Parkinson's disease

Alzheimer's disease (122)
Creutzfeldt-jakob disease (7)
Dyskinesia (3)
Encephalitis (5)
Encephalopathy (6)
Epilepsy (26)
Headache (65)
Meningitis (10)
Myotonia (1)
Paralysis (19)
Parkinson's disease (107)
Poliomyelitis (33)
Tinnitus (3)

Synopsis: 5. medicine & health: 1. diseases: Diseases: Nervous system diseases: Parkinson's disease:

was associated now with lower rates of diabetes, heart disease and, for some, Parkinson s. Local sourdough bread might actually reduce a meal s glycemic load.

say, schizophrenia, Parkinson s, depression or Alzheimer s in the brain, even though there may be no obvious symptoms.#

Indeed, some academics believe using Second life might even help improve motor ability for people with Parkinson s.)

or other brain related diseases, including, potentially, Parkinson s disease, Alzheimer s disease and autism. Answers will be easier to come by in the near future as the declining cost of profiling a person s microbiota renders such tests more routine

including Parkinson s, mild cognitive impairment, ADHD, Tourette s, and schizophrenia. Dan Hurley, author of Smarter:

including Parkinson s, mild cognitive impairment, ADHD, Tourette s, and schizophrenia. Plus it has long been associated with weight loss.

A huge literature says that smoking protects against Parkinson s, she said. It started as a chance observation,

Parkinson s disease. Strangely enough, death due to the neurodegenerative disorder, marked by loss of dopamine-producing neurons in the midbrain,

And therein lies the answer to the mystery of why nicotine could prevent a movement disorder like Parkinson s disease, due to its effects on dopamine.

To put the drug to the test, Quik treated rhesus monkeys with Parkinson s with nicotine. After eight weeks, she reported in a landmark 2007 paper in the Annals of Neurology

Even more remarkably, in monkeys already receiving L-dopa, the standard drug for Parkinson s, nicotine reduced their dyskinesias by an additional one-third.

Studies of nicotine in humans with Parkinson s are supported now under way by the Michael j fox Foundation. Other research suggests the drug may protect against the early stages of Alzheimer s disease.

But what about nicotine as a cognitive enhancer for people without Alzheimer s, Parkinson s or any other brain disease?

#Eating Peppers May Lower Parkinson's Risk Regularly eating peppers may lower the risk of Parkinson's disease a new study suggests.

People in the study who ate peppers two times per week were 30 percent less likely to develop Parkinson's disease than people who ate peppers less than once a week.

or neurons from the damage associated with Parkinson's. In Parkinson's disease up to 80 percent of the neurons that produce a chemical called dopamine which controls muscle function are damaged according to the National Parkinson Foundation.

A neurodegenerative disease Parkinson's causes a range of symptoms. The hallmark signs are tremors slowness of movement stiffness of the arms legs or trunk and problems with balance.

Approximately 1 million Americans have Parkinson's disease reports the National Parkinson Foundation. Each year 50000 to 60000 new cases are diagnosed in the United states. Â The pepper advantage In the study the researchers looked at 490 people who had been diagnosed newly with Parkinson's disease

and compared them with 644 people who did not have the condition. Participants answered a detailed questionnaire about their lifetime dietary habits and tobacco use.

Just 11 percent of those with the disease and 5 percent of people in the control grouphad a family history of the disease which can raise risk.

The researchers found that not only were associated peppers with a reduced risk of Parkinson's but also that the more peppers people consumed the greater the apparent benefit.

or more slashed their Parkinson's risk by about 50 percent compared with those who ate them less than once a week.

While there was some suggestion that tomatoes might also be associated with a reduced risk of Parkinson's it was not clear Searles Nielsen said.

While it is certainly intriguing to think that eating peppers may protect against Parkinson's disease we have to consider that there are other explanations she said.

 It is not clear from this study that family members at risk (those with a family history of Parkinson's) should rush out

and to establish potential benefits in the Parkinson's'at risk'population. Still it can't hurt to include peppers in your diet Searles Nielsen said.

Eating peppers may lower the risk of Parkinson's disease. Follow Myhealthnewsdailyâ on Twitterâ@Myhealth mhnd. We're also onâ Facebookâ &â Google+.

#Pesticides Linked to Parkinson's Risk in People with Specific Gene Several studies have linked pesticides with the development of Parkinson's disease

and now a new study has found a specific gene that may explain why some people are particularly susceptible to developing Parkinson's after exposure to certain pesticides.

Parkinson's disease results from the loss of neurons involved in processing the neurotransmitter dopamine. Researchers had previously found a gene that was involved in dopamine processing

The findings show that for people with certain genes exposure to pesticides may increase the risk of developing Parkinson's disease two to six times the researchers said.

for Gene-Environment Studies in Parkinson's disease. All of this is environmental exposure not occupational exposure. It can be quite harmful.

to find out which genes might be involved in the nerve death that results in Parkinson's and to see

if there was a variant of that gene that could be found in people exposed to pesticides who developed Parkinson's. 10 Things You Didn't Know About the Brain There were four pesticides the researchers found that appear to trigger an effect on enzymes called neuronal aldehyde dehydrogenases (ALDHS)

The researchers then looked at exposure to those four pesticides in a group of 360 people with Parkinson's who lived in central California

but had developed not Parkinson s. They found that pesticide exposure increased the risk of Parkinson s and the risk was increased further among people with a variant of the ALDH2 gene.

Though researchers were able to identify four pesticides that might be responsible for this effect they were not able to identify a specific pesticide as the culprit.

whether a treatment can be created to reduce the susceptibility of certain people to Parkinson's if they have the gene variant.

Can we predict who might develop Parkinson's? Would they want to take meds? These are need questions we to answer Ritz said.

Whey protein supplements can decrease the effectiveness of the Parkinson's drug levodopa. Whey protein supplements may also reduce how much of the osteoporosis drug alendronate is absorbed by the body making the medicine less effective.

& Parkinson's diseases will take place in Barcelona, Spain, and focus on new possibilities for treating the conditions. go. nature. com/jcgygu Â

which is used to treat motor disorders such as Parkinson s disease, and is being tested for some psychiatric conditions.

On 7 Â August, the device maker Medtronic in Minneapolis, Minnesota announced the start of clinical trials for the system, with the first implantation in a person with Parkinson s in Germany.

Parkinson's is the second most common neurodegenerative disorder characterized by death of dopamine-generating neurons in the brain.

Coffee may lower the risk of Parkinson's by 32-60%(19 20 21 22. Bottom line Coffee is associated with a much lower risk of dementia and the neurodegenerative disorders Alzheimer's and Parkinson's.

The liver is a remarkable organ that carries out hundreds of vital functions in the body.

For the first time we have used human stem cells derived from Parkinson's disease patients to show that a genetic mutation combined with exposure to pesticides creates a'double hit'scenario producing free radicals in neurons that disable specific molecular pathways that cause nerve-cell death

Until now the link between pesticides and Parkinson's disease was based mainly on animal studies and epidemiological research that demonstrated an increased risk of disease among farmers rural populations

Research and professor of biology at the Massachusetts institute of technology (MIT) used skin cells from Parkinson's patients that had a mutation in the gene encoding a protein called alpha-synuclein.

Alpha-synuclein is the primary protein found in Lewy bodies--protein clumps that are the pathological hallmark of Parkinson's disease.

Next they reprogrammed all of these cells to become the specific type of nerve cell that is damaged in Parkinson's disease called A9 dopamine-containing neurons

Since several FDA-approved drugs contain derivatives of isoxazole our findings may have potential clinical implications for repurposing these drugs to treat Parkinson's.

and the environment interact to contribute to Parkinson's and other neurodegenerative diseases such as Alzheimer's and ALS.

This can be disorders like Parkinson's disease Alzheimer's disease autism epilepsy and the motor neurone disease ALS.

The pig The SYN1 gene can with its specific expression in nerve cells be used for generation of pig models of neurodegenerative diseases like Parkinson's.

Some studies (of dieldrin) exposure find links to cancer Parkinson's disease and Alzheimer's and some do said not Carpenter.

and chronic movement disorders resembling Parkinson's disease. It is also a developmental toxicant that has been shown to impair fetal development

or other brain related diseases including potentially Parkinson's disease Alzheimer's disease and autism. Answers will be easier to come by in the near future as the declining cost of profiling a person's microbiota renders such tests more routine Mayer said.

or bug and weed killers and solvents is associated likely with a higher risk of developing Parkinson's disease.

or country living and developing Parkinson's in some of the studies said study author Emanuele Cereda MD Phd with the IRCCS University Hospital San Matteo Foundation in Pavia Italy.

For the analysis researchers reviewed 104 studies that looked at exposure to weed fungus rodent or bug killers and solvents and the risk of developing Parkinson's disease.

or weed killers and solvents increased the risk of developing Parkinson's disease by 33 to 80 percent.

and the method of application such as spraying or mixing affected Parkinson's risk said Cereda. However our study suggests that the risk increases in a dose response manner as the length of exposure to these chemicals increases.

The study was supported by the Grigioni Foundation for Parkinson's disease and the IRCCS University Hospital San Matteo Foundation.

Dietary nicotine may hold protective keynew research reveals that Solanaceae--a flowering plant family with some species producing foods that are edible sources of nicotine--may provide a protective effect against Parkinson's disease.

and tomatoes may reduce risk of developing Parkinson's. Parkinson's disease is a movement disorder caused by a loss of brain cells that produce dopamine.

Symptoms include facial hand arm and leg tremors stiffness in the limbs loss of balance and slower overall movement.

Nearly one million Americans have Parkinson's with 60000 new cases diagnosed in the U s. each year and up to ten million individuals worldwide live with this disease according to the Parkinson's disease Foundation.

Currently there is no cure for Parkinson's but symptoms are treated with medications and procedures such as deep brain stimulation.

Previous studies have found that cigarette smoking and other forms of tobacco also a Solanaceae plant reduced relative risk of Parkinson's disease.

or if people who develop Parkinson's disease are simply less apt to use tobacco because of differences in the brain that occur early in the disease process long before diagnosis. For the present population-based study Dr. Susan Searles Nielsen

and colleagues from the University of Washington in Seattle recruited 490 patients newly diagnosed with Parkinson's disease at the university's Neurology Clinic or a regional health maintenance organization Group Health Cooperative.

Vegetable consumption in general did not affect Parkinson's disease risk but as consumption of edible Solanaceae increased Parkinson's disease risk decreased with peppers displaying the strongest association.

Researchers noted that the apparent protection from Parkinson's occurred mainly in men and women with little or no prior use of tobacco

which contains much more nicotine than the foods studied. Our study is the first to investigate dietary nicotine

and risk of developing Parkinson's disease said Dr. Searles Nielsen. Similar to the many studies that indicate tobacco use might reduce risk of Parkinson's our findings also suggest a protective effect from nicotine or perhaps a similar but less toxic chemical in peppers and tobacco.

The authors recommend further studies to confirm and extend their findings which could lead to possible interventions that prevent Parkinson's disease.

Story Source: The above story is provided based on materials by Wiley. Note: Materials may be edited for content and length.

Most diseases of the brain such as Alzheimer's and Parkinson's have shown an increased amount of toxic protein Berries seem to promote autophagy the brain's natural housekeeping mechanism thereby reducing the toxic accumulation said Poulose.

and Parkinson's disease could be reduced according to the findings of a two-year project headed by University of Huddersfield scientist Dr Olumayokun Olajide who specialises in the anti-inflammatory properties of natural products.

which inflammation--not just neuro-inflammation--is a factor such as rheumatoid arthritis Parkinson's and cancer. The research continues

which is known to cause a Parkinson's like harm of mitochondria recovered after the addition of the two substances.

This gene originally thought of as an oncogene has been linked to Parkinson's disease since 2003. Recent studies showed that DJ-1 belongs to a novel glyxolase family.

and thus can prevent the degeneration of neurons implicated in Parkinson's disease. Their experiments proved that both substances are lifesavers for neurons:

It could serve as a protection against Parkinson's and is actually very tasty at the same time! This is why the researchers have filed a patent for their finding.

Many diseases are associated with a decline in mitochondrial activity not only Parkinson's. Thus the researchers believe that the DJ1-products could have a general role in protecting cells from decline.

Parkinson's disease is a slowly progressive disease that affects a small area of cells within the midbrain known as the substantia nigra.

The decrease in dopamine results in one or more of the classic signs of Parkinson's disease that includes:

Parkinson's disease affects about 1. 2 million patients in the United states and Canada. Although 15 percent of patients are diagnosed before age 50 it is considered generally a disease that targets older adults affecting one of every 100 persons over the age of 60.

#Synthetic gene circuits pump up cell signals in study of neurodegenerative diseasessynthetic genetic circuitry created by researchers at Rice university is helping them see for the first time how to regulate cell mechanisms that degrade the misfolded proteins implicated in Parkinson's Huntington

Certain people may be more susceptibleprevious studies have shown the certain pesticides can increase the risk for developing Parkinson's disease.

In a previous study published January 2013 in the Proceedings of the National Academy of Sciences the UCLA research team discovered a link between Parkinson's

and therefore contributed to the development of Parkinson's. In this study UCLA researchers tested a number of other pesticides

and increase the risk of Parkinson's and at much lower levels than those at which they are currently being used said study lead author Jeff Bronstein a professor of neurology

and were two to six times more likely to develop Parkinson's than those without the variant when exposed to these pesticides.

The study compared 360 patients with Parkinson's in three agriculture heavy Central California counties to 816 people from the same area who did not have Parkinson's.

When ALDH does not detoxify DOPAL sufficiently it accumulates damages neurons and increases an individual's risk of developing Parkinson's.

which these environmental toxins contribute to Parkinson's pathogenesis especially in genetically vulnerable individuals said study author Beate Ritz a professor of epidemiology at the Fielding School of Public health at UCLA. This suggests several potential interventions to reduce Parkinson's occurrence

Then the researchers found that those participants in the epidemiologic study with a genetic variant in the ALDH gene were increased at risk of Parkinson's when exposed to these pesticides.

This report provides evidence for the relevance of ALDH inhibition in Parkinson's disease pathogenesis identifies pesticides that should be avoided to reduce the risk of developing Parkinson's disease

and tested to potentially reduce Parkinson's disease occurrence or slow its progression particularly for patients exposed to pesticides the study states.

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