such as platinum-copper single atom alloy nanoparticles supported on an alumina substrate, and then tested them under industrial pressure and temperatures."
In addition, the product is able to form hydroxyapatite nanoparticles to create chemical bonds with bone tissue in the body.
Titanium dioxide nanoparticles doped with elements such as strontium and chrome were used in the production of the coating.
The coating of nanoparticles contains titanium dioxide and other spherical nanoparticles in average size of 60 nm.
they found out that silicon nanoparticles are exhibit strong resonances in the visible spectrum-the so-called magnetic dipole resonances.
This type of resonance is characterized by strong localization of light waves on subwavelength scales, inside the nanoparticles.
Nanoparticles were fabricated in the Australian National University by e-beam lithography followed by plasma-phase etching.
In the nearest future, we are going to test such nanoparticles in integrated circuits
#Magnetic Nanosorbents Eliminate Fluoride from Water Researchers from Tehran University of Medical sciences used low-cost and available raw materials for the laboratorial production of nanosorbents with high efficiency in elimination of fluoride from contaminated water.
The spherical arrangement of approximately 100 DNA strands attached to a benign nanoparticle core made of lipid
The single stranded-dna DNA on the nanoparticle core can be positioned ideally and oriented to specifically and fully interact with the targeted toll-like receptors.
The study is published today in the journal Physical Review Letters("Cavity cooling a single charged nanoparticle".
Observing quantum effects in large and heavy objects like these nanoparticles would also shed light on the role of gravity in quantum physics s
The ultrathin nanoparticles are embedded in a collagen-based hydrogel a biodegradable gel used in several biomedical applications because of its compatibility with the body.
would allow the injury site to receive blood flow as part of the enhanced healing process initiated by the nanoparticles.
#Medical nanoparticles for the local treatment of lung cancer Nanoparticles can function as carriers for medicines to combat lung cancer:
In the journal, ACS Nano("Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors"),the scientists reported that this approach led to a significant increase
Sabine van Rijt, CPC/ilbd, Helmholtz Zentrum Mnchen) Nanoparticles are extremely small particles that can be modified for a variety of uses in the medical field.
For example, nanoparticles can be engineered to be able to transport medicines specifically to the disease site while not interfering with healthy body parts.
were able to show nanoparticles'selective drug release to human lung tumour tissue for the first time. Tumour specific proteins were used to release drugs from the nanocarriers Tumour tissue in the lung contains high concentrations of certain proteases,
#Novel nanoparticle therapy promotes wound healing (w/video)( Nanowerk News) An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal
"e envision that our nanoparticle therapy could be used to speed the healing of all sorts of wounds,
and then put the drug in tiny gel capsules called nanoparticles and applied the nanoparticles to wounds on mice.
The treated wounds healed much faster than untreated wounds. FL2 belongs to the fidgetin family of enzymes,
and study co-leader Adam Friedman, M d.,director of dermatologic research at Einstein and Montefiore, who together had developed nanoparticles that protect molecules such as sirna from being degraded as they ferry the molecules to their intended targets.
The nanoparticles with their sirna cargoes were tested then by topically applying them to mice with either skin excisions or burns.
#Nanoparticles provide novel way to apply drugs to dental plaque Therapeutic agents intended to reduce dental plaque
Their findings have been published in the journal ACS Nano("ph-Activated Nanoparticles for Controlled Topical Delivery of Farnesol To Disrupt Oral Biofilm Virulence".
"Farnesol is released from the nanoparticle carriers into the cavity-causing dental plaque. Graphic by Michael Osadciw/University of Rochester.
referred to as a nanoparticle carrier. They constructed the outer layer out of cationicor positively chargedsegments of the polymers.
the same is true of the nanoparticles and HA. Because teeth are coated with saliva, the researchers werent certain the nanoparticles would adhere.
But not only did the particles stay in place, they were also able to bind with the polymeric matrix
Since the nanoparticles could bind both to saliva-coated teeth and within plaque, Benoit and colleagues used them to carry an antibacterial agent to the targeted sites.
In other words, the nanoparticles release the drug when exposed to cavity-causing eating habitsprecisely when it is needed most to quickly stop acid-producing bacteria.
When the drug was administered without the nanoparticle carriers, there was no effect on the number of cavities and only a very small reduction in their severity.
But when it was delivered by the nanoparticle carriers, both the number and severity of the cavities were reduced.
Their soft nanoparticles stick to the plane where oil and water meet, but do not stick to one another.
effectively acting as a 2-D liquid("Interactions and Stress Relaxation in Monolayers of Soft Nanoparticles at Fluid-Fluid Interfaces".
"The researchers created a 2-D liquid consisting of nanoparticles at the interface between a drop of oil and the surrounding water.
The researchers created a 2-D liquid consisting of nanoparticles at the interface between a drop of oil and the surrounding water.
crystalline Ptni3 nanoparticles, are transformed in solution and at mild temperatures into Pt3ni nanoframes with surfaces that have three-dimensional molecular accessibility.
The Pt-rich edges of the starting Ptni3 nanoparticles are maintained in the final Pt3ni nanoframes.
Published in NANO Letters("Real-time Visualization of Nanoparticles Interacting with Glioblastoma Stem Cells), "the study was led by Zhi Sheng and Deborah Kelly, both assistant professors at the institute,
#Lanthanide-organic framework nanothermometers prepared by spray-drying A work in Advanced Functional Materials shows how spray-drying prepared MOF nanoparticles containing lanthanide metals may be used as nanothermometers operative over a wide range of temperatures
The article also shows that spray-drying prepared MOF nanoparticles may be used as ratiometric luminescent nanothermometers operative over a wide range of temperatures, in particular, in the cryogenic range.
Prof Maspoch and Dr Imaz have contributed in the synthesis of the MOF nanoparticles of Tb (III) and Eu (III),
They sprayed a fine dusting of silica nanoparticles onto the stainless steel mesh to create a randomly bumpy surface
"He explained that certain combinations of layers yield nanoparticles that bind to oil instead of repelling it.
#Nanoparticles could make big impact for patients in need of cornea transplant There are about 48,000 corneal transplants done each year in the U s,
Johns Hopkins Medicine researchers may have discovered a way to prevent rejection by using biodegradable nanoparticles that release needed medication into the eye after surgery.
In an animal study being published in the March 10 issue of the Journal of Controlled Release("Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats),
biodegradable nanoparticle loaded with corticosteroids for timed release of medicine. The other three groups received weekly injections of saline, placebo nanoparticles and free dexamethasone sodium phosphate aqueous solution after surgery, respectively.
Treatments were given until the graft was deemed clinically as failed or until the nine-week test period concluded.
For rats that received the nanoparticle loaded with corticosteroids, 65 percent of the treatment remained in the eye
Two weeks after surgery, rats that received the placebo nanoparticle and saline injections had severe swelling, opaque corneas and unwanted growth of new blood vessels, all indicating graft failure.
The only group that showed successful corneal transplant was the group of rats that received the corticosteroid-loaded nanoparticle injections.
while making medicine adherence much easier on patients and their families The nanoparticle loaded with medication could eliminate the need for a patient to remember to take their medicine often multiple doses per hour after a surgery,
Scientists curve nanoparticle sheets into complex forms (Nanowerk News) Scientists have been making nanoparticles for more than two decades in two-dimensional sheets, three-dimensional crystals and random clusters.
But they have never been able to get a sheet of nanoparticles to curve or fold into a complex three-dimensional structure.
But its a very thin membrane made of a single layer of nanoparticles. To their surprise,
so they end up distributing themselves in a nonuniform way across the top and bottom layers of the nanoparticle sheet.
to analyze the surface of the nanoparticles. They discovered that the amount of surface covered by the organic molecules
In principle, scientists could use this method to induce folding in any nanoparticle membrane that has an asymmetrical distribution of surface molecules.
The results were published online in Nature Communications on August 4, 2015("A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models".
forming a water-soluble nanoparticle with the drug hidden in its core. These nanoparticles are highly soluble in blood
and are the perfect size to penetrate and accumulate in tumors where they take advantage of a tumor's acidic environment."
These microcapsules, in turn, are packed with nanoparticles that can be filled with drugs. Heres how it works:
The drugs leak slowly out of the nanoparticles and are stored in the microcapsules. When the elastic film is stretched,
the microcapsule is recharged by the drugs that continue to leak out of the nanoparticles. This can be used to apply drugs directly to sites on the skin,
colloidal nanoparticles may play a role in digital technologies of the future. Nanoparticles can be displaced rapidly,
require little energy and their small footprint offers large storage capacity all these attributes make them well suited to new data storage applications or high-resolution displays.
These nanoparticles are constantly in motion due to the principle of Brownian motion. Since the particles are charged electrically,
In a new study, she and her colleagues have demonstrated now that it is not only possible to spatially confine nanoparticles,
"Nanoparticles possess properties that are very useful for digital technologies, and each individual particle can now be used to store
The targeted manipulation of individual nanoparticles opens up new options for their application, including in future data storage media
We replaced the molecular dyes in previous LSC systems with core/shell nanoparticles composed of cadmium selenide (Cdse) cores
The Cdse/Cds nanoparticles enabled us to decouple absorption from emission energy and volume, which in turn allowed us to balance absorption
and scattering to obtain the optimum nanoparticle, he says. Our use of photonic mirrors that are matched carefully to the narrow bandwidth of our quantum dot lumophores allowed us to achieve waveguide efficiency exceeding the limit imposed by total internal reflection.
The success of this Cdse/Cds nanoparticle-based LSC system led to a partnership between Berkeley Lab, the University of Illinois, Caltech and the National Renewable energy Lab (NREL) on a new solar
and have been published in the leading British journal Nature Nanotechnology("Evolution of a Designless Nanoparticle Network into Reconfigurable Boolean logic").
#Nanoparticles could boost effectiveness and reduce side effects of allergy shots Whether triggered by cats, bees, pollen or mites,
researchers have developed nanoparticles that envelop an allergen and deliver it to specific cells. But these carriers degrade too slowly,
made with bioadhesive nanoparticles, that stays on the surface of the skin. Results of the research appear in the Sept. 28 online edition of the journal Nature Materials. e found that
and our nanoparticles are so adhesive that they don even go into hair follicles, which are relatively open.
UV exposed skin vs nanoparticle-treated, UV exposed skin. The merged images from rows two and three of this figure show two images of skin cells showing DNA damage in the form of double-strand breaks in sunscreen-treated, UV
exposed skin vs nanoparticle-treated, UV exposed skin. Girardi, who specializes in skin cancer development and progression, said little research has been done on the ultimate effects of sunblock usage and the generation of ROS, ut obviously,
the researchers developed a nanoparticle with a surface coating rich in aldehyde groups, which stick tenaciously to the outer skin layer.
The nanoparticle hydrophilic layer essentially locks in the active ingredient, a hydrophobic chemical called padimate O. Some sunscreen solutions that use larger particles of inorganic compounds, such as titanium dioxide or zinc oxide,
By using a nanoparticle to encase padimate O an organic chemical used in many commercial sunscreens,
Previously, nanoparticle walkers were only able to walk on precise and programmed one-and two-dimensional paths.
"This work demonstrates the unique capability of micro-to-nanoscale topographies of the crumpled graphene-Au nanoparticles--higher density,
bringing the nanoparticles closer, "explained Juyoung Leem, a graduate student and first author of the study published in Nano Letters("Mechanically Self-Assembled, Three-dimensional Grapheneold Hybrid Nanostructures for Advanced Nanoplasmonic Sensors").
This process enables precise control and optimization of the size and spacing of integrated Au nanoparticles on crumpled graphene for higher SERS enhancement."
"According to Nam, the 3d crumpled graphene-Au nanostructure exhibits at least one order of magnitude higher SERS detection sensitivity than that of conventional, flat graphene-Au nanoparticles.
either using more nanoparticles or more electrodes. he electrodes are probably more important, so that you can have more inputs and outputs. o
"and"nanoparticle"are probably not terms you find yourself using in day-to-day interactions, but for the Univ. of Cincinnati (UC)' s Yoonjee Park, assistant professor in the College of Engineering and Applied science biomedical engineering professor, these words are central to every conversation relating to her cutting edge research on drug delivery vehicles.
"Usually I use nanoparticles for drug delivery vehicles, and we can attach image and contrast agents to the nanoparticle to track the particle.
Or the nanoparticle itself is the image and contrast agent which makes a complex of the image and contrast agent with the drug itself."
"In the course of time Park began to focus her efforts on those parts of the body that posed a significant challenge
Her Phd at Purdue University and her research at Boston's Massachusetts institute of technology were dedicated both to studying particle stabilization to avoid clogging arteries with the nanoparticles and drug delivery vehicles;
the scientists had to add platinum nanoparticles and an electron donor to their powder polymer."
"The platinum nanoparticles work as microelectrodes on which the electrons are transferred from the COF to the protons to form hydrogen,
he said. here are so many atoms inside the nanoparticle that never do anything. But in our process the atoms driving catalysis have no metal atoms next to them.
They then filled this mould with a suspension containing aluminium oxide platelets and glass nanoparticles as mortar.
Huo and her team at UCF's Nanoscience Technology Center developed a technique known as nanoparticle-enabled dynamic light scattering assay (Nanodlsay) to measure the size of the particles by analyzing the light they throw off.
A small bottle of nanoparticles suspended in water costs about $250, and contains enough for about 2, 500 tests."
#Researchers deliver large particles into cells at high speed The researchers created a highly efficient automated tool that delivers nanoparticles, enzymes, antibodies, bacteria and other"large-sized"cargo into mammalian cells at the rate
#Efficient method of producing metallic nanoparticles VTT's aerosol technology reactor for nanoparticle production can generate a variety of pure metal particles, particles of various alloys and carbon-coated particles.
The reactor can efficiently produce hundreds of grammes or even kilogrammes of nanoparticles per day."
"Demand has outstripped supply in the nanoparticle markets. This has been an obstacle to the development of product applications;
Nanoparticles have also been tested in the manufacture of magnetic inks and inks that conduct electricity in printed electronics.
The silicon nanoparticles it produces may even enable lithium battery capacity to be boosted by a factor of 10.
where the light is concentrated around each nanoparticle and then amplified. In contrast to conventional laser cavities, no mirrors are required for the light to bounce back and forth.
the nanoparticle cavity stays fixed and does not change; only the liquid gain around the nanoparticles changes.
The main advantages of very small lasers are: Some technical backgroundplasmon lasers are promising nanoscale coherent sources of optical fields
Knowing the nanoparticle's most stable configurations, Zeng said, could allow biomedical engineers to identify appropriate binding sites for drugs used to treat cancer and other diseases.
The group developed a sensitive biosensing platform that detects E coli by the aggregation of nanoparticles on cellulose Paper gold nanoparticles are covered with surface molecules that bind to E coli bacteria.
When the test fluid containing bacteria is mixed with the nanoparticles and transferred to the cellulose paper, the aggregation results in a blue spot.
creating an electrode made of nanoparticles with a solid shell, and a"yolk"inside that can change size again and again without affecting the shell.
The use of nanoparticles with an aluminum yolk and a titanium dioxide shell has proven to be"the high-rate champion among high-capacity anodes"
That's where the idea of using confined aluminum in the form of a yolk-shell nanoparticle came in.
what are called"core-shell"and"yolk-shell"nanoparticles. The former have a shell that is bonded directly to the core,
Wave-particle dualism with large molecules The virtual laboratories provide an insight into the fundamental understanding and into the applications of quantum mechanics with macromolecules and nanoparticles.
research shows Researchers at the University of Birmingham have shown how the development of coated silica nanoparticles could be used in restorative treatment of sensitive teeth
and Zhitomirsky, a materials science and engineering professor, demonstrates an improved three-dimensional energy storage device constructed by trapping functional nanoparticles within the walls of a nanocellulose foam.
semiconducting and insulating nanoparticles. Currently, printed conductive patterns use a combination of poorly conducting carbon with other materials, most commonly silver
shows considerable protection against malaria when displayed on Archaeal gas vesicle nanoparticles. A vaccine based on this motif could confer protection against all malaria parasites.
when displayed on novel nanoparticles. This approach has the potential to prevent the parasite from multiplying in the human host
Shiladitya Dassarma's laboratory at the University of Maryland School of medicine, Baltimore, USA, who has developed Archaeal gas vesicle nanoparticles (GVNPS.
The small unique segment of enolase was fused genetically to a nanoparticle protein and this conjugated system was used to vaccinate mice.
#Engineers design magnetic cell sensors MIT engineers have designed magnetic protein nanoparticles that can be used to track cells
"Ferritin, which is as close as biology has given us to a naturally magnetic protein nanoparticle,
"The new"hypermagnetic"protein nanoparticles can be produced within cells, allowing the cells to be imaged or sorted using magnetic techniques.
"Rather than actually making a nanoparticle in the lab and attaching it to cells or injecting it into cells,
Following a postdoctoral stint at the University of Virginia (UVA), she was also able to dope the paper with relatively inexpensive copper nanoparticles. he paper is really thick and sturdy,
#Nanoparticles used to breach mucus barrier in lungs Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases Nanotechnology could one day provide an inhaled vehicle to deliver targeted therapeutic genes
and Federal University of Rio de janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue proving the concept,
or replacement genes or drugs inside a man-made biodegradable nanoparticle rapperthat patients inhale could penetrate the mucus barrier
Suk says their work with nanoparticles grew out of failed efforts to deliver treatments to people with lung diseases.
but it also makes the airway mucus harder to overcome by inhaled therapeutic nanoparticles. Most of the existing drugs for CF help clear infections but do not solve the disease underlying problems.
or corrective genes via the mucus-penetrating DNA-loaded nanoparticles could mediate production of normal, unctionalproteins long term.
DNA-loaded nanoparticles possess positive charge that caused them to adhere to negatively charged biological environments, in this case the mucus covering the lung airways.
In other words, conventional nanoparticles are too sticky to avoid unwanted off-target interactions during their journey toward the target cells.
the team developed a simple method to densely coat the nanoparticles with a nonsticky polymer called PEG,
They showed that these nanoparticles retained their sizes at a physiological environment and are capable of rapidly penetrating human airway mucus freshly collected from patients visiting the Johns Hopkins Adult Cystic fibrosis Program directed by Michael Boyle,
They demonstrated that inhaled delivery of the genes via the mucus-penetrating nanoparticles resulted in widespread production of the protein to levels superior to gold-standard,
adding that the nanoparticles did not appear to show any adverse effects, such as increased lung inflammation.
Scientists curve nanoparticle sheets into complex forms Scientists have been making nanoparticles for more than two decades in two-dimensional sheets, three-dimensional crystals and random clusters.
But they have never been able to get a sheet of nanoparticles to curve or fold into a complex three-dimensional structure.
the staff scientist at the Center for Nanoscale Materials who led the project. ut it a very thin membrane made of a single layer of nanoparticles. rgonne researchers are able to fold gold nanoparticle membranes in a specific
so they end up distributing themselves in a nonuniform way across the top and bottom layers of the nanoparticle sheet.
to analyze the surface of the nanoparticles. They discovered that the amount of surface covered by the organic molecules
scientists could use this method to induce folding in any nanoparticle membrane that has an asymmetrical distribution of surface molecules.
SEM images (false colour) depicting the intricate gel fibre architecture They then discovered that intertwined amongst these microscopic fibres were a profusion of nanoparticles around 100 nanometres in size.
An X-ray diffraction technique confirmed that these were nanoparticles of KUST-1 a copper-based Metal-Organic Framework (MOF) notable for its very large surface area (exceeding 2000 square-metres in each gram.
his fascinating phenomenon is exceptionally rare for gel systems incorporating MOF nanoparticles; to the best of our knowledge this is the first example of its kind reported in the literature.
But it the promise of MOF nanoparticles suitable to make into thin films for sensors and microelectronics that is particularly alluring.
e discovered that copious amounts of high-quality HKUST-1 (MOF) nanoparticles can be harvested straightforwardly by breaking down the gel fibres using methanol. hese MOF nanoparticles can then be used as a recursor making it easy to fabricate multifunctional thin
Thin film sensors created using MOF nanoparticles harvested from hybrid gels The team worked with Isis Innovation to patent the technology and Samsung Electronics
semiconducting and insulating nanoparticles. Currently, printed conductive patterns use a combination of poorly conducting carbon with other materials, most commonly silver,
and engineering, allowing researchers to open new windows into phenomena as vast as the universe and as small as nanoparticles.
#Nanotechnology could spur new heart treatment for arrthymia A new nanoparticle developed by University of Michigan researchers could be the key to a targeted therapy for cardiac arrhythmia,
The major challenge of adapting the therapy to heart cells was developing a nanoparticle small enough to penetrate the tiny pores inside heart capillaries,
we used nanoparticles that were about 120 nanometers in size, says Kopelman. o work inside the heart,
The team tested a treatment that delivers the photo sensitizing chemical (made from algae) to the targeted cells by injecting nanoparticles loaded with both the chemical
and an amino acid-based peptide that causes the nanoparticles to be taken up only by the targeted cells.
The low-level light destroys only the cells that have absorbed the nanoparticles leaving the other heart cells unharmed.
The team is also working to devise a method for producing larger quantities of the nanoparticles at pharmaceutical-grade standards.
Previously, nanoparticle walkers were only able to walk on precise and programmed one-and two-dimensional paths.
These microcapsules, in turn, are packed with nanoparticles that can be filled with drugs. The university said in a statement that the microcapsules stick halfway out of the film, on the side of the film that touches a patient skin.
The drugs release slowly from the nanoparticles and are stored in the microcapsules. When the elastic film is stretched
After being stretched, the microcapsule is refilled by the drugs that continue to leak out of the nanoparticles. his can be used to apply drugs directly to sites on the skin
#Optimal particle size for anticancer nanomedicines discovered Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues
There has been a major push recently in the field to miniaturize nanoparticle size using novel chemistry
and retention the researchers developed a mathematical model of the spatiotemporal distribution of nanoparticles within a spherically symmetric tumor.
and Chinese researchers show how a unique nano-alloy composed of palladium nano-islands embedded in tungsten nanoparticles creates a new type of catalysts for highly efficient oxygen reduction the most important reaction in hydrogen fuel cells.
To stabilize the nanoparticles in practical applications they are anchored on ordered mesoporous carbon. The anchoring keep the nanoparticles stable over long time by hindering them from fusing together in the fuel cell tests.
The unique formation of the material is based on a synthesis method which can be performed in an ordinary kitchen microwave oven purchased at the local supermarket.
#Nanoparticles can act like liquid on the outside, crystal on the inside A surprising phenomenon has been found in metal nanoparticles:
or 1763 degrees Fahrenheit--so observation of any liquidlike behavior in its nanoparticles was unexpected quite Li says.
The use of nanoparticles in applications ranging from electronics to pharmaceuticals is a lively area of research;
If the nanoparticles are protected by even a vanishingly thin layer of oxide the liquidlike behavior is eliminated almost completely making stable circuits possible.
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