"said principal investigator Eyal Raz, MD, professor of medicine.""The role of camp formation and action in dendritic cells in the induction of allergic response was added really surprising
co-author Paul Insel, MD, professor of pharmacology and medicine.""It suggested to us that this signaling pathway is involved in other immune-related functions."
professor of medicine and a member of the Veteran's Affairs San diego Healthcare System, said"such molecules
Gas sensors or implantable chips for medical applications which can gather information about blood sugar levels
The ability to perform real-time 3d imaging at cellular resolution in behaving organisms is a new frontier for biomedical
The emergence of fluorescent proteins and transgenic techniques over the past 20 years has transformed biomedical research even delivering neurons that flash as they fire in the living brain.
) and Kimara Targoff (assistant professor of pediatrics Department of Pediatrics) all of whom are starting to use the SCAPE system in their research.
In the journal Investigative Ophthalmology & Visual Science, UTHEALTH's Stephen P. Daiger, Ph d, . and his colleagues report their discovery of a new gene tied to retinitis pigmentosa,
"said Richard S. Ruiz, M d.,professor of ophthalmology and holder of the John S. Dunn Distinguished University Chair in Ophthalmology at UTHEALTH."
. and is now a consulting professor of medicine at Stanford began curating a registry of twins for research purposes.
Davis and his associates also observed considerable environmental influence over the quantities of antibodies produced in members of twin pairs who had been vaccinated for influenza in a separate Stanford investigation directed by study co-author Cornelia Dekker MD professor of pediatric infectious disease
and medical director of the Stanford-Lucile Packard Children's Hospital Vaccine Program. While many previous studies have suggested a powerful genetic component in vaccine responsiveness Davis noted that those studies typically were performed in very young children who had undergone not yet the decades of environmental exposure that appears to reshape the immune system over time.
Other Stanford co-authors of the study are Atul Butte MD Phd associate professor of pediatrics (systems medicine) and of genetics;
Kipnis also saluted the"phenomenal"surgical skills of Igor Smirnov, a research associate in the Kipnis lab whose work was critical to the imaging success of the study.
In developing regions where the economy is weak and medical services are limited, global health experts say as many as 200 million women want access to long-term,
The medical simulator includes two training models: a stand-alone replica arm and a layered band that can be worn by health workers who act as"patients"during practice sessions."
Allen also is a lecturer in the School of medicine's Department of Gynecology and Obstetrics. Working with Johns Hopkins Technology Ventures, the students have obtained a provisional patent covering their invention.
published in the journal Science Translational Medicine, is the first step in the use of programmable cells for medical diagnosis.
#Drug-induced tissue regeneration demonstrated by scientists A study led by Ellen Heber-Katz, Phd, of the Lankenau Institute for Medical Research (LIMR), part of Main line Health (MLH),
The study findings were reported in the June 3, 2015, issue of Science Translational Medicine, a peer-reviewed journal of the American Association for the Advancement of Science.
"This remarkable work has vast importance in medicine and surgery and spotlights the diverse and important scientific investigations underway at LIMR,"says George Prendergast, Phd, President and CEO of LIMR."
"We are committed to the quest to discover therapies that make healthy tissue regeneration a possibility in humans
"This means the present method can be utilized as a prescreening test for point-of-care bacterial diagnosis for various applications including medicine and food hygiene.""
whose speed and precision make them useful for cataract and other eye surgeries. A femtosecond is one-quadrillionth,
Schwab, an assistant professor at NYU Langone and its Skirball Institute of Biomolecular Medicine, says similar laboratory test plans are underway for more potent CXCR4 antagonists, most likely in combination with established chemotherapy regimens.
"said co-senior author Kumar Sharma, MD, a professor of medicine and director of the Center for Renal Translational Medicine at UC San diego School of medicine."
"Drawing on collaborative expertise in synthetic chemistry, molecular biology and translational medicine, the team has produced findings with significant potential to reduce inflammation, a critical driver of the devastating consequences of obesity-related diseases,
'said senior author Dr. Richard Wang, assistant professor of dermatology and a member of UT Southwestern's Harold C. Simmons Comprehensive Cancer Center.'
#Single protein causes Parkinson's disease and multiple system atrophy Typical of neurodegenerative disorders is disrupted the communication between brain cells together with a loss of cells in specific brain regions.
and dementia with Lewy bodies (DLB), this protein forms aggregates that cause neurodegeneration.""When alpha-synuclein aggregates accumulate within a brain cell,
fatigue and in many cases can result in a reduction of quality of life, time off work, hospitalisations and surgery.
#Scientists find genetic variants key to understanding origins of ovarian cancer New research by an international team including Keck Medicine of USC scientists is bringing the origins of ovarian cancer into sharper focus.
'said Simon Gayther, Ph d.,professor in preventive medicine, Keck School of medicine of USC, corresponding author of the international genome-wide association study (GWAS).'
'said Andrew Berchuck, M d.,director of gynecologic oncology at Duke university Cancer Institute, and senior author of the study.'
The research was conducted as part of the Collaborative Oncological Gene-environment Study (COGS), launched in 2009 with the goal of determining risks of breast, ovarian and prostate cancer.'
'Co-first author Kate Lawrenson, Ph d. of Keck Medicine of USC believes the research will lead the way to the development of risk prediction strategies followed by clinical interventions with the potential to prevent ovarian cancer altogether,
In a new study published in Restorative Neurology and Neuroscience, researchers report successfully growing multiple brain structures
posters and guides for around 60 different activities. 1 To evaluate the Toolkit's effectiveness, researchers from the London School of Hygiene & Tropical Medicine,
Dr Karen Devries from the London School of Hygiene & Tropical Medicine, said:""What's notable about these results is that we found a very large reduction.
To further improve vaccine immunogenicity at the preclinical stage, we need to immuno-focus the antibody response to only the critical,
"The 24-hour ultra-marathon study, published in the International Journal of Sports Medicine and the multi-stage ultra-marathon study, published in Exercise Immunology Reviews,
and include medical diagnostics and fluorescence spectroscopy as well as UV curing and disinfection. A further application field is plant lighting, for
enabling in-situ measurements in various security and health relevant fields including biology, medicine, food control, and pharmacy.
Dr. Samuel Asfaha, a clinician-scientist at Lawson and an assistant professor of medicine at the Schulich School of medicine & Dentistry, Western University,
"says Labrique, Phd, an associate professor in the Bloomberg School's departments of international health and epidemiology."
and will lead to new candidates for biological and medical applications, and new production routes for enzymes of industrial use."
and protective properties that make it well-suited for a range of biomedical and optoelectronic applications.
'Research shows there is a clear need for long-acting antimicrobial products used in fillings and cements for crowns, bridges and orthodontic braces
. a Mayo Clinic oncologist and lead author of the study.""We believe we have identified a mechanism that seizes the cancer's biological engine
The test and a potential treatment are based on an emerging discipline of medical research called epigenomics, the complex biological process through
Vasquez is the James T. Delucio Regents Professor in the Division of Pharmacology and Toxicology at The University of Texas at Austin.'
Dr. Vasquez'studies on the role of non-B DNA sequences in these mechanisms can contribute to our knowledge of the etiology of human cancer.'
''With TACC's support, we were able to see that this is at least one plausible explanation in human cancer etiology,
Dr. Hesham Sadek, Assistant professor of Internal medicine and with the Hamon Center for Regenerative Science and Medicine.
"said Dr. Joseph Hill, Chief of the Division of Cardiology and Professor of Internal medicine at UT Southwestern,
The first study, published in the Annals of Surgery was carried out by an international team led by scientists at Imperial College London and clinicians at Imperial College Healthcare NHS Trust.
In collaboration with Pr Véronique Del Marmol (Department of Dermatology, Erasme Hospital, ULB) and the group of Pr François Fuks (Laboratory of cancer epigenetics, Faculty of medicine, ULB), Larsimont and colleagues demonstrated that
Study results appear online in Molecular Psychiatry. Huntington's disease is based a genetically, severe neurodegenerative disorder that results in progressive motor, cognitive and psychiatric impairment and, ultimately, death.
There is no effective treatment for Huntington's, which--like many neurodegenerative diseases--is characterized by an accumulation of misfolded mutant proteins that interfere with brain function.
As part of their study, the researchers introduced a new screening test that measures mutant huntingtin protein seeding in cerebrospinal fluid,
"Determining if a treatment modifies the course of a neurodegenerative disease like Huntington's or Alzheimer's may take years of clinical observation,
"said study leader Dr. Steven Potkin, UCI professor of psychiatry & human behavior.""This assay that reflects a pathological process can play a key role in more rapidly developing an effective treatment.
Additionally, gauging the seeding property of misfolded proteins may prove to be useful in the development of new treatments for other neurodegenerative diseases, such as Alzheimer's, ALS and Parkinson's.
UCI is a leading center for research on Huntington's disease and other related neurodegenerative disorders. Its scientists have helped identify mechanisms underlying HD
They are being published online in Ophthalmology, the journal of the American Academy of Ophthalmology. Retinitis pigmentosa is an incurable disease that affects about 1 in 4
-or surgery-related serious adverse events. After three years, there were no device failures. Throughout the three years, 11 subjects experienced serious adverse events, most
or chemical environment to provide unique functionality in a wide range of applications from energy to medicine.
or proteins that could be targeted by drugs, eventually leading to new medicines to fight cancer r
Indigo-Clean#was unveiled just before the annual meeting of theassociation for Professionals in Infection Control and Epidemiology (APIC) in Nashville."
In a study published in the journal Nature Medicine, the researchers reported that the tumor-suppressing protein AIM2,
This could be useful for medical servers, government data communications, financial markets and military communication channels, as well as quantum cloud communications and distributed quantum computing."
In addition, PLA is biocompatible and thus suitable for medical use, for instance in absorbable suture threads.
The researchers at the Medical Research Council's (MRC) Toxicology Unit based at the University of Leicester
and the London School of Hygiene & Tropical Medicine identified a key protein, called a protein kinase,
Co-lead author of the study Professor Andrew Tobin from the MRC Toxicology Unit which is located at the University of Leicester,
& Tropical Medicine, said:""It is a great advantage in drug discovery research if you know the identity of the molecular target of a particular drug and the consequences of blocking its function.
Professor Patrick Maxwell, chair of the MRC's Molecular and Cellular Medicine Board, said:""Tackling malaria is a global challenge,
This can lead to a wide-range of side-effects from renal failure to neurotoxicity, ototoxicity, nausea and vomiting.""
"Arrayfollowing the successful test results the researchers have been awarded a Wellcome Trust Pathfinder grant to begin preclinical development of organo-osmium compounds s
what causes neuropathic pain said John Imig, professor of pharmacology and toxicology at the Medical College of Wisconsin,
"says Dr. Kim who is also Professor of Surgery at Case Western Reserve University School of medicine and the Charles Hubay Chair at UH Case Medical center."
and assistant professor of Obstetrics and Gynecology, and Physiology and Pharmacology, in the OHSU School of medicine.""A failed IVF attempt takes an emotional toll on a woman who is anticipating a pregnancy as well as a financial toll on families, with a single IVF treatment costing thousands and thousands of dollars per cycle.
Their work, published online July 8 by the journal Science Translational Medicine, could pave the way for gene therapy in people with hearing loss caused by genetic mutations."
precision medicine treatment injected into their ears to restore hearing, "Holt says. Sound transducers: How TMC works Holt's team showed in 2013 that TMC1
associate professor and senior Cancer Research UK Fellow at the division of biomedical cell biology at Warwick Medical school.
#Gene therapy advance thwarts brain cancer in rats Researchers funded by the National Institute of Biomedical Imaging
The collaborators include colleagues from the Johns hopkins university School of medicine Departments of Neurosurgery, Oncology, Ophthalmology, and Pathology,
"In the future, the investigators envision that doctors would administer this therapy during the surgery commonly used to treat glioma in humans.
"says Karen Knudsen, Ph d.,Director of the Sidney Kimmel Cancer Center at Thomas Jefferson University, the Hilary Koprowski Professor and Chair of Cancer Biology, Professor of Urology, Radiation Oncology,
and Medical Oncology at Jefferson. Metastasis is thought of as the last stage of cancer. The tumor undergoes a number of changes to its DNA--mutations--that make the cells more mobile
As a result, patients often suffer for months before finding a medicine that makes them feel better.
who is also the vice president for Medical Affairs, University of Maryland, and the John Z. and Akiko K. Bowers Distinguished Professor and Dean of the School of medicine."
and developed,"says Josep Tabernero, Head of the Medical Oncology Department of Hospital Universitario Vall d'Hebron, Director of VHIO,
and is rapidly gaining importance and momentum in the oncology field. Liquid biopsy, also known as a blood-based biomarker test, is a fast, simple method for detecting RAS (KRAS and NAS) mutation status in tumors
It represents one more important step in realizing the true promise of precision medicine in oncology--the main focus behind research at VHIO which aims to both advance
However, recent data from the research group led by Markus Hengstschläger of the Institute for Medical Genetics of the Medical University of Vienna now suggest that another protein complex,
builds on his group's earlier sucess using a similar strategy to mark tumors for both diagnosis and precise surgical removal.
Callmann holds a fellowship through the Cancer Researchers in Nanotechnology Program at UC San diego. The National Institute of Biomedical Imaging
The Journal of the American Medical Association, is the first to follow patients taking patiromer for more than a few weeks.
a huge deal,"said George Bakris, MD, professor of medicine and director of the Comprehensive Hypertension Center at the University of Chicago Medicine."
The findings"have the potential to fundamentally change the current treatment approach to hyperkalemia,"according to an accompanying editorial by nephrologist Wolfgang Winklemayer, MD, Scd, of Baylor College of Medicine.
and funded by the University of Leeds and Netscientific plc, a biomedical and healthcare technology group specialisingin commercialising transformative technologies from leading universities and research institutes.
"The results of a pilot clinical study, carried out at the Leeds Institute of Cardiovascular and Metabolic Medicine under the supervision of Professor Peter Grant,
Professor Grant, Professor of Medicine at the University of Leeds and Consultant diabetes specialist, said:"
The study, published online and expected to come out this fall in a print edition of the journal Molecular Psychiatry,
"said Dr. Tom Mosley, director of the Memory Impairment and Neurodegenerative Dementia (MIND) Center at UMMC and senior scientist on the study."
"The effort was conducted through the Cohorts for Heart and Aging research in Genomic Epidemiology (CHARGE) consortium, in
"said Dr. Carla Ibrahim-Verbaas, a resident in neurology at Erasmus University Medical center in Rotterdam, The netherlands,
#Nanoparticles used to prevent inflammatory acne through slow-released nitric oxide GW researcher and dermatologist, Adam Friedman, M d,
This research, published in the Journal of Investigative Dermatology, identified that the nanoparticles were effective at killing Proprionobacterium acnes,
associate professor of dermatology at the GW School of medicine and Health Sciences and co-author of the study."
Friedman and his research team at the Albert Einstein College of Medicine and University of California Los angeles explored the mechanisms by
one of the most common dermatologic diseases affecting between 40-50 million people each year. Acne develops due to an inappropriate immune system response to various factors,
The finding means metal foams hold promise for use in nuclear safety, space exploration and medical technology applications."
This is the result of a ground-breaking new technique developed by a group of researchers from the Faculty of health and Medical sciences at the University of Copenhagen.
which are preclinical model organisms, we can link IL-6/Stat3 signalling to ARF, an important gene for cell cycle control and decisions to grow or to arrest.
"says Dr. Markus Selzner, a transplant surgeon in the Multi-Organ transplant Program at TGH, co-investigator of the clinical trial and the transplant surgeon who performed the donor operation.
Dr. Selzner is also a clinician-scientist at the Toronto General Research Institute who modified the Steen preservation solution used in the device at TGH
"says Dr. David Grant, Surgical Director of the Multi-Organ transplant Program, co-investigator of the clinical trial who also transplanted the donor liver,
chair of the Canadian Pediatric & Perinatal AIDS Research Group (CPARG) which runs the CPHSP.
#Long-sought discovery fills in missing details of cell'switchboard'A biomedical breakthrough, published in the journal Nature, reveals never-before-seen details of the human body's cellular switchboard that regulates sensory and hormonal responses.
so it can be used in biomedical applications. For their experiments, the researchers used thin films of gold that were 120 nanometers thick,
"which means it is not responsive to the common medical therapeutics. BLBC is more likely to metastasize
"explained corresponding author Sam Thiagalingam, Phd, associate professor of genetics & genomics, medicine and pathology & laboratory medicine at BUSM.
The vote paves the way for a medical world first for Britain, but one that is fiercely disputed by some religious groups and other critics.
namely how the immune system contributes to neurological and psychiatric disease. t early to speculate, says Kipnis,
A similar scenario may be at work in other neurological conditions; that too much or too little drainage from the central nervous system to the immune system might contribute to brain disease.
genetic manipulation and surgery are therapeutic approaches worth pursuing. Dr. Josep Dalmau, a neurology professor at the University of Pennsylvania not involved with the new study, agrees that the new findings could help to explain the initiation, maintenance,
and perhaps worsening of autoimmune disorders that affect the brain; and also that in light of the new findings the textbooks might need some revising t has become increasingly clear that the central nervous system is immune different rather than immune privileged,
and numerous mental and neurologic illnesses are known or thought to have an immune component. However that Kipnisgroup identified a tangible,
and all require invasive surgery. A new approach aims to change all that by swapping out flat implants with an injectable electronic mesh.
Fove could be used as a medical HMD where surgeons use it for detailed camera work
#Breast cancer victims die due to lack of radiologists in India. This startup offers an answer In 2012,145,
is too inefficient to solve the problem because of the country lack of radiologists. To combat that, Mumbai-based UE Lifesciences has invented a low-cost and portable breast screening device for early-stage detection of breast cancer.
#Canadian Space Robotics Technology to Help Sick Children Not much rivals the dexterity of a good surgeon hands.
The third prototype of Kidsarm, the first image-guided robotic surgical arm in the world specifically designed for pediatric surgery,
and researchers are hoping that the technology might soon lend a helping hand to surgeons around the country.
the robot is also promising for fetal, cardiac, neurological and urological surgeries. Using a pair of hand controllers in conjunction with high-precision, real-time imaging technology,
surgeons can pinpoint the area of concern to make it easier to reconnect delicate vessels, for example.
It is capable of working 10 times faster and with more accuracy than a surgeon hands when performing intricate procedures.
so that surgeons can compensate for the tissue motion that sometimes makes these surgeries difficult. A stereo camera generates a 3d point cloud,
This allows the surgeon to automate the suturing of small vessels and other microsurgical tasks.
Thanks to this technology, Kidsarm is capable of performing intricate procedures such as the suturing of blood vessels and tissues 10 times faster and with more accuracy than a surgeon hands.
and patterns are features of a number of neuropsychiatric disorders, including autism and schizophrenia. With these new findings, e now have an opportunity to investigate how gene mutations that cause
#3d printed Heart Model Makes Surgery Safer and Less Dangerous Three-dimensional printing technology has just found yet another use, this time it heart surgery.
When planning for an invasive procedure, surgeons are limited often to two-dimensional MRI and CT (computerized tomography) images,
which can lead them to form a widely inaccurate view of their patient physiology. Although three-dimensional images are also now available,
and complex surgery, currently performed at only a handful of pediatric hospitals in the US.
Studying the heart model allowed Kim to accurately plan the procedure thereby increasing safety and making follow-up surgery unnecessary. nstead of opening the chest
and making a decision about how to proceed, I could immediately begin fixing the problem,
me to plan the surgery in advance, which meant Esther spent less time in surgery and received less anesthesia,
making the procedure safer. Frank Ing, MD, Chief of Cardiology and co-director of the Heart Institute at CHLA, thinks that
since only a small number of 3d models have been used for heart surgery, the jury is still out
whether they actually improve surgical outcomes, but added that? our experience suggest that using models saves time in the OR,
which means increased safety and decreased costs. The use of 3d models is also likely to translate into a need for fewer surgeries
and allow children to spend less time recuperating in intensive care. Thanks to this innovative technique, Esther made a speedy recovery
and is expected to live a life free of medical complications. Otherwise she would have required multiple surgeries during the first years of her life.
In addition to surgical planning, 3d printing has also been used for other medical applications according to a recent article on Med Device Online
oncologists were able to use a 3d printed model that mimics the density of organs in a patient body,
which allowed to more accurately determine an appropriate dose of radiation. As 3d printing becomes cheaper,
medical professionals are hoping to include 3d printers into their regular toolset i
#New high-speed 3-D microscope gives deeper view of living things Opening new doors for biomedical and neuroscience research, Elizabeth Hillman,
associate professor of biomedical engineering at Columbia Engineering and of radiology at Columbia University Medical center (CUMC), has developed a new microscope that can image living things in 3d at very high speeds.
In doing so, she has overcome some of the major hurdles faced by existing technologies, delivering 10 to 100 times faster 3d imaging speeds than laser scanning confocal, two-photon,
2015. he ability to perform real-time 3d imaging at cellular resolution in behaving organisms is a new frontier for biomedical
The emergence of fluorescent proteins and transgenic techniques over the past 20 years has transformed biomedical research,
and Kimara Targoff (assistant professor of pediatrics, Department of Pediatrics), all of whom are starting to use the SCAPE system in their research. eciphering the functions of brain
lithography holography and biomedical imaging. Based on a chaotic cavity laser the technology combines the brightness of traditional lasers with the lower image corruption of light emitting diodes (LEDS.
and biomedical engineering and diagnostic radiology. his chaotic cavity laser is a great example of basic research ultimately leading to a potentially important invention for the social goodsaid co-author A. Douglas Stone the Carl A. Morse Professor
%while our laser has the speckle contrast of 3%.So our new laser has eliminated completely the issue of coherent artifact for full-field imaging. o-author Michael A. Choma assistant professor of diagnostic radiology pediatrics
and Gregory Kato of the Department of Medicine at the University of Pittsburgh. People with sickle cell disease an inherited genetic disorder have a variant form of hemoglobin that causes their red blood cells to take on a characteristic sickle shape when in low-oxygen conditions.
Hidde Ploegh an MIT professor of biology and member of the Whitehead Institute for Biomedical Research is also a senior author of the paper.
Clenbuterol does not harm muscle tissue in rodents at those doses showing the lab-grown muscle was giving a truly human response. ne of our goals is to use this method to provide personalized medicine to patientssaid Bursac. e can take a biopsy from each patient grow many
professor of biomedical engineering medicine and nursing at Duke university. The research was supported by NIH Grants R01ar055226 and R01ar065873 from the National Institute of Arthritis and Musculoskeletal and Skin disease and UH2TR000505 from the NIH Common Fund for the Microphysiological Systems Initiative.
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