Signs and symptoms

Atrophy (14)
Bleeding (66)
Disability (104)
Fever (40)
Fibrosis (56)
Headache (11)
Malignancy (12)
Preeclampsia (11)
Sclerosis (17)
Sickness (10)
Ulcer (28)

Synopsis: Health: Illness: Signs and symptoms:

epilepsy or intellectual disability (see this review article for further background). But they also can be completely benign

and cancer from benign hyperplasia and prostatitis with an accuracy of 91 percent. Because the method quantifies the inherent chromosomal instability of cancer

Last year, Ye and Karn discovered that one SCFA--butyric acid--induced a chain of events that reactivate the virus associated with Kaposi's sarcoma, the most common malignancy in HIV patients.

Although some agents tested by the military can provide some protection against radiation sickness when taken prior to radiation exposure,

had less cardiac fibrosis, were experienced more active less age-related slowing of their metabolic rate, produced less cholesterol,

It will allow for rapid population-scale DNA sequencing across a broad range of disease areas, focusing on diseases with significant unmet clinical need such as amyotrophic lateral sclerosis (ALS) and idiopathic pulmonary fibrosis.

Unlike slower growing tumors locally advanced prostate cancer is an aggressive malignancy that is prone to metastasize

The study examined close to 600 patients who underwent lumpectomies for non-palpable breast malignancies. It concluded that the utilization of Marginprobe was as much as three times more effective in finding additional cancer on the margins of removed tumor tissue,

says Sebelius. Even beyond the physical disability that amputees suffer, many must also deal with depression, a distorted self-image,

"This can dramatically reduce complications (infections, intracerebral bleeding, etc. because the brain tissue is exposed not directly to any manipulation,

and Developmental Disabilities and was presented at a meeting of the International Meeting for Autism Research.

and 11 as having other##global delay##conditions such as suspected intellectual disabilities Down syndrome or other disorders.

#Fake platelets could keep you from bleeding to death Emory University Georgia Institute of technology rightoriginal Studyposted by John Toon-Georgia Tech on September 9 2014a new class of synthetic platelet

-like particles could give doctors a new option for curbing surgical bleeding and addressing certain blood clotting disorders without the need for transfusions of natural platelets.

or by medics in the military we expect this technology could reduce the number of deaths from excessive bleeding##says Ashley Brown a research scientist at the Georgia Institute of Technologyâ

When they receive the right signals from a protein known as thrombin these precursors polymerize at the site of the bleeding.

##For a patient with insufficient platelets due to bleeding or an inherited disorder physicians often have to resort to platelet transfusions

If the findings published in the Journal of Investigative Dermatology hold up in future human studies the treatment might also speed skin healing in people with skin ulcers extensive burns and battlefield injuries.##

Professor Leann Tilley from the University of Melbourne says the test could make an impact in large-scale screening of malaria parasite carriers who do not present the classic fever-type symptoms associated with the disease. n many countries only

but a leading cause of long-term disability in adults. Therefore, prevention is the best strategy,

ranging from cardiac hypertrophy to neuropathic pain. The compound looks quite powerful for a number of conditions.

but is known not to cause sickness. In prior studies, the researchers tested the virus on a variety of breast cancers that represent degrees of aggressiveness and on human papillomavirus-positive cervical cancer cells.

Researchersinterests in these networks have grown enormously over the past decade as the networks have been tied to many different aspects of brain health and sickness, such as schizophrenia, autism and Alzheimer disease.

Ischemic stroke patients are at risk of bleeding into the brain when there is damage to the barrier.

however, there is already too much damage to the blood-brain barrier and the drug causes bleeding in the brain, severe injury,

if he or she has visible bleeding before administering tpa. Leigh says his computer program, working with an MRI scan, can detect subtle changes to the blood-brain barrier that are otherwise impossible to see.

and fever. ut since these drugs inhibit all prostanoids, each may contribute differently towards the immunity against influenza virus,

#Scientists find off switch for scleroderma Researchers have identified a signaling pathway that switches on scleroderma,

chairperson of the department of pharmacology and toxicology in the College of Osteopathic Medicine at Michigan State. here are two kinds of scleroderma, localized and systemic,

Localized scleroderma affects the skin and causes a loss of flexibility. Systemic sclerosis can spread throughout the body,

hardening organs such as the lungs, heart, gut, and kidneys. Scleroderma is an autoimmune disorder. It estimated 300,000 Americans suffer from the disease with about one-third of those having the systemic form.

Localized scleroderma patients usually live normal lifespans. Yet about half of systemic patients especially with widespread skin involvement and internal organ fibrosis, will see their lives cut short.

Scleroderma many pathways he majority of drug treatments that exist today for fibrosis basically look at reducing just the inflammation,

says Dinesh Khanna, associate professor of internal medicine at the University of Michigan. here are other drugs that block one or two of the signaling pathways that cause the disease,

but scleroderma has many of these pathways. Published in the Journal of Pharmacology and Experimental Therapeutics, the new research could significantly change the quality of life for scleroderma patients

and greatly increase the lifespan of systemic patients, Neubig says. ur research shows promise for the development of a new drug that can reverse the fibrosis process by flipping the main switch on all of the signaling pathways.

By validating this core switch as a viable drug target, we can now continue our work to improve the chemical compounds

so they will work with doses that are appropriate for people. It definitely promising. A donation from Jon and Lisa Rye, a Michigan family who has experienced the effects of scleroderma,

and the family crowdfunding site, the Scleroderma Cure Fund, helped support the research h

#Anticancer drug reverses schizophrenia symptoms in teen mice An experimental anticancer drug appears to reverse schizophrenia-related behavior

and restore some lost brain cell function in young mice with a rodent version of the illness,

which multiple members were blind from birth due to conditions such as Leber congenital amaurosis, cone-rod dystrophy,

Professor Leann Tilley from the University of Melbourne says the test could make an impact in large-scale screening of malaria parasite carriers who do not present the classic fever-type symptoms associated with the disease. n many countries only

which presents symptoms such as a chronic cough coughing up bloody sputum (mucus) fever night sweats and weight loss.

Potential implications of the methodology for human health include for example learning how an infection-induced fever could affect the RNA structures of both humans and pathogens.

At the end of the week, markers of muscular atrophy and inflammation had dropped and the mice had developed even a different muscle type more common in younger mice.

to help those with disabilities better navigate urban streets. Of course, as in the upcoming video game Watch Dogs from Ubisoft, a bad guy could hack into the city and use its monitoring systems in nefarious ways.

our connected devices will be able to monitor our state##inactivity could indicate sickness or depression.

and resources to build some of the bleeding edge mobile computing hardware available today on the cheap.

Is it a headache that there isn just one fast charging standard? You bet. One positive development is the availability of chargers that have wands for both types

including high fever, that is used as a proxy for flu. That estimate is refined then by testing a subset of people with these symptoms to determine how many have flu and not some other infection.

Its estimate for the Christmas national peak of flu is almost double the CDC s (see Fever peaks),

myobundles undergo dose-dependent hypertrophy or toxic myopathy similar to clinical outcomes. Human myobundles provide an enabling platform for predictive drug

#Genetic Brain disorders Converge at the Synapse Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.

and intellectual disability might be useful for many others. In a paper published today in the online edition of Nature Neuroscience,

and intellectual disability disrupt protein synthesis at synapses, and that a treatment developed for one disease produced a cognitive benefit in the other.

Researching the role of fragile X syndrome One heritable cause of intellectual disability and autism is fragile X syndrome,

Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,

Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.

Studies at other institutions have identified mutations in the gene for Syngap associated with autism and intellectual disability.

All three of the disability-associated mutations showed similar effects: Compared to normal neurons, there was less Syngap in synapses

and more likely to experience increased brain atrophy than non-carriers. his study demonstrates that tau deposits in the brains of Alzheimer disease subjects are not just a consequence of the disease,

The leading cause of disability in the United states it affects millions and most often strikes patients while they are young and otherwise healthy.

In people with a disease called retinitis pigmentosa, cones slowly atrophy, eventually causing blindness. Friedrich Miescher Institute scientists Botond Roska and Volker Busskamp have shown previously that some vision can be restored in mice by engineering those cone cells to express light-sensitive proteins.

and kidney fibrosis Bhatia says. The research was funded by the Koch Institute Frontier Research Fund the Kathy and Curt Marble Cancer Research Fund the Mazumdar-Shaw International Oncology Fellows Program the Burroughs Wellcome

2015 SHARE Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.

and intellectual disability might be useful for many others. In a paper published today in the online edition of Nature Neuroscience

and intellectual disability disrupt protein synthesis at synapses, and that a treatment developed for one disease produced a cognitive benefit in the other.

Researching the role of fragile X syndrome One heritable cause of intellectual disability and autism is fragile X syndrome,

Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,

Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.

#Research team developing injectable treatment for soldiers wounded in battle Internal bleeding is a leading cause of death on the battlefield,

incompressible injury one where it is difficult if not impossible to apply the pressure needed to stop the bleeding he

and wound healing in older patients by using nanoparticles that can target where clots are forming without triggering unwanted bleeding.

Those infected suffer from severe fevers, chills, and a flu-like illness. In severe cases, malaria causes seizures, severe anemia, respiratory distress, and kidney failure.

and internal bleeding contains gadolinium a rare-earth metal. Recently biomedical researchers have found ways to increase the effectiveness of certain contrast agents by associating them with nanoparticles.

One chiral form of Thalidomide worked as an effective treatment for morning sickness in early pregnancy,

These arrays have tremendous potential to improve the quality of life for people with many kinds of disabilities.

It also doesn't make use of any bleeding-edge technology. Instead it puts together neurorobotics software

A fun, affordable mealtime assistant for people with upper limb disabilities Shaped like a baby elephant Hellospoon is intended a robot to help children

An Interview with Conor Russomanno Brain-computer interfacing (BCI) is a rapidly growing field that offers huge potential for many applications such as medical grade BCIS to help people with sensory-motor disabilities.

along with giving those with disabilities a hope for the future. To keep up to date with NCCR Robotics please sign up to ourâ monthly infoletter

#OAK, a Kinect-based active support system for the severely disabled OAK which stands for bservation and Access with Kinectis a software application for use by people with severe disabilities.

unicorn fever has raised fears of a bubble in the private equity markets.""You have a frenzy of investors looking for the next Facebook.

which in one chirality alleviates morning sickness in pregnant women and in the other causes birth defects.

he won stop bleeding until he intravenously injects enough of this protein. And treatment is incredibly expensive around $300, 000 per patient per year,

"Given the impact of atrophy on astronauts in space, I wondered if a suit like the one worn by Freeman could fool the body into thinking it was on the ground rather than in space,

bleeding, pain or affect a patient's ability to open their mouth fully. Tennant and colleagues, including graduate student Abed Anjrini,

Amorphous Nanoparticles from Wide Material Range Before Ibuprofen can relieve your headache, it has to dissolve in your bloodstream.

New york. The Jamboxx was designed originally for people with disabilities and enables individual creative expression by allowing users to control a number of music

but will also undoubtedly empower those with disabilities to move beyond current artistic limitations and take advantage of this unique technology

many of whom have disabilities, are able to feel empowered and can enjoy countless hours creating music with their Jamboxx,

while giving back to those who may have physical disabilities, but with the right tools, are

#Nanofiber Hydrogel Infused with Snake Venom May Quickly Stop Bleeding A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice university scientists.

This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem

Tests showed the new material stopped a wound from bleeding in as little as six seconds, and further prodding of the wound minutes later did not reopen it.

"We think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in

Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, are disorders of unknown etiology that are characterized often by abdominal pain, diarrhea, bloody stool, fever,

#Researchers Identify a New Culprit Behind Fibrosis An international team of researchers has identified a new molecule involved in skin fibrosis,

The new study is the first to investigate the role of this molecule in skin fibrosis

The study reveals a new mechanism for the development of fibrosis in skin tissues and could potentially be relevant to other organs that develop fibrosis such as the lungs, heart,

liver and kidney, said researchers. The team led by bioengineering professor Shyni Varghese at the University of California, San diego and Colin Jamora,

a biologist at the IFOM-instem Joint Research Laboratory in India, published the findings in the Oct 15 issue of Nature Communications. ee identified a new component that hasn previously been studied as a factor contributing to fibrosis,

said Varghese. his discovery gives us a new understanding of how fibrosis forms and could help us develop therapeutic strategies that are more effective than existing ones. ibrosis is a condition in which tough,

Due to the development of tough, fibrous matter, fibrosis causes the affected tissues to stiffen, swell, and eventually lose their normal functions.

The exact mechanism by which fibrosis develops is understood not yet clearly, and there are no proven cures or treatments for the disease.

In this study, researchers discovered that a molecule called fibulin-5 played a role in the development of skin fibrosis in mice.

and little is known about its contribution to fibrosis. Since a large component of connective tissue is made of collagen,

most research on the underlying cause of fibrosis has focused so far on the overproduction of collagen.

By focusing on elastin, the team discovered that the development of fibrosis in skin tissues was linked to a particular molecule:

fibulin-5. Researchers studied mice that were engineered genetically to develop skin fibrosis and found substantially higher levels of fibulin-5 in their skin tissues than in normal mice.

High levels of fibulin-5 were also found in the skin tissues of human patients with skin fibrosis.

Researchers also demonstrated that removing fibulin-5 from the genetically engineered mice before they developed skin fibrosis helped prevent all the symptoms of skin fibrosis including skin tissue inflammation

and stiffening from occurring. anipulating the fibulin-5 levels could be a therapeutic strategy to treat skin fibrosis,

and determine whether fibulin-5 plays a role in fibrosis development in other organs besides the skin.

Scleroderma Foundation, and core funds from instem and IFOM r

#Discovery Could Lead to Better Recovery After Stroke UCLA researchers have identified a molecule that, after a stroke,

which is the leading cause of serious long-term disability in adults. The five-year study, performed in an animal model,

#Self-propelled Powder To Stop Bleeding Created, University of British columbia Researchers UBC researchers have created the first self-propelled particles capable of delivering coagulants against the flow of blood to treat severe bleeding,

a potentially huge advancement in trauma care. leeding is the number one killer of young people,

Traditional methods of halting severe bleeding are not very effective when the blood loss originates inside the body like the uterus,

gas-generating calcium carbonate micro-particles that can be applied in powder form to stop critical bleeding.

the particles proved highly effective in stopping the bleeding. While much more rigorous testing and development is needed to bring the agent to market

'When there is scar tissue in the heart or fibrosis, this can cause part of the wave to slow down.

rising to 52 per cent for drivers suffering from angina-chest pains caused by the heart.

'When there is scar tissue in the heart or fibrosis, this can cause part of the wave to slow down.

Patients may suffer anemia, uncontrolled bleeding and vulnerability to infections. Parents often see their children struggle with swollen lymph nodes, painful enlarged spleens, fatigue and anxiety.

which these mutations are acquired to allow the malignancy to thrive and overcome therapy.""Wu and her team collected tumor and normal tissue samples from 538 patients with CLL, 278 of

or writing information on a memory chip is done within a single memory cell, without bleeding over into neighboring cells.

and, in rare cases, can cause bleeding or infection in the eye,"said Sidman. Furthermore, he added,

The resulting decrease in blood cells causes symptoms such as anemia, uncontrolled bleeding, and infection. Few effective and well-tolerated therapies exist to manage these chronic autoimmune issues.

It a calculus of success. Working together, we can solve the equation w

#Boeing Patents Futuristic Force field Aerospace and defence firm Boeing BA-1. 59%has just been granted a patent for

Glu got its biggest recent winner from a celebrity app that many scoffed at before Kardashian game fever swept America.

the University of Toronto is working with Christian Blind Mission a non-governmental organization that helps people with disabilities in developing countries as well as software supplier Autodesk ADSK+0. 17%and the Corsu rehabilitation hospital in Mpigi, Uganda.

I felt this discombobulating headache at the American Authors concert. My friend was sending emails while

#Genetic Variance Found as Cause for Cerebral palsy Cerebral palsy (CP) is the most common form of physical disability in children, with an incidence rate of approximately two cases for every 1, 000 live births.

"Finding an underlying cause for a child's disability is an important undertaking in management,

"Cerebral palsy (CP) is the most common form of physical disability in children, with an incidence rate of approximately two cases for every 1, 000 live births.

"Finding an underlying cause for a child's disability is an important undertaking in management,"stated Dr. Shevell."

) Chronic Disease And Disability A surprising fact is that, nowadays, fewer than 4%of people are completely free of any health problem,

The number of years lived with disability have increased in almost every country, attributable to the growth of chronic diseases such as cardiovascular and respiratory diseases, cancer, back pain, mental health disorders, dementia, road injuries, HIV

Researchers tested Virocap on the blood and stool samples of a small group of children with unexplained fevers.

When we did a study of kids with fever, for example, one patient in that study had a virus we never would have looked for in the blood.

People with unexplained fevers are prescribed also often antibiotics if a virus can be detected. Wylie says Virocap could potentially cut down on the overuse of antibiotics.

If the glasses shift, for instance, optical aberrations disrupt the viewing, potentially causing headache, fatigue, and nausea.

#Snake Venom-infused Hydrogel Stops Bleeding A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice university scientists.

This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem

Tests showed the new material stopped a wound from bleeding in as little as six seconds, and further prodding of the wound minutes later did not reopen it.

""We think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in

#Another Fatal Brain Disease May Come from the Spread of'Prion'Proteins A rare and fatal brain disorder called multiple system atrophy (MSA) may be caused by a newly discovered prion, a protein similar to the ones

"and refers to its ability to bore through a person's intestines and into the liver and other organs, causing ulcers, internal bleeding and chronic diarrhea.

"and refers to its ability to bore through a person's intestines and into the liver and other organs, causing ulcers, internal bleeding and chronic diarrhea.

we discover that the migration defects of fibroblasts from human venous leg ulcer patients can be reversed by ultrasound,

because the risk of serious bleeding is too high, he said i

#Aluminium could give a big boost to capacity and power of lithium-ion batteries One big problem faced by electrodes in rechargeable batteries,

Next, focusing on nonalcoholic steatohepatitis (NASH), the researchers found eightfold increases in potency when animals were treated with SNAS and a 30 percent greater reduction in the animals'fibrosis score.

and chronic skin ulcers, which are a particular problem in the elderly and people with diabetes, said study co-leader David J. Sharp, Ph d.,professor of physiology & biophysics at Einstein.

and can lead to lifelong disabilities. Most often caused by an accident, stroke or disease,

and used in other conditions, such as glaucoma, macular degeneration and corneal ulcers, among others. The research team intends to continue the collaboration between engineering

because the risk of serious bleeding is too high, he said i

#Molecular tinkering doubles cancer drug's efficacy The drug paclitaxel has been used for decades to fight breast, ovarian, lung and other cancers.

including recalcitrant ulcers and burns. The key feature is that the platelets are functional, thus, the system can be used for fundamental and applied studies of the bone marrow. his is an elegant example of how to deconstruct a complex process into its basic elements,

There is a significant burden in cost of care and quality of life for people suffering from this disability.

and tuberous sclerosis 1 and 2). They discovered that a cellular calcium signaling process involving the inositol trisphosphate receptor was altered very much.

although the bleeding had stopped, the woman brain glucose levels had fallen, probably caused by other blood vessels constricting.

The woman was in intensive care after a stroke that involved bleeding on the surface of her brain.

although the bleeding had stopped, the woman brain glucose levels were falling, probably because other blood vessels had constricted.

they found that they could cause a headache or migraine about two hours later. Both peptides widen blood vessels,

which are known to trigger a headache. The pair measured the electrical activity of these neurons in anaesthetised rats

the neurons responsible for a headache no longer surged with activity. hese receptors could genuinely represent a new therapeutic target for migraine,

Compasses and GPS help people without disabilities find their destinations every day, but are of less use to the visually impaired,

#Snake venom helps hydrogels stop the bleeding A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice Univ. scientists.

This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem

Tests showed the new material stopped a wound from bleeding in as little as six seconds and further prodding of the wound minutes later did not reopen it.

What we did was combine it with the hydrogel wee been working on for a long time. e think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in

or stroke every year cannot use the clot-busting treatments administered by paramedics due to the severe side effects that can cause excessive internal bleeding."

which racers with disabilities pilot advanced assistive devices. racks are excellent for this use case

Such patients must avoid eating phenylalanine to prevent problems such as intellectual disability and seizures. Loss of GLDC produces a disorder called nonketotic hyperglycinemia,

and a strong connection was discovered between the suppression of malignancy and the level of the two proteins,

#New transitional stem cells discovered Preeclampsia is a disease that affects 5 to 8 percent of pregnancies in America.

Scientists believe preeclampsia is caused by a number of factors, including shallow placentas that are associated insufficiently with maternal blood vessels.

Now, researchers from the University of Missouri, in an effort to grow placenta cells to better study the causes of preeclampsia,

and his colleagues, says these new stem cells can help advance research on preeclampsia and a number of other areas of the human reproductive process."

what causes diseases like preeclampsia and other prenatal problems.""Embryonic stem cells are pluripotent, meaning they can develop into a number of different types of cells such as muscle cells, bone cells, skin cells, etc.

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