Synopsis: Health: Medicine:


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#Medical diagnosis: Will brain palpation soon be possible? If there is one technique used by the physician to explore the human body during every medical examination

something that greatly complicates the work of neurosurgeons. On the other hand, the brain is the seat of natural vibrations created by the blood pulsating in the arteries and the circulating cerebrospinal fluid.

such as for analysing the development of neurodegenerative processes, the impact of a lesion from a trauma or tumour, response to treatment, etc e


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Aiming for the clinic The development of LRA is the product of a collaboration led by Tripathi and Dr. Rami Kantor, associate professor of medicine in the Warren Alpert Medical school.

assistant professor of medicine and a co-author on the paper. he next steps are to continue the development of LRA


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said David H. Sachs, director of the TBRC Laboratories at Massachusetts General Hospital, the Paul S. Russell Professor of Surgery Emeritus at HMS and professor of surgical sciences at Columbia


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Professor Gavin Giovannoni, Chair of Neurology at QMUL Blizard Institute, said: he phase III ocrelizumab results for both PPMS and RMS,


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from the Cambridge Institute of Medical Research at the University of Cambridge, said: e are starting to find that many forms of blood cancer can be traced back to defects in the basic housekeeping processes in our cellsmaturation.


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the Selma and Herman Seldin Professor of Medicine. t does something that other components don do,

Holtzman and lead author Yong Zhang, Phd, an instructor in pulmonary medicine, suspect that the researchersone-two punch against the virus may explain the large difference in survival rates between control mice


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He is now an assistant professor of medicine in the Division of Nephrology at the University of Washington and a UW Medicine researcher. nswering this question


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The hydrogel may be most useful for surgeries particularly for patients who take anticoagulant drugs to thin their blood. t interesting that you can take something so deadly

This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem

The substance used for medicine is produced by genetically modified bacteria and then purified, avoiding the risk of other contaminant toxins.

What we did was combine it with the hydrogel wee been working on for a long time. e think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in


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Dr. Albert J. Becker from the Institute of Neuropathology of the University of Bonn. The hippocampus, located in the temporal lobe, is a central switching station in the brain.

together with scientists from the departments of Experimental Epileptology and Neuroradiology of the University of Bonn Hospital as well as from the Hebrew University in Jerusalem (Israel), have decoded now a signaling pathway

Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn. The researchers also see a possible potential in this new technology for novel diagnostic approaches in humans.


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Hooks said. t the deadliest gynecologic cancer. Most women with ovarian cancer will have their tumors come back. ithin two years,

reviews over five years worth of research on RGS10 and was published in Future Medicinal Chemistry.

Hooks and Murph tested cells to see how they would react to common chemotherapy medicines.


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since team of scientists from the RIKEN Center for Integrative Medical science (IMS) and other institutions in Japan and Europe have found a relatively simple way to keep immune cells in a multipotent stem cell-like state.


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and there are currently no targeted therapies available. ersonalised medicine is about targeting treatment to an individual particular genetic profile,

and others suggests that in all gynaecological cancers both Ror1 and Ror2 may be expressed over and is important for disease progression.


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Now, a team of researchers from Duke university have shown that these gene-controlling methods are capable of the high degree of precision required for basic science and medical research.

cardiovascular disease, neurodegenerative conditions and diabetes, which can be driven by mutations in control regions of the genome.

Crawford, associate professor of pediatrics, has spent more than a decade developing techniques to identify control regions across the genome


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The discovery was published electronically in the journal Ophthalmology. his is the culmination of more than 20 years of work,

and certain in the long term. s a public research university working to solve some of society greatest health and medical challenges,

says Jean Robillard, M d.,interim president of the University of Iowa and vice president for medical affairs, University of Iowa Health care s


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and programs in the UCLA department of neurology. he brain has limited a capacity for recovery after stroke,


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said Robert Mckenna, Ph d.,a professor of biochemistry and molecular biology in the UF College of Medicine,


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San diego, have developed a method that cuts down by half the time needed to make high-tech flexible sensors for medical applications.

Coleman team at UC San diego has been working in medical settings for four years. Their sensors have been used to monitor premature babies, pregnant women,

patients in Intensive care units and patients suffering from sleep disorders. Coleman and colleagues quickly found out that nurses wanted the sensors to come in a peel-and-stick form,


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Such structures have been investigated for various medical applications but because they do not like water, they do not travel well in bodily fluids.


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Their findings are detailed in a new paper published in the journal Science Translational Medicine.

The team, led by Jérôme Kalifa, M d.,Ph d.,a cardiologist and U-M Medical school assistant professor at the Center for Arrhythmia Research,


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along with Dr. Samie Jaffrey, professor of pharmacology at Weill Cornell Medicine. Jun Zhou, a postdoctoral research associate in Qian lab, is the paper first author.


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He holds a joint appointment in UCSF Diabetes Center and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research.


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Another real-world use for magnetic field cloaking would be medicine. Magnetic resonance imaging or MRI, utilizes magnetic fields. A cloaking device for magnetic fields could make it easier for doctors to utilize MRI during operations by idingthe field from surgical instruments. hat just one application.


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making them useful for applications in drug discovery and toxicology. This study was supported by CREST program of Japan Agency for Medical Research and development,

and Grants-in-Aid for Scientific research of Japan Society for the Promotion of Science f


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Ph d.,study author from the Department of Biomedicine, at the University of Bergen in Bergen,


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Clinical Director of the Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, said:


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surgery and radiotherapy often fail to remove aggressive tumour cells and the brain tumour can grow back. his research shows that we can improve imaging of brain tumours,

which could help both surgeons and radiotherapists with more effective treatment. Professor Charlie Swanton, NCRI chair and Cancer Research UK scientist at the Francis Crick Institute, said:

Being able to delineate the edges of brain tumours is an exciting step towards better surgery and radiotherapy for patients.


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a Swiss transplant surgeon in Geneva. He said he would transplant a genetically engineered pig organ into a patient today,

complete with a surgical theater and a helipad so organs can be whisked where they are needed.

leading transplant surgeons have been meeting with Revivicor ever few months to plan what genes they like to see added next.

or 100 iterations. et surgeons credit the genetically enhanced pigs with some recent successes. Muhammad Mohiuddin,

a transplant surgeon and researcher at the National Heart, Lung, and Blood Institute, in Bethesda, Maryland, says a heart from one of Revivicor pigs lasted two and a half years inside a baboon.

That is because surgeons still need to completely replace a baboon heart with one from these pigs

but lungs are very difficult. ransplant surgeons say one of the largest obstacles they face is the immense cost of carrying out xenotransplant experiments.

A single transplant surgery costs $100, 000 and involves eight people. Then there the cost of keeping the primates, the red tape of animal regulations,


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Schultz thinks there will be medical uses of synthetic organisms long before they are released into the environment to eat oil

Schultz says. think medicine is one area of pretty obvious applications. d


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#Transplant Surgeons Revive Hearts After Death Transplant surgeons have started using a device that allows them to eanimatehearts from people who have died recently,

and use the organs to save others. The eart in a boxis a wheeled cart with an oxygen supply, a sterile chamber,

In at least 15 cases, surgeons in the United kingdom and Australia say they have used the system to successfully transplant hearts removed from patients after theye died.

surgeons at St vincent Hospital in New south wales described three cases in which they waited as little as two minutes after a person heart stopped before they began removing it.

Without such help, surgeons consider hearts from dead donors too damaged to use. he device is vital.

says Stephen Large, a surgeon at Papworth Hospital in the United kingdom, which has used the system as part of eight heart transplants.

Transplant surgeons recognize two major categories of death. People can be brain dead, or they die

a transplant surgeon at the Massachusetts General Hospital. arm is the way to go with metabolically active tissue.

But surgeons found that hearts that stop naturally often didn start again, or can pump blood,

says Large, the Papworth surgeon. The crisis is particularly severe in the U k, . where handguns and some other firearms are prohibited,

the ethical dilemma is how long surgeons should wait before swooping in to retrieve organs. In the U s.,the accepted standard is five minutes,

although Colorado surgeons in 2008 took hearts from brain-damaged newborns after waiting only 75 seconds.

Robert Truog, a medical ethicist at Harvard university, says a question is whether these donors are given really dead


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says Robert Kirsch, a biomedical engineer at Case Western. He also directs the Cleveland FES Center,

says that nine months ago surgeons implanted two bunches of silicon electrodes, called Utah arrays, into the volunteer motor cortex.


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whereas stimulation with ultrasound will require no such surgery. his is said noninvasive, Chalasani. t the first demonstration of this genetic enhancement of ultrasound neurostimulation,


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with potential medical uses. his may even find use in biomedical applications, such as cardiac surgeryhe says. thin-whiskered catheter tip could be used during surgery to track the relative position inside the heart,

potentially reducing the risk of injury, or atrial fibrillation. t


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#Epilepsy drug is approved first FDA 3d printed pill The first 3d printed pill has been approved for use by the US Food and Drug Administration (FDA.


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the researchers believe it has a wide range of potential applications, from consumer electronics and medical sensing devices,


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Surgery Training Centre, both at the Chinese University of Hong kong, attempting to mimic the movement of the larval amphibians to design a capsule endoscope with a controllable swimming action that doctors can steer around inside the stomach to provide a guided tour,


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including non-fouling medical tools and devices such as scalpels and implants, as well as nozzle heads for 3d printing.


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a development with applications ranging from surgical scopes to security cameras to capture a broader perspective at a fraction of the size required by conventional lenses.


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but only medical staff be that doctors, nurses or other medically trained personnel can become erified In the same way Twitter blue tick verifies that a user is who they say they are,

Dr Vikas Shah a consultant radiologist at University Hospitals Leicester. upload radiology cases such as x-rays or CT SCANS with a question or two,

borders, medical specialities and grades. The app is popular with medical students and forms part of their adoption of social media and the new smartphone and tablet tools that are increasingly being used in hospitals,


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Could ractor beamtechnology be a reality in medicine? e can move bigger and heavier objects than we have done,

the scientists see medical applications as a priority for the technology. t could be used to manipulate kidney stones, clots,


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German-based Roche diagnostics is dedicated to driving personalized and preventative medicine, and with the severity of diabetes on the forefront of focus, Roche, in partnership with SAP, created new preventative care package.


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but the potential benefits that can come from adopting on-demand IT in medical research are truly life-changing,

cloud technology is vital to the medical world. On-demand IT cuts costs and increases healthcare options,


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According to the American Congress of Obstetricians and Gynecologists, roughly 14-23 percent of women will struggle with symptoms of depression at some point during their pregnancy.

because research suggests that children of women who experienced depression during pregnancy have a higher risk of becoming depressed as adults (JAMA Psychiatry).


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and provide the medical standards of 37 countries. Source: ZDNET Korea (zdnet. co. kr) window. console && console. log && console. log("ADS:


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but some hospital administrators have come to view them as the first must-have robot tech in a health care industry that's bracing for big changes with the imminent arrival of robot cleaners, diagnosticians, surgeons, and nurses."


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The results are published this week in The New england Journal of Medicine. The new data which builds on preliminary findings presented at the American Society of Hematology's annual meeting in December 2013 include results from the first 25 children and young adults (ages 5 to 22

) treated at the Children's Hospital of Philadelphia and first five adults (ages 26 to 60 treated at the Hospital of the University of Pennsylvania.

Their cancers were so aggressive they had no treatment options left said the study's senior author Stephan Grupp MD Phd a professor of Pediatrics in Penn's Perelman School of medicine and director of Translational Research in the Center

Shannon Maude MD Phd an assistant professor of Pediatrics and a pediatric oncologist at CHOP and Noelle Frey MD MSCE an assistant professor of Medicine and an oncologist at Penn's Abramson's Cancer Center

The research team is led by Carl June MD the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the Abramson Cancer Center

In July 2014 the U s. Food and Drug Administration granted CTL019 its Breakthrough Therapy designation for the treatment of relapsed and refractory adult and pediatric ALL a step

and review of new medicines that treat serious or life-threatening conditions if a therapy has demonstrated substantial advantages over available treatments.


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Collaborators and co-corresponding authors of the paper at Illinois include Timothy Fan associate professor veterinary clinical medicine;


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Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.


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Researchers at Duke Medicine have found a way to kill prostate cancer cells by delivering a trove of copper

Andrew Armstrong M d. associate professor of medicine was involved with a recent study at Duke testing disulfiram in men with advanced prostate cancer.

The above story is provided based on materials by Duke Medicine e


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#Earths magnetic field could flip within a human lifetime Imagine the world waking up one morning to discover that all compasses pointed south instead of north.


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Achim Weber from Zurich University Hospital and Dr. Monika Wolf Institute of Surgical Pathology University Hospital Zurich.

The initial studies are already under way in the preclinical model.**Metabolic syndrome: a combination of obesity/abdominal adiposity insulin resistance raise levels of lipids in the blood and raised blood pressure.


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At least if they live in central neighbourhoods with good access to medical services and public transit infrastructure they will not suffer so much from the loss of automobility.


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and study algae which have the genomic repertoire that make them relevant in their capacity to drive advances in human medicine.

In terms of human medicine this discovery gives scientists a promising new model to study tumor suppression and growth.


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Biomedical applications include microfluidic devices that can handle and process very small volumes of liquid such as samples of saliva or blood for diagnostics.


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Fast accurate and affordable DNA sequencing is the first step toward personalized medicine. Threading a DNA molecule through a tiny hole called a nanopore in a sheet of graphene allows researchers to read the DNA sequence;


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Laboratory studies conducted in the University's School of Medical sciences have confirmed that changes in brain water channels over time play a critical role in traumatic brain injury.

One of the serious consequences of traumatic brain injury is an increase in brain moisture content and associated brain swelling which significantly impacts patients'neurological outcomes.


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just as effective as invasive neck surgery for long-term prevention of fatal and disabling strokes reports an international trial led by UCL (University college London) funded by the Medical Research Council and Stroke Association.

The research paper published today in the Lancet was authored by researchers from UCL Basel University Switzerland the London School of Hygiene & Tropical Medicine the University Medical center Utrecht Netherlands Sheffield Teaching Hospitals

or local anaesthetic and surgeons cut open the affected artery to remove the build up and then sew the wound up.

At the moment stenting is used not widely in the UK due to historical uncertainty over its long-term effectiveness says study leader Professor Martin Brown from the UCL Institute of Neurology.

Carotid endarterectomy is a common yet invasive surgery used to treat carotid artery stenosis and is used widely throughout the UK.


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Story Source The above story is provided based on materials by Medical University of Vienna. Note: Materials may be edited for content and length.


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CRISPR activation and interference can be used to understand how specific genes work in cancer regenerative medicine or neurodegenerative disease according to Weissman.


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The team have been awarded Biomedical Catalyst funding from the Medical Research Council (MRC) to take the drug into a clinical trial in multiple myeloma patients scheduled to begin in late 2015.

Professor Guido Franzoso from the Department of Medicine at Imperial College London who led the research said:


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Accumulating evidence suggests that the fructose component of sugar may have a particularly deleterious effect on health explains co-senior author Mark Herman MD of the Division of Endocrinology Diabetes

and Metabolism at BIDMC and Assistant professor of Medicine at Harvard Medical school (HMS). If you feed animals

and measured adds co-senior author Eleftheria Maratos-Flier MD HMS Professor of Medicine in the Division of Endocrinology Diabetes and Metabolism at BIDMC.

To test this hypothesis the researchers led by first author Jody Dushay MD HMS Instructor in Medicine recruited 10 lean healthy study subjects.


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In 2003 the German neuropathologist Heiko Braak presented a theory suggesting that the disease begins in the gut and spreads to the brain.


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and killing it. ee preparing to launch preclinical testing nowgu says. ee very excited about this system


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and create a more uniform shape that we can distribute the dose of radiation through evenly said White director of Breast Radiation Oncology at the Stefanie Spielman Comprehensive Breast Center.


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Researchers characterize new tumor syndrome Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have published their findings that mutations in a gene known as ARMC5 promote the growth of benign tumors in the adrenal glands

Dr. Bruno Allolio) and Cologne (Dr. Michael Kloth) have been published recently in the Journal of Clinical Endocrinology Metabolism.


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Psychiatric illnesses are cited also as a motive and are described in a stigmatizing manner. More complex language and cautious expressions are also the hallmarks of articles about female suicide.

which study leader Brigitte Eisenwort from the University Department of Paediatrics and Adolescent Medicine at the Meduni Vienna explains as follows:

Psychiatric illnesses can be treated. The suicide risk can be reduced as a result. Journalists should therefore take care to present as correct a view as possible of suicidal tendencies

Department of Psychiatry and Psychotherapy at the Meduni Vienna. Story Source: The above story is provided based on materials by Medical University of Vienna.

Note: Materials may be edited for content and length. Journal Reference e


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#Underground caves: Better water supply in karst areas Drinking water is scarce in the Indonesian region of Gunung Kidul.


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But that's not All the team implanted medical-grade tubing and catheters coated with the material in large blood vessels in pigs

but is often a necessary evil in medical treatments where clotting is a risk. Devising a way to prevent blood clotting without using anticoagulants is one of the holy grails in medicine said Don Ingber M d Ph d. Founding Director of Harvard's Wyss Institute for Biologically Inspired Engineering and senior author of the study.

Ingber is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children's Hospital as well as professor of bioengineering at Harvard School of engineering and Applied sciences (SEAS.

whereas medical surfaces are mostly flat and smooth --so we further adapted our approach by capitalizing on the natural roughness of chemically modified surfaces of medical devices said Aizenberg who leads the Wyss Institute's Adaptive Materials platform.

which is used widely in medicine for applications such as liquid ventilation for infants with breathing challenges blood substitution eye surgery and more.

whose specialties range from hematology to immunology surface chemistry and materials science. This really could only happen in a place like the Wyss Institute Ingber said.


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Oct 11 at the American Academy of Pediatrics (AAP) National Conference & Exhibition in San diego. Researchers who designed the biosurveillance system will describe how it can be used to track illness trends

"says Andrew N. Hashikawa, M d.,F. A a. P.,a pediatric emergency physician at the University of Michigan's C. S. Mott Children's Hospital.

who also is assistant professor in the Department of Emergency Medicine, Division of Pediatric Emergency Medicine, at the University of Michigan Medical school.


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When the engineers sought collaborators to test the device in potentially useful applications H.-S. Philip Wong a professor of electrical engineering connected them with Victor Tse a neurosurgeon and consulting associate professor at Stanford School of medicine.

In a separate effort Dr. Michael Mcconnell a professor of cardiovascular medicine used the device to take a wireless pulse reading as a proof of principle that the technology could be applied to pressures having to do with blood circulation.


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The randomized trial was conducted within 18 community-based pediatric primary care practices using a common electronic health record.


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The issue has been tackled by Dagmar Gotthardt and colleagues in the Institute of Pharmacology and Toxicology of the University of Veterinary medicine Vienna (Vetmeduni Vienna.


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His son was moved to an academic medical center where he had surgery and was put on four newer antibiotics.

Since the NIH has fallen victim to congressional gridlock people in the biomedical community are starting to organize on their own.

He points out that the university excels in biomedical research but is losing brilliant ideas in the Valley of Death between the lab and the market.

Led by Provost and Executive Vice chancellor H. Holden Thorp Phd an enterpreneurship team has been convened to redefine what the university does with biomedical discoveries after the peer-reviewed articles are in print.

and development in part because they underpin every part of modern medical practice from surgery to cancer treatment and pretty much everything in between.


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and response system for sepsis developed by Penn Medicine experts has resulted in a marked increase in sepsis identification

A study assessing the tool is published online in the Journal of Hospital Medicine. Sepsis is a potentially life-threatening complication of an infection;


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#Unusual skin cancer linked to chronic allergy from metal orthopedic implant In rare cases patients with allergies to metals develop persistent skin rashes after metal devices are implanted near the skin.

Metal alloys help make orthopedic implants stronger and more durable. But people with sensitivity to these metals which include nickel cobalt

The researchers were alerted to the connection by a patient who had surgery at another hospital to have a metal rod implanted to repair a fractured ankle.

After the surgery the patient developed a skin rash on her ankle near the location of the implant.

which led surgeons at the other hospital to remove it. But the rash persisted and a few years later a rare form of skin cancer known as Marjolin's ulcer developed at the surgical site.

The cancer which had become painful and ulcerated was diagnosed and removed by physicians at Barnes-Jewish Hospital.

and further research on whether physicians should test for metal sensitivity in patients preparing for surgery to get these types of implants.

This model supported cancer development so strongly that some mice developed invasive squamous cell skin cancers similar to the patient's tumor said lead author Shadmehr Demehri MD Phd a dermatologist

but the patient couldn't said Yokoyama the Sam and Audrey Loew Levin Professor of Medicine.


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and medical diagnostic applications.""For example, Tian noted, the plasmonic paper can be used to detect target molecules that serve as indicators for diseases such as kidney cancer."


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"We are now just one preclinical step away from the finish line, "said Melton, whose daughter Emma also has type 1 diabetes.

And Jose Oberholtzer, M d.,Associate professor of Surgery, Endocrinology and Diabetes, and Bioengineering at the University of Illinois at Chicago,

Thus the final preclinical step in the development of a treatment involves protecting from immune system attack the approximately 150 million cells that would have to be transplanted into each patient being treated.

the Samuel A. Goldblith Professor of Applied Biology, Associate professor in the Department of Chemical engineering, the Institute of Medical Engineering and Science,


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