| Catalytic activity (25) |  |
| Chemotherapy drug (40) | |
| Macromolecule (10) | |
| Monolayer (79) | |
| Catalytic activity (25) | |
| Chemotherapy drug (40) | |
| Macromolecule (10) | |
| Monolayer (79) | |
and the blockbuster chemotherapy drugs that gave you all those nasty side effects will be a thing of the past
Another month in the hospital on intensive chemotherapy drugs did nothing to help. By the time the man started the trial,
Testing their new approach in mice the researchers found that the chemotherapy drug temozolomide (TMZ) was more effective
For the new brain study the researchers delivered chemotherapy drugs via implantable microcapsules made of a biocompatible material called liquid crystal polymer.
because it is so difficult to get chemotherapy drugs to cross the blood-brain barrier. This could potentially positively impact patients lives says Lim who was involved not in the study.
treatment with cisplatin a small-molecule standard-care chemotherapy drug; treatment#with nanoparticles carrying both mir-34a and sikras;
or more different chemotherapy drugs in hopes that a multipronged attack will be more successful than a single drug.
and help doctors predict how a given patient will respond to chemotherapy drugs. The new test, described in the Proceedings of the National Academy of Sciences the week of April 21, can analyze four types of DNA repair capacity simultaneously, in less than 24 hours.
Such a test could also be used to predict patientsresponse to chemotherapy drugs, which often work by damaging cancer cellsdna,
#Resistance is futile Cisplatin is given a chemotherapy drug to more than half of all cancer patients. The drug kills cells very effectively by damaging nuclear DNA but if tumors become resistant to cisplatin they often grow back.
From metals to drugsthe researchers now hope to explore mitochondrial-targeted cisplatin s potential use as a chemotherapy drug by testing it in animals.
It also carries the chemotherapy drug doxorubicin in a prodrug form. The natural fluorescence of the polymer assists with diagnosis and monitoring of therapy as it shows where nanoparticles have accumulated.
and the chemotherapy drug that is released within them (see image). This is the first nanoplatform that can offer on-demand
which could improve the efficacy of existing chemotherapy drugs.""It is important to understand how fork reversal
or for using the eshha technique to detect things like how much of a chemotherapy drug a patient is metabolizing
and then chemically link a liposome sphere filled with a chemotherapy drug. The surface of the nanochain is modified also to penetrate
the team will add inhibitors to traditional chemotherapy drugs. For instance, Rich's lab has shown that inducible nitric acid synthase is a unique signal regulator in glioblastoma stem cells.
and mix of chemotherapy drug and inhibitor, study their effects and effectiveness in mouse models and evaluate the efficacy on human glioblastoma grafts in the models s
as it allows for controlled experiments that don't require flooding a patient's system with experimental chemotherapy drugs,
Normally, in his research on chemotherapy drugs, Theodorescu used a technique called RNAI, which silences various genes,
Normally, in his research on chemotherapy drugs, Theodorescu used a technique called RNAI, which silences various genes,
After initial exposure, the cells surviving the chemo make so much P-gp that it allows the cells to pump the chemotherapy drugs straight back out of the cells during subsequent rounds of treatment."
After initial exposure, the cells surviving the chemo make so much P-gp that it allows the cells to pump the chemotherapy drugs straight back out of the cells during subsequent rounds of treatment."
chemotherapy drug used to treat leukaemia could prevent and control the growth of colorectal tumours. Colorectal cancer commonly referred to as colon cancer is one of the three most common cancers worldwide and the most common in Singapore.
Currently, platinum chemotherapy drugs, like paclitaxel and carboplatin are used as a one-size-fits-all treatment for ovarian cancer patients.
#Graphene-Coated Catheters May Improve Delivery of Chemotherapy drugs The research suggests that placing graphene-an extremely thin sheet of carbon atoms-on the internal surfaces of intravenous catheters commonly used to deliver chemotherapy drugs into a patient's body will improve the efficacy of treatments,
The study indicates that damaging interactions can occur between the most commonly used chemotherapy drug, 5-Fluorouracil (5-Fu),
nobody has looked ever at the chemical reaction between chemotherapy drugs and the materials they routinely come into contact with, such as catheters and needles and their coatings.
"We have shown that silver is catalytically degrading the chemotherapy drugs, which means they are probably not being delivered correctly into the patient.
We will also look to extend our experiments to include other chemotherapy drugs.""Source: http://ioppublishing. org g
When SR9243 is used in combination with existing chemotherapy drugs, it increases their effectiveness, in a mechanism apart from SR9243's own cancer fighting ability, added Dr. Burris B
#Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells (Nanowerk News) Nanoparticles packed with a clinically used chemotherapy drug
and encapsulating the chemotherapy drug doxorubicin can target and kill cancer stem-like cells six times more effectively than free doxorubicin.
or infiltrated by chemotherapy drugs, they find a way to return. The ability of many brain tumors to regenerate can be traced to cancer stem cells that evade treatment and spur the growth of new tumor cells.
and while participants in the trial received flu-like side effects after the first few injections, this was far preferable to the side effects that come with chemotherapy drugs.
While they remain among the most prescribed and most potent chemotherapy drugs, they also cause serious side effects,
'The body's immune system, especially the liver and spleen, has been one of the biggest stumbling blocks in developing nanoscale chemotherapy drug delivery systems,
One hour later, they administered a dose of a platinum-based chemotherapy drug that had been incorporated into a nanoparticle.
showed that only 23 percent of patients lived longer than five years after failing to sustain remission with standard chemotherapy drugs.
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