| Gold nanoparticle (94) |  |
| Inorganic nanoparticle (12) | |
| Magnetic nanoparticle (35) | |
| Metal nanoparticle (49) | |
| Nanocrystal (322) | |
| Nanodisk (9) | |
| Nanogel (7) | |
| Nanoparticle (1347) | |
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| Oxide nanoparticle (15) | |
| Silver nanoparticle (40) | |
| Zinc oxide nanoparticle (7) | |
the partners incorporated nanoparticles and micro-or nano-sized pigments into coatings and surface layers. e implemented this technology for three types of material:
and enhance the efficiency of the treatment. he decorating of nanoparticles very tiny particles with cyclodextrins allows us to play with the functionality,
A decorated approach Dr Yannakopoulou says that progress in delivery efficiency has already been made through decorating nanoparticles with cyclodextrins combined with nhanced Permeability and Retention EPR) the property by
and thus tend to accumulate in tumour tissue much more than they do in normal tissues. e have been able to play with the sizes of nanoparticles to make them big enough to get into the tumour cells,
'This innovation allows nanoparticles to be incorporated and evenly dispersed in a polymer mould in a very low proportion.
and other goods. The Flexpakrenew research team developed a number of new techniques that use renewable materials reinforced with nanoparticles and innovative coatings.
##The shoebox-sized prototype diagnostic device known as the single particle interferometric reflectance imaging sensor (SP-IRIS) detects pathogens by shining light from multicolor LED sources on viral nanoparticles bound to the sensor surface by a coating
and can capture the telltale responses of up to a million nanoparticles. In collaboration with BD Technologies and Nexgen Arrays a start-up based at the Photonics Center
and nanoparticles can be used to image live cells. To study the channels the team engineered variants of tarantula toxin that could be labeled fluorescently
The technology uses aluminum nanoparticles to create the vivid red blue and green hues found in today s top-of-the-line LCD televisions and monitors.
the phosphorous acid reduces the copper ions to copper nanoparticles. The nanoparticles attract electrons from the silicon wafer surface,
oxidizing it and allowing hydrogen fluoride to burn inverted pyramid-shaped nanopores into the silicon. Fine-tuning the process resulted in a black silicon layer with pores as small as 590 nanometers (billionths of a meter) that let through more than 99 percent of light.
University of Toronto rightoriginal Studyposted by Marit Mitchell-Toronto on June 9 2014those flat glassy solar panels on your neighborâ#roof may be getting a more efficient makeover thanks to a new class of solar-sensitive nanoparticles.
This new form of solid stable light-sensitive nanoparticles called colloidal quantum dots could lead to cheaper and more flexible solar cells as well as better gas sensors infrared lasers infrared light emitting diodes and more.
and then used it to move nanoparticles of cadmium disulfide along the length of a nanotube.
The nanoparticle is fluorescent in visible light and the nanotubes are fluorescent in the near-infrared.
#DNA helps nanoparticle crystals self-assemble Northwestern University rightoriginal Studyposted by Megan Fellman-Northwestern on December 2 2013using the same structure found in nature researchers have built the first near-perfect single crystals
Given a set of nanoparticles and a specific type of DNA Olvera de la Cruz showed they can accurately predict the 3d structure
The researchers determined that the ratio of the DNA linker s length to the size of the nanoparticle is critical. f you get the right ratio it makes a perfect crystalâ##isn t that fun?
Working with approximately 1 million nanoparticles in water they heated the solution to a temperature just above the DNA linkers melting point
The researchers determined that the length of DNA connected to each gold nanoparticle can t be much longer than the size of the nanoparticle.
For the battery project Chao added tiny nanoparticles of carbon to the polymer so it would conduct electricity. e found that silicon electrodes lasted 10 times longer
Solar steam efficiency comes from light-harvesting nanoparticles that were created at LANP by Rice graduate student Oara Neumann,
but also help deliver lithium ions to the nanoparticles. Major hurdle Lab tests showed initial charge capacities of more than 1
Tour says. raphene nanoribbons make a terrific framework that keeps the tin oxide nanoparticles dispersed and keeps them from fragmenting during cycling,
the volume changes in the nanoparticles are not dramatic. NRS also provide a lightweight, conductive framework, with their high aspect ratios and extreme thinness.
#Scientists find that exposure to nanoparticles could impact cardiovascular health Due to its huge potential in applications ranging from cheaper vaccinations to energy-storing car panels there's plenty of excitement surrounding the emergence of nanotechnology.
But a team of scientists are urging caution with a study conducted at the Technion-Israel Institute of technology suggesting that exposure to silicon-based nanoparticles may play a role in the development of cardiovascular disease.
exposing them to nanoparticles made from silicon dioxide. The team was seeking to explore the effects that the nanoparticles have on the development of atherosclerosis a condition that leads to the hardening of the arteries and cardiovascular events such as heart attack and stroke.
What the researchers found was a negative relationship between the silicon-based nanoparticles and macrophages a type of white blood cell that destroys damaged or dead cells.
The toxicity of the nanoparticles causes the macrophages to transform into foam cells or lipids leading to the development of lesions and hastening the onset of atherosclerosis.
This exposure may be especially chronic for those employed in research laboratories and in high tech industry where workers handle manufacture use
and dispose of nanoparticles says the study's lead author Professor Michael Aviram. Products that use silica-based nanoparticles for biomedical uses such as various chips drug or gene delivery and tracking imaging ultrasound therapy and diagnostics may also pose an increased cardiovascular
risk for consumers as well. This study isn't the first time concerns have been raised about the dangers of nanotechnology.
Previous research has turned up some unsettling results including that silver nanoparticles can materially alter a person's immunity and that titanium dioxide nanoparticles cause systemic genetic damage in mice.
and interaction of silica-based nanoparticles with biological systems write the researchers. Because our research demonstrates a clear cardiovascular health risk associated with this trend steps need to be taken to help ensure that potential health
such as"ninja polymers"and artificial nanoparticles made of lipids. But this latest breakthrough by researchers from Novobiotic in Cambridge, Massachusetts, Northeastern University in Boston, the University of Bonn in Germany,
#Gelatin Nanoparticles could Deliver Drugs to your Brain Stroke victims could have more time to seek treatment that could reduce harmful effects on the brain thanks to tiny blobs of gelatin that could deliver the medication to the brain non-invasively.
nanoparticles in the journal Drug Delivery and Translational Research. The researchers found that gelatin nanoparticles could be laced with medications for delivery to the brain
and that they could extend the treatment window for when a drug could be effective.
Once administered the gelatin nanoparticles target damaged brain tissue thanks to an abundance of gelatin-munching enzymes produced in injured regions.
Illinois professor Kyekyoon#Kevin#Kim graduate student Elizabeth Joachim and researchscientist Hyungsoo Choi developed tiny gelatin nanoparticles that can carry medicationto the brain which could lead to longer
#To test gelatin nanoparticles as a drug-delivery system the researchers used the drug osteopontin (OPN)
By lacing gelatin nanoparticles with OPN the researchers found that they could extend the treatment window in rats so much
so that treating a rat with nanoparticles six hours after a stroke showed the same efficacy rate as giving them OPN alone after one hour#70 percent recovery of dead volume in the brain.
The researchers hope the gelatin nanoparticles administered through the nasal cavity can help deliver other drugs to more effectively treat a variety of brain injuries and neurological diseases.#
#Gelatin nanoparticles are a delivery vehicle that could be used to deliver many therapeutics to the brain#Choi said.#
Our electronic whiskers consist of high-aspect-ratio elastic fibers coated with conductive composite films of nanotubes and nanoparticles.
and nanoparticles they're also printing with dough vegetables and even meats. Both engineers and gourmet chefs are experimenting with creating foods from 3-D printing.
The researchers fabricated their samples from round nanoparticles of boron nitride in which the atoms of nitrogen and boron form an onionlike structure of nested layers.
the nanoparticles coalesced into tiny grains comprising numerous twin domains. The onionlike precursors, Tian explains,
#Stealth nanoparticles sneak past immune system s defences Small man-made peptides can help to sneak drug-bearing nanobeads past the ever-vigilant immune system,
Although scientists are developing nanoparticles that help to deliver drugs to the right place, all therapeutic molecules face a deadly foe#the immune system.
Researchers at the University of Pennsylvania in Philadelphia have now found a way to stop macrophages from destroying drug-bearing nanoparticles.
Nanoparticles tend to accumulate in tumours because of the tumour s haphazard structure and leaky blood vessels.
The nanoparticles spill through these blood vessels and get stuck in the tumour. Buoyed by the evidence that the peptide-carrying nanobeads were circulating in the blood
If the semiconductor is small enough#a nanoparticle, for example#a single electron can switch the transistor on,
But if an electron settles on a defective nanoparticle it makes it slightly easier for current to flow,
#'Wi-fi'Nanoparticles Send Signals from the Brain The problem with talking to our own brains,
A medical research team at Florida International University in Miami injected 20 billion nanoparticles into the brains of mice
the electric field can directly couple to the electric circuitry of the neural network. he nanoparticles could be used to deliver drugs to specific parts of the brain.
the nanoparticles could generate measurable magnetic fields in response to the brain electrical fields. Toggle the system back
#Two sensors in one MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals.
The researchers found that their imaging particles accumulated in the liver as nanoparticles usually do.
They have created also nanoparticles carrying the fluorescent agent plus up to three different drugs. This allows them to track
whether the nanoparticles are delivered to their targeted locations. That s the advantage of our platform we can mix
#Nanoparticles get a magnetic handle A long-sought goal of creating particles that can emit a colorful fluorescent glow in a biological environment
The new technology could make it possible to track the position of the nanoparticles as they move within the body or inside a cell.
At the same time the nanoparticles could be manipulated precisely by applying a magnetic field to pull them along. And finally the particles could have a coating of a bioreactive substance that could seek out
All of these goals are achieved by the new nanoparticles which can be identified with great precision by the wavelength of their fluorescent emissions.
and postdoc Ou Chen the nanoparticles crystallize such that they self-assemble in exactly the way that leads to the most useful outcome:
That puts the fluorescent molecules in the most visible location for allowing the nanoparticles to be tracked optically through a microscope.
because the starting material fluorescent nanoparticles that Bawendi and his group have been perfecting for years are themselves perfectly uniform in size.
The next step for the team is to test the new nanoparticles in a variety of biological settings.
For this study Yanik s team developed a new technology to inject RNA carried by nanoparticles called lipidoids previously designed by Daniel Anderson an associate professor of chemical engineering member of the Koch Institute for Integrative Cancer Research and Institute
#The ability to identify useful drug delivery nanoparticles using this miniaturized system holds great potential for accelerating our discovery process Anderson says.
and tumor-suppressor gene p53 is deleted researchers injected mice with RNA-carrying nanoparticles. This mouse model reflects many of the hallmarks of human lung cancer
The nanoparticles are made of a small polymer lipid conjugate; unlike liver-targeting nanoparticles these preferentially target the lung
and are tolerated well in the body. They were developed in the laboratories of co-senior author Daniel G. Anderson the Samuel A. Goldblith Associate professor of Chemical engineering an affiliate of MIT's Institute of Medical Engineering and Science;
In this study researchers tested the nanoparticle-delivery system with different payloads of therapeutic RNA. They found that delivery of mir-34a a p53-regulated mirna slowed tumor growth as did delivery of sikras a KRAS-targeting sirna.
Next researchers treated mice with both mir-34a and sikras in the same nanoparticle. Instead of just slowing tumor growth this combination therapy caused tumors to regress
treatment#with nanoparticles carrying both mir-34a and sikras; and treatment#with both cisplatin and the nanoparticles.
They found that the nanoparticle treatment extended life just as well as the cisplatin treatment and furthermore that the combination therapy of the nanoparticles and cisplatin together extended life by about an additional 25 percent.
Potential for personalized cancer treatmentsthis early example of RNA combination therapy demonstrates the potential of developing personalized cancer treatments.
We took the best mouse model for lung cancer we could find we found the best nanoparticle we could use
However nanoparticles and other delivery methods now being developed for DNA and RNA could prove more effective in targeting other organs Sharp says.
The latter approach involves mixing water with nanoparticles that heat up quickly when exposed to sunlight, vaporizing the surrounding water molecules as steam.
in part because it is a natural destination for nanoparticles. But now, in a study appearing in the May 11 issue of Nature Nanotechnology,
Using nanoparticles designed and screened for endothelial delivery of short strands of RNA called sirna,
Anderson and Langer have developed previously nanoparticles, now in clinical development, that can deliver sirna to liver cells called hepatocytes by coating the nucleic acids in fatty materials called lipidoids.
because they resemble the fatty droplets that circulate in the blood after a high-fat meal is consumed. he liver is a natural destination for nanoparticles,
if you inject nanoparticles into the blood, they are likely to end up there. Scientists have had some success delivering RNA to nonliver organs
they did not enter liver hepatocytes. hat interesting is that by changing the chemistry of the nanoparticle you can affect delivery to different parts of the body,
the researchers used the nanoparticles to block two genes that have been implicated in lung cancer VEGF receptor 1 and Dll4,
which relies on a nanoparticle that carries two drugs and releases them at different times,
who is a member of MIT Koch Institute for Integrative Cancer Research. ee moving from the simplest model of the nanoparticle just getting the drug in there
a chemical engineer who has designed previously several types of nanoparticles that can carry two drugs at once.
Furthermore, packaging the two drugs in liposome nanoparticles made them much more effective than the traditional forms of the drugs,
At the same time, Hammond lab is working on more complex nanoparticles that would allow for more precise loading of the drugs
and more efficient including targeted nanoparticles. Wen Xue a senior postdoc at the Koch Institute is also a lead author of the paper.
and used a technique called vascular infusion to deliver nanoparticles into Arabidopsis thaliana, a small flowering plant.
the researchers applied a solution of nanoparticles to the underside of the leaf, where it penetrated tiny pores known as stomata,
What is the impact of nanoparticles on the production of chemical fuels like glucose? Giraldo says.
a professor of biomedical engineering at Boston University who was involved not in the research. he authors nicely show that self-assembling nanoparticles can be used to enhance the photosynthetic capacity of plants,
and Howard hughes medical institute investigator Sangeeta Bhatia relies on nanoparticles that interact with tumor proteins called proteases each
The MIT nanoparticles are coated with peptides (short protein fragments) targeted by different MMPS. These particles congregate at tumor sites where MMPS cleave hundreds of peptides
With the current version of the technology patients would first receive an injection of the nanoparticles then urinate onto the paper test strip.
To make the process more convenient the researchers are now working on a nanoparticle formulation that could be implanted under the skin for longer-term monitoring.
scientists have tried targeting them to lymph nodes using nanoparticles to deliver them, or tagging them with antibodies specific to immune cells in the lymph nodes.
#Creating synthetic antibodies MIT chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds
The noninvasive diagnostic described in a recent issue of the journal ACS Nano relies on nanoparticles that detect the presence of thrombin a key blood-clotting factor.
which is an injectable nanoparticle and made it a thrombin sensor. The system consists of iron oxide nanoparticles
After being injected into mice the nanoparticles travel throughout the body. When the particles encounter thrombin the thrombin cleaves the peptides at a specific location releasing fragments that are excreted then in the animals urine.
Through application of the nanoparticles if proven well-tolerated and nontoxic alterations in the normal low levels of physiological thrombin generation might be detected easily says Spronk who was not part of the research team.
Among nanomaterials, carbon-based nanoparticles such as carbon nanotubes and graphene have shown promising results, but they suffer from relatively low electrical conductivity,
are not unique to carbon-based nanoparticles, and that niobium nanowire yarn is a promising an alternative. magine youe got some kind of wearable health-monitoring system,
#New study shows how nanoparticles can clean up environmental pollutants Many human-made pollutants in the environment resist degradation through natural processes,
researchers from MIT and the Federal University of Goiás in Brazil demonstrate a novel method for using nanoparticles
They initially sought to develop nanoparticles that could be used to deliver drugs to cancer cells. Brandl had synthesized previously polymers that could be cleaved apart by exposure to UV LIGHT.
Nanoparticles made from these polymers have a hydrophobic core and a hydrophilic shell. Due to molecular-scale forces
in a solution hydrophobic pollutant molecules move toward the hydrophobic nanoparticles, and adsorb onto their surface,
according to the researchers, was confirming that small molecules do indeed adsorb passively onto the surface of nanoparticles. o the best of our knowledge,
it is the first time that the interactions of small molecules with preformed nanoparticles can be measured directly,
we showed in a system that the adsorption of small molecules on the surface of the nanoparticles can be used for extraction of any kind,
#One nanoparticle six types of medical imaging It's technology so advanced that the machine capable of using it doesn't yet exist.
University at Buffalo researchers and their colleagues have designed a nanoparticle that can be detected by six medical imaging techniques:
In the future, patients could receive a single injection of the nanoparticles to have all six types of imaging done.
"This nanoparticle may open the door for new'hypermodal'imaging systems that allow a lot of new information to be obtained using just one contrast agent,
"When Lovell and colleagues used the nanoparticles to examine the lymph nodes of mice, they found that CT
One nanoparticle, 6 types of medical imaging This transmission electron microscopy image shows the nanoparticles, which consist of a core that glows blue
The research, Hexamodal Imaging with Porphyrin-Phospholipid-Coated Upconversion Nanoparticles, was published online Jan 14 in the journal Advanced Materials.
The researchers designed the nanoparticles from two components: An"upconversion"core that glows blue when struck by near-infrared light,
"Combining these two biocompatible components into a single nanoparticle could give tomorrow's doctors a powerful,
whether the nanoparticle is safe to use for such purposes, but it does not contain toxic metals such as cadmium that are known to pose potential risks
and found in some other nanoparticles.""""Another advantage of this core/shell imaging contrast agent is that it could enable biomedical imaging at multiple scales, from single-molecule to cell imaging,
#Nanoparticles for clean drinking water One way of removing harmful nitrate from drinking water is to catalyse its conversion to nitrogen.
By using palladium nanoparticles as a catalyst, and by carefully controlling their size, this drawback can be eliminated partially.
This has resulted in palladium nanoparticles that can catalyse the conversion to nitrogen while producing very little ammonia.
which is entitled"Colloidal Nanoparticles as Catalysts and Catalyst Precursors for Nitrite Hydrogenation"on Thursday 15 january a
and bimetallic film over nanoparticles, a planar substrate for enhancing SERS signals. Together these technologies help to overcome interfering signals from the matrix background such as proteins in urine.
The bimetallic film over nanoparticles is coated also with osmium carbonyl clusters to which target-seeking antibodies can be conjugated for assaying A1at (see image).
#Researchers find exposure to nanoparticles may threaten heart health Nanoparticles extremely tiny particles measured in billionths of a meter are increasingly everywhere and especially in biomedical products.
but now a team of Israeli scientists has for the first time found that exposure nanoparticles (NPS) of silicon dioxide (Sio2) can play a major role in the development of cardiovascular diseases
and the Center of Excellence in Exposure Science and Environmental Health (TCEEH Environmental exposure to nanoparticles is becoming unavoidable due to the rapid expansion of nanotechnology says the study's lead author Prof.
and dispose of nanoparticles. Products that use silica-based nanoparticles for biomedical uses such as various chips drug or gene delivery and tracking imaging ultrasound therapy and diagnostics may also pose an increased cardiovascular
risk for consumers as well. In this study researchers exposed cultured laboratory mouse cells resembling the arterial wall cells to NPS of silicon dioxide
The aims of our study were to gain additional insight into the cardiovascular risk associated with silicon dioxide nanoparticle exposure
We also wanted to use nanoparticles as a model for ultrafine particle (UFP) exposure as cardiovascular disease risk factors.
Here researchers have discovered for the first time that the toxicity of silicon dioxide nanoparticles has a significant and substantial effect on the accumulation of triglycerides in the macrophages at all exposure concentrations analyzed
This reality leads to increased human exposure and interaction of silica-based nanoparticles with biological systems.
#Arming nanoparticles for cancer diagnosis and treatment UCD researchers have manipulated successfully nanoparticles to target two human breast cancer cell lines as a tool in cancer diagnosis and treatment.
Coating nanoparticles with different substances allows their interaction with cells to be tuned in a particular way.
For example using an optically active particle like gold (Au) will provide excellent contrast in near infrared (NIR) imaging
#'Trojan horse'proteins are step forward for nanoparticle-based anticancer and anti-dementia therapeutic approaches Scientists at Brunel University London have found a way of targeting hard-to-reach cancers
and degenerative diseases using nanoparticles but without causing the damaging side effects the treatment normally brings.
In a huge step forward in the use of nanomedicine the research helped discover proteins in the blood that disguise nanoparticles
Two studies Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages and Complement deposition on nanoparticles can modulate immune responses by macrophage B
This suggests that either coating nanoparticles or healthy tissue with complement proteins could reduce tissue damage
Using the data from this study carbon nanoparticles coated with genetically-engineered proteins are being used to target glioblastoma the most aggressive form of brain tumour.
By using a protein recognised by the immune system to effectively disguise carbon nanoparticles we will be able to deploy these tiny particles to target hard-to-reach areas without damaging side effects to the patient.
We used the quantum dots also known as nanoparticles as an ink Mcalpine said. We were able to generate two different colors orange and green.
For example it is not trivial to pattern a thin and uniform coating of nanoparticles and polymers without the involvement of conventional microfabrication techniques yet the thickness and uniformity of the printed films are two of the critical parameters that determine the performance
We're exploring the use of nanosphere materials other than polystyrene as well as nanoparticle shapes other than spheres Chang says.
#Atomic'mismatch'creates nano'dumbbells'Like snowflakes nanoparticles come in a wide variety of shapes and sizes.
The geometry of a nanoparticle is often as influential as its chemical makeup in determining how it behaves from its catalytic properties to its potential as a semiconductor component.
Thanks to a new study from the U s. Department of energy's (DOE) Argonne National Laboratory researchers are closer to understanding the process by which nanoparticles made of more than one material called heterostructured nanoparticles form.
Heterostructured nanoparticles can be used as catalysts and in advanced energy conversion and storage systems. Typically these nanoparticles are created from tiny seeds of one material on top of
which another material is grown. In this study the Argonne researchers noticed that the differences in the atomic arrangements of the two materials have a big impact on the shape of the resulting nanoparticle.
Before we started this experiment it wasn't entirely clear what's happening at the interface
In this study the researchers observed the formation of a nanoparticle consisting of platinum and gold.
Initially the gold covered the platinum seed's surface uniformly creating a type of nanoparticle known as core-shell.
As the gold continues to accumulate on one side of the seed nanoparticle small quantities slide down the side of the nanoparticle like grains of sand rolling down the side of a sand hill creating the dumbbell shape.
This is the first time anyone has been able to study the kinetics of this heterogeneous nucleation process of nanoparticles in real-time under realistic conditions said Argonne physicist Byeongdu Lee.
and the nanoscale which gave us a good view of how the nanoparticles form and transform.
This analysis of nanoparticle formation will help to lay the groundwork for the formation of new materials with different and controllable properties according to Shevchenko.
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