people who were undergoing brain surgery and volunteered to get electrode implants saw improvement in their scores on memory tests,
and others who today suffer from intractable neurological problems, he said u
#British Scientists Want Permission To Genetically Edit Viable Human Embryos Cas9, the enzyme used in the CRISPR/Cas9 genome-editing technique, employed on a stand of DNA.
and monitor various medical conditions that may alter blood flow w
#Open-source Soil Sensors: Vinduino As California fourth straight year of drought forces farmers to cut back on water use,
The area in which Park has established herself as an expert is the field of study related to the creation and monitoring of delivery vehicles that carry medicine to specific locations within the body.
In doing this, the medical treatment would be more effective and the patient could remain stronger during treatment.
or risk to doctors who are trying to reach that locale with medicine. Two areas that have been of particular interest to her are spinal discs and places within the eyeball, both
Preliminary testing of the drug delivery procedure is being performed at the Laboratory Animal Medical Services (LAMS) facility on UC's East Campus. Currently Park is in the preclinical phase,
new ways to deliver medicines and other applications. Most commercial robots are made stiff of hard plastics and metal parts.
The multi-institutional group includes researchers from Baylor College of Medicine Rice Univ.,Stanford Univ. and the Broad Institute.
Rao likened the result to a new form of genome surgery: a procedure that can modify how a genome is folded by design
Her research today involves translating molecular imaging research to point-of-care diagnosticsescribes the fluorescence microscope system this week in a paper published in Biomedical Optics Express, from The Optical Society.
or MEG, is a noninvasive technique for investigating human brain activity for surgical planning or research,
Nanotechnology, Biology and Medicine. While current HIV treatments involve pills that are taken daily, the new regimens'long-lasting effects suggest that HIV treatment could be administered perhaps once or twice per year.
The hydrogel may be most useful for surgeries particularly for patients who take anticoagulant drugs to thin their blood. t interesting that you can take something so deadly
This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem
The substance used for medicine is produced by genetically modified bacteria and then purified, avoiding the risk of other contaminant toxins.
What we did was combine it with the hydrogel wee been working on for a long time. e think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in
Now, a team of researchers from Duke university have shown that these gene-controlling methods are capable of the high degree of precision required for basic science and medical research.
and potentially treating human diseases such as cancer, cardiovascular disease, neurodegenerative conditions and diabetes, which can be driven by mutations in control regions of the genome.
Crawford, associate professor of pediatrics, has spent more than a decade developing techniques to identify control regions across the genome
a team of bioengineers at Rice Univ. and surgeons at the Univ. of Pennsylvania have created an implant with an intricate network of blood vessels that points toward a future of growing replacement tissues and organs for transplantation.
or weeks to grow in the lab prior to surgery. The new study was performed by a research team led by Jordan Miller, assistant professor of bioengineering at Rice,
and Pavan Atluri, assistant professor of surgery at Penn. The study showed that blood flowed normally through test constructs that were connected surgically to native blood vessels.
In this study, we are taking the first step toward applying an analogy from transplant surgery to 3-D printed constructs we make in the lab. iller
and his team thought long-term about what the needs would be for transplantation of large tissues made in the laboratory. hat a surgeon needs
in order to do transplant surgery isn just a mass of cells; the surgeon needs a vessel inlet
and an outlet that can be connected directly to arteries and veins, he said. Bioengineering graduate student Samantha Paulsen and research technician Anderson Ta worked together to develop a proof-of-concept construct small silicone gel about the size of a small candy gummy bearsing 3
but they have some of the key features relevant for a transplant surgeon, Miller said. e created a construct that has one inlet and one outlet,
which are about 600 to 800 um. ollaborating surgeons at Penn in Atluri group connected the inlet
and unobstructed for up to three hours. his study provides a first step toward developing a transplant model for tissue engineering where the surgeon can directly connect arteries to an engineered tissue,
"said Barbara Sahakian from the department of psychiatry at Cambridge university.""This proof-of-concept study...
In the healthcare industry, these printers are used by dentists to create replicas of jaws and teeth as well as some finished dental implants and orthopedic surgeons have tested them to make customized hip replacements.
British scientists have used also 3d printing to create personalized replica models of cancerous parts of the body to allow doctors to target tumors more precisely y
The stickers are attached to the body using a medical-grade adhesive that can be peeled easily off after use without hurting the skin.
#This special chair is saving the lives of hundreds of dogs This might be the most regal solution for a medical problem wee ever seen:
ultimately, use a precision medicine-based approach to develop a therapeutic approach. Our study demonstrates that genetic screening alone is not enough."
Dr Rajat S. Barua, the corresponding author of the paper and a cardiologist, said:""With such widespread and ever increasing use of TRT,
. UCSD Professor of Pediatrics and Pharmacy. he consequences of this event on human health are still being felt three decades later.
and John Buchanan, UCSD Assistant Research Scientist in Pediatrics
#Spontaneous Rare Mutations Cause Half Of Autism Researchers are saying a new analysis of data on the genetics of autism spectrum disorder disputes a commonly held belief that autism results from the chance combinations
and Dr. Kenny Ye, a statistician at Albert Einstein College of Medicine. They predicted that unaffected mothers are"carriers"of devastating mutations that are transmitted preferentially to children affected with severe ASD.
as well as in neurological changes. Bogyo's group has extensive expertise in studying the activity of proteases, proteins capable of slicing up other proteins.
Preclinical testing provided evidence that ebselen is safe and tolerable, and it has shown no significant adverse effects in ensuing clinical trials.
#Hand And Arm Movement To Quadriplegic Patients Restored A pioneering surgical technique has restored some hand
however, instead of trains on a track, the surgeons redirect peripheral nerves in a quadriplegic's arms and hands by connecting healthy nerves to the injured nerves.
The researchers assessed outcomes of nerve-transfer surgery in nine quadriplegic patients with spinal cord injuries in the neck.
"Physically, nerve-transfer surgery provides incremental improvements in hand and arm function. However, psychologically, these small steps are huge for a patient's quality of life,
assistant professor of plastic and reconstructive surgery at at Washington University School of medicine in St louis."One of my patients told me he was able to pick up a noodle off his chest
'Before the surgery, he couldn't move his fingers. It meant a lot for him to clean off that noodle without anyone helping him."
Ultimately, medical professionals hope to discover a way to restore full movement to the estimated 250,000 people in the United states living with spinal cord injuries.
who performs surgeries at Barnes-Jewish Hospital?.""Patients often can't insert a catheter to empty their bladders
But after this surgery, one of my patients was able to independently catheterize himself, which he hadn't been able to do since his accident over a decade ago.
"Nerve-transfer surgery has been very successful in helping me because it restored triceps function and improvement in my grip,"said Bavlsik, an assistant professor of clinical medicine at the School of medicine."
"I am extremely grateful for this surgery.""Surgeons at Washington University pioneered nerve-transfer surgery.
Developed about 25 years ago by the study's senior author, Susan E. Mackinnon, MD, director of the Division of Plastic and Reconstructive Surgery at the School of medicine,
the technique initially was performed to restore movement in the extremities of patients who had injured peripheral nerves
and lost the ability to move a foot or an arm. But in the past five years, the same technique has been used to restore limited movement to patients with spinal cord injuries.
have traveled to St louis for the surgery. The operation can be performed even years after a spinal cord injury.
Since surgeons connect working nerves in the upper arms to a patient's damaged nerves in their arms and hands,
surgeons reroute healthy nerves sitting above the injury site, usually in the shoulders or elbows, to paralyzed nerves in the hand or arm.
"The gains after nerve-transfer surgery are said not instantaneous Mackinnon, director of the School of medicine's Center for Nerve Injury and Paralysis,
and the Sydney M. Shoenberg Jr. and Robert H. Shoenberg Professor of Surgery.""But once established, the surgery's benefits provide a way to let individuals with spinal cord injuries improve their daily lives."
"Another patient benefiting from the nerve-transfer technique is a 72-year-old right-handed man who had the surgery two years after he suffered a cervical spinal cord injury.
The doctors took healthy tissue from the patient's upper arm, connected it to a paralyzed nerve that controlled his ability to pinch
It has yielded so far important results that can accelerate the research of personalized healthcare and medicine.
"Professor Robert Huddart, Professor of Urological Cancer at The Institute of Cancer Research, London, and Consultant at The Royal Marsden NHS Foundation Trust, said,
"said project leader Mads Daugaard, an assistant professor of urologic science at UBC and a senior research scientist at the Vancouver Prostate Centre, part of the Vancouver Coastal Health Research Institute."
""This is an extraordinary finding that paves the way for targeting sugar molecules in pediatric and adulthood human cancer,
"said Poul Sorensen, a UBC professor of Pathology and Laboratory Medicine and distinguished scientist with the BC Cancer Agency and co-senior investigator on the study y
Dr. Albert J. Becker from the Institute of Neuropathology of the University of Bonn. The hippocampus, located in the temporal lobe, is a central switching station in the brain.
Becker, together with scientists from the departments of Experimental Epileptology and Neuroradiology of the University of Bonn Hospital as well as from the Hebrew University in Jerusalem (Israel
Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn. The researchers also see a possible potential in this new technology for novel diagnostic approaches in humans s
as they are attached to the skin with a bio-compatible, medical-grade adhesive. The current prototype,
and cannabidiol-another active compound that has shown promise as a medical treatment-told The New york times. Back in August, researchers from the University of California,
where medicinal compounds from marijuana would be welcomed if they didn come in the form of a plant that could be farmed illegally.
What yeast could also offer is the potential to more efficiently test the medicinal properties of specific active compounds in marijuana,
a professor of neuroscience and psychiatry at Icahn School of medicine at Mount sinai, told Tech Insider that using all the compounds in marijuana simultaneously is like"throwing 400 tablets in a cocktail
"Marijuana is embraced increasingly as medicine, yet there is limited evidence that it is effective against many of the conditions for
such as ejector pins for iphones, watch springs for expensive hand-wound watches, trial medical implants,
an assistant clinical professor of neurology. e hope that an implant could achieve an even greater level of prosthesis control
at Gothenburg Sahlgrenska University hospital, orthopaedic surgery has moved to a 6-hour day, as have doctors and nurses in two hospital departments in Umeå to the north,"The Guardian reports.
'and the focus of heavy investigation in a variety of neurodegenerative diseases,"said one of the researchers, Vijay K. Ramanan.
Chinese scientist Youyou Tu was awarded jointly the Nobel prize in Physiology or Medicine for her discovery of a new malaria therapy.
"We're in discussions with pharmaceutical companies to take this straight into humans after the appropriate preclinical toxicity studies,
when they try to seek out relevant medical information on the Internet. Unfortunately, as many of us are aware,
and medicine, bringing them better quality of life,""says Toledo Flores. The project was presented at the International Congress of Solar energy at Germany y
and physicians to propose a clinical trial using pluripotent stem cells treated with mitomycin C prior to transplant to treat Parkinson's patients and also other neurodegenerative conditions."
"said Dr. Inoel Rivera, a urologic oncologist at Florida Hospital Cancer Institute, which collaborated with Huo on the recent pilot studies."
The company manufacturers a test device specifically for medical research and diagnostic purposes s
#Engineers gain control of gene activity by synthetically creating key component of epigenome The new technology allows researchers to turn on specific gene promoters
"But many diseases, like cancer, cardiovascular disease or neurodegenerative conditions, have a much more complex genetic component.
The new device, called a biophotonic laser-assisted surgery tool, or BLAST, is a silicon chip with an array of micrometer-wide holes,
"said Dr. Michael Teitell, chief of the division of pediatric and developmental pathology, and a co-author of the paper.
Dr. Daniel Clemens, adjunct professor of medicine; Bai-Yu Lee, an assistant researcher; Ximiao Wen, a graduate student in mechanical engineering;
and Dr. Marcus Horwitz, professor of medicine and of microbiology, immunology and molecular genetics. The research was supported by a University of California Discovery Biotechnology Award, the National institutes of health, Nanocav and the National Science Foundation n
"This is the problem we're trying to overcome with precision medicine.""The scientist said the Hur-RNA binding site is like a long, narrow groove,
and involved the collaboration of chemists, cancer biologists, computer modeling experts, biochemists and biophysicists at KU--notably the labs of Xu, Jeffrey Aub in the Department of Medicinal Chemistry and Jon Tunge in the Department of chemistry.
"Trained as medical doctor and Ph d.,with both a grandfather and an uncle who died of cancer,
or likely genetic source, of each child's symptoms, according to a study published April 8 in the journal Molecular genetics & Genomic Medicine."
This is a prime example of the type of"personalized medicine"TGEN uses to zero in on diagnoses for patients,
Five of the six cases involved patients under the care of Dr. Saunder Bernes, a neurologist at Barrow neurological institute at Phoenix Children's Hospital.
requiring personalized medical treatment beginning with genetic diagnosis through sequencing like we perform at TGEN.""Dr. Hunter said."
She recently received a grant from the Pediatric Medical device Consortium at the Children's Hospital of Philadelphia to research this possibility i
For example, wearable/biomedical devices and electronic skins (e skins) should stretch to conform to arbitrarily curved surfaces and moving body parts such as joints, diaphragms, and tendons.
It can open avenues for power supplies in universal wearable and biomedical applications as well as self-powered ultra-stretchable electronics
accurate molecular diagnosis of tumors and other diseases to locations lacking the latest medical technology.
and an associate professor in the Division of Hematology-Oncology at the U-M Medical school.""Leukemia is a cancer of the body's blood-forming tissues,
The findings were published recently in the journal Gynecologic Oncology. Endometrial cancer of the uterus is the most common form of gynecologic cancer in Europe and North america.
The treatment primarily consists of removing the uterus and in some cases offering chemotherapy if the risk of recurrence is deemed high.
to identify patients in need of more extensive surgery.''Our results are promising, but more research is needed before ASRGL1 can be accepted as a new diagnostic tool in healthcare.
The novel knowledge is the result of longstanding research in the field of cell surface receptor proteins at the Department of Biomedicine at Aarhus University."
"says Associate professor Mette Madsen from the Department of Biomedicine at Aarhus University. With the new knowledge, the hope is that pathologists
and oncologists at an early stage will be able--unlike today--to predict whether a patient should expect spreading
which patients the most,"says Henrik Schmidt, consultant at the Department of Oncology at Aarhus University Hospital,
either medicine affecting the protein and its function thereby inhibiting the proliferation of the cancer cells and their survival,
Toxicology, and Biological engineering. Essigmann is cofounder of a pharmaceutical company that is developing mutagenic inhibitors of HIV."
"said study co-author Paul M Ridker, MD, MPH, the Eugene Braunwald Professor of Medicine at Harvard Medical school and director of the Center for Cardiovascular disease Prevention at Brigham and Women's Hospital."
Phd, research fellow and radiology resident at the UC San diego School of medicine and the study's first author.
a senior co-author and professor of biological psychiatry at the University of Oslo in Norway."
Complications from this disease can lead to emergency cesarean sections early in pregnancies to save the lives of the infants and mothers.
Professor Philip Ashton-Rickardt from the Section of Immunobiology in the Department of Medicine at Imperial, who led the study,
and have been published simultaneously in the New england Journal of Medicine.""Preclinical studies suggested that this combination therapy would have better outcomes than those elicited by their individual
or sequential administration,"said Hodi, who is also director of the Melanoma Center at the Dana-Farber Cancer Institute."
include high permeability polymers, nanomagnets for medical diagnostics applications, materials for the 3d printing of metal articles,
"The process can be expanded to biomedical sensor and solar-cell areas, "Ishihara said, "and will also realize stretchable--and even edible--electronics
As part of the precision medicine initiative at the Cancer Institute of New jersey, investigators--which include colleagues from Rutgers Robert Wood Johnson Medical school and RUCDR Infinite Biologics, the world's largest university-based biorepository,
standard of care laboratory testing for breast cancer,"says lead author Kim M. Hirshfield, MD, Phd, breast medical oncologist at the Cancer Institute and assistant professor of medicine at Rutgers
the opportunity exists to provide tailored therapies for patients,"notes Lorna Rodriguez, MD, Phd, director of the precision medicine initiative at the Cancer Institute and professor of obstetrics, gynecology and reproductive sciences
and associate professor of medicine and pharmacology at Robert Wood Johnson Medical school l
#Natural reparative capacity of teeth elucidated These results are published in the journal Stem Cells. The tooth is a mineralised organ, implanted in the mouth by a root.
the researchers from Inserm and Paris Descartes University at Unit 1124,"Toxicology, Pharmacology and Cellular Signaling,"have succeeded in extracting
"Currently, dentists use pulp capping materials (calcium hydroxide) and tricalcium phosphate-based biomaterials to repair the tooth and fill lesions.
The results reveal serious obstacles to using the method in medical applications. The scientists have tried to head off ethical concerns by using'nonviable'embryos,
which could prove useful in biomedical applications, among other uses
#Electrical power converter allows grid to easily accept power from renewable energy Doctoral student Joseph Carr developed the system with his adviser, Juan Balda, University Professor and head of the department of electrical engineering.
"Biomedical researchers can use these networks and the pathways that they uncover to understand drug action and side effects in the context of specific disease-relevant tissues,
"Our goal was to develop a resource that was accessible to biomedical researchers, "he says."
Other key collaborators on this study were Emanuela Ricciotti, Garret A. Fitzgerald and Tilo Grosser of the pharmacology department and the Institute for Translational Medicine and Therapeutics at the Perelman School of medicine, University of Pennsylvania;
"This is an exciting time in biomedical research, and I believe we are still at the early stages of developing new ways to think about biological networks and their control,
A few more preclinical trials are necessary before the artificial blood vessels can be used in humans. However, based on the results so far, the research team is very confident that the new method will prove itself for use in humans in a few years time e
A new report published in the Journal of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) describes the effectiveness of a new computer-based vision-screening test, the Jaeb Visual acuity Screener (JVAS),
"Broad adoption of this tool would result in a more standardized approach to pediatric vision screening in diverse medical
and community office settings,"commented lead investigator Tomohiko Yamada, OD, of the Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota."
or had undergone ocular surgery were included in the screening. The average screening time was 84 seconds, with a range of 23 to 357 seconds across all age groups.
could allow biomedical engineers to identify appropriate binding sites for drugs used to treat cancer and other diseases.
and effect might lie at the heart of some psychiatric disorders that involve delusional thinking, such as schizophrenia."
"said senior author Dr. David Lyden, the Stavros S. Niarchos Professor in Pediatric Cardiology and a professor of pediatrics in the Department of Pediatrics at Weill Cornell Medical College."
who also has appointments in the Sandra and Edward Meyer Cancer Center and the Gale and Ira Drukier Institute for Children's Health at Weill Cornell Medical College."
"said Vivian Ho, the chair in health economics at Rice's Baker Institute, a professor of economics at Rice and a professor of medicine at Baylor College of Medicine."
Our work also provides the preclinical framework supporting the development of new agents targeting NONO that could be used to sensitize cancer cells to a variety of drugs that cause DNA damage,
Director of the Sbarro Institute for Cancer Research and Molecular Medicine, at Temple University, Philadelphia a
#New test predicts sudden cardiac death in hemodialysis patients ICNC is organised by the Nuclear Cardiology
and Cardiac CT section of the European Association of Cardiovascular Imaging (EACVI), a registered branch of the European Society of Cardiology (ESC), the American Society of Nuclear Cardiology (ASNC),
#New test predicts sudden cardiac death in hemodialysis patients ICNC is organised by the Nuclear Cardiology
and Cardiac CT section of the European Association of Cardiovascular Imaging (EACVI), a registered branch of the European Society of Cardiology (ESC), the American Society of Nuclear Cardiology (ASNC),
The comparison involved the normal and tumor genomes from 43 children and adults with brain tumors, leukemia, melanoma and the pediatric eye tumor retinoblastoma."
"Using CONSERTING, researchers discovered genetic alterations driving pediatric leukemia, the pediatric brain tumor low-grade glioma, the adult brain tumor glioblastoma and retinoblastoma.
scientists can upload data for analysis. Work on CONSERTING began in 2010 shortly after the St jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project was launched.
The Pediatric Cancer Genome Project used next-generation, whole-genome sequencing to study some of the most aggressive and least understood childhood cancers.
whole-genome sequencing data for the Pediatric Cancer Genome Project. The project includes the normal and cancer genomes of 700 pediatric cancer patients with 21 different cancer subtypes.
CONSERTING combines a method of data analysis called regression tree, which is a machine learning algorithm, with next-generation,
"Traditional drugs--from cold medicine to chemotherapy--are composed of small molecules of a few dozen atoms, typically.
These packages of medicine will be ignored by the patient's immune system, which works against unknown proteins as well as many synthetic delivery vehicles s
As the spool pulls, the CNT ribbon is dragged between two surgical blades. While the blades appear straight to the naked eye,
and have been an area of recent and intense interest among oncologists. Since 2010, the FDA has approved vaccines and other immunotherapy drugs for melanoma, prostate cancer, and lung cancer.
a professor of medical pharmacology and physiology at the MU School of medicine and lead author of the study."
and Stephen I. Ryu, now a consulting professor of electrical engineering at Stanford and a neurosurgeon at the Palo alto Medical Foundation.
X-ray computer tomography (CT) has become an important diagnostic tool in medicine. Conventional CT SCANS are very detailed
"says Professor for Biomedical Physics Franz Pfeiffer of the Technical University of Munich in Germany, who led the new study published April 20 in the Proceedings of the National Academy of Sciences."
and dark-field CT in preclinical studies--an approach that could help visualize cancer.""We work closely together with two clinics to study tumors,
"Besides medical applications, multimodal tomography could also open up new possibilities in materials science, for instance, in studies of extremely durable and lightweight carbon fibers and other fibrous materials,
what scale,"explains Sophia Zackrisson and Kristina Lång, radiologists at Skåne University Hospital in Malmö and researchers at Lund University.
May 6, in the journal Science Translational Medicine.""This research is addressing neglected tropical diseases, "said Fletcher."
or other neurologic damage that can be severe or fatal. The standard method of screening for levels of Loa loa involves trained technicians manually counting the worms in a blood smear using conventional laboratory microscopes,
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