| Gold nanoparticle (94) |  |
| Inorganic nanoparticle (12) | |
| Magnetic nanoparticle (35) | |
| Metal nanoparticle (49) | |
| Nanocrystal (322) | |
| Nanodisk (9) | |
| Nanogel (7) | |
| Nanoparticle (1347) | |
| Nanoplatelet (13) | |
| Oxide nanoparticle (15) | |
| Silver nanoparticle (40) | |
| Zinc oxide nanoparticle (7) | |
the partners incorporated nanoparticles and micro-or nano-sized pigments into coatings and surface layers. e implemented this technology for three types of material:
and enhance the efficiency of the treatment. he decorating of nanoparticles very tiny particles with cyclodextrins allows us to play with the functionality,
A decorated approach Dr Yannakopoulou says that progress in delivery efficiency has already been made through decorating nanoparticles with cyclodextrins combined with nhanced Permeability and Retention EPR) the property by
and thus tend to accumulate in tumour tissue much more than they do in normal tissues. e have been able to play with the sizes of nanoparticles to make them big enough to get into the tumour cells,
Dr de la Rica made the decision to grow metal nanocrystals rather than the traditional calcium phosphate crystals as a way to generate a signal.
The solution that they came up with is to use very hard alumina nanoparticles and spread them evenly in the polysulfone,
'This innovation allows nanoparticles to be incorporated and evenly dispersed in a polymer mould in a very low proportion.
and other goods. The Flexpakrenew research team developed a number of new techniques that use renewable materials reinforced with nanoparticles and innovative coatings.
##The shoebox-sized prototype diagnostic device known as the single particle interferometric reflectance imaging sensor (SP-IRIS) detects pathogens by shining light from multicolor LED sources on viral nanoparticles bound to the sensor surface by a coating
and can capture the telltale responses of up to a million nanoparticles. In collaboration with BD Technologies and Nexgen Arrays a start-up based at the Photonics Center
transistors, and diodes that guide magnetic beads and single cells tagged with magnetic nanoparticles through a thin liquid film.
and nanoparticles can be used to image live cells. To study the channels the team engineered variants of tarantula toxin that could be labeled fluorescently
The technology uses aluminum nanoparticles to create the vivid red blue and green hues found in today s top-of-the-line LCD televisions and monitors.
the phosphorous acid reduces the copper ions to copper nanoparticles. The nanoparticles attract electrons from the silicon wafer surface,
oxidizing it and allowing hydrogen fluoride to burn inverted pyramid-shaped nanopores into the silicon. Fine-tuning the process resulted in a black silicon layer with pores as small as 590 nanometers (billionths of a meter) that let through more than 99 percent of light.
University of Toronto rightoriginal Studyposted by Marit Mitchell-Toronto on June 9 2014those flat glassy solar panels on your neighborâ#roof may be getting a more efficient makeover thanks to a new class of solar-sensitive nanoparticles.
This new form of solid stable light-sensitive nanoparticles called colloidal quantum dots could lead to cheaper and more flexible solar cells as well as better gas sensors infrared lasers infrared light emitting diodes and more.
and demonstrated a new colloidal quantum dot n-type material that does not bind oxygen when exposed to air.
But improved performance is just a start for the new quantum dot-based solar cell architecture. The powerful little dots could be mixed into inks
and accessibility of solar power for millions of people. he field of colloidal quantum dot photovoltaics requires continued improvement in absolute performance
and then used it to move nanoparticles of cadmium disulfide along the length of a nanotube.
The nanoparticle is fluorescent in visible light and the nanotubes are fluorescent in the near-infrared.
or the first time we predicted their properties using quantum mechanics. he nanocrystals are about 3 nanometers wide by 500 nanometers longor about 1/1000th the width of a grain of sandmaking them too small to study with light microscopes
The findings represent a milestone in understanding the fundamental mechanical behavior of the cellulose nanocrystals. t is also the first step towards a multiscale modeling approach to understand
and medical devices to structural components for the automotive civil and aerospace industries. he cellulose nanocrystals represent a potential green alternative to carbon nanotubes for reinforcing materials such as polymers and concrete.
A small change in the size of a quantum dot as little as a fraction of a nanometer##changes its fluorescent wavelengths by a measurable factor
So this discovery can really change the quantum dot industry. It'#going to show the world that inside of coal are these very interesting structures that have real value. he Air force Office of Scientific research
#DNA helps nanoparticle crystals self-assemble Northwestern University rightoriginal Studyposted by Megan Fellman-Northwestern on December 2 2013using the same structure found in nature researchers have built the first near-perfect single crystals
out of gold nanoparticles and DNA. ingle crystals are the backbone of many things we rely onâ##diamonds for beauty as well as industrial applications sapphires for lasers
Given a set of nanoparticles and a specific type of DNA Olvera de la Cruz showed they can accurately predict the 3d structure
The team worked with gold nanoparticles but the recipe can be applied to a variety of materials with potential applications in the fields of materials science photonics electronics
In the study strands of COMPLEMENTARY DNA act as bonds between disordered gold nanoparticles transforming them into an orderly crystal.
The researchers determined that the ratio of the DNA linker s length to the size of the nanoparticle is critical. f you get the right ratio it makes a perfect crystalâ##isn t that fun?
and realized experimentally. o achieve a self-assembling single crystal in the lab the research team reports taking two sets of gold nanoparticles outfitted with COMPLEMENTARY DNA
Working with approximately 1 million nanoparticles in water they heated the solution to a temperature just above the DNA linkers melting point
The researchers determined that the length of DNA connected to each gold nanoparticle can t be much longer than the size of the nanoparticle.
In the study the gold nanoparticles varied from five to 20 nanometers in diameter; for each the DNA length that led to crystal formation was about 18 base pairs and six single-base ticky ends.?
For the battery project Chao added tiny nanoparticles of carbon to the polymer so it would conduct electricity. e found that silicon electrodes lasted 10 times longer
And because e-jet can naturally handle fluid inks it is suited exceptionally well for patterning solution suspensions of nanotubes nanocrystals nanowires
Solar steam efficiency comes from light-harvesting nanoparticles that were created at LANP by Rice graduate student Oara Neumann,
but also help deliver lithium ions to the nanoparticles. Major hurdle Lab tests showed initial charge capacities of more than 1
Tour says. raphene nanoribbons make a terrific framework that keeps the tin oxide nanoparticles dispersed and keeps them from fragmenting during cycling,
the volume changes in the nanoparticles are not dramatic. NRS also provide a lightweight, conductive framework, with their high aspect ratios and extreme thinness.
Lin says the lab plans to build batteries with other metallic nanoparticles to test their cycling and storage capacities.
so scientists at Los alamos National Laboratory, New mexico, have been working on a mechanism that allows nanocrystalline materials to heal themselves after suffering radiation-induced damage.
The nanocrystalline materials the scientists have been working on are created those from nanosized particles, in this case from copper.
Nanocrystalline materials comprise a mixture of grains and the interface between those grains, called grain boundaries.
Nanocrystalline materials contain a large amount of grain boundaries which are thought to be able to absorb
But until conducting recent computer simulations, scientists lacked the ability to predict the performance of nanocrystalline materials in extreme environments.
the researchers describe a newly discovered oading-unloadingphenomenon at grain boundaries in nanocrystalline materials, which allows for effective self-healing of radiation-induced defects.
#Scientists find that exposure to nanoparticles could impact cardiovascular health Due to its huge potential in applications ranging from cheaper vaccinations to energy-storing car panels there's plenty of excitement surrounding the emergence of nanotechnology.
But a team of scientists are urging caution with a study conducted at the Technion-Israel Institute of technology suggesting that exposure to silicon-based nanoparticles may play a role in the development of cardiovascular disease.
exposing them to nanoparticles made from silicon dioxide. The team was seeking to explore the effects that the nanoparticles have on the development of atherosclerosis a condition that leads to the hardening of the arteries and cardiovascular events such as heart attack and stroke.
What the researchers found was a negative relationship between the silicon-based nanoparticles and macrophages a type of white blood cell that destroys damaged or dead cells.
The toxicity of the nanoparticles causes the macrophages to transform into foam cells or lipids leading to the development of lesions and hastening the onset of atherosclerosis.
This exposure may be especially chronic for those employed in research laboratories and in high tech industry where workers handle manufacture use
and dispose of nanoparticles says the study's lead author Professor Michael Aviram. Products that use silica-based nanoparticles for biomedical uses such as various chips drug or gene delivery and tracking imaging ultrasound therapy and diagnostics may also pose an increased cardiovascular
risk for consumers as well. This study isn't the first time concerns have been raised about the dangers of nanotechnology.
Previous research has turned up some unsettling results including that silver nanoparticles can materially alter a person's immunity and that titanium dioxide nanoparticles cause systemic genetic damage in mice.
and interaction of silica-based nanoparticles with biological systems write the researchers. Because our research demonstrates a clear cardiovascular health risk associated with this trend steps need to be taken to help ensure that potential health
such as"ninja polymers"and artificial nanoparticles made of lipids. But this latest breakthrough by researchers from Novobiotic in Cambridge, Massachusetts, Northeastern University in Boston, the University of Bonn in Germany,
#Gelatin Nanoparticles could Deliver Drugs to your Brain Stroke victims could have more time to seek treatment that could reduce harmful effects on the brain thanks to tiny blobs of gelatin that could deliver the medication to the brain non-invasively.
nanoparticles in the journal Drug Delivery and Translational Research. The researchers found that gelatin nanoparticles could be laced with medications for delivery to the brain
and that they could extend the treatment window for when a drug could be effective.
Once administered the gelatin nanoparticles target damaged brain tissue thanks to an abundance of gelatin-munching enzymes produced in injured regions.
Illinois professor Kyekyoon#Kevin#Kim graduate student Elizabeth Joachim and researchscientist Hyungsoo Choi developed tiny gelatin nanoparticles that can carry medicationto the brain which could lead to longer
#To test gelatin nanoparticles as a drug-delivery system the researchers used the drug osteopontin (OPN)
By lacing gelatin nanoparticles with OPN the researchers found that they could extend the treatment window in rats so much
so that treating a rat with nanoparticles six hours after a stroke showed the same efficacy rate as giving them OPN alone after one hour#70 percent recovery of dead volume in the brain.
The researchers hope the gelatin nanoparticles administered through the nasal cavity can help deliver other drugs to more effectively treat a variety of brain injuries and neurological diseases.#
#Gelatin nanoparticles are a delivery vehicle that could be used to deliver many therapeutics to the brain#Choi said.#
Before coming to Harvard from the University of Illinois at Urbana-Champaign last year, Lewis had spent more than a decade developing 3-D printing techniques using ceramics, metal nanoparticles, polymers,
In this case, the researchers chose peptides that could capture gold nanoparticles and quantum dots. Researchers then programmed the E coli cells to produce biofilms with the conducting properties of gold nanowires.
Our electronic whiskers consist of high-aspect-ratio elastic fibers coated with conductive composite films of nanotubes and nanoparticles.
and silver nanoparticles that are patterned on high-aspect-ratio elastic fibers. The nanotubes provide both flexibility allowing the whiskers to bend
and nanoparticles they're also printing with dough vegetables and even meats. Both engineers and gourmet chefs are experimenting with creating foods from 3-D printing.
When turned on, electrons flow single-file through each double quantum dot which causes them to emit photons in the microwave region of the spectrum.
"The double quantum dot allows them full control over the motion of even a single electron,
Diamond nanocrystals immersed in a cell's cytoplasm could essentially produce real-time films of the activity of single molecules,
The researchers fabricated their samples from round nanoparticles of boron nitride in which the atoms of nitrogen and boron form an onionlike structure of nested layers.
the nanoparticles coalesced into tiny grains comprising numerous twin domains. The onionlike precursors, Tian explains,
it s the quantum dot TV! Researchers working with nanoscale fluorescent particles called quantum dots have predicted long groundbreaking achievements,
Demand for quantum dot displays, say industry watchers, could benefit quantum dot companies, bring down the price of these nanomaterials
and boost other applications that have stalled.""Displays are a potential market that could help quantum dot companies find traction,
says Jonathan Melnick, an analyst at Lux Research in Boston, Massachusetts. Quantum dots are crystals about 10 nano#metres in diameter,
researchers can tune the precise colour a quantum dot will absorb and re-emit by tailoring its size.
That was when the Quantum dot Corporation of Hayward, California, began selling them to cell biologists, who prize them as fluorescent imaging labels for proteins and other biological molecules.
As recently as 2010, the biomedical sector was responsible for US$48#million of $67#million in total quantum dot revenues, according to BCC Research of Wellesley, Massachusetts.
with quantum dot coatings to convert the harsh glare of LEDS into a warmer glow, to make them more appealing as long-life, low energy light bulbs.
and technology for the light-bulb market evolved too fast for the quantum dot coatings to keep up."
His optimism will be tested this spring with the company s quantum dot debut in Sony LCD televisions,
Another quantum dot company, Nanosys of Palo alto, California, is providing 3m of St paul, Minnesota, with material for a similar product. 3m will make a polymer film seeded with quantum dots that does the same jobas QD Vision s glass tube.
will make up $310#million of a total $666 million in quantum dot revenues. Melnick says that these numbers might be overly optimistic,
#Stealth nanoparticles sneak past immune system s defences Small man-made peptides can help to sneak drug-bearing nanobeads past the ever-vigilant immune system,
Although scientists are developing nanoparticles that help to deliver drugs to the right place, all therapeutic molecules face a deadly foe#the immune system.
Researchers at the University of Pennsylvania in Philadelphia have now found a way to stop macrophages from destroying drug-bearing nanoparticles.
Nanoparticles tend to accumulate in tumours because of the tumour s haphazard structure and leaky blood vessels.
The nanoparticles spill through these blood vessels and get stuck in the tumour. Buoyed by the evidence that the peptide-carrying nanobeads were circulating in the blood
If the semiconductor is small enough#a nanoparticle, for example#a single electron can switch the transistor on,
They strung together thousands of gold nanoparticles, each 10 nanometres across, into long necklaces. These can form a tangled network that connects two electrodes some 30 micrometres apart.
Roughly 5%of the gold nanoparticles have defects that prevent current from flowing from one electrode to the other.
But if an electron settles on a defective nanoparticle it makes it slightly easier for current to flow,
#'Wi-fi'Nanoparticles Send Signals from the Brain The problem with talking to our own brains,
A medical research team at Florida International University in Miami injected 20 billion nanoparticles into the brains of mice
the electric field can directly couple to the electric circuitry of the neural network. he nanoparticles could be used to deliver drugs to specific parts of the brain.
the nanoparticles could generate measurable magnetic fields in response to the brain electrical fields. Toggle the system back
Gold nanoparticles Could Detect Disease: Discovery Newsprevious studies have shown that diseases such as lung and esophageal cancer,
it will probably be thanks to MIT spinout QD Vision, a pioneer of quantum dot television displays.
Quantum dots are light-emitting semiconductor nanocrystals that can be tuned by changing their size, nanometer by nanometer to emit all colors across the visible spectrum.
Last June, Sony used QD Vision product, called Color IQ, in millions of its Bravia riluminostelevisions, marking the first-ever commercial quantum dot display.
and others developed a pioneering technique for producing quantum dot LEDS (QLEDS). To do so, they sandwiched a layer of quantum dots, a few nanometers thick, between two organic thin films.
became a landmark in the quantum dot-devices field. oon venture capitalists were calling Vladimir, asking if we spin a company out,
quantum dot displays. aking a transition like that from lighting to displays tests the nerves of folks involved, from top to bottom,
and last year became the first to market with a quantum dot display. Today, QD Vision remains one of only two quantum dot display companies that have seen their products go to market.
Now, with a sharp rise in commercial use, quantum dot technologies are positioned to penetrate the display industry
Coe-Sullivan says. Along with Color IQ-powered LCD TVS, Amazon released a quantum dot Kindle last year,
and Asus has a quantum dot notebook. nd there nothing in between that quantum dots can address,
he says. In the future, Coe-Sullivan adds, QD Vision may even go back and tackle its first challenge:
and value proposition for quantum dot lighting. n
#Hewlett Foundation funds new MIT initiative on cybersecurity policy MIT has received $15 million in funding from the William
#Two sensors in one MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals.
The researchers found that their imaging particles accumulated in the liver as nanoparticles usually do.
They have created also nanoparticles carrying the fluorescent agent plus up to three different drugs. This allows them to track
whether the nanoparticles are delivered to their targeted locations. That s the advantage of our platform we can mix
#Nanoparticles get a magnetic handle A long-sought goal of creating particles that can emit a colorful fluorescent glow in a biological environment
The new technology could make it possible to track the position of the nanoparticles as they move within the body or inside a cell.
At the same time the nanoparticles could be manipulated precisely by applying a magnetic field to pull them along. And finally the particles could have a coating of a bioreactive substance that could seek out
All of these goals are achieved by the new nanoparticles which can be identified with great precision by the wavelength of their fluorescent emissions.
and postdoc Ou Chen the nanoparticles crystallize such that they self-assemble in exactly the way that leads to the most useful outcome:
That puts the fluorescent molecules in the most visible location for allowing the nanoparticles to be tracked optically through a microscope.
because the starting material fluorescent nanoparticles that Bawendi and his group have been perfecting for years are themselves perfectly uniform in size.
The next step for the team is to test the new nanoparticles in a variety of biological settings.
Christopher Murray a professor of chemistry and materials science and engineering at the University of Pennsylvania who was connected not with this research says This work exemplifies the power of using nanocrystals as building blocks for multiscale and multifunctional structures.
For this study Yanik s team developed a new technology to inject RNA carried by nanoparticles called lipidoids previously designed by Daniel Anderson an associate professor of chemical engineering member of the Koch Institute for Integrative Cancer Research and Institute
#The ability to identify useful drug delivery nanoparticles using this miniaturized system holds great potential for accelerating our discovery process Anderson says.
and tumor-suppressor gene p53 is deleted researchers injected mice with RNA-carrying nanoparticles. This mouse model reflects many of the hallmarks of human lung cancer
The nanoparticles are made of a small polymer lipid conjugate; unlike liver-targeting nanoparticles these preferentially target the lung
and are tolerated well in the body. They were developed in the laboratories of co-senior author Daniel G. Anderson the Samuel A. Goldblith Associate professor of Chemical engineering an affiliate of MIT's Institute of Medical Engineering and Science;
In this study researchers tested the nanoparticle-delivery system with different payloads of therapeutic RNA. They found that delivery of mir-34a a p53-regulated mirna slowed tumor growth as did delivery of sikras a KRAS-targeting sirna.
Next researchers treated mice with both mir-34a and sikras in the same nanoparticle. Instead of just slowing tumor growth this combination therapy caused tumors to regress
treatment#with nanoparticles carrying both mir-34a and sikras; and treatment#with both cisplatin and the nanoparticles.
They found that the nanoparticle treatment extended life just as well as the cisplatin treatment and furthermore that the combination therapy of the nanoparticles and cisplatin together extended life by about an additional 25 percent.
Potential for personalized cancer treatmentsthis early example of RNA combination therapy demonstrates the potential of developing personalized cancer treatments.
We took the best mouse model for lung cancer we could find we found the best nanoparticle we could use
However nanoparticles and other delivery methods now being developed for DNA and RNA could prove more effective in targeting other organs Sharp says.
The latter approach involves mixing water with nanoparticles that heat up quickly when exposed to sunlight, vaporizing the surrounding water molecules as steam.
in part because it is a natural destination for nanoparticles. But now, in a study appearing in the May 11 issue of Nature Nanotechnology,
Using nanoparticles designed and screened for endothelial delivery of short strands of RNA called sirna,
Anderson and Langer have developed previously nanoparticles, now in clinical development, that can deliver sirna to liver cells called hepatocytes by coating the nucleic acids in fatty materials called lipidoids.
because they resemble the fatty droplets that circulate in the blood after a high-fat meal is consumed. he liver is a natural destination for nanoparticles,
if you inject nanoparticles into the blood, they are likely to end up there. Scientists have had some success delivering RNA to nonliver organs
they did not enter liver hepatocytes. hat interesting is that by changing the chemistry of the nanoparticle you can affect delivery to different parts of the body,
the researchers used the nanoparticles to block two genes that have been implicated in lung cancer VEGF receptor 1 and Dll4,
which relies on a nanoparticle that carries two drugs and releases them at different times,
who is a member of MIT Koch Institute for Integrative Cancer Research. ee moving from the simplest model of the nanoparticle just getting the drug in there
and targeting it to having smart nanoparticles that deliver drug combinations in the way that you need to really attack the tumor.
a chemical engineer who has designed previously several types of nanoparticles that can carry two drugs at once.
Furthermore, packaging the two drugs in liposome nanoparticles made them much more effective than the traditional forms of the drugs,
At the same time, Hammond lab is working on more complex nanoparticles that would allow for more precise loading of the drugs
and fine-tuning of their staggered release. ith a nanoparticle delivery platform that allows us to control the relative rates of release and the relative amounts of loading,
contain colored stripes of nanocrystals that glow brightly when lit up with near-infrared light. These particles can easily be manufactured
and include several stripes of different colored nanocrystals, known as are earth upconverting nanocrystals. These crystals are doped with elements such as ytterbium, gadolinium, erbium,
and thulium, which emit visible colors when exposed to near-infrared light. By altering the ratios of these elements,
In this case, each polymer stream contains nanocrystals that emit different colors, allowing the researchers to form striped particles.
So far, the researchers have created nanocrystals in nine different colors, but it should be possible to create many more,
and youl never get the same combination. he use of these upconverting nanocrystals is quite clever and highly enabling,
and more efficient including targeted nanoparticles. Wen Xue a senior postdoc at the Koch Institute is also a lead author of the paper.
and other substances including living cells MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials such as gold nanoparticles and quantum dots.
These peptides can capture nonliving materials such as gold nanoparticles incorporating them into the biofilms. By programming cells to produce different types of curli fibers under certain conditions the researchers were able to control the biofilms properties
If gold nanoparticles are added to the environment the histidine tags will grab onto them creating rows of gold nanowires and a network that conducts electricity.
along with the bacteria that produce histidine-tagged fibers resulting in a material that contains both quantum dots and gold nanoparticles.
the researchers embedded them with cerium oxide nanoparticles, also known as nanoceria. These particles are very strong antioxidants that scavenge oxygen radicals
and used a technique called vascular infusion to deliver nanoparticles into Arabidopsis thaliana, a small flowering plant.
the researchers applied a solution of nanoparticles to the underside of the leaf, where it penetrated tiny pores known as stomata,
What is the impact of nanoparticles on the production of chemical fuels like glucose? Giraldo says.
a professor of biomedical engineering at Boston University who was involved not in the research. he authors nicely show that self-assembling nanoparticles can be used to enhance the photosynthetic capacity of plants,
and Howard hughes medical institute investigator Sangeeta Bhatia relies on nanoparticles that interact with tumor proteins called proteases each
The MIT nanoparticles are coated with peptides (short protein fragments) targeted by different MMPS. These particles congregate at tumor sites where MMPS cleave hundreds of peptides
With the current version of the technology patients would first receive an injection of the nanoparticles then urinate onto the paper test strip.
To make the process more convenient the researchers are now working on a nanoparticle formulation that could be implanted under the skin for longer-term monitoring.
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