| Amnesia (8) |  |
| Anorexia (5) | |
| Anxiety (61) | |
| Ataxia (18) | |
| Autism (210) | |
| Delusional disorder (9) | |
| Dementia (87) | |
| Hallucination (11) | |
| Mania (51) | |
| Mental disorder (32) | |
| Multiple sclerosis (75) | |
| Paranoia (7) | |
| Phobia (5) | |
| Psychosis (9) | |
| Schizophrenia (137) | |
| Speech disorder (7) | |
| Stress (299) | |
and provides a new way to study both the normal brain and brain disorders such as epilepsy and autism.
and have been suggested as a possible cause of neurodevelopmental disorders such as autism, epilepsy or intellectual disability (see this review article for further background).
#Autism diagnosis catches up for kids in Tanzania Brown University rightoriginal Studyposted by David Orenstein-Brown on October 2 2014to diagnose autism in Tanzania researchers adapted several techniques
There is no autism diagnostic measure validated for use in Swahili a major language of the region.##
##Historically in Tanzania parents that have sought autism diagnoses had to go to other countries to receive those diagnoses##says Ashley Johnson Harrison a former postdoctoral fellow at Brown University who is now an assistant professor at University of Georgia. Researchers used the new
Using the diagnostic panel researchers were able to make diagnoses that consistently distinguished kids with autism spectrum disorder from those with other similar disorders.
because distinguishing between autism spectrum disorders and other conditions can ensure that children receive proper education
##Initially we only identified the most severe cases of autism##says Johnson Harrison who works under the mentorship of Eric Morrow in the department of psychiatry and human behavior at Brown.##
and Developmental Disabilities and was presented at a meeting of the International Meeting for Autism Research.
They used the Childhood Autism Rating Scale-Second Edition (CARS-2) to help rate child behavior because of the instrument s flexible usage guidelines.
or guardians information about autism and guidance on using behavioral strategies to improve child skills.
Of the children she tested 30 were diagnosed as having autism spectrum disorders and 11 as having other##global delay##conditions such as suspected intellectual disabilities Down syndrome or other disorders.
if her diagnostic assessment had produced reliable statistically significant differences between the autism and non-autism groups.
The average CARS-2 score for the autism group was 28 percent higher (at 37.75) than the average for the global delays group (at 27.15) a statistically significant difference.
In addition Tanzanian children diagnosed with autism scored in similar ranges on the CARS-2 as compared to children with autism in the United states. The autism group also had significantly more DSM-V autism symptoms than the global delays group suggesting that the assessment measures
were helpful in reliably eliciting the information needed to assess autism spectrum disorders. Johnson Harrison says she hopes that the assessment protocol
Many groups have begun to apply CLARITY to probe brains donated from people who had diseases like epilepsy or autism
#Living near pesticides in pregnancy ups autism risk University of California Davis rightoriginal Studyposted by Phyllis Brown-UC Davis on June 23 2014pregnant women living
in close proximity to chemical pesticide application had a two-thirds higher risk of having a child with autism spectrum disorder or other developmental delay according to a new study.
and carbamates applied during the study participants pregnancies and later diagnoses of autism and developmental delay in their offspring.
##This study validates the results of earlier research that has reported associations between having a child with autism
and may pose threats to brain development during gestation potentially resulting in developmental delay or autism.
and linking the data to the residential addresses of approximately 1000 participants in the Northern California-based Childhood Risk of Autism from Genetics and the Environment (CHARGE) Study.
The study includes families with children between two and five diagnosed with autism or developmental delay or with typical development.
whose children developed autism or had delayed cognitive or other skills.####The researchers found that during the study period approximately one-third of CHARGE Study participants lived in close proximityâ##within 1. 25 to 1. 75 kilometersâ##of commercial pesticide application sites.
Organophosphates applied over the course of pregnancy were associated with an elevated risk of autism spectrum disorder particularly for chlorpyrifos applications in the second trimester.
Pyrethroids were associated moderately with autism spectrum disorder immediately prior to conception and in the third trimester.
##Research from the CHARGE Study has emphasized the importance of maternal nutrition during pregnancy particularly the use of prenatal vitamins to reduce the risk of having a child with autism.
multiple scans performed over time could be used to monitor the progress of patients treated for brain injuries, developmental disorders such as autism,
Researchersinterests in these networks have grown enormously over the past decade as the networks have been tied to many different aspects of brain health and sickness, such as schizophrenia, autism and Alzheimer disease.
The National institutes of health, Autism Speaks, a Fulbright Science and Technology Phd Award, and a Mcdonnell Centre for Systems neuroscience grant funded the research s
#How an app might help screen kids for autism A new video analysis tool may help spot early signs of autism.
tracks and records infantsactivity during videotaped autism screening tests. Results show the program is as effective at spotting behavioral markers of autism as experts giving the test themselves,
and the software performs better than non-expert medical clinicians and students in training. ee not trying to replace the experts,
a graduate student in computer and electrical engineering at Duke university. ee trying to transfer the knowledge of the relatively few autism experts available into classrooms and homes across the country.
because research has shown that early intervention can greatly impact the severity of the symptoms common in autism spectrum disorders.
THREE TESTS The study focused on three behavioral tests that can help identify autism in very young children.
GENERAL PRACTITIONERS he great benefit of the video and software is for general practitioners who do not have trained the eye to look for subtle early warning signs of autism
says Amy Esler, an assistant professor of pediatrics and autism researcher at the University of Minnesota,
which will appear online in the journal Autism Research and Treatment. he software has the potential to automatically analyze a child eye gaze, walking patterns,
which connects researchers from disparate fields to experts in computer programming to help analyze large data sets. ee currently working with autism experts at Duke Medicine to determine what sorts of easy tests could be used on just a computer
The research has shown that the earlier autism can be spotted, the more beneficial intervention can be.
This discovery may have implications for understanding neural circuit dysfunctions that underlie autism in humans. Humans with autism often show a reduced frequency of social interactions
and an increased tendency to engage in repetitive solitary behaviors. Autism has also been linked to dysfunction of the amygdala a brain structure involved in processing emotions.
This discovery which is like a eesaw circuitwas led by postdoctoral scholar Weizhe Hong in the laboratory of David J. Anderson biology professor at Caltech and an investigator with the Howard Hughes Medical Institute.
and his colleagues say may have some relevance to human behavioral disorders such as autism. n autismanderson says here is a decrease in social interactions
and promoting these perseverative persistent behaviors. tudies from other laboratories have shown that disruptions in genes implicated in autism show a similar decrease in social interaction and increase in repetitive
but if you found the right population of neurons it might be possible to override the genetic component of a behavioral disorder like autism by just changing the activity of the circuits#tipping the balance of the seesaw in the other directionhe says.
which social information processing is disruptedâ##like autism spectrum disorderâ ##and may lead to new strategies for improving social cognition in several psychiatric disorders.
which is disrupted in disorders such as autism. Additionally this study is remarkable for its evolutionary aspect.
which was funded by grants from the US National institute of mental health and the Office of Research Infrastructure Programs as well as the Nancy Lurie Marks Family Foundation and National Alliance for Autism Research.
which the brain is excited too and autism in which the brain is excited not enough. f we can figure out how these set points are built we may be able to adjust them
##People with autism, who can have a hard time reading facial expressions, may be among the beneficiaries, Dr. Burleson said.
Facet's applications are incredibly far-reaching from treating children with autism to play-testing video games.
Recognizing other people's emotions based on their facial expressions is a challenge for many people who have an autism spectrum disorder particularly children.
As a research professor at the University of California San diego's Machine Perception Lab Bartlett has been studying the use of facial recognition software to help people with autism for several years. 5 Controversial Mental health Treatments
This game helps children with autism recognize other people's emotions through their facial expressions as well as teaches them how to make facial expressions that express their own feelings.
and when disorders like autism first take root researchers say. This is another installment in our suite of brain atlases to try to map how all genes are used across the brain
Allen Institute for Brain science) The map of a healthy developing brain also provides clues to the origin of developmental disorders such as autism the researchers said.
Other studies have revealed certain genes that are active in autism. Lein's team saw these genes were turned on in newly generated excitatory neurons
(which activate other neurons) in the prenatal cortex suggesting autism may start in the womb as opposed to later in life.
#Genetic Brain disorders Converge at the Synapse Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.
a treatment developed for one genetic cause of autism and intellectual disability might be useful for many others.
the Picower Professor of Neuroscience in MIT Picower Institute for Learning and Memory, showed that two very different genetic causes of autism
and autism is fragile X syndrome, which arises when a single gene on the X chromosome,
Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,
Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.
Studies at other institutions have identified mutations in the gene for Syngap associated with autism and intellectual disability.
#What Autism Can Teach Us About Brain Cancer Both disorders involve faults in the same protein.
Applying lessons learned from autism to brain cancer, researchers at The Johns hopkins university have discovered why elevated levels of the protein NHE9 add to the lethality of the most common and aggressive form of brain cancer, glioblastoma.
A summary of their work in human tumor cells and mice will be published on Feb 9 in the journal Nature Communications. y laboratory research on cargo transport inside the cells of patients with autism has led to a new strategy
Rao research group previously showed that autism-associated defects in the protein NHE9 are harmful
Based on their autism research, the team suspected that the boost NHE9 gave to glioblastomas was explained by abnormal endosome acidity.
Further studies revealed that, in contrast to autism, NHE9 is overactive in brain cancer, causing endosomes to leak too many protons
autism obesity acne and allergies. The co-directors are presenting their research collaboration this week at an MGH-hosted conference on microbes metabolism and mucosal circuits.
Still others could help children with autism better interact el Kaliouby says such as games that make people match facial cues with emotions.
Together they quickly started applying the facial-coding technology to autism research and training the algorithms by collecting vast stores of data.
and assembled the world s largest collection of DNA samples in psychiatric research currently more than 175000 samples including schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and healthy control samples.
Significant efforts are ramping up in bipolar disorder autism and other conditions. We are going to illuminate the biology behind these conditions says Eric Lander founding director and president of the Broad Institute and a professor of biology at MIT.
Complete the list of all genes that play roles in severe psychiatric disorders including schizophrenia bipolar disorder autism and others.
Stanley Center researchers focus on schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and other neuropsychiatric disorders.
2015 SHARE Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.
a treatment developed for one genetic cause of autism and intellectual disability might be useful for many others.
the Picower Professor of Neuroscience in MIT Picower Institute for Learning and Memory, showed that two very different genetic causes of autism
and autism is fragile X syndrome, which arises when a single gene on the X chromosome,
Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,
Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.
Zhang plans to use the techniques to study the genetics of autism and schizophrenia. He has begun already to insert genes linked to each disorder one by one into animal models to observe their effects.
Kidding aside an app like this could help people with conditions such as autism that makes it hard for them to read emotions.
Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia,
and autism, in a dish. With the addition of a blood circulation, which is currently lacking,
"It's a lot like autism, in that many different CNVS affecting different genes are involved which could possibly explain why the clinical presentations of both these conditions are noted so diverse
or new, CNVS identified in these patients with cerebral palsy is even more significant than some of the major CNV autism research from the last 10 years.
"It's a lot like autism, in that many different CNVS affecting different genes are involved which could possibly explain why the clinical presentations of both these conditions are noted so diverse
or new, CNVS identified in these patients with cerebral palsy is even more significant than some of the major CNV autism research from the last 10 years.
when mutated, can give rise to a number of mental health conditions including schizophrenia, bipolar disorder, major clinical depression and autism.
DISC1 mutations have also been linked to autism and Asperger syndrome, suggesting that the developmental effects of DISC1 could also be important for understanding these mental health conditions.
About one out of every hundred Norwegians develop schizophrenia or autism in the course of their lifetime.
Many psychiatric disorders such as autism, schizophrenia and bipolar disorder are characterised by poor social functioning. Oxytocin is a hormone that influences social behaviour
May yield new treatments The next step in the research is to carry out the same tests on people with mental illness. e are now running tests in volunteers diagnosed with autism spectrum disorders,
#Possible Biomarker for Autism Discovered Study also points to potential new drug discovery advances. By identifying a key signaling defect within a specific membrane structure in all cells, University of California,
they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.
Dr. J. Jay Gargus, Ian Parker and colleagues at the UCI Center for Autism Research & Translation examined skin biopsies of patients with three very different genetic types
and possibly digestive and immune problems associated with autism. e believe this finding will be another arrow in the quiver for early and accurate diagnoses of autism spectrum disorders,
said Gargus, director of the Center for Autism Research & Translation and professor of pediatrics and physiology & biophysics. qually exciting,
Autism spectrum disorder is a range of complex neurodevelopmental disorders affecting 2 percent of U s. children.
To see if IP3R function is altered across the autism spectrum, clinical researchers at The Center for Autism & Neurodevelopmental Disorders
which is affiliated with the Center for Autism Research & Translation are currently expanding the study
In the area of drug discovery, scientists at the Center for Autism Research & Translation continue to probe the IP3R channel,
The brains of people who have autism show signs of hyperexcitability, which is seen also in epilepsy,
Cells from individuals who have depressed autism exhibit levels of calcium signaling and this might explain why these patients experience this hyperexcitability.
#Spontaneous Rare Mutations Cause Half Of Autism Researchers are saying a new analysis of data on the genetics of autism spectrum disorder disputes a commonly held belief that autism results from the chance combinations
instead, further evidence to suggest that devastating"ultra-rare"mutations of genes that they classify as"vulnerable"play a causal role in roughly half of all autism spectrum disorder cases.
a Cold Spring Harbotr Laboratory assistant professor and on faculty at the New york Genome Center, finds that"autism genes"-i e.,
and give rise to autism, usually don't remain in the gene pool for more than one generation before they are,
This is because those born with severe autism rarely reproduce. The team's data helps the research community prioritize which genes with LGDS are most likely to play a causal role in ASD.
The team pares down a list of about 500 likely causal genes to slightly more than 200 best"candidate"autism genes.
Almost two thirds of the sites suggested that vaccines cause autism, and more than 40 percent claim theye responsible for rain injury The majority present information as scientific when it doesn actually qualify for that distinction.
#Missing piece surfaces in the puzzle of autism A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS/Aix-Marseille Université),
Understanding the mechanisms that underlie autism spectrum disorders (ASD), which affect 7. 6 million people according to the World health organization,
but a host of other illnesses, including autism and schizophrenia. Researchers can learn a lot by analyzing CNVS in bulk samples--from a tumor biopsy
in part because the underlying causes for different subtypes of autism are diverse and not well-understood. here is no better example than early language development,
professor of neurosciences and co-director of the Autism Center of Excellence at UC San diego. ome individuals are minimally verbal throughout life.
more individualized treatments, said co-author Karen Pierce, Phd, associate professor of neurosciences and co-director of the Autism Center of Excellence.
and underlie later good versus poor language outcome in autism. These findings said researchers, will open new avenues of progress towards identifying the causes and best treatment for these two very different types of autism. or the first time,
our study shows a strong relationship between irregularities in speech-activation in the language-critical superior temporal cortex and actual,
but not all, on the autism spectrum. t
#Graphics in reverse Most recent advances in artificial intelligence such as mobile apps that convert speech to text are the result of machine learning, in
Garner group has shown that these regions can be informative about diseases ranging from cancer to autism spectrum disorder.
and completed cutting-edge work in understanding the genetics of autism. Building on its strengths in biology
#Researchers find biomarker for autism that may aid diagnostics By identifying a key signaling defect within a specific membrane structure in all cells, University of California,
they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.
Dr. J. Jay Gargus, Ian Parker and colleagues at the UCI Center for Autism Research & Translation examined skin biopsies of patients with three very different genetic types
and possibly digestive and immune problems associated with autism. e believe this finding will be another arrow in the quiver for early and accurate diagnoses of autism spectrum disorders,
said Gargus, director of the Center for Autism Research & Translation and professor of pediatrics and physiology & biophysics. qually exciting,
Autism spectrum disorder is a range of complex neurodevelopmental disorders affecting 2 percent of U s. children.
To see if IP3R function is altered across the autism spectrum, clinical researchers at The Center for Autism & Neurodevelopmental Disorders
which is affiliated with the Center for Autism Research & Translation are currently expanding the study
In the area of drug discovery, scientists at the Center for Autism Research & Translation continue to probe the IP3R channel,
The brains of people who have autism show signs of hyperexcitability, which is seen also in epilepsy,
Cells from individuals who have depressed autism exhibit levels of calcium signaling and this might explain why these patients experience this hyperexcitability.
lack of link to autism New research finds no evidence that thimerosal-containing vaccines cause negative behaviors or result in neuropathology in infant primates,
the administration of vaccines to rhesus macaques did not result in neuropathological abnormalities or aberrant behaviors such as those often observed in autism.
Cellular analysis of the cerebellum, amygdala and hippocampus three brain regions known to be altered in autism was vaccinated similar in
#Tool enhances social inclusion for people with autism The University of Alicante has developed together with centres in the UK Spain
and Bulgaria a tool designed to assist people with autism spectrum disorders by adapting written documents into a format that is easier for them to read
Although in principle the tool has been designed for people with autism spectrum disorders who generally have difficulties in areas such as communication social interaction
and autism-spectrum disorder can have profound lifelong effects on learning and memory but relatively little is known about the molecular pathways affected by these diseases.
and his team used human fetal brain cells to study the molecular effects of reducing the activity of genes that are mutated in two distinct autism-spectrum disorders.
and Dr. Howard Shane who leads the Autism Language Program and the Center for Communication Enhancement at Boston Children Hospital.
After graduating from university with a degree in computer science Izak created an ipad app that was inspired by his younger brother Oriel who has autism.
That increasingly important as researchers begin to see connections between Phelan-Mcdermid, autism, and other conditions.
First Emotion-Reading Apps for Kids with Autism The first mobile apps that use emotion-reading software to help kids with autism are nearing release,
Though the early academic research focused on applications such as helping people with autism, so far the technology has been used commercially to help marketers understand
We started out with research on autism, and we went out and did this commercial stuff.
and apply it back to autism again. The advertising work helped make the software more accurate by rainingit
Among others, these include people with nonverbal autism, people with nonverbal learning disorders, people with ALS, people with Rett Syndrome,
and treatment of neurological diseases ranging from autism to Alzheimer's disease to multiple sclerosis.""Instead of asking,'How do we study the immune response of the brain?''
Alzheimer's, Autism, MS and Beyond The unexpected presence of the lymphatic vessels raises a tremendous number of questions that now need answers, both about the workings of the brain and the diseases that plague it.
And there's an enormous array of other neurological diseases, from autism to multiple sclerosis, that must be reconsidered in light of the presence of something science insisted did not exist t
#Miniature brain'organoids'offer model for autism Scientists have grown miniature brains out of stem cells from people with autism,
Previous studies have looked at the genomes of those with autism to identify the genes that might be responsible,
but 80 percent of autism cases have no clear genetic cause. This is the first study to use brain organoids to investigate the disorder
The researchers took skin cells from four adolescent males with autism and from their fathers who were unaffected by the disorder.
Despite the fact that autism is a complex collection of disorders, the researchers found several clear differences between the brain organoids from the autistic boys and those from their fathers.
'Professor Vaccarino is hopeful that this approach to studying autism, as well as other brain disorders, can offer new insights.'
'This study speaks to the importance of using human cells to bring a better understanding of the pathophysiology of autism and, with that, possibly better treatments. e
it is possible that these blood vessels could be related to a large number of neurological and developmental conditions from autism to attention deficit disorder (ADD TO multiple sclerosis.
For many indications, such as Alzheimer and autism, the need for new treatments is enormous, yet investment in these areas is declining due to recent high profile failures.
In the field of autism, stakeholders such as academic researchers, pharma companies, and patient advocacy groups are coming together to better understand the inner workings of the disease in hopes to increase the development and approval of effective therapeutics.
multi-year collaborative program to develop the infrastructure underpinning new treatments for autism. These are just two instances of industry coming together to achieve a mutually beneficial goal
such as mental disability, autism, and cancer. Sticky-flares have the potential to help scientists understand the complexities of RNA better than any analytical technique to date
Almost one-third of patients with fragile X also show symptoms of autism spectrum disorders.
#Scientists grow human mini-brains that are giving big insights into autism Scientists first grew mini-hearts in a lab. Then they 3d printed skin.
In a study published last week in Cell, a team from Yale School of medicine used the technique to glean insight into why autism occurs in some people without a clear genetic cause.
Within a month, it was apparent that organoids created from people with autism overproduced one type of neuron that acts to dampen the chatter of normal neural activity.
and may in part cause the faulty wiring behind autism behavioral symptoms. Further sleuthing led the scientists to a single gene responsible for the glitch.
Before mini-brains, scientists had to shift through gobs of genomic data to fish out gene variants associated with autism.
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