Despite the complicated physiology involved, NC State biomedical engineer Greg Sawicki and Temple University postdoctoral researcher Ben Robertson show that
Earlier research by Raichle, the Alan A. and Edith L. Wolff Distinguished Professor of Medicine, played a pivotal role in the discovery of brain regions now known as the efault mode network.
a biomedical engineer at the University of Oxford and lead author of the study. ot only is the number of subjects we get to study large,
The tomatoes themselves could potentially become the source of increased nutritional or medicinal benefit.""Our study provides a general tool for producing valuable phenylpropanoid compounds on an industrial scale in plants,
"said Martin."Our work will be of interest to different research areas including fundamental research on plants, plant/microbe engineering, medicinal plant natural products,
""Medicinal plants with high value are often difficult to grow and manage, and need very long cultivation times to produce the desired compounds.
Our research provides a fantastic platform to quickly produce these valuable medicinal compounds in tomatoes,
which are the major groups of medicinal compounds from plants
#Scientists Produce Tomatoes with Industrial Quantities of Natural Compounds Given the opportunity to drink fifty bottles of wine or eat one tomato,
The tomatoes themselves could potentially become the source of increased nutritional or medicinal benefit.""Our study provides a general tool for producing valuable phenylpropanoid compounds on an industrial scale in plants,
"said Martin."Our work will be of interest to different research areas including fundamental research on plants, plant/microbe engineering, medicinal plant natural products,
""Medicinal plants with high value are often difficult to grow and manage, and need very long cultivation times to produce the desired compounds.
Our research provides a fantastic platform to quickly produce these valuable medicinal compounds in tomatoes,
which are the major groups of medicinal compounds from plants
#Snake Venom-infused Hydrogel Stops Bleeding A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice university scientists.
The hydrogel may be most useful for surgeries particularly for patients who take anticoagulant drugs to thin their blood."
This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem
The substance used for medicine is produced by genetically modified bacteria and then purified, avoiding the risk of other contaminant toxins.
""We think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in
and Women Hospital in Boston and is now an assistant professor of medicine in the nephrology division at the University of Washington. nswering this question was important for understanding the potential of mini-kidneys for clinical kidney regeneration and drug discovery.
Biochemical engineer Christina Smolke and colleagues had been working on the problem of synthesizing opioids and other plant-based medicines in the lab for about a decade.
that it would require thousands of gallons of yeast to make a single dose of medicine."
would need to be addressed for engineered yeast to ever realize home-brew biosynthesis of medicinal opiates at meaningful yields."
In the lab of V. Reggie Edgerton, professor of integrative biology and physiology, neurobiology and neurosurgery, Pollock had attached electrical patches to the skin over his spinal cord.
this week to the world largest international society of biomedical engineers, said the electrical stimulation to the spinal cord appears to reawaken neurons there.
published this week by the IEEE Engineering in Medicine and Biology Society, is UCLA research scientist Parag Gad.
and Dr. Daniel Lu, associate professor of neurosurgery at UCLA David Geffen School of medicine. In a study published by the same team this summer in the Journal of Neurotrauma,
a pediatric oncologist at Fred Hutchinson and the senior author of the CIVO report, published today (April 22) in the journal Science Translational Medicine.
also published today in Science Translational Medicine. Unlike CIVO the cylinder is designed to be implanted into the tumor,
said Dr. David Milzman, a professor of emergency medicine at Georgetown University School of medicine.""Even more than food, you need clean water,
Still, several organizations are working to provide survivors with essential items and medical supplies. The Red cross says it has 19,000 relief kits,
And the World health organization has distributed medical supplies that can meet the needs of 40,000 people for three months,
a medical implant designed to change shape over time, that helped them keep breathing, researchers say."
"said Dr. Glenn Green, a pediatric otolaryngologist at the University of Michigan's C. S. Mott Children's Hospital and the senior author of a new report on the boys'cases.
a research fellow and resident surgeon at the University of Michigan Health System, told Live Science.
a biomedical engineer at the University of Michigan, told Live Science.""This is very important for quality and design control,
"This is the first time 3d printing has been used to create a medical implant for treating a life-threatening disease,
The scientists detailed their findings online today (April 29) in the journal Science Translational Medicine e
said Adriano Aguzzi, professor of neuropathology at the University of Zurich, who led the study.
"said study researcher Bruce M. Spiegelman, a professor of cell biology and medicine at Harvard Medical school.
Though it is surgeons'current best option, it still isn't that great. The surgery is invasive and destructive.
It can leave patients with a whole host of new issues, including the need for multiple surgeries.
Roger Ebert because doctors cut bone out of his hip and shoulder, suffered a limp for the rest of his life.
we might also adapt cells to groundbreaking new uses in other realms of medicine, or even entirely different fields, such as architecture, art and fashion.
"We conclude that MSA is a transmissible human neurodegenerative disease caused by alpha-synuclein prions,
when instruments used during brain surgery are cleaned without using certain methods. This is because traditional disinfection methods don't work to get rid of prions.
a polymath who wrote about literature, science, philosophy, religion, history and medicine, Clarke said.""The 13th-century manuscript may have been written by Bar Hebraeus himself,
challenges lie ahead in developing medicine for use in humans, she said.""The challenge with developing drugs that target ion channels"such as potassium channels is that these channels are found all over the body,
challenges lie ahead in developing medicine for use in humans, she said.""The challenge with developing drugs that target ion channels"such as potassium channels is that these channels are found all over the body,
a biochemist at the Baylor College of Medicine in Houston, said in a statement. To make sure that this supercoiled DNA actually shows up in the body,
or target the release of medicine locked in acoustically activated drug capsules, said study co-author Bruce Drinkwater,
But for the system to be useful for medical operations, the team would need to miniaturize it to manipulate objects on the micron scale.
#3d Printed Brain regions Help Neurosurgeons Prepare for Difficult Procedures While neurosurgeons have been able to virtually navigate volumetric images of patientsbrain structures gathered from CT and MRI scans,
difficult procedures within complex anatomy still remains challenging. At Boston Children Hospital, physicians are now using 3d-printed replicas of brain regions theyl be working on to practice with before actual surgery.
The researchers studying how the new capability may help in neurosurgery have focused on pediatric patients with cerebrovascular malformations requiring surgical or radiological intervention.
They used high resolution scans to recreate the patientsmalformed blood vessels and nearby anatomy using 3d printed resin.
They then used them to train on in preparation to the surgeries and also compared the models to the anatomy they were copied from,
%The study, published in the Journal of Investigative Dermatology, describes the use of ultrasonic waves to promote wound healing cells called fibroblasts to migrate into the wound through mechanical stimulation.
#Virtual Incision Robot Hopes to Lower Cost of Robotic Surgery (VIDEO) Thanks to Massdevice, we learned of a new company that developed a small surgical robot for performing laparoscopic procedures that may
It intended for surgeries that are performed often in an open fashion that can benefit from robotic laparoscopy, such as colon resections.
from learning how the brain works to treating previously unmanageable neurological conditions. So far, the triggering of neurons has been compared pretty dumb to how existing biofeedback devices and many electronic systems work.
and may set the stage for advanced neurological rehabilitation techniques. The so-called ptoclamptechnique involves continuous monitoring of the electrical activity of the neuronal cells excited via optogenetics
The technology, published in journal Science Translational Medicine, measures the level of circulating tumor DNA (ctdna),
In the study, GDNF alleviated neuroinflammation and reversed neurodegeneration in Parkinson disease model mice. One suggested mechanism of activity is that these cells,
#New Self-Positioning Transcatheter Mitral valve Developed by National University of Singapore Transcatheter heart valve replacements have become life savers for many frail patients who are unsuitable for open heart surgery.
"study co-author Dr. An Do, an assistant professor of neurology at the University of California, Irvine, said in a statement."
Dr. Elizabeth Tyler-Kabara, an associate professor of neurological surgery and bioengineering at the University of Pittsburgh, who was not involved with the study,
a biomedical engineer at the University of British columbia. t similar to when a grenade goes off
but hopefully it will lead to medical applications. This gives us new opportunities to look at cell structures
including medical diagnostics, industry, and the military. The research, published in the highly respected scientific journal, Nature Communications on September 1st, describes how the composition of gases in different environments can be detected by measuring small colour changes of the innovative bio-inspired sensor.
One of the most critical biological and medical tools available today, it lies at the core of genome analysis. Reading the exact make-up of genes,
each requiring preclinical and clinical testing with live subjects. How many chemical agents more to try? Moving at such rate, will we find the cure during our lifetime?
This approach will eventually provide more effective preclinical selection of drug candidates for the subsequent long-term and expensive clinical trial.
Owing to the above-mentioned merits, SPR biosensing is an outstanding platform to boost technological progress in the areas of medicine and biotechnology.
Widespread introduction of this method into preclinical trials will completely change the pharmaceutical industry. With SPR sensors we just need to estimate the interaction between the drug and targets on the sensing surface,
However, the developed chip should go through a clinical trial for medical applications
#Crucial hurdle overcome in quantum computing: quantum logic gate in silicon built for the first time A team of Australian engineers has built a quantum logic gate in silicon for the first time,
and development of new medicines by greatly accelerating the computer-aided design of pharmaceutical compounds (and minimising lengthy trial and error testing);
which is the basis for controlling electrons in computers, phones, medical equipment and other electronics.
The results of the study were published in the Journal of Medicinal Chemistry. Surgery, associated with cardiovascular diseases, such as ischemia,
often require the implantation of vascular grafts-artificial blood vessels, aimed at restoring the blood flow in a problematic part of the circulatory system.
which results in compulsory and lifelong intake of anticoagulants among patients and sometimes may even require an additional surgical intervention.
they actively release medicine into the blood. The lifetime of such grafts is determined often by the amount of drug stored within the graft,
The same approach may be used for kidney or liver surgery, but these are plans for the future,
Nanotechnology, Biology and Medicine, and after further research may offer a novel mechanism to address this aggressive and often fatal cancer that kills 14,000 women in the United states each year.
and chemotherapy that's often used as a follow-up to surgery. The new approach being developed by researchers from the OSU College of Pharmacy
"Surgery and chemotherapy are the traditional approaches to ovarian cancer, but it's very difficult to identify all of the places where a tumor has spread,
"Photodynamic therapy is a different approach that can be used as an adjunct to surgery right during the operation,
which a different compound called naphthalocyanine could be administered prior to surgery, causing the cancer cells to"glow
This provides a literal road map for surgeons to follow, showing which tissue is cancerous and
providing multiple mechanisms to improve surgical success and, with minimal side effects, help eradicate any remaining cancer cells that were removed not completely."
He also points to medical applications, such as physical feedback for athletes as they exercise and real-time hospital monitoring for caregivers concerned about changes in a patient's vital signs.
and wiring that normally are associated with close medical surveillance.""Overall, the military has the advantage of being able to move ahead with potentially higher risk research,
but hopefully it will lead to medical applications. This gives us new opportunities to look at cell structures,
such as ejector pins for iphones, watch springs for expensive hand-wound watches, trial medical implants,
#Targeted drug delivery with these nanoparticles can make medicines more effective: Nanoparticles wrapped inside human platelet membranes serve as new vehicles for targeted drug delivery The research,
and technology to achieve"precision medicine, "said Shu Chien, a professor of bioengineering and medicine, director of the Institute of Engineering in Medicine at UC San diego,
and a corresponding author on the study.""While this proof of principle study demonstrates specific delivery of therapeutic agents to treat cardiovascular disease and bacterial infections,
The collaborative effort also includes Kang Zhang, a professor of ophthalmology and chief of Ophthalmic Genetics at UC San diego and a corresponding author on this study y
That means the materials aren't durable enough for consumer electronics or biomedical devices.""Metallic materials often exhibit high cycle fatigue,
One of the most critical biological and medical tools available today, it lies at the core of genome analysis. Reading the exact make-up of genes,
which would enhance the effectiveness of medical interventions. The key breakthrough underlying this new technology came by chance."
including medicine, building, textile and military after being mass-produced. Among textile products, woolen fabrics are used in various industries due to their unique properties such as insulation and flexibility.
The next stage of the team's work involves working with medical researchers to test the new technology on animals.
the product can be used in orthopedic surgeries to recover and cure bones damaged due to tumors, cysts or fractures.
EPFL has developed a miniaturized microfluidic device that will allow medical staff to monitor in real time levels of glucose,
This advance will drastically reduce the number of machines cluttered around patients-an obvious practical advantage for the medical staff, not to mention the psychological boon for loved ones.
This progress towards more precise and effective medicine was achieved under the Nano-Tera initiative, which is financed by The swiss government.
EPFL has developed a miniaturized microfluidic device that will allow medical staff to monitor in real time levels of glucose,
This advance will drastically reduce the number of machines cluttered around patients-an obvious practical advantage for the medical staff, not to mention the psychological boon for loved ones.
This progress towards more precise and effective medicine was achieved under the Nano-Tera initiative, which is financed by The swiss government.
#Magnetic Nanosorbents Eliminate Fluoride from Water Researchers from Tehran University of Medical sciences used low-cost and available raw materials for the laboratorial production of nanosorbents with high efficiency in elimination of fluoride from contaminated water.
eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine and technology.
According to Burke, the highly customized approach that chemists have relied long on to synthesize small molecules is time consuming and inaccessible to most researchers. lot of great medicines have not been discovered yet because of this synthesis bottleneck,
Burke says. oing real atomistic modifications to transform nature's starting points into actual medicines is really,
He has founded a company, REVOLUTION Medicines, to use and continue to develop the technology for this purpose.
engineers, medical doctors, and even the public to produce small molecules. hen you put the power to manufacture into the hands of everyone,
"Mirkin is the George B. Rathmann Professor of Chemistry in the Weinberg College of Arts and Sciences and professor of medicine, chemical and biological engineering, biomedical engineering and materials science and engineering.
making them a versatile tool in medicine. The current study's results show, Mirkin said,
and creates previously unachievable geometries that open opportunities for innovation not only in health care and medicine,
dental implants or prosthetics to be printed 3d on-demand in a medical setting.""CLIP's debut coincides with the United Nation designating 2015 as the International Year of Light and Light-Based Technologies,
and defects, says a Texas A&m University biomedical engineer who is part of the team developing the biomaterial.
Its findings could change the way medical professionals treat fractured bones that experience difficulty in healing
a biodegradable gel used in several biomedical applications because of its compatibility with the body. When nanosilicates are incorporated into a gelatin matrix, several physical,
Based on our strong preliminary studies, we predict that these highly biofunctional particles have immense potential to be used in biomedical applications
or supercapacitors without an external power source and make new commercial and medical applications possible.
Small, lightweight devices could play life-changing roles as robotic skin or in other biomedical applications.
#Medical nanoparticles for the local treatment of lung cancer Nanoparticles can function as carriers for medicines to combat lung cancer:
scientists from the Helmholtz Zentrum Mnchen (HMGU) and the Ludwig-Maximilians-Universitt (LMU) in Munich have developed nanocarriers that site-selectively release medicines/drugs at the tumor site in human and mouse lungs.
in the effectiveness of current cancer medicines in lung tumour tissue. Tumor tissue in the lung.
Sabine van Rijt, CPC/ilbd, Helmholtz Zentrum Mnchen) Nanoparticles are extremely small particles that can be modified for a variety of uses in the medical field.
For example, nanoparticles can be engineered to be able to transport medicines specifically to the disease site while not interfering with healthy body parts.
and so the medicines stay protected in the nanocarrier.""Using these nanocarriers we can very selectively release a drug such as a chemotherapeutic agent specifically at the lung tumour,"reports research group leader Meiners."
At the same time, this approach also makes it possible to decrease the total dose of medicines and consequently to reduce undesirable effects."
New materials for energy application, new concepts for medical surfaces, new surface materials for tribological applications and nano safety and nano bio.
#Novel nanoparticle therapy promotes wound healing (w/video)( Nanowerk News) An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal
were published online in the Journal of Investigative Dermatology("Fidgetin-like 2: a novel microtubule-based regulator of wound healing".
including everyday cuts and burns, surgical incisions, and chronic skin ulcers, which are a particular problem in the elderly
Dr. Sharp and project co-leader Joshua Nosanchuk, M d.,professor of medicine at Einstein and attending physician, infectious diseases at Montefiore Medical center, developed a wound-healing therapy that uses
Dr. Sharp collaborated with Joel Friedman, M d.,Ph d.,professor of physiology & biophysics and of medicine at Einstein,
and study co-leader Adam Friedman, M d.,director of dermatologic research at Einstein and Montefiore, who together had developed nanoparticles that protect molecules such as sirna from being degraded as they ferry the molecules to their intended targets.
Phd, program director for Optical Imaging at the National Institute of Biomedical Imaging and Bioengineering."
This will open the door to new applications for thermal sensors in biomedical devices consumer products and low cost thermal cameras s
and possibly even neurodegenerative diseases.""Injuries to the central nervous system affect thousands of Canadians every year and can lead to lifelong disabilities.
said Hyun Koo, a professor in the Department of Orthodontics and co-senior author of the work.
onl prweb About PI PI is a leading manufacturer of precision motion control equipment, piezo motors, air bearing stages and hexapod parallel-kinematics for semiconductor applications, photonics, bio-nano-technology and medical engineering.
Even with surgical interventions or traditional treatments some of the cells the stem cells tend to survive
"displays the development of a powerful synthetic method that enables rapid access to para-functionalized benzene derivatives to construct libraries of bioactive compounds that are useful in medicinal chemistry.
In the medical field, the substance has shown activity against cancer cell lines. In cosmetics, people appreciate the good smell, in soft drinks a fine, subtle taste.
Johns Hopkins Medicine researchers may have discovered a way to prevent rejection by using biodegradable nanoparticles that release needed medication into the eye after surgery.
This discovery could solve the decades-old issue of medicine compliance and help patients achieve corneal transplant success. Medicine compliance is a major challenge in patient care,
says Walter Stark, M d.,chief of the Division of Cornea, Cataract and External Eye diseases at Johns Hopkins. About 60 to 80 percent of patients dont take medicine the way they are supposed to.
In an animal study being published in the March 10 issue of the Journal of Controlled Release("Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats),
"researchers looked into ways to alleviate the strain of adhering to a post-surgery treatment regimen that is sometimes hard to manage.
Rats that underwent a corneal graft surgery were divided randomly into four groups and were given various treatments.
biodegradable nanoparticle loaded with corticosteroids for timed release of medicine. The other three groups received weekly injections of saline, placebo nanoparticles and free dexamethasone sodium phosphate aqueous solution after surgery, respectively.
Treatments were given until the graft was deemed clinically as failed or until the nine-week test period concluded.
and did not leak within one week of the surgery. The concentration of the treatment also remained stronger than in the other three treatment groups Additionally,
Two weeks after surgery, rats that received the placebo nanoparticle and saline injections had severe swelling, opaque corneas and unwanted growth of new blood vessels, all indicating graft failure.
a research associate at the Center for Nanomedicine at the Wilmer Eye Institute at Johns Hopkins Medicine.
while making medicine adherence much easier on patients and their families The nanoparticle loaded with medication could eliminate the need for a patient to remember to take their medicine often multiple doses per hour after a surgery,
and medicine to look further into better ways to treat eye diseases s
#Flexible sensors turn skin into a touch-sensitive interaction space for mobile devices (w/video) If a mobile phone rings during a meeting,
as they are attached to the skin with a biocompatible, medical-grade adhesive. Users can therefore decide where they want to position the sensor patch
which designs and builds organisms able to make useful products such as medicines, energy, food, materials and chemicals.
which is the basis for controlling electrons in computers, phones, medical equipment and other electronics.
The results of the study were published in the Journal of Medicinal Chemistry("Synthesis of Thrombolytic Solel Coatings:
"Surgery, associated with cardiovascular diseases, such as ischemia, often require the implantation of vascular grafts-artificial blood vessels,
which results in compulsory and lifelong intake of anticoagulants among patients and sometimes may even require an additional surgical intervention.
they actively release medicine into the blood. The lifetime of such grafts is determined often by the amount of drug stored within the graft,
The same approach may be used for kidney or liver surgery, but these are plans for the future,
"said Neil Spector, an oncologist at Duke Medicine familiar with the work.""But it's not just the increase in clinical efficacy
and structural biology at UC Berkeley and investigator with the Howard Hughes Medical Institute, is a leading authority on the structure and dynamics of microtubules.
With Rodriguez new approach, existing robots in manufacturing, medicine, disaster response, and other gripper-based applications may interact with the environment,
A surgical robot may push a scalpel against an operating table to adjust its grip, while a forensic robot in the field may angle a piece of evidence against a nearby rock to better examine it. xploiting the environment is,
or surgery, or field operations, or even space exploration whenever you have a gripper that is not dexterous like a human hand,
and industrial R&d in a wide spectrum of applications, from transport to medicine. The Laser Applications Centre of AIMEN is devoted to applied research in the field of laser materials processing,
However, one challenge is reducing the tissue/neuron damage associated with needle penetration, particularly for chronic insert experiment and future medical applications.
I think this technology definitely has the potential to be transformative in medicine e
#Reflexes for robots (w/video)( Nanowerk News) Deep in the basement of MITS Building 3, a two-legged robot named HERMES is wreaking controlled havoc:
Now, Slater and a team of researchers from Duke university, Baylor College of Medicine and Rice university have developed an image-based,
which may someday extend the life of medical implants, fiber-optic cables and other hard to repair in place objects, according to an international team of researchers."
such as ejector pins for iphones, watch springs for expensive hand-wound watches, trial medical implants,
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