Synopsis: 5. medicine & health: 1. diseases: Diseases: Cancer, neoplasms and tumors: Cancer:


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The research was supported by TRDRP Grant 18st-0201 and National Cancer Institute Grant CA-61021.


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Long-term exposure can lead to the development of different types of cancer as well as serious cardiovascular neurological and other health problems.


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and alternatives to traditional combustible tobacco says Robin Mermelstein director of the UIC institute and principal investigator of the National Cancer Institute-funded study.

The project is supported by the National Cancer Institute one of the National institutes of health under award number P01ca098262.


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the National institutes of health (NIH)# ARP Diet and Health Study the Cancer Prevention Study II-Nutrition Cohort the Multiethnic Cohort the Health professionals Follow-up Study and the Nurses Health Study


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and doughnuts is associated with an increased risk of prostate cancer and the effect appears to be slightly stronger with regard to more aggressive forms of the disease according to a study by investigators at Fred Hutchinson Cancer Research center.

Corresponding author Janet L. Stanford Ph d. and colleagues Marni Stott-Miller Ph d. a postdoctoral research fellow and Marian Neuhouser Ph d. all of the Hutchinson Center

While previous studies have suggested that eating foods made with high-heat cooking methods such as grilled meats may increase the risk of prostate cancer this is the first study to examine the addition of deep frying to the equation.

Eating more than once a week may raise risk Specifically Stanford co-director of the Hutchinson Center's Program in Prostate Cancer Research

and/or doughnuts at least once a week were increased at an risk of prostate cancer as compared to men who said they ate such foods less than once a month.

or more of these foods at least weekly had increased an risk of prostate cancer that ranged from 30 to 37 percent.

Weekly consumption of these foods was associated also with a slightly greater risk of more aggressive prostate cancer.

The researchers controlled for factors such as age race family history of prostate cancer body-mass index

when calculating the association between eating deep-fried foods and prostate cancer risk. The link between prostate cancer and select deep-fried foods appeared to be limited to the highest level of consumption--defined in our study as more than once a week--which suggests that regular consumption of deep-fried foods confers particular risk for developing prostate

cancer Stanford said. Deep frying may trigger formation of carcinogens in food Possible mechanisms behind the increased cancer risk Stanford hypothesizes include the fact that

when oil is heated to temperatures suitable for deep frying potentially carcinogenic compounds can form in the fried food.

They include acrylamide (found in carbohydrate-rich foods such as French fries) heterocyclic amines and polycyclic aromatic hydrocarbons (chemicals formed

For the study Stanford and colleagues analyzed data from two prior population-based case-control studies involving a total of 1549 men diagnosed with prostate cancer and 1492 age-matched

and risk of prostate cancer Stanford said. However deep-fried foods have previously been linked to cancers of the breast lung pancreas head and neck and esophagus.

Because deep-fried foods are eaten primarily outside the home it is possible that the link between these foods

and prostate cancer risk may be a sign of high consumption of fast foods in general the authors wrote citing the dramatic increase in fast-food restaurants and fast-food consumption in the U s. in the past several decades.

The project was supported by the National Cancer Institute and Fred Hutchinson Cancer Research center. Story Source:

The above story is provided based on materials by Fred Hutchinson Cancer Research center. Note: Materials may be edited for content and length.


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and might even prevent cancer. But for the first time scientists have exposed extracts from numerous berries high in those pigments to human saliva to see just what kinds of health-promoting substances are likely to survive

Scientists say that these early findings will contribute to the further development of confectionaries gums and other delivery devices for the prevention and possibly the treatment of conditions such as periodontal disease and oral cancers.

The extent of the pigment degradation in saliva was primarily a function of the chemical structure of a given anthocyanin said Failla also an investigator in Ohio State's Comprehensive Cancer Center and Food Innovation Center.


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Killian and fellow scientists from Rice and the University of Texas MD Anderson Cancer Center co-founded Nano3d Biosciences in 2009 after creating a technology that uses magnetism to levitate


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and vegetable intake and risk of overall breast cancer but vegetable consumption is associated with a lower risk of estrogen receptor-negative (ER-)breast cancer according to a study published January 24 in the Journal of the National Cancer

The intake of fruits and vegetables has been hypothesized to lower breast cancer risk however the existing evidence is inconclusive.

There are many subtypes of breast cancer including ER -and ER positive (ER+)tumors and each may have distinct etiologies.

and are less dependent on estrogen levels than ER+tumors account for only 15-20%of breast cancers large pooled analyses are needed to determine the suspected link to lower ER-breast cancer risk and the consumption of fruits and vegetables.

In order to determine if there is a link between the lowered risk of ER-breast cancers and the intake of fruits and vegetables Seungyoun Jung Sc.

and vegetables and risk of developing breast cancer in each study and then combined the study-specific estimates to generate summary estimates for all studies combined.

and vegetable intake was linked statistically significantly to a lower risk of ER-breast cancer but not with risk of overall breast cancer or risk of ER+breast tumors.

These findings support the value of examining etiologic factors in relation to breast cancer characterized by hormone receptor status in large pooled analyses

because modest associations with less common breast cancer subtypes may have been missed in smaller studies the authors write.

In an accompanying editorial Cynthia A. Thomson Ph d. and Patricia A. Thompson Ph d. both of the University of Arizona Cancer Center write that the findings of the study support the emphasis on greater intake for vegetables

(and to a lesser extent fruit) to lower the risk of ER-breast cancer. However they also write that interpretation of these findings may also be challenged by the known effects of other potential confounders including the aggregation of health behaviors.

The above story is provided based on materials by Journal of the National Cancer Institute. Note: Materials may be edited for content and length h


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along with 83 percent of the colon cancer cells while normal lung cells were unharmed virtually. Taxol was lethal to the cancer cells too

Wusirika thinks the rice callus culture may be attacking cancer with the same sort of plant chemicals that make vegetables so healthy to eat.

We think that's what is killing the cancer. Next Wusirika would like to try the rice callus solution on prostate lung and breast cancer cells the most common types of cancer in the US.

We think it will work with all of them but we need to find out he said.

He also wants to determine which of the compounds released by the rice callus have cancer-killing properties

Or he notes it's possible that the suite of biochemicals found in the callus solution work as a team to fight cancer.


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In one scenario an athlete was given heroic qualities such as working with ill children a commitment to the cause of cancer prevention dedicating his performance to his mother


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and respiratory diseases including coronary heart disease and lung cancer. However until now it has been uncertain whether ETS increases the risk of dementia mainly due to lack of research.


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--and best known for claims that it can help prevent certain cancers--may ease classic behavioral symptoms in those with autism spectrum disorders (ASDS).

He says that studies show that the cells of those with ASD often have high levels of oxidative stress the buildup of harmful unintended byproducts from the cell's use of oxygen that can cause inflammation damage DNA and lead to cancer and other


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Oral HPV-16 is believed to be responsible for the increase in incidence of oropharyngeal squamous cell cancers in the United states. An association between self-reported number of cigarettes currently smoked per day


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#U s. releases 13th Report on Carcinogensfour substances have been added in the U s. Department of health and human services 13th Report on Carcinogens a science-based document that identifies chemical biological and physical agents that are considered cancer hazards for people living

Identifying substances in our environment that can make people vulnerable to cancer will help in prevention efforts said Linda Birnbaum Ph d. director of the National Institute of Environmental Health Sciences (NIEHS) and the National

and it empowers the public with information people can use to reduce exposure to cancer causing substances.

A listing in the report indicates a cancer hazard but does not by itself mean that a substance will cause cancer.

Many factors including the amount and duration of exposure and an individual's susceptibility to a substance can affect

whether a person will develop cancer. One substance added as a known human carcinogensince 1983 ortho-toluidine has been listed in the Report on Carcinogens as reasonably anticipated to be a human carcinogen.

However new cancer studies led NTP to reevaluate and reclassify ortho-toluidine and it is added now to the category of known to be a human carcinogen based on studies in humans showing it causes urinary bladder cancer.

Ortho-toluidine is a synthetic chemical produced in other countries and imported into the United states by several companies in high volumes.

No human studies were identified that evaluated the relationship between human cancer and exposure specifically to 1-bromopropane.

No human studies were identified that looked at the relationship between human cancer and exposure specifically to cumene.


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but dietary quality could be improveda new American Cancer Society study suggests that participants in the Supplemental Nutrition Assistance program (SNAP) previously known as the food stamp program had lower dietary quality scores compared with income eligible nonparticipants.

For their study published in Mayo Clinic Proceedings researchers led by Binh T. Nguyen Phd of the American Cancer Society explored the diet quality of SNAP participants using data from a nationally representative sample of over 4000 adult

The above story is provided based on materials by American Cancer Society. Note: Materials may be edited for content and length.


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and mean that people are likely to be able to enhance their mental wellbeing at the same time as preventing heart disease and cancer.


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Cancer and cardiovascular disease are the leading causes of death among Taiwanese. When Professor Wahlqvist's study began in 1993 there was little apparent concern about dairy foods in contrast to a current belief that they may be harmful to health

and in particular raise the risk of cancer. The study showed such fears to be unfounded. We observed that increased dairy consumption meant lower risks of mortality from cardiovascular disease especially stroke

but found no significant association with the risk of cancer Professor Wahlqvist said. Milk and other dairy foods are recognised as providing a broad spectrum of nutrients essential for human health.


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The study included 26 930 individuals (60%women) aged 45-74 years from the population-based Malmã Diet and Cancer cohort.


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#Manuka honey does not decrease pain of radiation-induced esophagitis for lung cancer patientspatient-reported data indicates that

and causes discomfort is a common and temporary side effect experienced by the majority of lung cancer patients undergoing RT.

so that patients'do not forgo eating maintaining patients'positive nutritional status is vital during cancer treatment.

The randomized phase II trial enrolled 163 lung cancer patients at 13 cancer centers who were undergoing concurrent chemotherapy and RT.


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cigarettes cause cancer beneath the image of an open mouth with a cancerous lesion and rotten teeth or the same image with the words Warning:

Quitting smoking reduces the risk of cancer? The answer depends on how confident you are in your ability to quit according to a study led by researchers at Georgetown Lombardi Comprehensive Cancer Center and published in the journal Nicotine & Tobacco Research.

The research which involved 740 participants and Three d. C. area institutions suggests that a mix of messages might work best to help convince some of the 45 million smokers in the U s. to give up the habit says the study's lead investigator Darren Mays Phd MPH a Georgetown Lombardi

population scientist who specializes in behavioral cancer prevention. The study found that gain-framed messages--those that stressed the benefits in quitting such as quitting smoking reduces the risk of death due to tobacco--were more effective for smokers who believed quitting would be Hard on the other hand loss-framed messages--the ones


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An unhealthy diet is linked closely to cardiovascular disease diabetes and some cancers. Eating a healthy diet is an important part of the strategy to prevent adverse health outcomes.


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#Fighting prostate cancer with tomato-rich dietmen who eat over 10 portions a week of tomatoes have an 18 per cent lower risk of developing prostate cancer new research suggests.

With 35000 new cases every year in the UK and around 10000 deaths prostate cancer is the second most common cancer in men worldwide.

and lifestyle recommendations reduces risk of prostate cancer researchers at the Universities of Bristol Cambridge

and lifestyle of 1806 men aged between 50 and 69 with prostate cancer and compared with 12005 cancer-free men.

The NIHR-funded study published in the medical journal Cancer Epidemiology Biomarkers and Prevention is the first study of its kind to develop a prostate cancer'dietary index

'which consists of dietary components--selenium calcium and foods rich in lycopene--that have been linked to prostate cancer.

Men who had optimal intake of these three dietary components had a lower risk of prostate cancer.

Tomatoes and its products--such as tomato juice and baked beans--were shown to be most beneficial with an 18 per cent reduction in risk found in men eating over 10 portions a week.

Our findings suggest that tomatoes may be important in prostate cancer prevention. However further studies need to be conducted to confirm our findings especially through human trials.

and body weight for cancer prevention published by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR).

Only the recommendation on plant foods--high intake of fruits vegetables and dietary fibre--was found to be associated with a reduced risk of prostate cancer.

As these recommendations are targeted not at prostate cancer prevention researchers concluded that adhering to these recommendations is not sufficient


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which inflammation--not just neuro-inflammation--is a factor such as rheumatoid arthritis Parkinson's and cancer. The research continues


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For example many cancers are heritable and genome prediction can be performed to predict disease risk for a person.


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Giving hope against cancer? The state of Nayarit in Mexico is one of the major producers of soursop (Annona muricata) at national and global level

because in Mexico cancer is a disease that is increasing among the population and scientific research shows that the compounds found in this fruit can encapsulate tumors


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#Eating resistant starch may help reduce red meat-related colorectal cancer riskconsumption of a type of starch that acts like fiber may help reduce colorectal cancer risk associated with a high red meat diet

according to a study published in Cancer Prevention Research a journal of the American Association for Cancer Research.

Red meat and resistant starch have opposite effects on the colorectal cancer-promoting mirnas the mir-17-92 cluster said Karen J. Humphreys Phd a research associate at the Flinders Center

for Innovation in Cancer at Flinders University in Adelaide Australia. This finding supports consumption of resistant starch as a means of reducing the risk associated with a high red meat diet.

The above story is provided based on materials by American Association for Cancer Research. Note: Materials may be edited for content and length.


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The National Science Foundation (NSF) the Welch Foundation the National institutes of health the Gillson-Longenbaugh Foundation and the Cancer Prevention Research Institute of Texas supported the research.


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Exposure to biomass burning particles is associated strongly with cardiovascular disease respiratory illness lung cancer asthma and low birth weights.


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and vegetable consumption is related to a lower risk of death from cardiovascular disease and cancer. However the results are not entirely consistent.

and the United states decided to examine the association between fruit and vegetable intake and risk of all-cause cardiovascular and cancer deaths.

In contrast higher consumption of fruit and vegetables was associated not appreciably with risk of death from cancer.

and vegetables the adverse effects of obesity physical inactivity smoking and high alcohol intake on cancer risk should be emphasised further.


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and lipids resulting in cellular changes that lead to development of diseases such as cancer. They have a domino effect Dalaly said.

of which have the potential to boost the immune system and impact diseases such as cancer and heart disease.


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and even some forms of cancer The World health organization WHO recommends a daily intake of at least 400 grams of fruit and vegetables.


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#Health risks posed by third hand tobacco smokeresearch led by the University of York has highlighted the potential cancer risk in nonsmokers--particularly young children--of tobacco smoke gases

However a new study published in the journal Environment International has estimated for the first time the potential cancer risk by age group through non-dietary ingestion and dermal exposure to third hand smoke.

Using observations of house dust composition they estimated the cancer risk by applying the most recent official toxicology information.

They found that for children aged one to six years old the cancer risks exceeded the limit recommended by the US Environmental protection agency (EPA) in three quarters of smokers'homes and two thirds of nonsmokers'homes.

The maximum risk predicted from the third hand smoke levels in a smoker occupied home equated to one extra cancer case per one thousand population exposed.


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or promoted by oxidative-damage like coronary heart disease stroke and certain cancers. Overall organic crops had 18 to 69 percent higher concentrations of antioxidant compounds.


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cell carcinoma'which describes the appearance of a highly aggressive form of lung cancer. Dairy products feature prominently in the medical lexicon:'


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Benefits of carotenoidswhatâ's more according to the researchers the inclusion of carotenoids in a diet can help to reduce risk of developing diseases such as certain types of cancer heart disease or damage to vision especially those related to an aging population.


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Traveling waves model tumor invasioncell migration which is involved in wound healing cancer and tumor growth and embryonic growth and development has been a topic of interest to mathematicians and biologists for decades.

and Martin Wechselberger study a model describing cell invasion through directional outgrowth or movement in the context of malignant tumors in particular melanoma or skin cancer.


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Oats are now the third largest food staple in China growing in popularity as that country deals with rising rates of cancer diabetes heart disease and intestinal issues.


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Infection can result in anemia kidney failure and bladder cancer. This research shows it may have been spread by the introduction of crop irrigation in ancient Mesopotamia the region along the Tigris-Euphrates river system that covers parts of modern-day Iraq Iran Kuwait Syria

and may also cause bladder cancer We would expect these consequences in ancient peoples to have had a significant impact upon early civilizations in the region says Dr Mitchell.


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Some studies have highlighted their potential cancer protective properties however research looking at the link to endometrial cancer has been inconsistent.

Dr Motoki Iwasaki Epidemiology Division Epidemiology and Prevention Group Research center for Cancer Prevention and Screening National Cancer Center Tokyo Japan and co-author said:


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Grape phenolics serve as anti-inflammatory agents can reduce the risk of certain cancers and help prevent high blood pressure


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and Community Tobacco Control Research (SCTC) Initiative funded by the US National Cancer Institute at the National institutes of health and published in the supplement.


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#Gardens help cancer survivors cope, heal and growa diagnosis of breast cancer in 2010 hit Susan Rossman pretty hard.

A year later a pioneering study at the University of Alabama at Birmingham helped her reclaim her life from cancer's grasp.

I think that cancer can be the worst thing that ever happened to you or it can be a life-changing event--one that you do something with rather than letting it do something to you she said.

For Rossman the key was Harvest for Health a UAB study that paired cancer survivors and master gardeners from the Alabama Cooperative Extension System.

Wendy Demark-Wahnefried Ph d. R. D. is the associate director for cancer prevention and control in the UAB Comprehensive Cancer Center.

She is intrigued by the link between cancer and diet. There is powerful evidence she says that a diet high in fruits

and vegetables is especially beneficial for cancer survivors. We asked the question: If cancer survivors started a vegetable garden would they eat more vegetables?

We found they not only ate more vegetables they also got more exercise. And their physical functioning improved dramatically she said.

since been expanded to many counties surrounding Birmingham along with the Cullman Montgomery Mobile and Dothan areas with support from the National Cancer Institute.

and increased physical function are means to an end--to keep cancer survivors living independently for as long as possible.

Loss of physical function in cancer survivors especially older survivors is a downward spiral so that many times survivors lose the ability to live on their own she said.

I didn't think about cancer every day. Shaddix of Maple Valley Nursery is a gardener not a psychologist;


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which are associated with the image of cancer said lead author Shu-Hong Zhu Phd professor of Family

Although smoking rates among American adults have declined by more than half from 42 percent in 1965 to 18 percent in 2012 tobacco use in the United states is still responsible for nearly one in five deaths according to the American Cancer Society.


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Researchers from the Johns Hopkins Bloomberg School of Public health working with colleagues at several U s. and Chinese institutions used the broccoli sprout beverage to provide sulforaphane a plant compound already demonstrated to have cancer preventive properties

The study was published in the June 9 online edition of the journal Cancer Prevention Research. Air pollution is a complex and pervasive public health problem notes John Groopman Phd Anna M. Baetjer Professor of Environmental Health at the Johns Hopkins Bloomberg School of Public health

Last year the International Agency for Research on Cancer classified air pollution and particulate matter (PM) from air pollution as carcinogenic to humans.

Diets rich in cruciferous vegetables of which broccoli is one have been found to reduce risk of chronic degenerative diseases including cancer.


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In humans cadmium can damage internal organs and cause cancer. At the same time iron is an essential nutrient for plants and humans.


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#Estimated risk of breast cancer increases as red meat intake increases, study suggestsso far studies have suggested no significant association between red meat intake and breast cancer.

and later and many lines of evidence suggest that some exposures potentially including dietary factors may have greater effects on the development of breast cancer during early adulthood.

So a team of US researchers investigated the association between dietary protein sources in early adulthood and risk of breast cancer.

Factors such as age height weight race family history of breast cancer history of benign breast disease smoking menopausal status hormone

Medical records identified 2830 cases of breast cancer during 20 years of follow-up. Putting these real life data into a statistical model allowed the researchers to estimate breast cancer risks for women with different diets.

They estimated that for each step-by-step increase in the women's consumption of red meat there was a step-by-step increase in the risk of getting breast cancer over the 20 year study period.

Specifically the statistical model worked out the number of cases of breast cancer during the total years of follow up for all the women in the study (rate/person years.

For example the model estimated that there would be 493 cases of breast cancer over 306298 person years among women with the lowest intake of red meat.

This compared with 553 cases per 31169 person years among women with the highest intake.

This translated to an estimate that higher intake of red meat was associated with a 22%increased risk of breast cancer overall.

Each additional serving per day of red meat was associated with a 13%increase in risk of breast cancer (12%in premenopausal and 8%in postmenopausal women.

In contrast estimates showed a lower risk of breast cancer in postmenopausal women with higher consumption of poultry.

Substituting one serving per day of poultry for one serving per day of red meat--in the statistical model--was associated with a 17%lower risk of breast cancer overall and a 24%lower risk of postmenopausal breast cancer.

Furthermore substituting one serving per day of combined legumes nuts poultry and fish for one serving per day of red meat was associated with a 14%lower risk of breast cancer overall and premenopausal breast cancer.

The authors conclude that higher red meat intake in early adulthood may be a risk factor for breast cancer

and replacing red meat with a combination of legumes poultry nuts and fish may reduce the risk of breast cancer.

and risk of breast cancer is needed they add. Story Source: The above story is provided based on materials by BMJ-British Medical Journal.


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#Limiting carbs could reduce breast cancer recurrence in women with positive IGF1 receptordartmouth researchers have found that reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women

The study Risk of Breast cancer Recurrence Associated with Carbohydrate Intake and Tissue Expression of IGFI Receptor will appear in the July issue of Cancer Epidemiology Biomarkers & Prevention.

There is a growing body of research demonstrating associations between obesity diabetes and cancer risk said lead author Jennifer A. Emond an instructor in the Department of Community and Family Medicine at the Geisel School of medicine at Dartmouth College.

There are similarities between the biological pathways that underlie all of these conditions and there is some evidence to suggest that over-activation of the insulin/insulin-like growth factor axis which increases the availability of IGF1 in the blood may relate to a poor prognosis among breast cancer survivors.

Receptors for IGF1 have been found in breast tumor tissue and expression of those receptors may contribute to treatment resistance among breast cancer survivors.

Since diet can influence insulin activation the researchers wondered whether diet could impact breast cancer prognosis based on expression of the IGF1 receptor in the primary breast tumor tissue.

Using an unusual approach this study assessed the combined association of two factors implicated in tumor growth--carbohydrate intake

whether activating the insulin/insulin-like growth-factor axis can impact breast cancer Since carbohydrates stimulate the biological pathway that can increase concentrations of IGF1 the researchers focused on carbohydrate intake.

We found an association between increased breast cancer recurrence in women with a primary breast cancer tumor that was positive for the IGF1 receptor

We further found that a decreased carbohydrate intake was associated with decreased breast cancer recurrence for these women.

This is the first study to suggest that it might be possible to personalize recommended diets for breast cancer survivors based on the molecular characteristics of their primary tumor.

and Emond notes that breast cancer survivors should not be concerned about dramatically lowering their carbohydrate intake based on this study.

what type of carbohydrate-containing foods may be the most important foods that breast cancer survivors should limit she said.

Breast cancer survivors should continue to follow a plant-based dietary pattern as suggested by the American Association for Cancer Research and the American Cancer Association


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