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wrote the authors of Beyond Therapy, a 2003 report by the US President's Council on Bioethics.
says John Harris, Professor of Bioethics, and Director of the Institute for Science, Ethics and Innovations, University of Manchester, UK.
when they are coming together to form biofilms, a manoeuvre that greatly strengthens their defences against immune-system attacks.
Andraka's research incuding writing to 200 science professors led to him developing a dipstick diagnostic test which searches for a biomarker for pancreatic cancer.
and therefore does not inherently promote biodiversity. We therefore need to think about architecture very differently.
In addition, a flexible approach to architectural design may also help us think about sustainability and biodiversity.
whether the biological marker of neuroinflammation (called translocator protein) that is visible with the new dye would be elevated in regions of the brain that regulate mood.
The innovation is a flexible piezoelectric layer sandwiched between biocompatible plastic. Rogers says the whole system is about as stiff as the plastic used to make food wrappers.
biocompatible prosthetics using small-scale manufacturing techniques. Because the process integrates imaging, design and manufacture, it can build a safe,
or what does the blood biomarkers (blood samples) tell us The database allows neurologists to compare their patientscases with similar ones.
Over-forested and degraded land is threatening the country's wealth of biodiversity. Agricultural lands for olive orchards and other crops are being damaged.
the Cyclon project is developing biocompatible sugar-based drug-delivery systems that could lead to a breakthrough in the fight against various cancers.
The method it uses draws on the body's natural processes of biomineralisation the production of minerals.
these sensors could then clearly identify the disease'biomarkers'the telltale signs of diseased cells.
The presence of the crystals on the electrodes is detected as the signal of the bioassay which,
"Patients who have undergone total prostatectomy may benefit from ultra-sensitive systems that can detect the prostate-specific cancer biomarkers at much lower concentrations
Writing in Nature Nanotechnology, Dr de la Rica and Professor Stevens also state that affordable methods for detecting disease biomarkers at ultra-low concentrations can potentially improve the standard of living in countries lacking costly
and silver ionisation to eradicate biofilm and legionella from water systems. We started this project in 2009 together with our SME partners in The netherlands Greece
The BIFIPRO system releases copper and silver ions into the water to eliminate biofilm a breeding ground for harmful bacteria like legionella.
which is a determining factor in the removal of biofilm and legionella. Mr van der Linde explains that the copper
'In addition, it is biocompatible, which is essential for something that is going to be used in the mouth,
its biocompatibility means it can be used to improve rigidity and friction resistance. Furthermore, it has potential applications in the auto industry and in the area of safety,
#Eurobioref#How a radical redesign is strengthening economic viability in the bioeconomy Fotolia 2012the word bioeconomy has existed only since the late 1990s.
and painlessly scan the skin of a subject s palm accurately measures changes in a biomarker known as skin carotenoids in response to an intervention involving a diet enriched in fruits and vegetables.
##There is great interest in the development of objective biomarkers of dietary intake especially biomarkers that can be measured noninvasively##says coauthor Susan T. Mayne professor of epidemiology at Yale university and a developer of the device.##
and fruit and vegetable intakeâ##this new paper demonstrates that the biomarker was sensitive to changes in fruit and vegetable intake in the intervention setting.##
Her group studies the biomechanics of heart valves particularly their calcification or hardening a condition that lessens blood flow to the heart.
and some smart bioinformatics allows us to detect and characterize the bacteria that cause TB in a matter of a day
##Our study has two crucial applicable findings##says lead author Charles A. Baillie an internal medicine specialist and fellow in the Center for Clinical Epidemiology and Biostatistics at Penn Medicine.##
The findings will be presented at the International Joint Conference on Biometrics on Oct 2. The Bill & Melinda Gates Foundation funded the project.
Hong says. e could also label different neuron types in the brain with biomarkers and use this to monitor how each neuron performs.
and hypertension by picking up airborne biomarkers exhaled or released through the skin. ach of these diseases has its own biomarkers that the device would be able to sense,
says Sherman Fan, professor of biomedical engineering at University of Michigan. or diabetes, acetone is a marker, for example.
Other biomarkers it could detect include nitric oxide and oxygen, abnormal levels of which can point to conditions such as high blood pressure, anemia,
These nanoelectronic graphene vapor sensors can be embedded completely in a microgas chromatography system which is the gold standard for vapor analysis,
The entire microgas chromatography system can be integrated on a single chip with low power operation, and embedded in a badge-sized device that can be worn on the body to provide noninvasive and continuous monitoring of specific health conditions. e believe this device can be extremely beneficial to society,
because they hope it will yield a biological marker to prioritize bipolar disorder care to those who need it most urgently to stabilize their moodsspecially in regions of the world with scarce mental health services.
Pickles is now on the trail of a human biomarker that would tell doctors if an RSV-infected infant is at greater risk of developing severe lung disease.
A biomarker would be key in the development of a needed diagnostic tool and would aid clinical trials that aim to develop anti-RSV therapeutics.
Pickles has already found candidate molecular biomarkers that indicate if the epithelial cells in the tiniest airways are expressing the RSV NS2 protein.
He is now initiating studies to look for the same biomarkers in human infants infected with RSV f we can find biomarkers informing us that the most vulnerable parts of the lung have already been infected by RSV,
and painlessly scan the skin of a subject s palm accurately measures changes in a biomarker known as skin carotenoids in response to an intervention involving a diet enriched in fruits and vegetables.
and adults alike. here is great interest in the development of objective biomarkers of dietary intake especially biomarkers that can be measured noninvasivelysays coauthor Susan T. Mayne professor of epidemiology at Yale university
and fruit and vegetable intake#this new paper demonstrates that the biomarker was sensitive to changes in fruit
In the new study biogeochemists at Rice conducted side-by-side tests of the water-holding ability of three soil types#sand clay and topsoil#both with and without added biochar.
The Geobacter biofilm encased by a network of nanowires and slime gives the bacteria a shield
As the biofilm concentrates many nanowires around the Geobacter cells more uranium can be mineralized bound
which surrounds the biofilm cells and boosts the Geobacter s pili armor so the biofilm now can pull double duty by helping mineralize uranium.
The shield keeps the uranium from penetrating deep into the Geobacter biofilm. By keeping this process on the surface of the film the bacteria are exposed not to uranium
and as a community they are able to clean up more toxic waste. he results surpassed our most optimistic predictionsreguera says. ven thin biofilms immobilized uranium like sponges.
They reduced it to a mineral all while not suffering any damage to themselves for prolonged periods of time. ven
when exposed to extremely high and toxic concentrations of uranium levels that would destroy individual Geobacter cells the biofilms didn t just survive they thrived she adds.
Reguera s future research will focus on deciphering how the biofilm matrix that encases the cells shields them so effectively
For example it could be used to reproduce complex structures such as bone producing a scaffold out of biocompatible materials on
and others. he rapeseed genome has a very interesting historysays Haibao Tang a senior scientist of bioinformatics. s a result of the merger event it ended up with four copies of each gene.
The findings will be presented at the International Joint Conference on Biometrics on Oct 2. The Bill & Melinda Gates Foundation funded the project.
NIR-IIA imaging might offer a means of better understanding the role of healthy vasculature in those diseases Hong says. e could also label different neuron types in the brain with biomarkers
and hypertension by picking up airborne biomarkers exhaled or released through the skin. ach of these diseases has its own biomarkers that the device would be able to sensesays Sherman Fan professor of biomedical engineering at University of Michigan
. or diabetes acetone is a marker for example. ther biomarkers it could detect include nitric oxide and oxygen abnormal levels
of which can point to conditions such as high blood pressure anemia or lung disease. Fan is developing the sensor with Zhaohui Zhong an associate professor of electrical and computer engineering and Girish Kulkarni a doctoral candidate in electrical engineering.
These nanoelectronic graphene vapor sensors can be embedded completely in a microgas chromatography system which is the gold standard for vapor analysis the researchers say.
The entire microgas chromatography system can be integrated on a single chip with low power operation and embedded in a badge-sized device that can be worn on the body to provide noninvasive and continuous monitoring of specific health conditions. e believe this device can be extremely beneficial to societyfan says.
and moths and create an extensive ree of Lepidoptera. esearchers also discovered that some insects once classified as moths are actually butterflies meaning there are more butterfly species that previously thought. his project advances biodiversity research by providing an evolutionary foundation for a very diverse group of insects with nearly 160000 described
Using next-generation sequencing a method used to rapidly process large amounts of DNA scientists developed an initial sample of 46 species that represent many of the most biodiverse groups of moths and butterflies.
which is used now in the medical field to detect biomarkers in the early stages of disease.
Volman suggests the material would make a compelling competitor to recently touted nanotube-based aerogels for deicing airplanes in the winter. e have the technology;
and analyzed their chemical compositions using gas chromatography-mass spectrometry. Finally the researchers presented the gland extracts to worker bees
The scientists fear that implementing genetic solutions could potentially deter other climate change action. serious concern is that even the possibility of using genetic-engineering tools to rescue biodiversity will encourage inaction with regard to climate change.
Before genetic engineering can be entertained seriously as a tool for preserving biodiversity conservationists need to agree on the types of scenario for which facilitated adaptation managed relocation
Other available features include a human/machine interface (HMI) touch-screen display with GPS and biometric data logging, ipod integrated sound systems,
Currently, produce warehouses use expensive technologies such as gas chromatography or mass spectroscopy to measure ethylene levels,
200 or so that gas chromatography or mass spectroscopy systems currently run at. Another system, developed at the UK's National Physical Laboratory, uses radio frequencies, microwaves, terahertz radiation and far-infrared light to determine the ripeness of strawberries
GEDI's 3d maps could be combined with maps from other satellites to examine the role forest architecture plays in biodiversity and land use,
Gelatin is biocompatible biodegradable and classified as#Generally Recognized as Safe#by the Food and Drug Administration.
a government agency that protects and conserves the country biodiversity, and struggled to find enough resources to cope with last year fires. hat is most frustrating is that
to make the device more biocompatible. The idea was to develop an artificial heart in which the moving parts that are in contact with blood are made of tissue that is better suited for the biological environment,
the Iot also enables more acute exploitation of biometric tech, like#RFID chips that users carry with them on their persons;#
Tracking of patients data through wearables and biometric sensors.##Healthcare providers can tell if the health of a patient at home is declining,
Livestock biometrics: Collars with GPS, RFID and biometrics can automatically identify and relay vital information about the livestock in real time.
Scientifically viable in 2017; mainstream and financially viable in 2020. Crop sensors: Instead of prescribing field fertilization before application,
The paper may have more relevance for our understanding of biogeochemical cycles internal to the oceans.
They have coaxed bacterial cells to produce biofilms that incorporate nonliving materials, essentially creating"living materials"that can be integrated into everyday objects and devices, from solar panels to adjustable furniture,
for the research because it naturally produces biofilms that contain so-called"curli fibers, "which are amyloid proteins that attach to surfaces.
Researchers then programmed the E coli cells to produce biofilms with the conducting properties of gold nanowires.
thus having the ability to change the composition of their biofilms over time.""It a really simple system but what happens over time is you get curli that increasingly labeled by gold particles.
and biofilms with enzymes that catalyze the breakdown of cellulose could be used for the conversion of agricultural waste into biofuels.
computational biologist Richard Green, is coordinating the analysis of the genome's 3 billion base pairs.
"On the other hand, having an easily accessible biomarker for glioma would give you a clear response. There are 18 U s. hospitals participating in the clinical trial,
says Sudhir Srivastava, head of the National Cancer Institute s Cancer Biomarkers Research Group.""Exosomes could be very much more cancer specific.
PSA might give you one specific biomarker for cancer identification, but exosomes can give you an entire disease specific profile
Researchers use the kit to look for the genetic biomarker TMPRSS2: ERG or T: E in exosomes taken from a urine sample.
and also has biomarkers which are positive in exosomes that would be a great test,
but the impact on biodiversity and ecosystems has received little attention until now, says Bawa. Native to the meadows of The himalayas and Tibetan plateau at 3
led by Nick Goldman of the European Bioinformatics Institute (EBI) at Hinxton, UK, marks another step towards using nucleic acids as a practical way of storing information#one that is more compact and durable than current media such as hard disks or magnetic tape.#"
#Flesh-eating flies map forest biodiversity The blowflies and flesh flies that settle on dead animals aren't just feasting on the carrion#they're sampling their DNA.
but soon realized"that detecting mammal DNA from flies could also be an extremely cool tool for assessing biodiversity,
aims to be accessible to people with no expertise in bioinformatics, and provides access to free tools for designing custom-made analysis pipelines.
when bioinformaticians started up a flurry of companies, most of which were unsuccessful because the path from a genetic-disease marker to a profitable drug has not been straight#forward.
Biocompatible: This sort of goes without saying, but anything implanted with the body has to be entirely non-reactive, especially in the brain.
so a polymer that is both flexible and biocompatible is perfect for neural implantation. Multiple functionalities:
Could biometric payment methods replace credit cards altogether? Researchers from Tsinghua University and Tzekwan technology, a financial security protection firm, have announced the first ATM that works with facial recognition capabilities, reports the South China Morning Post.
The United states currently does not use this kind of ATM biometric technology but Baltimore Securityplus Federal Credit union did run a trial for a machine that used facial recognition tech
the researchers write in the study introduction. acial expressions are a sensitive, specific biomarker of the presence and severity of pain,
and operations for the first five years the center will fuel collaborations at the junction of clinical practice basic research computational biology
For the new brain study the researchers delivered chemotherapy drugs via implantable microcapsules made of a biocompatible material called liquid crystal polymer.
bumpy texture, can quickly remove more than 90 percent of the biological fouling. Zhenan Bao, a professor of chemical engineering at Stanford university who was involved not in this research,
The percentage of time a leg spends on the ground rather than in the air is referred to in biomechanics as a duty cycle;
It s based on a naturally occurring biomarker that does not require any biochemical processing of samples says Han one of the senior authors of a paper describing the technique in the Aug 31 issue of Nature Medicine.
in order to understand disease mechanisms identify potential biomarkers and ignite needed progress in therapeutics. Launched in 2007 by a $100 million commitment from the Stanley Medical Research Institute the Stanley Center has extensive collaborations with investigators at MIT Harvard and the Harvard-affiliated hospitals as well as with investigators around the world.
Science and Systems conference in Berkeley Calif. Biomechanical synergythe robot which the researchers have dubbed supernumerary robotic fingers consists of actuators linked together to exert forces as strong as those of human fingers during a grasping motion.
The researchers hypothesized that a similar biomechanical synergy may exist not only among the five human fingers but also among seven.
here an opportunity to use these multiplexed plasmids in biological assays where several repair pathways can be probed at the same time,
At least among amputees Herr says Biom could help by fitting elderly populations with leg prostheses equal in biomechanical agility and control to a young adult s legs:
and other substances including living cells MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials such as gold nanoparticles and quantum dots.
because it naturally produces biofilms that contain so-called curli fibers amyloid proteins that help E coli attach to surfaces.
These peptides can capture nonliving materials such as gold nanoparticles incorporating them into the biofilms. By programming cells to produce different types of curli fibers under certain conditions the researchers were able to control the biofilms properties
and create gold nanowires conducting biofilms and films studded with quantum dots or tiny crystals that exhibit quantum mechanical properties.
They also engineered the cells so they could communicate with each other and change the composition of the biofilm over time.
First the MIT team disabled the bacterial cells natural ability to produce Csga then replaced it with an engineered genetic circuit that produces Csga
which forms curli fibers that coalesce into a biofilm coating the surface where the bacteria are growing.
The two types of engineered cells can be grown together in a colony allowing researchers to control the material composition of the biofilm by varying the amounts of AHL and atc in the environment.
Cells that talk to each other The researchers also demonstrated that the cells can coordinate with each other to control the composition of the biofilm.
The researchers are interested also in coating the biofilms with enzymes that catalyze the breakdown of cellulose
Lu engineered phages that could break apart antibiotic-resistant biofilms coatings where bacteria live and thrive by injecting bacteria with certain enzymes to make the biofilms self-destruct.
This discovery would earn Lu the $30, 000 Lemelson-MIT Student Prize, in 2008, and a spot on Technology Review 2010 list of top innovators under 35.
Seeing phages as better antimicrobial treatments than antibiotics to which biofilms and bacteria can build immunity Lu, Sample6 cofounder and now vice president of operations Michael Koeris,
where biofilms build up in pipelines before seeing firsthand that the food industry as in desperate need of new detection technologies.
to break apart the biofilms that build up and corrode oil pipelines, or to detect the pathogenic bacteria that sometimes cause oil to sour by changing its composition.
That points to yet another possible application of soft robotics Rus says in biomechanics If you build an artificial creature with a particular bio-inspired behavior perhaps the solution for the engineered behavior could serve as a hypothesis for understanding
of which can trigger release of hundreds of biomarkers that are then easily detectable in a patient s urine.
When we invented this new class of synthetic biomarker we used a highly specialized instrument to do the analysis says Bhatia the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical engineering and Computer science.
and colleagues introduced the concept of a synthetic biomarker technology to amplify signals from tumor proteins that would be hard to detect on their own.
This is a new idea to create an excreted biomarker instead of relying on what the body gives you she says.
The team is also working to identify signatures of MMPS that could be exploited as biomarkers for other types of cancer as well as for tumors that have metastasized.
Stocker says in some cases that phenomenon could lead to new approaches to tuning flow rates to prevent fouling of surfaces by microbes potentially averting everything from bacteria getting a toehold on medical equipment to biofilms causing drag on ship hulls.
One prominent location is near the walls of tubes where the result is a strong enhancement of the bacteria s tendency to adhere to those walls and form biofilms.
But this effect varies greatly depending on the speed of the flow opening the possibility that the rate of biofilm formation can be tweaked by increasing or decreasing flow rates.
Biofilms are found everywhere Rusconi says adding that the majority of bacteria spend significant fractions of their lives adhering to surfaces.
Bacteria concentrated in biofilms are up to 1000 times more resistant to antibiotics than those suspended in liquid.
and idea owing to the major importance of bacterial biofilms The research was supported by the National Science Foundation and by a Gordon and Betty Moore Marine Microbial Initiative Investigator award to Stocker r
The robot, developed by the team at MIT Newman Laboratory for Biomechanics and Human Rehabilitation, has mainly been used as a rehabilitation tool:
and also provide a new toolkit from which one can develop other novel bioassays, Doyle says.
Hogan and his colleagues in the Newman Laboratory for Biomechanics and Human Rehabilitation have measured the stiffness of the ankle in various directions using a robot called the nklebot.
Biometric sensors are getting smaller and the ease with which data can be analyzed and shared is improving.
biometric sensors will be featured in 40 percent of smartphones shipped to end users With the way technology is developing and the increasing consumer demand,
Using two biocompatible parts, University at Buffalo researchers and their colleagues have designed a nanoparticle that can be detected by six medical imaging techniques:
"Combining these two biocompatible components into a single nanoparticle could give tomorrow's doctors a powerful,
and prevents attachment and biofilm formation. These pores can be as small as 15 nanometers;
according to a study recently published in the journal Biofouling. The study also investigates how the size of the nanopores changes the repulsive forces on bacteria."
"Anodized metals could be used to prevent buildups of biofilms slick communities of bacteria that adhere to surfaces
a recently discovered urinary antigen and a potential biomarker for bladder cancer. The new tool could be used as a high-throughput screening platform to identify patients at risk of developing the urologic condition.
the SERS-based bioassay has two practical advantages: the low-volume sample requires no purification prior to testing
Scientists identify this certain biomarker that is specific to a certain tumor then conjugates this biomarker on the surface of the nanocarrier that only has the expression for that specific kind of cancer cell.
The nanotech carriers go into the body through a vein in the blood stream seek the abnormal cancer cells find the biomarker
This material is biocompatible and biodegradable and can potentially stay in the tumor cells until its job is finished then dissolve
#Next generation biomarker detects tumour cells and delivers anticancer drugs Nanyang Technological University (NTU) has invented a unique biomarker with two exceptional functions.
First it lights up when it detects tumour cells to allow scientists to take a better look.
This new biomarker which has immense potential for drug development is made from a nanophosphor particle ten thousand times smaller than a grain of sand.
Our new biomarker has eliminated effectively such key limitations which exist in existing biological markers. The breakthrough has resulted in two papers published in Small one of the world's top scientific journals for material science and nanotechnology.
Prof Loo said their new biomarker can#also release anticancer drugs by creating a layer of coating loaded with drugs on the outside of the nanoparticle.#
#The drugs are released when the biomarker lights up in response to the near-infrared light. This is the first time we are able to do bio-imaging
and potentially target the delivery of drugs at the same time as proven in small animal tests said Prof Loo a nanotechnology and bioimaging expert.
The new biomarker also has other advantages. It has twice the contrast of conventional dyes
Unlike other new biomarkers used for imaging such as quantum dots the NTU biomarker has also been shown to be nontoxic staying in the body for up to two days before it is passed out harmlessly.
Moving forward the team from NTU's School of Materials science and engineering will be looking to load multiple layers of drugs into their biomarker.
If successful doctors will be able to release sequentially two or more drugs through the biomarker.#
and also higher efficacy as the biomarker has the ability to accurately target tumour cells.
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