology and co-author. They go into quiescence to conserve energy and nutrients.
This marriage of materials science and biology could give birth to a flexible sensitive coating that is easy and cheap to manufacture in large quantities.
The work to be published Oct 14 in the journal Nature Communications could lead to new types of biological sensors flow valves
Kumar's research team set out to create a biological version of a synthetic coating used in everyday liquid products such as paint
To create the biological equivalent of a polymer brush the researchers turned to neurofilaments pipe cleaner-shaped proteins found in nerve cells.
In biology precision is said critical Kumar. Proteins are synthesized generally with the exact same sequence every time;
This kind of sequence precision is difficult if not impossible to achieve in the laboratory using the tools of chemical synthesis. By harnessing the precision of biology
The study Self-association of an Insect Beta-13-Glucan Recognition Protein Upon Binding Laminarin Stimulates Prophenoloxidase Activation as an Innate Immune response was published recently in the Journal of Biological Chemistry.
Molecular biological analyses of tissue samples always confront scientists with the same problem: how to retrieve the genome of a specific pathogen from a mixture of DNAS in a patient and its microbial cohabitants?
In biology the term stress has a broader meaning: discovered and first described in 1936 by Viennese physician and biochemist Hans Selye stress is a psychological and physical reaction to external stimuli
Many mitochondrial diseases affect more than one system in the human body said Kateryna Makova professor of biology and one of the study's primary investigators.
Compared to molecules assembled without these hooks those incorporating the Suntag can greatly amplify biological activity.
CRISPR activation of genes can provide complementary biological insights. The adaptation of the Suntag for CRISPR activation makes it possible to systematically probe the biological roles of all genes within the genome in a single experiment.
The Weissman team used CRISPR activation to identify a number of tumor suppressor genes that inhibit the growth of cancer cells.
Ingber is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children's Hospital as well as professor of bioengineering at Harvard School of engineering and Applied sciences (SEAS.
His goal is to figure out precisely how histones contribute to basic biological functions and in turn contribute to cancers and other diseases.
and lungs for example and the various biological chemicals that simply make us tick. Proper nutrients for instance allow for the formation of chemical tags to direct the histones to activate genes in the proper ways.
Work the microbiome was pioneered by Washington University scientists led by Jeffrey Gordon MD the Dr. Robert J. Glaser Distinguished University Professor and director of the Center for Genome Sciences and Systems Biology.
or biological contaminants with far-reaching implications for public health including homeland security concerns. Applying world class research to water quality has to be viewed as a critical component for sustaining society as a whole says Clarkson University President Tony Collins. As healthy water becomes increasingly scarce establishing real-time data as the new standard for understanding water quality around the globe
and designed said Peng Yin senior author of the paper Wyss Core Faculty member and Assistant professor of Systems Biology at Harvard Medical school.
"In-field detection of chemical and biological threats is the challenge that we are trying to address,
"This technology can be used broadly for chemical and biological sensing, including homeland security, forensics and environmental monitoring,
and the University's Department of Stem Cell and Regenerative Biology--both of which were created more than a decade after he began his quest--said that
the Samuel A. Goldblith Professor of Applied Biology, Associate professor in the Department of Chemical engineering, the Institute of Medical Engineering and Science,
the Clyde and Helen Wu Professor of Chemical Biology (in Biomedical Informatics and the Institute for Cancer Genetics), chair of the Department of Systems Biology,
and repressing gene expression. or the first time we see that the structure of the chromosomes contributes to gene controlsays Whitehead Member Richard Young who is also a professor of biology at MIT. n the past there have been all kinds of ideas around how the structure might affect gene control
"The findings advance our understanding of the role of lncrnas in cancer biology and, importantly, broaden the opportunity to use lncrnas as biomarkers to detect prostate cancer."
Then the human's biological control system, that is nerves and muscles, is interfaced also to the machine's control system via neuromuscular electrodes.
between biology and mechatronics.""The direct skeletal attachment is created by what is known as osseointegration, a technology in limb prostheses pioneered by associate professor Rickard Brånemark and his colleagues at Sahlgrenska University Hospital.
Electrodes are implanted in nerves and muscles as the interfaces to the biological control system. These electrodes record signals which are transmitted via the osseointegrated implant to the prostheses,
who is also associate director of Weill Cornell's chemical biology program.""What we have shown in the Science study is that we now have the means to obtain real-time images of processes happening on the surface of intact HIV particles,
which contained beacons that did not alter the biology of the particles. Then they watched.
"The practical outcome from this technology is that we can begin to understand how the biological system moves.
and where these antibodies bind provides an important step forward to understanding HIV's biology, "he says.
real-time information to be obtained about molecular processes in complex biological systems
#Slime-producing molecules help spread disease from cats to endangered sea otters The spread of diseases from land animals to sea otters
#Smallest world record has ndless possibilitiesfor bionanotechnology Scientists from the University of Leeds have taken a crucial step forward in bionanotechnology a field that uses biology to develop new tools for science technology and medicine.
demonstrates how stable'lipid membranes'--the thin'skin'that surrounds all biological cells--can be applied to synthetic surfaces.
Importantly, the new technique can use these lipid membranes to'draw'--akin to using them like a biological ink--with a resolution of 6 nanometres (6 billionths of a meter
and promises the ability to position functional biological molecules--such as those involved in taste, smell,
"explained Evans. Aside from biological applications, this area of research could revolutionise renewable energy production. Working in collaboration with researchers at the University of Sheffield,
the researchers will be able to arbitrarily swap out the biological units and replace them with synthetic components to create a new generation of solar cells.
whereby engineering principles are being applied to biological parts --whether it is for energy capture, or to create artificial noses for the early detection of disease
However in the past decade scientists realized that exosomes play important roles in many biological functions through capsuling
or less to carry out multiple laboratory functions such as sample purification running of chemical and biological reactions and analytical measurement.
but the biological mechanisms involved are unknown. Researchers at Inserm Unit 1073 Nutrition inflammation and dysfunction of the gut-brain axis (Inserm/University of Rouen) have demonstrated the involvement of a protein produced by some intestinal bacteria that may be the source of these disorders.
#Non-coding half of human genome unlocked with novel sequencing technique An obscure swatch of human DNA once thought to be nothing more than biological trash may actually offer a treasure trove of insight into complex genetic-related diseases such as cancer
and diabetes thanks to a novel sequencing technique developed by biologists at Texas A&m University.
The game-changing discovery was part of a study led by Texas A&m biology doctoral candidate John C. Aldrich
and as a whole--would be packed with complex genes with the potential to answer some of the most pressing questions in medical biology.
unless biologists can look at the entire genome. We still can't--yet --but at least now we're a step closer.
which were published recently in Nature Chemical Biology and PNAS. Story Source: The above story is provided based on materials by Lund University.
And because the new process creates membranes on silicon surfaces it is a significant step toward creating bio-silicon interfaces where biological sensor molecules can be printed onto cheap silicon chip holding integrated electronic circuits.
because they offer the possibility of containing membrane proteins--biological molecules that could be used for detecting toxins diseases and many other biosensing applications.
and how to tackle them more effectively Revealing the intricate details of biological shapes is a hugely important step towards identifying targets for future cancer drugs.
The word I use is blindsiding says limnologist W. Charles Kerfoot a professor of biological sciences at Michigan Tech.
or your doctor office. s the biology and technology become further refined, the authors say that their approach could potentially be a more efficient, more effective,
and other biological components. n the biological domain, there are various molecules and atoms in contact with one another, sliding along like biomolecular motors,
from the nanoscale to the macroscale. he applications and related impact of their novel method propels a huge variety of research fields investigating effects relevant from raft tectonics down to biological systems
The ability to precisely control droplets using fluidic computation could have a number of applications in high-throughput biology and chemistry,
. an associate professor of biological sciences and physics at Columbia University and the paper lead author. vaporation is a fundamental force of nature,
with a possible focus on filtering biological contaminants from groundwater to make it safe to drink. There are already a number of filters on the market that can do this,
The system is equipped also to treat the biological contaminants that Wright initially thought she be treating,
It is common for these so-called chiral molecules to exist in just one form in biological systems,
and biological research. These devices are usually too large to be portable, but MIT scientists have shown now they can create spectrometers small enough to fit inside a smartphone camera,
which have been used primarily for labeling cells and biological molecules, as well as in computer and television screens. sing quantum dots for spectrometers is such a straightforward application compared to everything else that wee tried to do,
Based on current scientific models of eczema biology, assistant professor of dermatology Dr. Brett King. hypothesized that a drug approved for rheumatoid arthritis,
using biologics and small molecules to halt radiation harmful effects in the field. Some block cell death and protect damaged tissue exposed to radiation;
and biological attacks. These government awards include more than $500 million for the treatment and prevention of ARS.
The only difference is that we are using biology to make it, and we are using renewable raw materials.
the closed-loop robo-pancreas is ahead of such biological approaches, says IRCM Haidar, even though it will never duplicate the human body. e know an airplane isn better than a bird,
high-energy photon has potential applications in biological imaging, high-density data storage, and organic light-emitting diodes (OLEDS) L
analyze the chemical, biological, and radiological threats before someone actually gets to the fire. Police have been buying up drones for years now,
When technology meets biology the interface is rarely flawless and the devices often hinder the bodies they are supposed to help.
a world in which technology erases disability and in which the synthetic and biological worlds meld seamlessly.
Daniel Ferris director of the Human Neuromechanics Laboratory at the University of Michigan says that Herr's strength is knowing the biological mechanisms
While many engineers have built robotic devices for movement none have matched really Hugh's ability to fuse biology with engineering.
Redefining the Good Bodyin spite of the practical challenges Herr has a far-reaching vision for melding technology with biology.
One way of doing this is to carbonize biological material, such as fruit or coconut shell. This means heating the material to few hundred degrees centigrade in a nitrogen atmosphere
which ensures that the carbon retains its porous biological structure. Instead of coconut shell, Dixit and co carbonized coconut flesh.
and making sure the genes are stable says Dean Price a professor of medicine biology and environment at Australian National University.
Its founders among them the Nobel laureate and MIT biologist Philip Sharp had solved one of the biggest challenges facing the idea of RNAI therapies.
Poon and her team found a way to use electromagnetic induction through biological tissue without that exponential decay.
When they send current through the plate that pattern produces a magnetic field capable of propagating through biological material without decaying over a short distance.
One of her graduate students is also designing plates that will penetrate materials other than biological tissue.
#Terahertz Chip Identifies Short Strands of DNA One of the more significant practical challenges currently occupying molecular biologists is to find better ways of identifying short strands of DNA.
But molecular biologists would like a better system that measures the characteristics of the molecules involved
you could actually do a lot in terms of reading biological signals related to the health of a person,
a professor of chemistry and chemical biology, turned to nature for an alternative approach, taking inspiration from the pitcher plant,
are compounds far smaller than less common biological medicines like antibodies. They are developed using libraries of thousands or millions of known chemical substances.
if it has desired a effect on a biological target such as an enzyme or other protein known to be involved in a disease.
which a biological scaffold is sutured in. Within two days, the patients began an intensive physical therapy regimen that helps direct the development of stem cells in the body that are drawn to the implant.
The methods developed to create the designer genomic structure could help synthetic biologists better use the single-celled fungi as biological factories for chemicals like biofuels and drugs.
or potentially make their biological production more efficient. Six years ago, the J. Craig Venter Institute built the first artificial chromosome,
The findings have been accepted by the international journal'Biological Psychiatry'for publication.""A total 130 people0 Alzheimer's patient, 41 patients suffering from mild cognitive impairment and 49 healthy individualsarticipated in the study.
and this has got applications in chemistry, engineering, biology, medicine, so there's a lot of potential there and that's just for research purposes,
and this has got applications in chemistry, engineering, biology, medicine, so there's a lot of potential there and that's just for research purposes,
Kevin Harrington, UK trial leader and professor of biological cancer therapies at the ICR and an honorary consultant at the Royal Marsden, said he hoped the treatment could be available for routine use within a year in many countries
Kevin Harrington, UK trial leader and professor of biological cancer therapies at the ICR and an honorary consultant at the Royal Marsden, said he hoped the treatment could be available for routine use within a year in many countries
since proteins carry out many biological functions.""In this particular disease, we think a mutation in the ATF6 gene disrupts the UPR process
hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.
hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.
hepatitis and herpes. Researchers from Moscow Institute of Physics and Technology (MIPT) developed the ultracompact nanomechanical sensor for analysing the chemical composition of substances and detecting biological objects.
"said Yingfu Li, a professor in the Departments of Biochemistry and Biomedical sciences, Chemistry and Chemical Biology."
"This discovery was made possible by using 30 years of data and biologic specimens. Rappocciolo and her colleagues searched for patterns in gene expression,
and are compared often to the biological structure of cartilage. While the development of the 3d printable hydrogels is certainly a breakthrough for Zhao and the rest of the team,
#MEDPRIN 3d prints world first biological meningioma Redura for use in brain surgery While 3d bioprinting innovations sound lifesaving and revolutionary, most are still years away from impacting ordinary
Called MEDPRIN, they have developed the world first 3d printed biological meningioma called Redura a replica of tissue covering the brain
they are not biological and have a tendency to disrupt a patient life-as most artificial meningioma layers contain metal parts
this 3d printed biological Redura doesn suffer from these problems, but instead closely resembles the existing membrane and a patient autologous cells.
the machine sprays out a fiber-like ink onto biological paper that simulates the collagen structures found in body.
and clinical resources to push 3d printing from biological tissue reconstruction all the way up to 3d printing of organ regeneration.
thus inducing greater biological damage. In this study, the authors analysed the spectra of secondary electrons emitted from a carbon nanoparticle composed of fullerite,
This work was headed by Huilin Li, Brookhaven Lab and Stony Brook University biologist, and Tong Wang, the other lead co-author of the paper and who also works with Li in the Biosciences department of Brookhaven.
The project goal is to develop new tools to elucidate the mechanism of action of a threat agent, drug, biologic or chemical on living cells within 30 days from exposure.
96 spot, target plate, suitable for simple and complex biological mixtures, and compatible with most standard MALDI-MS instrument systems.
"A new reliable biological standard is particularly attractive to the electron microscopy community as it has the potential to offer a cost effective solution for high-resolution imaging."
In their setup, a sphere was placed on one of the prongs--in a biological system
"Future work for Yabuno and his colleagues involves using the cantilevers to obtain high-accuracy quantitative measurements of biological samples such as human cells and DNA in liquid media d
and other biological parts. n the biological domain, there are various molecules and atoms in contact with one another, sliding along like biomolecular motors,
and related impact of their novel method propels a huge variety of research fields investigating effects relevant from raft tectonics down to biological systems
"This opens up a completely new frontier where we can explore the interface between electronic structures and biology.
but no one has addressed this issue-the electronics/cellular interface-at the level at which biology works."
"The idea of merging the biological with the electronic is not a new one for Lieber.
a process common to delivery of many species in biology and medicine-you could go to the doctor
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