Starting with a solution of colloidal nanorods Yang and Ni built on the common self-assembly technique used to build nanoparticles.
The method developed in Zhang's research group can be applied to many other nanoparticles; indeed almost any structure that can self-assemble could be produced in this way.
#A quantum leap in nanoparticle efficiency (Phys. org) New research has unlocked the secrets of efficiency in nanomaterials that is materials with very tiny particles
Researchers found the precise geometry of nanoparticle pairs that maximises light concentration resolving a hotly debated area of quantum physics.
This geometry now determines the efficiency nanoparticle use as a chemical sensor in sensing minute quantities of chemicals in air and water.
concentration for fabricated nanoparticles. Professor Crozier said This work is important for engineers and scientists working in the nanomaterial industry y
they were able to quantify the relationship between the CARS light intensity and the nanoparticle size.
Gold nanoparticles on the surface of the receptacle change the colour of the light detected by the instrument.
Roughly, it measures the concentration of serum (or blood) methotrexate through gold nanoparticles on the surface of a receptacle.
the gold nanoparticles change the colour of the light detected by the instrument. And the colour of the light detected reflects the exact concentration of the drug in the blood sample.
#Nanoparticle technology triples the production of biogas Researchers of the Catalan Institute of Nanoscience and Nanotechnology (ICN2), a Severo Ochoa Centre of Excellence,
which allows increasing the production of biogas by 200%with a controlled introduction of iron oxide nanoparticles to the process of organic waste treatment.
The development of Biogàsplus was carried out by the ICN2's Inorganic nanoparticle group, led by ICREA researcher Víctor Puntes,
The system is based on the use of iron oxide nanoparticles as an additive which"feeds"the bacteria in charge of breaking down organic matter.
and at the same time transforms the iron nanoparticles into innocuous salt.""We believe we are offering a totally innovative approach to the improvement of biogas production and organic waste treatment,
since this is the first nanoparticle application developed with this in mind. In addition, it offers a significant improvement in the decomposition of organic waste
Applied Nanoparticles, a Gateway to the Market"Our idea is the result of many projects:
"We were studying the toxicity of iron oxide nanoparticles in the waste treatment of anaerobic biological processes when we discovered that not only were they not toxic,
With that in mind, they created Applied Nanoparticles, gestated at the ICN2 and currently in the process of signing a knowledge transfer agreement with the UAB."
The grant money went towards testing the capacity of iron oxide nanoparticles, which helped to verify the efficacy of its application in a pilot 100 litre digester.
The cost of this new nanofluid (to which nanoparticles are added in order to enhance and improve heat conductivity) is similar to that of the base fluid,
since both the nanoparticles and the stabilizers used are inexpensive. All these features make it suitable for industrial applications that employ heat transmission/exchange systems.
and increases the thermal conductivity by adding an exact proportion of nanoparticles consisting on carbon and other additives to the base fluid (diphenyl/diphenyl oxide),
which means that it does not give rise to any problems with pumping, the precipitation of nanoparticles or the obstruction of conduits.
because both the nanoparticles and the stabilizers used are abundant, readily accessible and inexpensive e
10.1038/nnano. 2014.211 An addressable quantum dot qubit with fault-tolerant control-fidelity Nature Nanotechnology DOI:
#DNA nanofoundries cast custom-shaped 3-D metal nanoparticles Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard university have unveiled a new method to form tiny 3d metal nanoparticles
The ability to mold inorganic nanoparticles out of materials such as gold and silver in precisely designed 3-D shapes is a significant breakthrough that has the potential to advance laser technology microscopy solar cells electronics environmental testing
We built tiny foundries made of stiff DNA to fabricate metal nanoparticles in exact three-dimensional shapes that we digitally planned
The paper's findings describe a significant advance in DNA NANOTECHNOLOGY as well as in inorganic nanoparticle synthesis Yin said.
For the very first time a general strategy to manufacture inorganic nanoparticles with user-specified 3d shapes has been achieved to produce particles as small as 25 nanometers or less with remarkable precision (less than 5 nanometers.
The 3d inorganic nanoparticles are conceived first and meticulously planned using computer design software. Using the software the researchers design three-dimensional frameworks of the desired size
and expanded to fill all existing space within the DNA framework resulting in a cuboid nanoparticle with the same dimensions as its mold. with the length width
Next researchers fabricated varied 3d polygonal shapes spheres and more ambitious structures such as a 3d Y-shaped nanoparticle and another structure comprising a cuboid shape sandwiched between two spheres proving that structurally-diverse
nanoparticles could be shaped using complex DNA mold designs. Given their unthinkably small size it may come as a surprise that stiff DNA molds are proportionally quite robust and strong able to withstand the pressures of expanding inorganic materials.
Although the team selected gold seedlings to cast their nanoparticles there is a wide range of inorganic nanoparticles that can be shaped forcibly through this process of DNA nanocasting.
A very useful property is that once cast these nanoparticles can retain the framework of the DNA mold as an outer coating enabling additional surface modification with impressive nanoscale precision.
#Nanoparticle research could enhance drug delivery through skin Scientists at the University of Southampton have identified key characteristics that enhance a nanoparticle's ability to penetrate skin in a milestone study which could have major implications for the delivery of drugs.
Nanoparticles are up to 100000 times smaller than the thickness of a human hair and drugs delivered using them as a platform can be concentrated more targeted
Although previous studies have shown that nanoparticles interact with the skin conditions in these experiments have not been controlled sufficiently to establish design rules that enhance penetration.
and functionality (controlled through surrounding molecules) of gold nanoparticles to see how these factors affect skin penetration.
By creating nanoparticles with different physicochemical characteristics and testing them on skin we have shown that positively charged nanorod shaped nanoparticles are two to six times more effective at penetrating skin than others says lead author Dr Antonios Kanaras.
When the nanoparticles are coated with cell penetrating peptides the penetration is enhanced further by up to ten times with many particles making their way into the deeper layers of the skin (such as the dermis.
Establishing which characteristics contribute to penetration is also important in discovering ways to prevent potentially toxic nanoparticles in other materials such as cosmetics from entering the skin.
The research which has been published in the journal Small drew on the medical expertise of Dr Neil Smyth and Dr Michael Ardern-Jones as well as contributions from physicist Professor Otto Muskens.
#Drug-infused nanoparticle is right for sore eyes For the millions of sufferers of dry eye syndrome their only recourse to easing the painful condition is to use drug-laced eye drops three times a day.
Now researchers from the University of Waterloo have developed a topical solution containing nanoparticles that will combat dry eye syndrome with only one application a week.
The eye drops progressively deliver the right amount of drug-infused nanoparticles to the surface of the eyeball over a period of five days before the body absorbs them.
The nanoparticles about 1/1000th the width of a human hair stick harmlessly to the eye's surface and use only five per cent of the drug normally required.
You can't tell the difference between these nanoparticle eye drops and water said Shengyan (Sandy) Liu a Phd candidate at Waterloo's Faculty of engineering who led the team of researchers from the Department of Chemical engineering and the Centre for Contact lens Research.
if we focused on infusing biocompatible nanoparticles with Cyclosporine A the drug in the eye drops
The research team is now focusing on preparing the nanoparticle eye drops for clinical trials with the hope that this nanoparticle therapy could reach the shelves of drugstores within five years.
#Targeted nanoparticles that combine imaging with two different therapies could attack cancer other conditions Nanosystems that are'theranostic'they combine both therapeutic and diagnostic functions present an exciting new opportunity for delivering drugs
and Engineering and colleagues at the National University of Singapore have created nanoparticles with two distinct anticancer functions
The nanoparticles also include the cell-targeting property essential for treating and imaging in the correct locations.
The natural fluorescence of the polymer assists with diagnosis and monitoring of therapy as it shows where nanoparticles have accumulated.
of which overexpressed a surface protein that could bind to the targeting peptide on the nanoparticles.
Fluorescence imaging indicated that the nanoparticles were taken up by the target cells and that ROS and doxorubicin were released within these cells all at significantly higher levels than in cells used as controls.
Introducing the multitasking nanoparticle More information: Yuan Y. Liu J. & Liu B. Conjugated-polyelectrolyte-based polyprodrug:
#Nanoparticles break the symmetry of light How can a beam of light tell the difference between left and right?
Gold nanoparticles on Glass fibres When a particle absorbs and emits light, this light is emitted not just into one direction."
His team has succeeded now in breaking this symmetry of emission using gold nanoparticles coupled to ultra-thin glass fibres.
This effect has now been demonstrated using a single gold nanoparticle on a glass fibre. The fibre is 250 times thinner than a human hair;
#Researcher develops optically traceable smart 2-D nanosheet that responds to ph Nanoparticles have the potential to revolutionize the medical industry
Finally they need to perform their function at the right moment ideally in response to a stimulus. The Nanoparticles By design Unit at the Okinawa Institute of Science
#'Stealth'nanoparticles could improve cancer vaccines Cancer vaccines have emerged recently as a promising approach for killing tumor cells before they spread.
And the key they report in the journal ACS Nano is in the vaccine's unique stealthy nanoparticles.
if stealthy nanoparticles they had developed and clinically tested in patients might hold the answer. The researchers injected the nanoparticles into mice.
They found that the particles which have no electric charge or surface molecules that would attract the attention of circulating immune cells were able to enter the mice's lymph nodes.
When molecules for signaling killer T cells were put inside the nanoparticles they hindered tumor growth far better than existing vaccines.
Nanogel-Based Immunologically Stealth Vaccine Targets Macrophages in the Medulla of Lymph node and Induces Potent Antitumor Immunity ACS Nano 2014 8 (9) pp 9209#9218.
We developed a nanoparticulate cancer vaccine by encapsulating a synthetic long peptide antigen within an immunologically inert nanoparticulate hydrogel (nanogel) of cholesteryl pullulan (CHP.
After subcutaneous injection to mice the nanogel-based vaccine was transported efficiently to the draining lymph node and was engulfed preferentially by medullary macrophages
The nanogel-based vaccine significantly inhibited in vivo tumor growth in the prophylactic and therapeutic settings compared to another vaccine formulation using a conventional delivery system incomplete Freund's adjuvant.
which may underlie the potency of the macrophage-oriented nanogel-based vaccine. These results indicate that targeting medullary macrophages using the immunologically stealth nanoparticulate delivery system is an effective vaccine strategy e
#Nanoparticles accumulate quickly in wetland sediment (Phys. org) A Duke university team has found that nanoparticles called single-walled carbon nanotubes accumulate quickly in the bottom sediments of an experimental wetland setting an action they say could indirectly damage the aquatic food chain.
if the nanoparticles provide Trojan horse piggyback rides to other harmful molecules. The results appear online in the journal Environmental science:
They found that the vast majority of the nanoparticles quickly accumulated in the sediment on the pond floor.
However they found no sign of nanoparticle buildup in any plants insects or fish living in the mesocosms.
These nanoparticles are really good at latching onto other molecules including many known organic contaminants said Ferguson.
The nanoparticle-pollutant package could then be eaten by sediment-dwelling organisms in a sort of'Trojan horse'effect allowing the adsorbed contaminants to accumulate up the food chain.
which incorporates biomaterial harvested from patients and gold nanoparticles.""Our goal was said twofold Dr. Dvir.""To engineer tissue that would not trigger an immune response in the patient,
"At his Laboratory for Tissue Engineering and Regenerative medicine, Dr. Dvir explored the integration of gold nanoparticles into cardiac tissue to optimize electrical signaling between cells."
we deposited gold nanoparticles on the surface of our patient-harvested matrix, 'decorating'the biomaterial with conductors,
"The result was that the nonimmunogenic hybrid patch contracted nicely due to the nanoparticles, transferring electrical signals much faster and more efficiently than non-modified scaffolds."
In the form of nanowires and nanoparticles it has particular potential for use in the manufacture of solar cells
They deposited metal nanoparticles on a silicon wafer and etched nanowires using aqueous H2o2. Although the researchers did not have precise control over the nanowire morphology they did observe that higher concentrations of H2o2 led to thicker nanowires.
Further observations of the morphology identified silicon nanocrystals at the nanowire ends which was corroborated by Raman studies of single nanowires.
These nanocrystals disappear on annealing as does the red photoluminescence. The researchers attribute the red photoluminescence to defect states between nanocrystals and surrounding oxide and excitonic transitions.
As the researchers conclude in their report These results of Si nanowire arrays are believed to be useful for future optoelectronic and photovoltaic applications.
then the National Institute of Standards and Technology (NIST) can now make anyone working with nanoparticles very happy.
the nanocrystals are etched from a silicon wafer, separated using ultrasound and then stabilized within an organic shell.
"For anyone working with nanomaterials at dimensions 5 nanometers or less, our well-characterized nanoparticles can ensure confidence that their measurements are accurate,
Silicon nanoparticles such as those in RM 8027 are being studied as alternative semiconductor materials for next-generation photovoltaic solar cells and solid-state lighting,
silicon nanoparticles may one day serve as easily detectable"tags"for tracking nanosized substances in biological, environmental or other dynamic systems s
We exploit the'self-organization'of semiconducting nanocrystals by the'Stranski-Krasnov (SK) mode of crystal growth for producing ordered highly dense
Notably electrons in quantum dot structures are confined inside nanometer sized three dimension boxes. Novel applications of'quantum dots'including lasers biological markers qubits for quantum computing
This density was one of the critical advances for achieving high efficiency quantum dot based photovoltaic devices says Yamaguchi.
dx. doi. org/10.1143/APEX. 5. 125502 Katsuyoshi Sakamoto Yasunori Kondo Keisuke Uchida and Koichi Yamaguchi Quantum dot density dependence of power conversion
Polymersome magneto-valves for reversible capture and release of nanoparticles. Nature Communications DOI: 10.1038/ncomms601 6
and hard-wearing nanocomposites is obtaining an even distribution of the nanoparticles in the metal matrix.
They then injected a slurry of aluminum oxide nanoparticles into the holes and heated the sheet in an oven.
Placing the nanoparticles in the sheet prior to the friction stir processing step significantly increased the concentration of nanoparticles in the composite.
They first demonstrated that the nanoparticles were dispersed uniformly which means the material has no weak points.
and without the Al2o3 nanoparticles the team showed that the nanoparticles contributed to the reduction in grain size.
The best nanoparticle distribution and smallest aluminum alloy grains were obtained after passing the rotating tool through the sheet four times.
Scientists use nanoparticles to control growth of materials More information: Guo J. F. Liu J. Sun C. N. Maleksaeedi S. Bi G. et al.
#Gold nanoparticles linked to single stranded-dna DNA create a simple but versatile genetic testing kit Tests for identifying genetic variations among individuals
The researchers used gold nanoparticles attached to short sections of DNA that bind to specific complementary sequences of DNA through the base pairing that holds together double-stranded DNA.
#Experts create unique nanoparticles for aerospace industry A development of three universities enables improved thermal and electronic properties on devices with nickel-titanium alloys.
Experts collaborated to produce nanoparticles made of a titanium-nickel alloy used in the development of thermal and electrical sensors that control the operation of high-tech devices such as those used in aerospace,
Meanwhile, the team at the UANL manufactured nanoparticles used in the sensors, and after a series of tests confirmed the effectiveness of the titanium-nickel as an electrical and thermal conductor.
With nanoparticles, they produced temperature-sensitive devices that transmit electrical energy to the system but do not cause overheating.
Then nanoparticles were obtained by thermal evaporation techniques where the molecular bonds of the metals degraded as a powder
Besides generating nanoparticles for sensors, another goal of this proyect is to train high level human resources in the areas of metallurgy alloys with shape memory,
Using an optical microstructure and gold nanoparticles, they have amplified the interaction of light with DNA to the extent that they can now track interactions between individual DNA molecule segments.
These protons make their way to the platinum nanoparticles which sit on top of the titanium dioxide. Hydrogen is produced by the interaction of the protons
For this study scientists looked at a positive electrode made of billions of nanoparticles of lithium iron phosphate.
Previous studies produced conflicting views of how the nanoparticles behaved. To probe further researchers made small coin cell batteries charged them with different levels of current for various periods of time quickly took them apart
We were able to look at thousands of electrode nanoparticles at a time and get snapshots of them at different stages during charging
Analyzing the data using a sophisticated model developed at MIT the researchers discovered that only a small percentage of nanoparticles absorbed and released ions during charging even
Aligned CNTS were intercalated firstly into the interlayer spaces of the layered catalyst embedded with metal nanoparticles (NPS) through a low-temperature (L-T) CVD
#'Human touch'nanoparticle sensor could improve breast cancer detection (Phys. org) niversity of Nebraska-Lincoln scientists have developed a nanoparticle-based device that emulates human touch
In research funded with a grant from the National institutes of health, Saraf and Nguyen perfected a thin film made of nanoparticles and polymers
a tunneling barrier, a quantum dot, another tunneling barrier, and a drain electrode to suppress electron excitation
#Researcher's nanoparticle key to new malaria vaccine A self-assembling nanoparticle designed by a UCONN professor is the key component of a potent new malaria vaccine that is showing promise in early tests.
But a novel protein nanoparticle developed by Peter Burkhard, a professor in the Department of Molecular & Cell biology, in collaboration with David Lanar
The key to the vaccine's success lies in the nanoparticle's perfect icosahedral symmetry (think of the pattern on a soccer ball)
We are able to achieve our high density because of the design of the nanoparticle, which we control."
It took the researchers more than 10 years to finalize the precise assembly of the nanoparticle as the critical carrier of the vaccine
holds the patent on the self-assembling nanoparticle used in the malaria vaccine. Burkhard is also exploring other potential uses for the nanoparticle,
including a vaccine that will fight animal flu and one that will help people with nicotine addiction.
Guiding Brain tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-held Raman Scanner ACS Nano Article ASAPDOI:
Here we evaluated the ability of a hand-held Raman scanner guided by surface-enhanced Raman scattering (SERS) nanoparticles to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model.
and correlation with histology showed that SERS nanoparticles accurately outlined the extent of the tumors.
because it uses inert gold#silica SERS nanoparticles and a hand-held Raman scanner that can guide brain tumor resection in the operating room o
#Color hologram uses plasmonic nanoparticles to store large amounts of information In the 4th century, the Romans built a special glass cup,
Similar to the Lycurgus cup, the new holograms can change colors due to light scattering off silver nanoparticles of specific sizes and shapes.
The new holograms consist of precisely engineered silver nanoparticles patterned over a substrate. A key difference in the new holograms is the smaller size of the diffraction fringes,
the fringes here are replaced with nanoparticles smaller than half the wavelength of light. The researchers showed that the narrower band diffraction,
For instance, two different types of plasmonic nanoparticles can be multiplexed, or combined but not coupled, at subwavelength distances.
By using nanoparticles of silver with different shapes and sizes, the researchers could control the colors.
In addition to providing multiple colors, multiplexing two nanoparticles has the advantage of increasing the bandwidth information limits.
The researchers showed that each nanoparticle carries independent information such as polarization and wavelength, which can be controlled simultaneously.
With twice the number of nanoparticles, the total amount of binary information stored can exceed the traditional limits of diffraction."
"It has been shown that nanoparticles with resonant properties can be uncoupled over subwavelength distances so their electromagnetic fields have minimal interaction,
"The device presented demonstrates that these nanoparticles can store and transfer independent information beyond the diffraction limits,
#Eco-friendly'prefab nanoparticles'could revolutionize nano manufacturing A team of materials chemists polymer scientists device physicists
and others at the University of Massachusetts Amherst today report a breakthrough technique for controlling molecular assembly of nanoparticles over multiple length scales that should allow faster cheaper more ecologically friendly manufacture of organic photovoltaics and other electronic devices.
It was Bag who put similar sized and charged nanoparticles together to form a building block then used an artist's airbrush to spray layers of electrical circuits atop each other to create a solar-powered device.
#Magnetic nanoparticles break the capacity barrier for antibody purification Monoclonal antibodies represent the largest and fastest-growing segment of international biopharma.
Now A*STAR researchers have developed a high-capacity method to purify monoclonal antibodies that uses magnetic nanoparticles and also introduces new operating conditions.
which causes the antibodies to be deposited on the surface of starch-coated magnetic nanoparticles (see image).
The high capacity of our nanoparticle method makes it much faster than column chromatography explains Gagnon.
In addition to solving the longstanding problem of productivity for monoclonal antibodies the nanoparticle approach can be applied to many other therapeutic proteins and also to viral vaccines.
Gagnon P. Toh P. & Lee J. High productivity purification of Immunoglobulin g monoclonal antibodies on starch-coated magnetic nanoparticles by steric exclusion of polyethylene glycol.
and composition of the nanorods means it is easier to control the properties of the bimetallic goldopper nanoparticles compared to nanoparticles made of just one metal,
Her team now plans to use the nanorods as seeds themselves to synthesize nanoparticles comprised of a goldopper core surrounded by a shell of another material, such as platinum, for energy applications
In order to view the behaviour of the cell membrane at the level of individual molecules the Cambridge team working with researchers from the University of Leeds squeezed them into a tiny gap between the mirrored gold facets of a nanoparticle sitting just above a flat gold surface.
The film can be applied onto degradable nanoparticles for injection into local sites or used to coat permanent devices such as orthopedic implants.
Yung-Eun Sung is both a group leader at the Center for Nanoparticle Research at Institute for Basic Science*(IBS) and a professor at the Seoul National University.
Group leader Yung-Eun Sung of the Center for Nanoparticle Research at IBS, says,"We expect that our synthetic approach will be developed to produce doped carbon materials based on other elements (e g.,
#Self-assembling nanoparticle could improve MRI scanning for cancer diagnosis Scientists have designed a new self-assembling nanoparticle that targets tumours,
The new nanoparticle, developed by researchers at Imperial College London, boosts the effectiveness of Magnetic resonance imaging (MRI) scanning by specifically seeking out receptors that are found in cancerous cells.
The nanoparticle is coated with a special protein, which looks for specific signals given off by tumours,
causing the nanoparticle to self-assemble into a much larger particle so that it is more visible on the scan.
used cancer cells and mouse models to compare the effects of the self-assembling nanoparticle in MRI scanning against commonly used imaging agents
and found that the nanoparticle produced a more powerful signal and created a clearer MRI image of the tumour.
The scientists say the nanoparticle increases the sensitivity of MRI scanning and will ultimately improve doctor's ability to detect cancerous cells at much earlier stages of development.
The newly designed nanoparticle provides a tool to improve the sensitivity of MRI scanning, and the scientists are now working to enhance its effectiveness.
so that the nanoparticle would light up with a luminescent probe once it had found its target,
"Before testing and injecting the nontoxic nanoparticle into mice, the scientists had to make sure that it would not become so big
They injected the nanoparticle into a saline solution inside a petri dish and monitored its growth over a four hour period.
The nanoparticle grew from 100 to 800 nanometres still small enough to not cause any harm.
The scientists are now improving the nanoparticle and hope to test their design in a human trial within the next three to five years.
"We're now looking at fine tuning the size of the final nanoparticle so that it is even smaller
Overtext Web Module V3.0 Alpha
Copyright Semantic-Knowledge, 1994-2011