Exposure to arsenic has been linked to a variety of health problems including cancer vascular diseases and low birth weight.
and neck cancer a Saint louis University researcher has found. Preliminary findings of the research were published in the Public library of Science One Journal by Ratna Ray Ph d. associate professor of pathology at Saint louis University.
We wanted to see the effect of the bitter melon extract treatment on different types of cancer using different model systems said Ray who first tested the extract in breast and prostate cancer cells.
but a combination of things--existing drug therapy along with bitter melon--may help the efficacy of the overall cancer treatment Ray said.
Head and neck cancers which account for 6 percent of all cancer cases start in the mouth nose sinuses voicebox and throat.
They frequently are aggressive and often spread from one part of the head or neck to another.
and neck cancer patients Ray said she and her team would need to validate their results with other preclinical models.
These bioactive compounds respectively help to prevent cardiovascular diseases and cancer. This is contained in a study carried out by the University of Barcelona and the CIBEROBN network Spain
Various studies have shown that the intake of carotenoids such as lycopene prevents prostate cancer and the consumption of foods rich in beta-carotene help to reduce the incidence of lung cancer.
Eating a daily amount of 120 grams of sofrito added to pasta for example the total intake of polyphenols is 16 to 24 milligrams per portion
and lead to new treatments said Judith Gasson a professor of medicine and biological chemistry director of UCLA's Jonsson Comprehensive Cancer Center and senior associate dean for research at the Geffen
#Researcher finds potential new use for old drugsa class of drugs used to treat parasitic infections such as malaria may also be useful in treating cancers
PU. 1 is also a member of a large family of related transcription factors known as ETS that is involved in a broader range of cancers and other diseases.
A total of 66485 women from the E3n study (The french Centre of the European Prospective Investigation into Cancer and Nutrition a well-known ongoing epidemiological study) were followed for new diabetes cases over 14 years.
Experts at The University of Texas MD Anderson Cancer Center dispel common myths and share new educational resources to address this persistent challenge.
Still lung cancer remains the number one cancer killer and the leading preventable cause of death in the United states. With the approaching 50th anniversary of the Surgeon general's Report Foxhall and other MD Anderson experts urge the public to take a proactive stance against this pervasive health
Exposure to secondhand smoke at home or work increases a person's risk of heart disease by 25 to 30%and lung cancer by 20 to 30%.
%That's because the amount of cancer-causing chemicals is higher in secondhand smoke than in the smoke inhaled by smokers.
and sharing this knowledge with others are ways to action said Ernest Hawk M d. vice president of cancer prevention and population sciences at MD Anderson.
As part of MD Anderson's Moon shot program to end cancer Hawk and other experts have developed a comprehensive plan that addresses the burden of tobacco use in institutions communities states and nations.
More than 200000 people are diagnosed with lung cancer each year in the United states and about 150000 people die as a result of this disease.
Smoking contributes to almost 90%of lung cancer deaths and 30%of all cancer deaths. Story Source:
The above story is provided based on materials by University of Texas M d. Anderson Cancer Center. Note:
and cancer that these smokers develop so it makes more sense to help them stop smoking explained Williams who recently became chair of New jersey Breathes a coalition working for a tobacco-free New jersey.
#Endometriosis risk linked to two pesticidesa Fred Hutchinson Cancer Research center-led study has found that two organochlorine pesticides are associated with an increased risk of endometriosis a condition that affects up to 10 percent of reproductive
The above story is provided based on materials by Fred Hutchinson Cancer Research center. Note: Materials may be edited for content and length.
#Gene responsible for hereditary cancer found to disrupt growth-regulating cellular pathwaywhitehead Institute scientists report that the gene mutated in the rare hereditary disorder known as Birt-Hogg-Dub cancer syndrome
This is an unexpected finding as some cancers keep this pathway turned on to fuel their unchecked growth and expansion.
And in my view that's an important first step to understanding how it might be involved in cancer.
In the early 2000s scientists determined that mutations in the gene coding for FLCN caused the rare cancer Birt-Hogg-Dub syndrome
Birt-Hogg-Dub syndrome causes unsightly but benign hair follicle tumors on the face benign tumors in the lungs that can lead to collapsed lungs and kidney cancer.
FLCN's dual roles--as a cause of a rare cancer in its mutated form
Low-calcium diets can also trigger human diseases such as osteoporosis rickets and colon cancer. Another major health concern arises from the chloride in KCL
I'm reminded of a recent clinical study that links cadmium intake to an increased risk of breast cancer.
#Maximizing broccolis cancer-fighting potentialspraying a plant hormone on broccoli--already one of the planet's most nutritious foods--boosts its cancer-fighting potential
John Juvik and colleagues explain that diet is one of the most important factors influencing a person's chances of developing cancer.
In fact eating broccoli regularly has been linked to lower rates of prostate colon breast lung and skin cancers.
and found that of the GS break-down products sulforaphane is the major contributor toward enhanced cancer-fighting enzyme levels
Citrus fruits particularly their peels are rich with flavonoids a nutrient in plants that can help prevent diseases in humans such as cancer and cardiovascular diseases.
and coolants in motors and electrical systems but were banned in 1979 in the U s. after studies found that exposure to these compounds caused cancer and other deleterious health effects in animals.
Some studies (of dieldrin) exposure find links to cancer Parkinson's disease and Alzheimer's and some do said not Carpenter.
Their study published today in the Proceedings of the National Academy of Sciences (PNAS) suggests the compound already shown to be safe for humans may protect normal tissues during radiation therapy for cancer treatment
The compound known as DIM (33'-diindolylmethane) previously has been found to have cancer preventive properties. DIM has been studied as a cancer prevention agent for years
but this is the first indication that DIM can also act as a radiation protector says the study's corresponding author Eliot Rosen MD Phd of Georgetown Lombardi Comprehensive Cancer Center.
For the study the researchers irradiated rats with lethal doses of gamma ray radiation. The animals were treated then with a daily injection of DIM for two weeks starting 10 minutes after the radiation exposure.
and platelets--side effects often seen in patients undergoing radiation treatment for cancer. Rosen says this study points to two potential uses of the compound.
DIM could protect normal tissues in patients receiving radiation therapy for cancer but could also protect individuals from the lethal consequences of a nuclear disaster.
Within the European Prospective Investigation into Cancer and Nutrition (EPIC) a cohort was formed of 6384 persons with diabetes and 258911 EPIC participants without known diabetes.
Funding is provided by a grant from the National Cancer Institute at the National institutes of health. The study also is part of the National Cancer Institute's State and Community Tobacco Control Research Initiative.
To read the full study visit here. To find out more about the CPHSS visit cphss. wustl. edu. Story Source:
and eggs and revealed its relationship with cervical and liver cancer in humans. The research won the National Award in Food Science
It explains that both types of cancer can be originated by the ingestion of food contaminated with aflatoxins produced by the fungi Aspergilus flavus and A. parasiticus.
and cervical cancer in humans therefore aflatoxins are a very important factor in triggering this diseases.
This research is the first in the world to report that cervical cancer can also be caused by ingesting aflatoxin contaminated food.
This carcinogenic has also been detected as a trigger of colorectal pancreatic breast and lung cancer. The specialist clarified that Human Papillomavirus is more carcinogenic and prone to trigger cervical cancer than aflatoxins.
The toxins-the researcher said-are in the water soil and airborne the fungi that produce them are an olive green mold that can be found in refrigerators besides they are very resistant to high temperatures.
and prostate cancer to determine if there is an association with aflatoxins. These initiatives are promoted by the PNCTA (National Award in Food Science and Technology.
The hot flash the bane of menopausal women also can affect men who are undergoing hormone therapy for prostate cancer.
Hot flashes occur in approximately 80 percent of men who are undergoing hormone manipulation as treatment for prostate cancer.
The analysis recently published in the'American Journal of Epidemiology'was directed by researchers from ten countries including Spain as part of the European Prospective Investigation into Cancer and Nutrition (EPIC.
The sample analyzed includes 25682 deaths (10438 due to cancer and 5125 due to cardiovascular disease) among the 451151 participants studied over more than 13 years.
nchez P rez director of the Andalusian School of Public health's (EASP) Granada Cancer Registry and one of the authors of the research explains to SINC.
%There is now sufficient evidence of the beneficial effect of fruit and vegetable consumption in the prevention of cancer and other chronic diseases Sá
%With regard to cancer mortality no statistically significant risk reduction was found although it will be necessary to assess this according to specific types of cancer Sá
nchez adds. Nevertheless the expert highlights that given that fruit and vegetable consumption is associated with the risk of certain cancers--colon and rectal stomach lung etc.
--it is to be expected that their consumption will also have a positive effect on mortality due to these tumours.
However some experience chronic inflammation of the stomach or gastritis which can lead to the development of ulcers or cancer.
A new study by a team of researchers at Fred Hutchinson Cancer Research center may help provide some insight.
Research on schooling behavior in fish may seem an odd fit for a cancer research center
The above story is provided based on materials by Fred Hutchinson Cancer Research center. Note: Materials may be edited for content and length.
#Broccoli to fight skin cancer? With skin cancer emerging as one of the world's most prevalent forms of cancer researchers are using every tool at their disposal to fight this disease.
The tool of choice for Sally Dickinson Phd? Broccoli. A diet heavy in cruciferous vegetables such as broccoli sprouts has shown potential risk-reduction properties for colorectal prostate and various other forms of cancer.
Dr. Dickinson's research currently focuses on how sulforaphane--a naturally occurring compound in broccoli with established chemopreventive properties--could possibly be used to help patients reduce their risk for skin cancer.
What sets Dr. Dickinson's research apart? Instead of eating broccoli to unlock the risk-reduction nutrients she's asking patients to apply small doses of sulforaphane to their skin.
and use of sunscreens we're still seeing far too many cases of skin cancer each year Dr. Dickinson said.
We're searching for better methods to prevent skin cancer in formats that are affordable and manageable for public use.
Sulforaphane may be an excellent candidate for use in the prevention of skin cancer caused by exposure to ultraviolet rays.
Dr. Dickinson a research assistant professor in the Pharmacology Department at the University of Arizona and a UA Cancer Center member began investigating broccoli's chemopreventive properties
when it comes to inhibiting cancer-causing pathways (such as the AP-1 protein) while activating chemoprotective genes (such as the Nrf2 gene).
in order to reduce their risk of skin cancer. Sulforaphane is one of the many natural products and pharmaceutical agents being explored for use in topical prevention of UV-induced skin cancers through the Chemoprevention of Skin cancer Program Project Grant headed by Dr. Bowden and UACC Director David Alberts MD.
Dr. Dickinson's research could potentially lead to a day when parents are instructing their children to not only eat their vegetables
The above story is provided based on materials by NCI-Designated Cancer Centers. Note: Materials may be edited for content and length h
or cancer at enrollment were excluded. Results showed that 12198 participants (6. 5%)developed diabetes during the study period.
#Calcium supplements may not prevent bone loss in women with breast cancerwomen undergoing treatment for breast cancer are prescribed widely calcium
and manage osteoporosis an unwanted side effect of breast cancer therapies. However new research from Wake Forest Baptist Medical center finds that the recommended daily doses of these supplements may not prevent loss of bone mineral density (BMD) in these women.
Study author Gary G. Schwartz Ph d. a cancer epidemiologist at Wake Forest Baptist said the purpose of the study was to examine
and Vitamin d supplementation in maintaining skeletal health of women with breast cancer he said. At the doses recommended the data show that these supplements are inadequate to prevent loss of BMD.
and 200-1000 IU Vitamin d the doses commonly recommended do not prevent loss of BMD in women with breast cancer.
Women with breast cancer lose BMD at a higher rate than their healthier counterparts increasing their risk of fractures
because cardiovascular disease is the main cause of mortality in women with breast cancer. There is growing evidence that calcium supplements may increase the risk of heart attack and stroke.
and efficacy of calcium and Vitamin d supplementation in women undergoing breast cancer therapy. The research is supported by the Comprehensive Cancer Center of Wake Forest University Cancer Control Traineeship--NCI/NIH grant R25ca122061.
Story Source: The above story is provided based on materials by Wake Forest Baptist Medical center. Note: Materials may be edited for content and length.
and water as runoff from agricultural fields causes a host of problems including respiratory illness cancer and cardiac disease.
#Higher intake of fruits and vegetables may reduce the risk of bladder cancer in womenuniversity of Hawaii Cancer Center Researcher Song-Yi Park Phd
and vegetables may lower the risk of invasive bladder cancer in women. The investigation was conducted as part of the Multiethnic Cohort (MEC) Study established in 1993 to assess the relationships among dietary lifestyle genetic factors and cancer risk.
Park and her fellow researcher's analyzed data collected from 185885 older adults over a period of 12.5 years
of which 581 invasive bladder cancer cases were diagnosed (152 women and 429 men). After adjusting for variables related to cancer risk (age etc.
the researchers found that women who consumed the most fruits and vegetables had the lowest bladder cancer risk.
For instance women consuming the most yellow-orange vegetables were 52%less likely to have bladder cancer than women consuming the least yellow-orange vegetables.
The data also suggested that women with the highest intake of vitamins A c and E had the lowest risk of bladder cancer.
No associations between fruit and vegetable intake and invasive bladder cancer were found in men.
Our study supports the fruit and vegetable recommendation for cancer prevention said Park. However further investigation is needed to understand
and explain why the reduced cancer risk with higher consumption of fruits and vegetables was confined to only women.
Story Source: The above story is provided based on materials by University of Hawaii Cancer Center. Note:
Materials may be edited for content and length. Journal Reference e
#Toxic nanoparticles might be entering human food supplyover the last few years the use of nanomaterials for water treatment food packaging pesticides cosmetics
#Celery, artichokes contain flavonoids that kill human pancreatic cancer cellscelery artichokes and herbs especially Mexican oregano all contain apigenin
and luteolin flavonoids that kill human pancreatic cancer cells in the lab by inhibiting an important enzyme according to two new University of Illinois studies.
Apigenin alone induced cell death in two aggressive human pancreatic cancer cell lines. But we received the best results
Pancreatic cancer is a very aggressive cancer and there are few early symptoms meaning that the disease is often not found before it has spread.
It is the fourth leading cause of cancer-related deaths with a five-year survival rate of only 6 percent she said.
which led to a decrease in the production of anti-apoptotic genes in the pancreatic cancer cells.
According to Johnson the scientists'in vitro study in Molecular Nutrition and Food Research is the first to show that apigenin treatment can lead to an increase in interleukin 17s in pancreatic cells showing its potential relevance in anti-pancreatic cancer activity.
Pancreatic cancer patients would probably not be able to eat enough flavonoid-rich foods to raise blood plasma levels of the flavonoid to an effective level.
which would certainly help to reduce the risk of cancer she noted. Story Source: The above story is provided based on materials by University of Illinois College of Agricultural Consumer and Environmental sciences.
It's also a potential gateway to new smokers particularly among teens and in emerging/foreign markets according to behavioral scientists at The University of Texas MD Anderson Cancer Center.
and thereby reducing their lung cancer risk. However MD Anderson cancer prevention experts Paul Cinciripini Ph d. director of the Tobacco Treatment Program and Alexander Prokhorov M d. Ph d. head of the Tobacco Outreach Education
Program caution that more research is needed to understand the potential role of e-cigarettes in smoking cessation.
The above story is provided based on materials by University of Texas M d. Anderson Cancer Center. Note:
The research could aid in the development of new drugs that use a similar mechanism as melittin's to attack cancer and bacteria.
People are interested in using these peptides to fight cancer and other diseases in part because organisms cannot change the makeup of their membrane so it would be very difficult for them to develop resistance to such drugs.
#Nanodrug targeting breast cancer cells from the inside adds weapon: Immune system attacka unique nanoscale drug that can carry a variety of weapons
a protein that stimulates the immune system to attack HER2-positive breast cancer cells. The research team developing the drug--led by scientists at the Nanomedicine Research center part of the Maxine Dunitz Neurosurgical Institute in the Department of Neurosurgery at Cedars-Sinai Medical center--conducted the study in laboratory mice with implanted human
breast cancer cells. Mice receiving the drug lived significantly longer than untreated counterparts and those receiving only certain components of the drug according to a recent article in the Journal of Controlled Release.
Researchers from the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai the Division of Surgical Oncology at UCLA and the Molecular biology Institute at UCLA also participated in the study.
HER2-positive cancers--making up 25 to 30 percent of breast and ovarian cancers--tend to be more aggressive
and less responsive to treatment than others because the overactive HER2 gene makes excessive amounts of a protein that promotes cancer growth.
or stop cancers by blocking them in multiple ways. Polycefin is intended to slow their growth by entering cells and altering defined targets.
The new version also stimulates the immune system to further weaken cancers. We believe this is the first time a drug has been designed for nano-immunology anticancer treatment Ljubimova said.
but it appears that the nanobioconjugate may represent a new generation of cancer therapeutics in
which we launch a multipronged attack that directly kills cancer cells blocks the growth of cancer-supporting blood vessels
#Illinois scientists put cancer-fighting power back into frozen broccolithere was bad news then good news from University of Illinois broccoli researchers this month.
In the first study they learned that frozen broccoli lacks the ability to form sulforaphane the cancer-fighting phytochemical in fresh broccoli.
As little as three to five servings of broccoli a week provides a cancer-protective benefit but that isn't true for bags of broccoli that you pluck out of your grocery's freezer she noted.
which is necessary to form sulforaphane the powerful cancer-preventive compound in broccoli she said.
and sell a product that has the cancer-fighting component that it lacked before he said.
and it will retain its cancer-fighting capabilities Dosz said. Jeffery hopes that food processors will be eager to adopt this process
Until they do said she that consumers can spice up their frozen cooked broccoli with another food that contains myrosinase to bring the cancer-fighting super-food up to nutritional speed.
Undergoing a novel care plan he became a teaching case for veterinary oncologists at the Cornell University Hospital for Animals paving the way to combat cancer in large animals.
and laid down in the snow Goldner drove Nemo nearly four hours to Cornell's hospital where the pig was diagnosed with presumptive B-cell lymphoma a blood cancer.
Though little is known about the prognosis for pigs with cancer Nemo has the notable distinction of establishing a precedent giving veterinarians valuable information for helping large animals.
One of her creations gold nanoshells is the subject of several clinical trials for cancer treatment.
The study published in Nature Publishing Group's Scientific Reports looked at the frequency of'micronuclei'--a telltale sign of chromosomal damage (that has been shown by others previously to be linked to cancer) by screening more than 400000 individual cells extracted from urine samples
which has caused devastating health impacts including cancers in many parts of the world. The authors say their work raises considerable concerns about health impacts of consuming high arsenic rice as a staple particularly by people with relatively poor nutritional status--perhaps as many as a few hundred million people.
Increased frequency of these micronuclei has been shown by other groups to be linked to the development of cancers.
#New risk factors for bowel cancerfizzy drinks cakes biscuits chips and desserts have all been identified as risk factors for bowel cancer according to new research.
Scientists reported links with some established risk factors of colorectal cancer#such as family history of cancer physical activity and smoking.
The study#which used data from the Scottish Colorectal Cancer Study#carried out in 2012 builds on previous research into the link between bowel cancer and diet.
The healthy dietary pattern was found to be associated with a decreased colorectal cancer risk while the western dietary pattern was found to be associated with an increased risk.
While the positive associations between a diet high in sugar and fat and colorectal cancer do not automatically imply'cause
and American Cancer Society--were indifferent or skeptical to initiatives of the state and local activists.
Some of the characters involved have worked previously to deny the reality of the hole in the ozone layer acid rain and the link between tobacco and lung cancer.
It's a spectacular finding that by implementing these simple tobacco control policies governments can save so many lives said lead author David Levy Phd professor of oncology at Georgetown Lombardi Comprehensive Cancer Center
and treat diseases such as Alzheimer's Lou Gehrig's and cancer. The study reported this month in the journal Cell verifies a process that scientists knew existed
and cancer also are linked to protein folding disorders. One of the main roles for the molecular chaperones is preventing those protein misfolding events that lead to aggregation
and treat diseases such as Alzheimer's Lou Gehrig's and cancer. The study reported this month in the journal Cell verifies a process that scientists knew existed
and cancer also are linked to protein folding disorders. One of the main roles for the molecular chaperones is preventing those protein misfolding events that lead to aggregation
and we found we could use light to coax them to make more cancer-fighting antioxidants at certain times of day.
Grucza's team evaluated data from an ongoing National Cancer Institute survey that monitors smoking behavior in all 50 states.
Funding for this research comes from the National Institute on Drug abuse and the National Cancer Institute of the National institutes of health (NIH.
It also was supported by grants from the American Cancer Society and the American Foundation for Suicide Prevention.
We've also started exchanging ideas and information with scientists facing related challenges such as herbicide resistance in weeds and resistance to drugs in bacteria HIV and cancer.
This work was supported by National Cancer Institute grant CA-087472. The funders had no role in study design data collection
The study was funded by grant 1r25ca117887-01a from the National Cancer Institute. Co-authors of the study are John Spangler M d. Mara Vitolins Dr. PH. Stephen Davis M. S. Edward Ip Ph d. Gail Marion Ph d. and Sonia Crandall
and colleagues studied tomatoes enriched in anthocyanin a natural pigment that confers high antioxidant capacity The purple GM tomatoes have already been found to prolong the lives of cancer-prone mice
The therapeutic potential of grapefruit derived nanoparticles was validated further through a Phase 1 clinical trial for treatment of colon cancer patients.
and a cancer causing agent found specifically in tobacco smoke--known as NKK--as measured by their metabolites cotinine and NNAL.
and skin cancers and has been associated with other conditions as well including heart disease type 2 diabetes cognitive deficits and adverse pregnancy outcomes.
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