#Nanospheres shield chemo drugs, safely release high doses in response to tumor secretions Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize.
In mice treated with the nanoparticles coated with peptides that are impervious to MMPS or given saline,
similar to the working principle of a quantum dot gated by an external electrode. In our case, the charged atoms nearby provide the electrostatic gate potential that regulates the electron flow
But there is a substantial difference between a conventional semiconductor quantum dot comprising typically hundreds or thousands of atoms and the present case of a surface-bound molecule:
Piet Brouwer, a physicist at FUB and expert in quantum transport theory, said that his intriguing behavior goes beyond the established picture of charge transport through a gated quantum dot.
#Magnetic nanoparticles could be key to effective immunotherapy: New method moves promising strategy closer to clinical use Abstract:
Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use.
2015chemotherapeutic coatings enhance tumor-frying nanoparticles: Duke university researchers add a drug delivery mechanism to a nanoparticle therapy already proven to target,
heat and destroy tumors July 13th, 2015super graphene can help treat cancer July 10th, 2015govt. -Legislation/Regulation/Funding/Policy Researchers Build a Transistor from a Molecule and A few Atoms July 14th, 2015world first:
2015chemotherapeutic coatings enhance tumor-frying nanoparticles: Duke university researchers add a drug delivery mechanism to a nanoparticle therapy already proven to target,
heat and destroy tumors July 13th, 2015magnetic hyperthermia, an auxiliary tool in cancer treatments July 8th, 2015discoveries For faster,
2015grants/Awards/Scholarships/Gifts/Contests/Honors/Records Nanocrystalline Thin-film Solar cells July 15th, 2015better memory with faster lasers July 14th, 2015simpore, Uofr,
Ultrasonic waves are also the cause of the homogenous distribution of simultaneous charges of silver and nitrogen on the surfaces of zinc oxide nanoparticles.
LANP graduate student Bob Zheng and postdoctoral research associate Alejandro Manjavacas created a methodology that solar engineers can use to determine the electricity-producing potential for any arrangement of metallic nanoparticles.
including metallic nanoparticles that convert light into plasmons, waves of electrons that flow like a fluid across the particles'surface.
when you shine light on a metallic nanoparticle or nanostructure is that you can excite some subset of electrons in the metal to a much higher energy level,
The researchers report in Nano Letters that by combining inorganic semiconductor nanocrystals with organic molecules, they have succeeded in"upconverting"photons in the visible and near-infrared regions of the solar spectrum."
In their experiments, Bardeen and Tang worked with cadmium selenide and lead selenide semiconductor nanocrystals.
The cadmium selenide nanocrystals could convert visible wavelengths to ultraviolet photons, while the lead selenide nanocrystals could convert near-infrared photons to visible photons.
In lab experiments the researchers directed 980-nanometer infrared light at the hybrid material, which then generated upconverted orange yellow fluorescent 550-nanometer light,
The researchers were able to boost the upconversion process by up to three orders of magnitude by coating the cadmium selenide nanocrystals with organic ligands,
"The key to this research is the hybrid composite material--combining inorganic semiconductor nanoparticles with organic compounds.
and provided the nanocrystals. The UCR Office of Technology Commercialization has filed a provisional patent on the technology y
However, the heterogeneous distribution of nanoparticles in the structure of the membrane polymer can be considered as an important problem.
The surface of nanoparticles was coated with polystyrene sulfonate as a new approach to improve the homogenous distribution of nanoparticles in polymer.
This method significantly affects the distribution of nanoparticles in the membrane polymer and it modifies the structure and the separation performance.
#Perfect Optical Properties in Production of Aluminum oxide Colloid Nanoparticles Iranian researchers produced nanoparticles in forms of colloids which have very good optical properties and conserve their stability for a long time.
Perfect Optical Properties in Production of Aluminum oxide Colloid Nanoparticles Aluminum oxide colloid nanoparticles have applications in various fields
The large difference between surface and volume energy of nanoparticles is the cause of this problem.
These parameters in addition to other obstacles such as the creation of stable chemical complexes in an uncontrolled situation prevents the formation of alumina nanoparticles in form of colloid,
The produced nanoparticles have very high stability and appropriate optical properties and they can be used in the production of optical devices.
Taking into account the desirable optical properties of the produced nanoparticles, it is expected that an important step is taken in the development of nanotechnology in the field of medicine,
and obtaining mass-production of these nanoparticles. Results of the research have been published in Journal of the American Ceramic Society,
such as solutions made from metal nanoparticles. To make the ink, graphene flakes are mixed with a solvent,
A Transparent and Photoluminescent Foldable Nanocellulose/Quantum dot Paper")a new step toward bendable electronics. They have developed the first light-emitting, transparent and flexible paper out of environmentally friendly materials via a simple, suction-filtration method.
The dielectric separates the mirror with tiny metal nanoparticles randomly spaced at the top of the substrate.
The dielectric separates the mirror with tiny metal nanoparticles randomly spaced at the top of the substrate."
#Transient melting of a nanocrystal: seeing is believing (Nanowerk News) Jesse Clark, working as a postdoc in the LCN group of Ian Robinson,
has discovered a spectacular transient melting phenomenon in nanocrystals. Coherent X-ray diffraction experiments, carried out at the LCLS X-ray free electron laser facility at Stanford,
have allowed snapshot imaging of a single 300 nm gold nanocrystal in the picosecond time interval after the particle was excited with a laser.
and to reach the melting point about 50 ps later("Imaging transient melting of a nanocrystal using an X-ray laser").
Imaging transient melting of a nanocrystal using an x-ray laser. Snapshot projection images of a gold nanocrystal, 300nm across, before and after excitation with a femtosecond laser.
The second image, 50 picoseconds after excitation, displays a low density skin that returns to the original density at later times This result has significant implications beyond our basic understanding of the melting process.
#Surface-modified nanoparticles endow coatings with combined properties Fabricators and processors alike demand consistently high quality for their intermediate and final products.
The INM Leibniz Institute for New Materials uses nanoparticles as design element for such multifunctional coatings.
These nanoparticles are adapted specifically to the particular application by Small Molecule Surface Modification (SMSM. How this approach can be used to produce custom-tailored coatings will be demonstrated at the Techconnect World trade fair on 15 and 16 june in WASHINGTON DC, USA,
the nanoparticles used can be modified surface with organic moieties. Small Molecule Surface Modification (SMSM) bestows specific combinations of desired properties, for example hydrophilic, hydrophobic, adhesive, anti-adhesive
Nanoparticles thus modified are used to develop nanocomposites: they combine the physical solid-state properties of e g. ceramics or semiconductors with classic polymer-processing technology.
Titanium dioxide, barium titanate, indium-tin oxide or zirconium dioxide, for instance, are used as nanoparticles. In addition to the chemical intrinsic composition of the nanoparticles and their SMSM surface treatment, the properties that are attainable for the desired coatings also vary with the size and dispersal mode of the nanoparticles.
INM composite systems are produced via wet-chemical processes. The modified nanoparticles and additives combine with a polymer matrix (an epoxy resin, an acrylate,
a polyimide for example) or a hybrid matrix (organic-inorganic) to produce a coatable Nanomer composite system. he modular principle makes it possible to achieve a number of properties at one
Surface-modified nanoparticles endow coatings with combined propertie e
#Nano-spirals could guard against identity theft (Nanowerk News) Take gold spirals about the size of a dimeand shrink them down about six million times.
Most other investigators who have studied the remarkable properties of microscopic spirals have done so by arranging discrete nanoparticles in a spiral pattern:
Although some successful examples of the incorporation of these complexes into micro/nanoparticles and liquids crystals have been reported during the last years,
#Next-generation illumination using silicon quantum dot-based white-blue LED (Nanowerk News) A silicon quantum dot (QD)- based hybrid inorganic/organic light-emitting diode (LED) that exhibits white-blue electroluminescence
and their collaborators (Applied Physics Letters,"White-blue electroluminescence from a Si quantum dot hybrid light-emitting diode").
The discoveries published in the journal ACS Nano("Bio-Inspired Structural Colors Produced via Self-Assembly of Synthetic Melanin Nanoparticles")reflect a milestone in biomimicry research.
simple process for making platinum"nano-raspberries"microscopic clusters of nanoscale particles of the precious metal("Stability and phase transfer of catalytically active platinum nanoparticle suspensions").
"Colorized micrographs of platinum nanoparticles made at NIST. The raspberry color suggests the particles? corrugated shape,
Nanoparticles can act as catalysts to help convert methanol to electricity in fuel cells. NIST's 40-minute process for making nano-raspberries, described in a new paper,*has several advantages.
For fuel cells, nanoparticles often are mixed with solvents to bind them to an electrode. To learn how such formulas affect particle properties,
Because the nanoparticles clumped up slowly and not too much in methanol, the researchers concluded that the particles could be transferred to that solvent,
It is made from gelatin-based biomaterials reinforced with nanoparticles and seeded with cells, and it mimics the anatomical microenvironment of lymphoid tissue.
The engineers reinforced the material with silicate nanoparticles to keep the structure from melting at the physiologically relevant temperature of 98.6 degrees.
"Perhaps the first target for applying this new HRSEM surface analytic technique will be the study of surface structures on the facets of nanoparticles.
The surface structures of nanoparticle facets are extremely challenging to image in the plan view (seen from above) using electron microscopy,
since scanning probe techniques cannot usually address nanoparticle surfaces at atomic resolution, and surface X-ray diffraction requires large, single crystal surfaces."
The device, described in a study published June 23 in Nature Communications("Bifunctional non-noble metal oxide nanoparticle electrocatalysts through lithium-induced conversion for overall water splitting"),could provide a renewable source of clean
Once the researchers designed these ntelligent insulin nanoparticles, they had to figure out a way to administer them to patients with diabetes.
Gu created these icroneedlesusing the same hyaluronic acid that was a chief ingredient of the nanoparticles,
#Biomanufacturing of Cds quantum dots A team of Lehigh University engineers have demonstrated a bacterial method for the low-cost, environmentally friendly synthesis of aqueous soluble quantum dot (QD) nanocrystals at room temperature.
scalable and green synthesis of Cds nanocrystals with extrinsic crystallite size control in the quantum confinement range.
The result is Cds semiconductor nanocrystals with associated size-dependent band gap and photoluminescent properties. This biosynthetic approach provides a viable pathway to realize the promise of green biomanufacturing of these materials.
#Nanoparticle'wrapper'delivers chemical that stops fatty buildup in rodent arteries In what may be a major leap forward in the quest for new treatments of the most common form of cardiovascular disease,
and reverse the progression of atherosclerosis in rodents by loading microscopic nanoparticles with a chemical that restores the animals'ability to properly handle cholesterol.
and track the nanoparticles'movement inside the animals'bodies by tagging them with a radioactive tracer that lit up on a CT SCAN.
Because the nanoparticles carrying D-PDMP are made of a common laxative ingredient and a naturally occurring sebacic acid,
The possibility to study the optical properties of individual nanoparticles or macromolecules promises intriguing potential for many areas of biology, chemistry,
"Intuitive illustration of the new method for imaging nanoparticles. Graphic: MPQ, Laser spectroscopy Division) Spectroscopic measurements on large ensembles of nanoparticles suffer from the fact that individual differences in size, shape,
and molecular composition are washed out and only average quantities can be extracted. There is thus a large interest to develop single-particle-sensitive techniques.
one side of the resonator is made of a plane mirror that serves at the same time as a carrier for the nanoparticles under investigation.
which was reported recently in the Journal of Nanoparticle Research("Minimal geometric requirements for micropropulsion via magnetic rotation),
#Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells (Nanowerk News) Nanoparticles packed with a clinically used chemotherapy drug
This laboratory and animal study showed that nanoparticles coated with the oligosaccharide called chitosan and encapsulating the chemotherapy drug doxorubicin can target
The study is reported in the journal ACS Nano("Chitosan-Decorated Doxorubicin-Encapsulated Nanoparticle Targets and Eliminates Tumor Reinitiating Cancer Stem-like Cells").
""Our findings indicate that this nanoparticle delivery system increases the cytotoxicity of doxorubicin with no evidence of systemic toxic side effects in our animal model,
"We believe that chitosan-decorated nanoparticles could also encapsulate other types of chemotherapy and be used to treat many types of cancer."
enabling the nanoparticles to target the malignant stem-like cells in a tumor. The nanoparticles were engineered to shrink,
break open, and release the anticancer drug under the acidic conditions of the tumor microenvironment and in tumor-cell endosomes and lysosomes,
although the drug-carrying nanoparticles could bind to the variant CD44 receptors on cancerous mammosphere cells,
Nanoparticles would then make it possible to measure with nanometre accuracy, i e. on the scale of viruses. The maximum length of the sensor fibre is currently around 400 metres,
The first results achieved using"scanning quantum dot microscopy"have been published in the current issue of Physical Review Letters("Scanning Quantum dot Microscopy".
A single silver atom on a silver substrate (Ag (111)) under the scanning quantum dot microscope.
the scientists in Jlich attached a single molecule as a quantum dot to the tip of the microscope.
The scanning quantum dot micrograph of a PTCDA molecule reveals the negative partial charges at the ends of the molecule as well as the positive partial charges in the centre.
"In contrast to many other forms of scanning probe microscopy, scanning quantum dot microscopy can even work at a distance of several nanometres.
one example would be made quantum dots of nanocrystals like those already being used in fundamental research h
Guo focuses much of his work on the use of ribonucleic acid (RNA) nanoparticles and a viral nanomotor to fight cancer
He is well-known for his pioneering work of constructing RNA nanoparticles as drug carriers u
Taking advantage of cottons irregular topography, Hinestroza and his students added conformal coatings of gold nanoparticles,
Synthesizing nanoparticles and attaching them to cotton not only creates color on fiber surfaces without the use of dyes,
#The influence of surface structure on nanoparticle shape control (Nanowerk News) Peng Zhang, a professor with Dalhousies Department of chemistry,
Published this week in Nature Communications("The surface structure of silver-coated gold nanocrystals and its influence on shape control"),Zhangs teams report on the discovery of a new methodology to study nanoparticle structures.
Dr. Zhang and his Phd student Daniel Padmos examined gold and silver nanoparticles two very important materials, particularly in the future of biomedicine.
On the other hand, nanosilver could have potential applications in fighting bacterial diseases. Uncovering shape The shape of the surface of nanoparticles is key,
because different shapes lead to different properties and different properties lead to different behaviours. To better understand the potential applications of nanogold and nanosilver in the long run
scientists must first know much more about their surface structure. But, matter on the nanoscale is challenging to observe.
These nanoparticles are very difficult to study, explains Dr. Zhang, pointing out that ordinary techniques like electron microscopes dont provide the amount of detail necessary to understand whats happening on the surface of nanomaterials.
the team was able to comprehensively study the surface of a nanoparticle. In their nanomaterial system composed primarily of gold, silver and chloride,
and nanosilver, keeping them stable. Its a little like cooking, explains Dr. Zhang. You throw in a bunch of ingredients,
but we didnt know how it stays on the surface of nanogold and nanosilver. Our team found out how, at the atomic level.
#Environmentally friendly lignin nanoparticle'greens'silver nanobullet to battle bacteria North carolina State university researchers have developed an effective
In a study published in Nature Nanotechnology("An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core),
"NC State engineer Orlin Velev and colleagues show that silver-ion infused lignin nanoparticles, which are coated with a charged polymer layer that helps them adhere to the target microbes,
As the nanoparticles wipe out the targeted bacteria, they become depleted of silver. The remaining particles degrade easily after disposal because of their biocompatible lignin core,
People have been interested in using silver nanoparticles for antimicrobial purposes, but there are lingering concerns about their environmental impact due to the long-term effects of the used metal nanoparticles released in the environment,
said Velev, INVISTA Professor of Chemical and Biomolecular engineering at NC State and the papers corresponding author.
The researchers used the nanoparticles to attack E coli a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium;
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
Alexander Richter, the papers first author and an NC State Ph d. candidate who won a 2015 Lemelson-MIT prize,
that uses gold nanoparticles and paper has been devised by researchers from the A*STAR Institute of Bioengineering and Nanotechnology("Trapping cells in paper for white blood cell count").
The technique employs gold nanoparticles coated with an antibody that interacts with white blood cells. The antibody causes the nanoparticles to attach themselves to white blood cells in a blood sample,
which can be obtained by simply pricking a finger. The blood sample is filtered passively through a small test paper.
A dark spot then forms on the paper surface due to the gold nanoparticles on the white blood cells.
such as sickle-cell detection and platelet count, explains Ying. e are also planning to measure different types of white blood cells by introducing gold nanoparticles coated with different antibodies. a
Sticky-flares are tiny spherical nucleic acid gold nanoparticle conjugates that can enter living cells and target and transfer a fluorescent reporter or"tracking device"to RNA transcripts.
#Degrading BPA with visible light and a new hybrid nanoparticle photocatalyst Over the course of the last half century, BPA has gone from miracle to menace.
When light strikes a photocatalyst like titanium dioxide (Tio2) nanoparticles the jolt of energy can kick one of its electrons up to an excited state
In order to turn Tio2 nanoparticles into a better photocatalyst, the researchers made several modifications. First, they added silver to the surface of the nanoparticles,
a common technique to enhance the charge separation. When light strikes Tio2 and excites one of its electrons
Then, they wrapped the Ag/Tio2 nanoparticles in sheets of reduced graphene oxide (RGO), a thin layer of carbon atoms arranged in a honeycomb pattern.
It also reduced the nanoparticles'bandgap, decreasing the amount of energy necessary to activate the photocatalyst.
When the researchers mixed the hybrid nanoparticles with BPA solution under an artificial visible light source
Furthermore, the RGO-Ag-Tio2 nanoparticles outperformed those where RGO or Ag alone were added to the Tio2,
#New study shows how nanoparticles can clean up environmental pollutants Many human-made pollutants in the environment resist degradation through natural processes,
In a new paper published this week in Nature Communications("Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil),
"researchers from MIT and the Federal University of Goiás in Brazil demonstrate a novel method for using nanoparticles
Nanoparticles that lose their stability upon irradiation with light have been designed to extract endocrine disruptors, pesticides,
The system exploits the large surface-to-volume ratio of nanoparticles, while the photoinduced precipitation ensures nanomaterials are released not in the environment.
They initially sought to develop nanoparticles that could be used to deliver drugs to cancer cells. Brandl had synthesized previously polymers that could be cleaved apart by exposure to UV LIGHT.
Nanoparticles made from these polymers have a hydrophobic core and a hydrophilic shell. Due to molecular-scale forces
in a solution hydrophobic pollutant molecules move toward the hydrophobic nanoparticles, and adsorb onto their surface,
The fundamental breakthrough, according to the researchers, was confirming that small molecules do indeed adsorb passively onto the surface of nanoparticles. o the best of our knowledge,
it is the first time that the interactions of small molecules with preformed nanoparticles can be measured directly,
we showed in a system that the adsorption of small molecules on the surface of the nanoparticles can be used for extraction of any kind,
"The group is now working to use the plasmonic structure to create a single photon source--a necessity for extremely secure quantum communications--by sandwiching a single quantum dot in the gap between the silver nanocube and gold foil.
and can aggregate into nanoparticles or micelles. Versatile nanostructures made from CO2 based polycarbonates. Wiley-VCH) CO2 and epoxides (highly reactive compounds with a three-membered ring made of two carbon atoms
"We show how these crystals can be built up into complex structures by attaching particles as nanocrystals, clusters,
They can be small molecules, clusters, droplets, or nanocrystals. All of these particles are unstable and begin to combine with each other and with nearby crystals and other surfaces.
For example, nanocrystals prefer to become oriented along the same direction as the larger crystal before attaching,
The computer working involves using droplets of water soaked with magnetic nanoparticles, the computer then uses electromagnetic field to pump the droplets around gates to perform logical operations.
New Digital Conference Explores Biophotonics Imaging Fluorescent, Magnetic nanoparticles Aid Bioimaging System Combines Optical Microscopy, MRI Bioimaging Technique Isolates Moving Tissu i
and diamond nanoparticles are also incredibly slippery, which can be useful if you want to reduce friction in a moving machine.
When the diamond nanoparticles came in contact with the thin sheets of graphene (carbon that's only an atom thick) the graphene rolled up around the diamond nanoparticles,
#Gold Nano-Spirals Could Protect Against Identity Theft Most other investigators who have studied the remarkable properties of microscopic spirals have done so by arranging discrete nanoparticles in a spiral pattern:
The next steps for Méndez and her team will be modifying the commercial screen-printed electrodes with nanoparticles to make the sensors respond more clearly,
but although it was easy enough to work out how to control water droplets-by infusing them with magnetic nanoparticles
#Here's how to make carbon nanoparticles with honey and a microwave Carbon nanoparticles can be incredibly useful in the treatment of many types of disease,
as they can evade our natural immune defences and deliver medicine to wherever it's most needed in the body.
but so far creating these nanoparticles has been a long and expensive process. Now researchers at the University of Illinois in the US have found a much easier way to create a certain type of nanoparticle:
using a process that involves plain old honey and a microwave. The resulting particles are less than 8 nanometres thick (a human hair is around 80,000-100,000 nanometres)
but that is nanoparticles with high luminescence. This is one of the simplest systems that we can think of.
the microwave-produced nanoparticles are effective in delivering the drugs where they're needed, and vibrational spectroscopic techniques were used to monitor how the polymers gradually released their payload.
Different polymer coatings were tested too as the team works towards getting these'homemade'carbon nanoparticles ready for clinical use."
Nanowire and contact formed at the same time Nanowires are extremely thin nanocrystal threads used in the development of new electronic components
Walther and colleagues compared nanoplatelets of different size.""The nacre-mimetics based on small clays are very tough.
and nanoparticles that can be targeted to specific tumors. Recently, Mohs was awarded a $1. 37 million research grant from the National Institute of Biomedical Imaging
Under the four-year project, Mohsteam will develop nanoparticles based on hyaluronic acid, a substance naturally present in the human body.
These nanoparticles will have the ability to entrap near infrared fluorescent dyes. The research will investigate invasive ductal carcinoma, the most common type of breast cancer.
reduced the amount of nanoparticles that were being cleared by the liver and spleen by about 50 percent.
As a result, the nanoparticles remained in the blood stream for longer periods of time.
One hour later, they administered a dose of a platinum-based chemotherapy drug that had been incorporated into a nanoparticle.
Then they carefully injected into the mix individual water droplets that had been infused with tiny magnetic nanoparticles.
It is made from gelatin-based biomaterials reinforced with nanoparticles and seeded with cells, and it mimics the anatomical microenvironment of lymphoid tissue.
The engineers reinforced the material with silicate nanoparticles to keep the structure from melting at the physiologically relevant temperature of 98.6 degrees.
"It appears that they form uranium nanoparticles, "he said, but the mineralogy is still not well known
#Biomanufacturing of Cds quantum dots A team of Lehigh University engineers have demonstrated a bacterial method for the low-cost, environmentally friendly synthesis of aqueous soluble quantum dot (QD) nanocrystals at room temperature.
scalable and green synthesis of Cds nanocrystals with extrinsic crystallite size control in the quantum confinement range.
The result is Cds semiconductor nanocrystals with associated size-dependent band gap and photoluminescent properties. This biosynthetic approach provides a viable pathway to realize the promise of green biomanufacturing of these materials.
#Novel microscope for nanosystems LMU/MPQ-scientists can image the optical properties of individual nanoparticles with a novel microscope.
The possibility to study the optical properties of individual nanoparticles or macromolecules promises intriguing potential for many areas of biology, chemistry, and nanoscience.
Spectroscopic measurements on large ensembles of nanoparticles suffer from the fact that individual differences in size, shape,
one side of the resonator is made of a plane mirror that serves at the same time as a carrier for the nanoparticles under investigation.
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