#Needle-sized mechanical wrist gives surgery a new angle Some of the most difficult types of surgery just got easier and more versatile.
Many larger surgical tools with flexible ends already exist, with designs that range from 2. 4 to 15 mm (0. 1 to 0. 6 in) in diameter,
While the mechanical wrist is expected to be useful in many different kinds of precise, small-scale surgery,
the researchers believe it will be particularly handy in needlescopic surgery (also known as micro-laparoscopy). This involves making incisions so tiny that they can be sealed with surgical tape and leave no scar behind.
Like laparoscopy, but on a smaller scale, it is accomplished using tiny surgical instruments that are fed through narrow tubes into the incision,
It's minimally-invasive surgery taken to the extreme. Armed with the flexible mechanical wrist, surgeons will soon be able to conduct operations on this scale through natural orifices such as the nose
and throat and through the sharp corners encountered in other areas such as the ankle and middle ear.
the researchers plan to test the wrist in transnasal surgery. This kind of surgery normally involves cutting a big hole in a patient's skull
or face so that tumors can be removed from the pituitary gland and skull base. It can also be done through the nasal cavity with an endoscope (a thin tube with a camera attached),
"We think once we give this tool to surgeons, they will find all kinds of applications we haven't thought of,
and the software interface that allows surgeons to control the mechanical wrist should be completed by the end of August.
which was used to print the word"contaminated"on surgical gloves. When the gloves were exposed to E coli bacteria,
however, the researchers found success without performing any invasive surgery. The new treatment uses a technique called transcutaneous electrical nerve stimulation
National Institute of Biomedical Imaging and Bioengineerin r
#Earth's magnetic field may be more than 750 million years older than previously thought The Earth's magnetic field is crucial to life on the planet.
and a Biotechnology and Biological sciences Research Council award, was published in the Science Translational Medicine journal in April.
and it Will be Not-for-Profit The world first malaria vaccine has been given approval by a European medical agency for future use in Sub-saharan africa, where more than a quarter million children under the age of five die every year from the disease.
With this approval from the European Medicines Agency Friday, the vaccine next will be considered by the World health organizations,
and emergency management officials protect those patients who rely on electricity-dependent medical equipment. The empower Map from HHS'Office of the Assistant Secretary for Preparedness
and Response is aimed at 1. 6 million Medicare fee-for-service beneficiaries whose medical and assistive equipment oxygen concentrators, ventilators,
and EMS teams prepare for surges in medical services. Emergency planners could also use the map to anticipate
"For people who rely on electricity-dependent medical equipment, prolonged power outages can mean life or death,"said Lurie."
because our ORS are set up to have dispensed individual kits to the anesthesiologist for each case,
This according to new peer-reviewed research published today in the journal Pediatric Critical Care Medicine.
The retrospective study of 16,239 Children's Hospital pediatric admissions between January 2006 and December 2013 compared the use of vital signs, a common indicator of patient condition, to that of Perahealth's Pediatric
mental state) to identify patients requiring urgent intervention with pediatric ICU transfer. The research, conducted by Children's Hospital clinicians,
"Many symptoms of serious pediatric conditions are also found in common conditions that do not require immediate intervention,
chief of pediatric critical care medicine at Children's Hospital of Pittsburgh of UPMC, said in a news release announcing the finding."
"Our research found the Pediatric Rothman Index to be a favorable electronic trigger for alerting clinicians to the need for rapid response teams,
#Spoken sentences can be reconstructed from brain activity patterns It is now possible to reconstruct spoken sentences from activity patterns of the human brain surface. rain to Textcombines knowledge from neuroscience, medicine and informatics.
our recent results indicate that both single units in terms of speech sounds as well as continuously spoken sentences can be recognized from brain activity. hese results were obtained by an interdisciplinary collaboration of researchers of informatics, neuroscience, and medicine.
An electrode array was placed on the surface of the cerebral cortex (electrocorticography (ECOG)) for their neurological treatment.
and this has got applications in chemistry, engineering, biology, medicine, so there's a lot of potential there and that's just for research purposes,
assistant professor of Materials science and engineering at the Mccormick School of engineering and Surgery at the Feinberg School of medicine, has developed a new kind of graphene ink that can be used to print large 3d structures.
once perfected, may open the door to a variety of new 3d printing applications within the art industry, medicine, aerospace, security, architecture, and more.
and make the surgery a lot more precise he said. There are other benefits over earlier efforts Kircher said.
The work appears in today's (Jan 21) issue of Science Translational Medicine e
#Bye bye Baubles: New 3d printers Could Build Implants Electronics Several new 3d printers showcased at CES 2015 in Las vegas earlier this month suggest that the 3d printing industry best known for churning out brightly colored plastic doodads could be turning over a new
Amid the rough-edged replicas of superheroes and army tanks that adorned the expo's 3d printing space stood a machine that prints tiny medical implants that dissolve inside the human body.
One company displayed a prototype of a 3d-printed medical device that can automatically stitch up patients after surgery.
"7 Cool Uses of 3d printing in Medicine During cartilage replacement surgery, the scaffold containing the stem cells would be implanted in the knee,
Dr. Daniel Kraft, a pediatrician and the founding executive director of Exponential Medicine, at a talk here at the 2015 CES."
said Dr. David Landers, a cardiologist and cofounder of the Edgewater, N. J.,company that makes the device.
"We feel that the findings have potential relevance to a wide range of microsystems technologies biomedical devices, optoelectronics, photovoltaics, 3d circuits, sensors and so on."
we can vary the location of magnetic stimulation to target the brain regions associated with other neurologic impairments, e g.,
This bodes well for neurorehabilitation programs in the future shedding light on the possibility that this technology might not be limited to stroke recovery alone a
so that chances can be made to their daily medicines or lifestyle. Is Grandma OK? Forget the cliché of dying alone and unnoticed till neighbors notice a funny smell.
The study was funded by the Howard Hughes Medical Institute, and appears today (June 4) in the journal Science n
#Shaping Implantable Medical devices to Avoid Immune system Tiny medical implants that can ferry drugs, cells, or other therapies safely to sites of disease are already seeing the light of day.
The hope is that this new application of optogenetics to voluntary muscles will help in medical research
allows the surgeon to see its location from the outside. This provides the ability to align the dissection line accurately along the light path
in a statement said Chris Barry, senior vice president and president of the Surgical Innovations business, Minimally Invasive Therapies Group at Medtronic. orking very closely with Dr. Trivedi, we were able to develop the Gastrisail system as a unique solution that promotes consistency of the sleeve,
Study in journal Restorative Neurology and Neuroscience: A new technique for modeling neuronal connectivity using human pluripotent stem cellsource:
has developed a surface sampling probe that may replace professional pathologists in identifying cancerous tissue during surgeries.
#Optical Probe to Help Remove Only Cancerous Tissues in Brain Surgeries Neurosurgeons removing a tumor have to be obsessive about resecting just enough
and MRI scans can make such surgeries last for many hours. Now researchers at Johns hopkins university are reporting on a new optical coherence tomography (OCT) probe that may provide surgeons real-time identification of cancerous tissues.
Previously the fact that tumors tend to be denser was the basis for many designed devices,
Here an example of the probe being used on brain tissue removed in actual surgeries: Study in Science Translational Medicine:
Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomographyource: Johns Hopkins Medicine
#Electromagnetic field Activated Drug Loadded Nanowires Drug releasing implants can be of great benefit for conditions requiring long term treatment in a targeted area of the body.
#Artificial Neurons That Work Like Real Ones to Treat Neurological Conditions, Paralysis Researchers at the Karolinska Institutet in Sweden have created reportedly an artificial neuron that apparently works just like our own living neurons
The big deal for clinical applications is that this technology may allow for chemical stimulation of neurological conditions triggered by naturally occurring biochemicals.
#New Technology for Blood-Free Glucose Sensing The University of Leeds may have solved one of the biggest holy grails in medicine,
In a small scale clinical study at the Leeds Institute of Cardiovascular and Metabolic Medicine, the technology has shown considerable promise to be able to match currently used glucometers.
and to be able to treat a variety of neurological conditions, researchers from Washington Universityin St louis and the University of Illinois at Urbana-Champaign have developed a wireless implant that can be controlled remotely to release drugs right into the brain.
Yet, in laboratory studies, the combination of the two factors can help identify which compounds are promising neurological drug candidates.
A 2014 Gallup poll found that 41 percent of Americans find medical testing on animals to be morally wrong,
or replacements during surgery and once they grab onto a nonliving surface they are notoriously difficult to treat
"said Michael R. Bruchas, Ph d.,associate professor of anesthesiology and neurobiology at Washington University School of medicine and a senior author of the study.
Both options require surgery that can damage parts of the brain and introduce experimental conditions that hinder animals'natural movements.
"Ultra-miniaturized devices like this have tremendous potential for science and medicine.""With a thickness of 80 micrometers and a width of 500 micrometers, the optofluidic implant is thinner than the metal tubes,
"said Dr. Michael Harrison, a professor of surgery at UCSF and a co-investigator of the study."
UCSF professor of surgery, is now heading up a clinical trial of this bandage. The project is funded through the Flexible Resorbable Organic and Nanomaterial Therapeutic Systems (FRONTS) program of the National Science Foundation.##
"said Charles Brendler, MD, Co-Director of the John and Carol Walter Center for Urological Health & Program for Personalized Cancer Care at Northshore and author of the study."
Dr. Hemant K. Roy professor of medicine and Chief of gastroenterology at Boston Medical center and an author of the study."
who are now exploring business opportunities for marketing the classification and determination of the degree of pluripotency of stem cells before their use in cell therapy or research in biomedicine.
thus having the capacity of becoming a standard method of quality control of stem or pluripotent cells before their use in cell therapy or research in biomedicine e
However, recent advances in biomedical technologies that enable researchers to capture single CTCS have renewed interest in CTC clusters,
. professor of surgery (biomedical engineering) at the Massachusetts General Hospital (MGH) and the Harvard-MIT Division of Health & Sciences Technology, report the development of a novel microfluidic chip that is specifically designed for the efficient capture of CTC clusters
which funds transformative technological innovation designed to solve major medical problems with a substantial disease burden,
A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.
"says co-senior study author Sofia D. Merajver, M d.,Ph d.,scientific director of the breast oncology program at the University of Michigan Comprehensive Cancer Center.
and even medicine. Now a team of Northwestern University researchers has found a way to print three-dimensional structures with graphene nanoflakes.
The fast and efficient method could open up new opportunities for using graphene printed scaffolds regenerative engineering and other electronic or medical applications.
assistant professor of materials science and engineering at Northwestern's Mccormick School of engineering and of surgery in the Feinberg School of medicine,
"Supported by a Google Gift and a Mccormick Research Catalyst Award, the research is described in the paper"Three-dimensional printing of high-content graphene scaffolds for electronic and biomedical applications,"published in the April
so it could be used for biodegradable sensors and medical implants. Shah said the biocompatible elastomer
Many thousands of times thinner than the average human hair, nanofibers are used by medical researchers to create advanced wound dressings--and for tissue regeneration
Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through"virtual biopsies
and fight tumor cells in the brain without resorting to surgery.""Our nanodrug can be engineered to carry a variety of drugs,
professor of neurosurgery and biomedical sciences at Cedars-Sinai and a lead author of an article published online in the American Chemical Society's journal ACS Nano.
Ljubimova, director of the Nanomedicine Research center in the Department of Neurosurgery and director of the Nanomedicine Program at the Samuel Oschin Comprehensive Cancer Institute, has received a $2. 5 million grant from the National institutes of health to continue the research.
"said Eggehard Holler, Phd, professor of neurosurgery and director of nanodrug synthesis at Cedars-Sinai.
MD, chair of the Department of Neurosurgery, director of the Maxine Dunitz Neurosurgical Institute, director of the Johnnie L. Cochran, Jr.,
Researchers from Cedars-Sinai's Department of Neurosurgery, Department of Biomedical sciences, Department of Imaging, and the Samuel Oschin Comprehensive Cancer Institute contributed to the study with colleagues from the University of Southern California and Arrogene Inc,
It can also be used in the production of artificial skin or other medical stuff. In this research, nanocomposite scaffold was made of silk fibroin,
Protamine is an important drug that is used as an anti-heparin agent to prevent blood coagulation during cardiovascular surgeries.
#Biomedical breakthrough: Carbon nanoparticles you can make at home Abstract: Researchers have found an easy way to produce carbon nanoparticles that are small enough to evade the body's immune system,
which could have broad medical applications, "Borgens said.""The technology is in the early stages of testing,
breaks through in medical technology June 23rd, 2015nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd,
or chemical environment to provide unique functionality in a wide range of applications from energy to medicine.
and medical industries due to their properties, including semi-conductivity, being piezoelectric and pyroelectric and biocompatibility.
and primarily funded by the Office of Science of the U s. Department of energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences,
and innovation programm 1 e. Its main objective is to reach a level of international excellence in nanomedicine characterisation for medical indications like cancer, diabetes, inflammatory diseases or infections,
EU-NCL is connected also closely to national medicine agencies and the European Medicines Agency to continuously adapt its analytical services to requests of regulators.
EU-NCL is designed, organized and operated according to the highest EU regulatory and quality standards. This project is important for Europe,
To provide a trans-disciplinary testing infrastructure covering a comprehensive set of preclinical characterisation assays (physical, chemical,
in-vitro and in vivo biological testing), allowing researchers to fully comprehend the biodistribution, metabolism, pharmacokinetics, safety profiles and immunological effects of their medicinal nanoproducts.
To foster the use and deployment of standard operating procedures (SOPS), benchmark materials and quality management for the preclinical characterisation of medicinal nanoproducts.
Joint Research Centre-European commission (IT) European Research Services Gmbh (DE), Leidos Biomedical Research, Inc. U s.)Trinity college Dublin (IE) Stiftelsen SINTEF (NO) University of Liverpool
Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology The postage stamp-sized square of fused silica Kjeld Janssen is holding
but inside the clear chip lies the potential to improve how medicine and medical research is done. f you can integrate
and automate an analysis technique into a chip, it opens doors to great applications, said Janssen, a postdoctoral researcher in the Sumita Pennathur Lab at UC Santa barbara. With only a minimal amount of human plasma,
particularly in remote areas where people don have access to a full medical lab, as well as data gathering for clinical trials or epidemiological studies.
For the impact his project will have in the field of translational medicine the postdoctoral scholar has been awarded the 2015 Lindros Award from the UCSB Translational Medical Research Laboratory (TMRL.
t very awesome, Janssen, a recent transplant from The netherlands, said of the award. It feels like a recognition of his effort,
and methodologies in all of medicine, said Dr. Scott Hammond, executive director of TMRL. orking with the Pennathur Lab, Kjeld Janssen research is intended to bring real-time detection to the world of medicine.
This technology, said Hammond, allows for the identification of specific DNA markers in an advanced microfluidic device. urther,
or medicine necessary to monitor or treat patients. Efforts to study and combat highly infectious diseases,
said UCSB mechanical engineering professor Sumita Pennathur. t a big step forward in terms of bringing out nanofluidic technology to real biomedical applications of disease diagnosis
such as in medical diagnostics for example. Their results are published now in Nature Communications. 3d structures in materials
so could feasibly be kept on the shelf of a doctors'surgery anywhere in the world.
builds on his group's earlier sucess using a similar strategy to mark tumors for both diagnosis and precise surgical removal.
Callmann holds a fellowship through the Cancer Researchers in Nanotechnology Program at UC San diego. The National Institute of Biomedical Imaging
according to Jonathan Schneck, M d.,Ph d.,a professor of pathology, medicine and oncology at the Johns hopkins university School of medicine's Institute for Cell Engineering."
the National Institute of General Medical sciences (grant number GM 07309), the National Cancer Institute (grant numbers CA 43460, CA 62924, CA 09243 and CA108835), the Troper Wojcicki
Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology July 7th, 201 0
They can also be used in medical and military industries. Ultrasonic bath has been used in the finishing process of the fabrics.
including medicine, electronics and energy. Discovered only 11 years ago, graphene is one of the strongest materials in the world, highly conductive, flexible, and transparent.
it is expected that an important step is taken in the development of nanotechnology in the field of medicine,
and power conditioning for defense, medical and commercial applications. But it has been challenging to find a single dielectric material able to maximize permittivity, breakdown strength, energy density and energy extraction efficiency.
A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.
"says co-senior study author Sofia D. Merajver, M d.,Ph d.,scientific director of the breast oncology program at the University of Michigan Comprehensive Cancer Center.
and even medicine. Now a team of Northwestern University researchers has found a way to print three-dimensional structures with graphene nanoflakes.
The fast and efficient method could open up new opportunities for using graphene printed scaffolds regenerative engineering and other electronic or medical applications.
assistant professor of materials science and engineering at Northwestern's Mccormick School of engineering and of surgery in the Feinberg School of medicine,
"Supported by a Google Gift and a Mccormick Research Catalyst Award, the research is described in the paper"Three-dimensional Printing Of high-Content Graphene Scaffolds for Electronic and Biomedical Applications","published in the April
so it could be used for biodegradable sensors and medical implants. Shah said the biocompatible elastomer
compact micro-actuators for aerospace, automobile, biomedical, space and robotics applications; and ultra-low thermal signature actuators for sonars and defense applications.
or replacements during surgery and once they grab onto a nonliving surface they are notoriously difficult to treat
Now, two groups of scientists are reporting for the first time that two new nucleotides can do the same thing--raising the possibility that entirely new proteins could be created for medical uses.
published in the journal Science Translational Medicine("Detection of pathological biomarkers in human clinical samples via amplifying genetic switches
New materials for energy application, new concepts for medical surfaces, new surface materials for tribological systems and nano safety and nano bio.
"explains Harald Ott, MD, of the MGH Department of Surgery and the Center for Regenerative medicine, senior author of the paper."
#Injectable nanoelectronics for treatment of neurodegenerative diseases It's a notion that might be pulled from the pages of science-fiction novel-electronic devices that can be injected directly into the brain,
and treat everything from neurodegenerative disorders to paralysis. It sounds unlikely, until you visit Charles Lieber's lab. A team of international researchers, led by Lieber, the Mark Hyman, Jr.
a process common to delivery of many species in biology and medicine-you could go to the doctor
"These type of things have never been done before, from both a fundamental neuroscience and medical perspective,
whose speed and precision make them useful for cataract and other eye surgeries. A femtosecond is one-quadrillionth,
and shortening the time to market of medicines in order to fully exploit them before patents run out.
Researchers then created a prototype BOC to assess the toxicological risk of new candidate compounds
representing a liver, tumour, heart muscle and neurological system, and they developed early prototypes with six and eight compartments that the project demonstrated could be extended to human cell cultures. arly-stage backing from the EU has helped really us develop a robust prototype
used in targeted surgeries, precision manufacturing and in the exploration of materials at the nanoscale.
"He said that makes it ideal for medical applications because the microrobotic tentacles can't damage tissues or even blood vessels.
More preclinical tests and subsequent clinical trials in humans will be required before the patch can be administered to patients,
or chemical environment to provide unique functionality in a wide range of applications from energy to medicine.
"says lead investigator Subroto Chatterjee, Ph d.,a professor of medicine and pediatrics at the Johns hopkins university School of medicine and a metabolism expert at its Heart and Vascular Institute."
#New device tracks chemical signals within cells Biomedical engineers at the University of Toronto have invented a new device that more quickly
or proteins that could be targeted by drugs, eventually leading to new medicines to fight cancer r
are being developed by mechanical engineers at Drexel University as a part of a surgical toolkit being assembled by the Daegu Gyeongbuk Institute of Science and Technology (DGIST) in South korea.
and very much in its infancy when it comes to medical applications, Kim said. project like this,
is an opportunity to push both medicine and microrobotics into a new and exciting place.
is being designed by Bradley Nelson from ETH Zurich, a pioneer in the field of microrobotic surgery.
stenting and angioplasty. Stenting is a way of creating a bypass for blood to flow around the block by inserting a series of tubes into the artery,
while angioplasty pushes out the blockage by expanding the artery with help from an inflatable probe. urrent treatments for chronic total occlusion are only about 60 percent successful,
In that study, published in a 2012 issue of Science Translational Medicine, microchips were implanted into seven elderly women,
said Robert L. Geahlen, Distinguished Professor of Medicinal Chemistry at Purdue. We were able to show the turn off of this kinase very rapidly alters the physical properties of the cell.
The phenomenon of RNAI is expected to find applications in medical treatments. RNAI is mediated by RNA-induced silencing complex (RISC),
Dr. Zhang and his Phd student Daniel Padmos examined gold and silver nanoparticles two very important materials, particularly in the future of biomedicine.
and these properties can be used in many different biomedical applications, explains Dr. Zhang, lead author of the study.
biomedical scientists have developed drugs with nanogold to target malignant tumours. The nanogold attracts light emitted from laser therapies
and designing the building blocks for groundbreaking discoveries in biomedical applications. This experience invigorates my interest in this type of research,
In the future, he plans to build upon this research to develop new functional nanomaterial systems and test their biomedical potential l
"The simple, low-cost and compact nature of this method makes it particularly attractive for point-of-care applications in settings that lack sophisticated medical resources.
central laboratories equipped with large and expensive analysis systems that are operated by experienced medical technicians.
The work opens the door for scientists to manipulate such organisms to produce compounds useful as fuels or medicines."
and observe and study the biological and medical significance of RNA misregulation. Details will be published the week of July 20 in the journal Proceedings of the National Academy of Sciences("Quantification
"Mirkin is the George B. Rathmann Professor of Chemistry in the Weinberg College of Arts and Sciences and professor of medicine, chemical and biological engineering, biomedical engineering and materials science and engineering.
from environmental remediation to medical analysis. The polymers are synthesized at room temperature, and don need to be prepared specially to target specific compounds;
offering the example of a cheap testing kit for urine analysis of medical patients. The study also suggests the broader potential for adapting nanoscale drug-delivery techniques developed for use in environmental remediation. hat we can apply some of the highly sophisticated,
and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
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