#New Technology for Blood-Free Glucose Sensing The University of Leeds may have solved one of the biggest holy grails in medicine,
Currently, finger pricking is the daily grind of diabetics worldwide, which also involves careful pipetting of the blood samples into the glucometer.
In a small scale clinical study at the Leeds Institute of Cardiovascular and Metabolic Medicine, the technology has shown considerable promise to be able to match currently used glucometers.
while the ipod touch is for the patient to control the level of therapy throughout the day.
#Tiny Remote Controlled Implant Releases Drugs Into Brain The blood-brain barrier is a picky bouncer, preventing most therapeutic compounds from crossing its barricades.
To get around this challenge and to be able to treat a variety of neurological conditions,
researchers from Washington Universityin St louis and the University of Illinois at Urbana-Champaign have developed a wireless implant that can be controlled remotely to release drugs right into the brain.
The device, about the width of human hair, is soft and flexible, and contains four tiny drug chambers.
Yet, in laboratory studies, the combination of the two factors can help identify which compounds are promising neurological drug candidates.
#Wize Mirror to Monitor Health, Prevent Cardio-Metabolic Diseases Seasoned primary care physicians often have an uncanny ability to notice symptoms by simply looking at their patients.
and help spot signs of cardio-metabolic diseases. There is a 3d scanning camera that notices changes to the structure of the skin,
The devices were placed close to the spinal cord near the lower back of the patients who underwent weekly sessions for about four months to see how they respond to the therapy.
even though the men have complete paralysis, there are still neural connections that remain that are able to take on new functions requested by the body.
which in the past has demonstrated considerable benefits for mice with spinal cord injuries. Toward the end of the study, amazingly the patients were able to move their legs on their own without the neurostimulators doing anything at all.
not only because cheap transcutaneous neurostimulators may be used in treating paralysis due to damaged spinal cords, but more importantly because there clear evidence that such patients may one day recover their natural walking ability thanks to these devices.
A 2014 Gallup poll found that 41 percent of Americans find medical testing on animals to be morally wrong,
#Nanotechnology helps protect patients from bone infection Leading scientists at the University of Sheffield have discovered nanotechnology could hold the key to preventing deep bone infections,
showed applying small quantities of antibiotic to the surface of medical devices, from small dental implants to hip replacements, could protect patients from serious infection.
Scientists used revolutionary nanotechnology to work on small polymer layers inside implants which measure between 1 and 100 nanometers (nm) a human hair is approximately 100,
000 nm wide. Lead researcher Paul Hatton, Professor of Biomaterials Sciences at the University of Sheffield, said:
icroorganisms can attach themselves to implants or replacements during surgery and once they grab onto a nonliving surface they are notoriously difficult to treat
which causes a lot of problems and discomfort for the patient. y making the actual surface of the hip replacement or dental implant inhospitable to these harmful microorganisms,
the risk of deep bone infection is reduced substantially. ur research shows that applying small quantities of antibiotic to a surface between the polymer layers
which make up each device could prevent not only the initial infection but secondary infection it is like getting between the layers of an onion skin. one infection affects thousands of patients every year and results in a substantial cost to the NHS.
Treating the surface of medical devices would have a greater impact on patients considered at high risk of infection such as trauma victims from road traffic collisions or combat operations,
and those who have had previous bone infections. Professor Hatton added: eep bone infections associated with medical devices are increasing in number,
especially among the elderly. s well as improving the quality of life, this new application for nanotechnology could save health providers such as the NHS millions of pounds every year. ource:
http://www. sheffield. ac. uk/news/..e
#World smallest spirals could guard against identity theft Take gold spirals about the size of a dime...
#A stretchy mesh heater for sore muscles If you suffer from chronic muscle pain a doctor will likely recommend for you to apply heat to the injury.
along with an international team, have come up with an ingenious way of creating therapeutic heat in a light, flexible design.
while deformed and under stress on knee and wrist joints. It is lightweight, breathable and generates heat over the entire surface area of the material.
"The researchers used the nanoparticles to attack E coli, a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium;
Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species; and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
"The researchers used the nanoparticles to attack E coli, a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium;
Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species; and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
"said Michael R. Bruchas, Ph d.,associate professor of anesthesiology and neurobiology at Washington University School of medicine and a senior author of the study.
The Bruchas lab studies circuits that control a variety of disorders including stress, depression, addiction, and pain.
Both options require surgery that can damage parts of the brain and introduce experimental conditions that hinder animals'natural movements.
to construct a remote controlled, optofluidic implant. The device is made out of soft materials that are a tenth the diameter of a human hair
"We used powerful nanomanufacturing strategies to fabricate an implant that lets us penetrate deep inside the brain with minimal damage,
"Ultra-miniaturized devices like this have tremendous potential for science and medicine.""With a thickness of 80 micrometers and a width of 500 micrometers, the optofluidic implant is thinner than the metal tubes,
When the scientists compared the implant with a typical cannula they found that the implant damaged
In some experiments, they showed that they could precisely map circuits by using the implant to inject viruses that label cells with genetic dyes.
when they made mice that have light-sensitive VTA neurons stay on one side of a cage by commanding the implant to shine laser pulses on the cells.
"The researchers fabricated the implant using semiconductor computer chip manufacturing techniques. It has room for up to four drugs
"We tried to engineer the implant to meet some of neurosciences greatest unmet needs.""In the study, the scientists provide detailed instructions for manufacturing the implant."
"A tool is only good if it's used, "said Dr. Bruchas.""We believe an open,
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
TUNDERSTANDING defects in materials aids in performance predictions March 18th, 2015'Smart bandage'detects bed sores before they are visible to doctors March 18th,
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015'Smart bandage'detects bed sores before they are visible to doctors March 18th, 2015graphene'gateway'discovery opens possibilities for improved energy technologies March 18th, 2015clean energy future:
2015the Universitat Politcnica de Valncia is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th,
#'Smart bandage'detects bed sores before they are visible to doctors Abstract: Engineers at the University of California, Berkeley, are developing a new type of bandage that does far more than stanch the bleeding from a paper cut or scraped knee.
Thanks to advances in flexible electronics, the researchers, in collaboration with colleagues at UC San francisco, have created a new"smart bandage"that uses electrical currents to detect early tissue damage from pressure ulcers,
or bedsores, before they can be seen by human eyes -and while recovery is still possible.
"We can imagine this being carried by a nurse for spot-checking target areas on a patient,
in the journal Nature Communications, could provide a major boost to efforts to stem a health problem that affects an estimated 2. 5 million U s. residents at an annual cost of $11 billion.
Pressure ulcers, or bedsores, are injuries that can result after prolonged pressure cuts off adequate blood supply to the skin.
Areas that cover bony parts of the body such as the heels, hips and tailbone, are common sites for bedsores.
"said Dr. Michael Harrison, a professor of surgery at UCSF and a co-investigator of the study."
"This bandage could provide an easy early warning-system system that would allow intervention before the injury is permanent.
"Bedsores are associated with deadly septic infections, and recent research has shown that odds of a hospital patient dying are 2. 8 times higher
when they have pressure ulcers. The growing prevalence of diabetes and obesity has increased the risk factors for bedsores."
"The genius of this device is that it's looking at the electrical properties of the tissue to assess damage.
To mimic a pressure wound, the researchers gently squeezed the bare skin of rats between two magnets.
The smart bandage was used to collect data once a day for at least three days to track the progress of the wounds.
reversible tissue damage while three hours of pressure produced more serious, permanent injury. Promising future"One of the things that makes this work novel is that we took a comprehensive approach to understanding how the technique could be used to observe developing wounds in complex tissue,
"said Swisher.""In the past, people have used impedance spectroscopy for cell cultures or relatively simple measurements in tissue.
and extract useful information from wounds developing in the body. That's a big leap."
and as we learn more and more about the responses the body has to disease and injury,
UCSF professor of surgery, is now heading up a clinical trial of this bandage. The project is funded through the Flexible Resorbable Organic and Nanomaterial Therapeutic Systems (FRONTS) program of the National Science Foundation.##
###For more information, please click herecontacts: Sarah Yangwriteemail('berkeley. edu','scyang';'510-643-7741copyright#University of California, Berkeleyissuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
New manufacturing unit increases production capacity 25 fold March 18th, 2015predicting prostate cancer: Nanotechnology shows promise for more accurate prostate cancer screening and prognosis March 17th, 2015'Additive manufacturing'could greatly improve diabetes management March 17th, 2015nanotechnology Drug Delivery Market in the US 2012-2016:
Latest Report Available by Radiant Insights, Inc March 16th, 2015discoveries 30 years after C60: Fullerene chemistry with silicon:
#Predicting prostate cancer: Nanotechnology shows promise for more accurate prostate cancer screening and prognosis Abstract:
A Northwestern University-led study in the emerging field of nanocytology could one day help men make better decisions about
whether or not to undergo aggressive prostate cancer treatments. Technology developed by Northwestern University researchers may help solve that quandary by allowing physicians to identify which nascent cancers are likely to escalate into potentially life-threatening malignancies and
which ones will remain"indolent,"or nonaggressive. The prostate specific-antigen antigen (PSA) test was recommended once the screening tool for detecting prostate cancer,
but there is now disagreement over the use of this test because it can't predict which men with elevated PSA levels will actually develop an aggressive form of the disease."
"If we can predict a prognosis with our technology, then men will know if their cancer is dangerous
and if they should seek treatment, "said Vadim Backman, senior author of the study.""Right now there is no perfect tool to predict a prognosis for prostate cancer.
Our research is preliminary, but it is promising and proves that the concept works.""Backman is a professor of biomedical engineering at Northwestern's Mccormick School of engineering and Applied science.
Northshore University Healthsystem (Northshore) and Boston Medical center, was published online in PLOS ONE. Backman has been studying cell abnormalities at the nanoscale in many different types of cancers,
using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy. PWS can detect cell features as small as 20 nanometers,
This is the first study to use PWS to predict a cancer prognosis, the likely course of the disease.
Prostate cancer is the second-leading cause of cancer deaths in American men, but doctors also say it is often overdiagnosed and overtreated.
By age 80, more than 50 percent of men will develop prostate cancer but not all will have the aggressive,
deadly form of the disease. However, because their prognosis is unknown, many opt for aggressive treatments that have side effects that cause urinary,
bowel and erectile dysfunctions and more.""The goal is to find specific biomarkers of aggressive cancers,
"said Charles Brendler, MD, Co-Director of the John and Carol Walter Center for Urological Health & Program for Personalized Cancer Care at Northshore and author of the study."
"These biomarkers will allow us to individualize our treatment recommendations and improve patient outcomes.""To be able to give a patient a prognosis,
not just identification of risk of tumors, would be said a major advancement Dr. Hemant K. Roy professor of medicine and Chief of gastroenterology at Boston Medical center and an author of the study."
"This approach may allow tailoring of clinical decisions regarding management of patients with prostate cancer,
thus maximizing the benefit and minimizing the harms of therapy, "Roy said. In this study, researchers analyzed prostate tissue biopsies from two cohorts of prostate cancer patients.
The first cohort included eight men with non-progressing cancer and 10 with progressing cancer.
The PWS operator was blinded to the clinical status of the patients. The second cohort was comprised of 10 progressors and 10 non-progressors in
which the PWS investigators were blinded to the entire group. There was a profound increase in nano-architectural disorder in the progressors as compared to the non-progressors.
This assessment may represent a powerful biomarker to predict cancer progression for men with early-stage prostate cancer."
"This study has high quality data because it was done in a blinded fashion, "Backman said.""Given that even in the unblinded dataset the investigator responsible for data acquisition was unaware of the clinical status,
Backman also hopes to use similar techniques to predict cancer progression in ovarian, breast and esophageal cancers.##
###The study authors are Hemant K. Roy of Boston Medical center; Charles B. Brendler, Karen L. Kaul, Brian T. Helfand, Chi-Hsiung Wang, Margo Quinn, Jacqueline Petkewicz and Michael Paterakos, of Northshore University Healthsystem;
News and information'Additive manufacturing'could greatly improve diabetes management March 17th, 2015harris & Harris Group Reports Financial statements as of December 31, 2014 and Posts Annual Letter to Shareholders on Website March 17th, 2015four
2015innovative light therapy reaches deep tumors March 9th, 2015a new tool for detecting and destroying norovirus March 9th,
2015the Universitat Politcnica de Valncia is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th,
2015nanomedicine'Additive manufacturing'could greatly improve diabetes management March 17th, 2015nanotechnology Drug Delivery Market in the US 2012-2016:
Latest Report Available by Radiant Insights, Inc March 16th, 2015silver implant nanotech killing infections: NC State Industrial & Systems Engineering Research Team Arms Implants With Battery-Activated Nanotechnology March 14th, 2015turmeric Extract Applied in Production of Antibacterial Nanodrugs March 12th,
2015discoveries Stable long term operation of graphene devices achieved (Kopie 1 march 17th, 2015maps predict strength of structures:
2015announcements'Additive manufacturing'could greatly improve diabetes management March 17th, 2015harris & Harris Group Reports Financial statements as of December 31, 2014 and Posts Annual Letter to Shareholders on Website March 17th,
which facilitate a charge injection from gold, and n-type organic semiconductors, which facilitate a charge injection from silver (Figure 3). EEJA will announce the research findings relating to this technology at the 62nd Jpan Society of Applied Physics Spring Meeting,
to be held between March 11 and March 14 at Tokai University, Shonan Campus (Hiratsuka-shi, Kanagawa). Background to this technology OFET is a transistor that uses an organic semiconductor,
2015sensors The Universitat Politcnica de Valncia is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th,
2015military The Universitat Politcnica de Valncia is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th,
who are now exploring business opportunities for marketing the classification and determination of the degree of pluripotency of stem cells before their use in cell therapy or research in biomedicine.
thus having the capacity of becoming a standard method of quality control of stem or pluripotent cells before their use in cell therapy or research in biomedicine e
March 10th, 2015photonics/Optics/Lasers Innovative light therapy reaches deep tumors March 9th, 2015quantum sensor's advantages survive entanglement breakdown:
2015the Universitat Politcnica de Valncia is coordinating a European project to develop a device for the quick and early diagnosis of cancer March 7th,
this could be a very promising lead in developing norovirus antiviral therapy. This could be especially beneficial to immunosuppressed individuals such as cancer patients.
Administering a vaccine to protect against infection would overwhelm the patient's immune system. However, if he or she has the option of receiving an antiviral to eliminate the infection,
the norovirus becomes much less dangerous
#Microchip captures clusters of circulating tumor cells--NIH study Circulating tumor cells (CTCS) are cells that break away from a tumor and move through a cancer patient's bloodstream.
Single CTCS are extremely rare, typically fewer than 1 in 1 billion cells. These cells can take up residence in distant organs,
and researchers believe this is one mode by which cancer spreads. Even less common than single CTCS are small groups of CTCS, or clusters.
While the existence of CTC clusters has been known for more than 50 years, their prevalence in the blood as well as their role in metastasis has not been investigated thoroughly,
However, recent advances in biomedical technologies that enable researchers to capture single CTCS have renewed interest in CTC clusters,
. professor of surgery (biomedical engineering) at the Massachusetts General Hospital (MGH) and the Harvard-MIT Division of Health & Sciences Technology, report the development of a novel microfluidic chip that is specifically designed for the efficient capture of CTC clusters
"Very little is known about CTC clusters and their role in the progression and metastasis of cancer.
M d."This is the kind of breakthrough technology that could have a very large impact on cancer research."
which funds transformative technological innovation designed to solve major medical problems with a substantial disease burden,
such as preventing cancer metastasis or precisely tailoring therapeutics to an individual's cancer cell biology. Toner and his collaborator Dr. Daniel Haber, M d.,Ph d.,also at MGH, recently used Cluster-Chip to capture
and analyze CTC clusters in a group of 60 patients with metastatic breast, prostate, and melanoma cancers.
The researchers found CTC clusters--ranging from two to 19 cells--in 30-40 percent of the patients."
and occasionally clusters using antibodies that stick to special proteins found on the surface of some tumor cells.
This latter property makes the Cluster-Chip well-suited for capturing CTC clusters from a range of cancer types,
including those that lose surface proteins during metastasis and those that never express them, such as melanoma.
The researchers went on to test the Cluster-Chip in a small trial of 60 patients with metastatic cancer.
In this study, the chip captured CTC clusters in 11 of 27 (40.7 percent) breast cancer patients, 6 of 20 (30 percent) melanoma patients
and an association between the presence of clusters and reduced survival in prostate cancer patients.
the researchers measured a marker of tumor cell proliferation--an indicator of increased invasiveness and poor outcomes--in one breast cancer patient with high numbers of both single CTCS and clusters.
The researchers also noted the rare presence of non-tumor cells within clusters in less than 5 percent of patients."
"Given the increasing number of cancer therapies that engage the immune system, the ability to monitor tumor-immune cell interactions via the blood could be of great value."
"Toner anticipates that the Cluster-Chip will play an important role in stimulating new research on CTC cluster biology:"
and to develop even better technologies to understand their biology in cancer metastasis
#Computing at the speed of light: Utah engineers take big step toward much faster computers The Utah engineers have developed an ultracompact beamsplitter--the smallest on record--for dividing light waves into two separate channels of information.
New device offers clues Why do some cancer cells break away from a tumor and travel to distant parts of the body?
A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.
2015 Cancer becomes deadly when it spreads, or metastasizes. Not all cells have the same ability to travel through the body,
The differences in individual cancer cells are a key aspect of how cancer evolves becomes resistant to current therapies or recurs."
"A primary tumor is not what kills patients. Metastases are what kill patients. Understanding which cells are likely to metastasize can help us direct more targeted therapies to patients,
"says co-senior study author Sofia D. Merajver, M d.,Ph d.,scientific director of the breast oncology program at the University of Michigan Comprehensive Cancer Center.
The researchers believe this type of device might some day help doctors understand an individual patient's cancer.
Which cells in this patient's tumor are really causing havoc? Is there a large population of aggressive cells?
Are there specific markers or variants on those individual cells that could be targeted with treatment?"
"This work demonstrates an elegant approach to the study of cancer cell metastasis by combining expertise in engineering
"In this work, extensive studies were performed on cell lines representing various types of cancer. The new device was designed to trace how cells move, sorting individual cells by their movement.
and appearance under the microscope of metastatic cells and expressed significantly higher levels of markers associated with metastatic cancer."
"Understanding specific differences that lead some cancer cells to leave the primary tumor and seed metastases is of great benefit to develop
Patients seeking more information about their options for cancer treatment can call the U-M Cancer Answerline at 800-865-1125 5
and even medicine. Now a team of Northwestern University researchers has found a way to print three-dimensional structures with graphene nanoflakes.
The fast and efficient method could open up new opportunities for using graphene printed scaffolds regenerative engineering and other electronic or medical applications.
assistant professor of materials science and engineering at Northwestern's Mccormick School of engineering and of surgery in the Feinberg School of medicine,
"Supported by a Google Gift and a Mccormick Research Catalyst Award, the research is described in the paper"Three-dimensional printing of high-content graphene scaffolds for electronic and biomedical applications,"published in the April
so it could be used for biodegradable sensors and medical implants. Shah said the biocompatible elastomer
2015effective Nano-Micelles Designed in Iran to Treat Cancer May 20th, 2015announcements SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium:
2015effective Nano-Micelles Designed in Iran to Treat Cancer May 20th, 2015environment Nano-policing pollution May 13th, 2015chemists strike nano-gold:
Many thousands of times thinner than the average human hair, nanofibers are used by medical researchers to create advanced wound dressings--and for tissue regeneration
drug testing, stem cell therapies and the delivery of drugs directly to the site of infection.
Nanofibers can also be loaded with proteins, nanotubes, fluorescent materials and therapeutic agents.""We can use almost any kind of polymer with this platform,
2015nanomedicine Effective Nano-Micelles Designed in Iran to Treat Cancer May 20th, 2015nature inspires first artificial molecular pump:
Simple design mimics pumping mechanism of life-sustaining proteins found in living cells May 19th, 2015studying dynamics of ion channels May 18th, 2015organic nanoparticles, more lethal to tumors:
Carbon-based nanoparticles could be used to sensitize cancerous tumors to proton radiotherapy and induce more focused destruction of cancer cells, a new study shows May 18th,
2015effective Nano-Micelles Designed in Iran to Treat Cancer May 20th, 2015materials/Metamaterials Taking control of light emission:
, more lethal to tumors: Carbon-based nanoparticles could be used to sensitize cancerous tumors to proton radiotherapy
and induce more focused destruction of cancer cells, a new study shows May 18th, 2015wearables may get boost from boron-infused graphene:
May 6th, 2015improving Clinical Care and Patient Quality of life in Advanced Liver disease, d-LIVER Workshop, Milan, 27 may 2015 May 6th, 201 0
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