| Amnesia (8) |  |
| Anorexia (5) | |
| Anxiety (61) | |
| Ataxia (18) | |
| Autism (210) | |
| Delusional disorder (9) | |
| Dementia (87) | |
| Hallucination (11) | |
| Mania (51) | |
| Mental disorder (32) | |
| Multiple sclerosis (75) | |
| Paranoia (7) | |
| Phobia (5) | |
| Psychosis (9) | |
| Schizophrenia (137) | |
| Speech disorder (7) | |
| Stress (299) | |
#Problems With attention Traced to Specific Brain Circuit People with schizophrenia, for example, often find it difficult to focus their attention on a task or conversation.
The ability to do so lies at the heart of the attention problem in schizophrenia and other psychiatric disorders.
much like attention deficit in people with schizophrenia? was intriguing for several reasons. First, the Erbb4 receptor and the molecule known as neuregulin-1 that normally connects,
or ockswith it, have repeatedly been observed to be irregular in genetic studies of people with schizophrenia.
The team results are additional evidence that these proteins are regulated abnormally in schizophrenia. The experiments also explain what appears to go wrong
#The telltale blood of schizophrenics It can take a long time for schizophrenia sufferers to receive the treatment they need partly
The EU-funded Schizdx project has developed the world first blood test for schizophrenia. This breakthrough dramatically reduces the time needed to confirm suspected cases
or split personalities involved in schizophrenia. It is a disorder where the various mental functions gradually break down,
People developing symptoms of schizophrenia don usually attribute their altered sense of reality to an illness.
The Schizdx team conducted extensive research into the traces that schizophrenia and similar psychotic disorders leave in the body.
or doesn have schizophrenia, but to determine which, if any, of the three disorders the person does have.
and psychiatric diseases including bipolar disorder and schizophrenia. Four technical partners based in Archamps (FR), Paris (FR), Bristol (UK),
Researchersinterests in these networks have grown enormously over the past decade as the networks have been tied to many different aspects of brain health and sickness, such as schizophrenia, autism and Alzheimer disease.
the same technology framework developed for bipolar disorder could prove useful in everything from schizophrenia and posttraumatic stress disorder to Parkinson disease,
#Anticancer drug reverses schizophrenia symptoms in teen mice An experimental anticancer drug appears to reverse schizophrenia-related behavior
The compound, called FRAX486, appears to halt an out-of-control biological runingprocess in the schizophrenic brain that unnecessarily destroys important connections among brain cells,
Working with mice that mimic schizophrenia and related disorders, the researchers were able to partially restore disabled neurons
The findings in adolescent mice are an especially promising step in efforts to develop better therapies for schizophrenia in humans,
because schizophrenia symptoms typically appear in late adolescence and early adulthood. Schizophrenia is a chronic,
severe mental disorder that affects about one in 100 people, the National institute of mental health says. Patients may experience hallucinationsften hearing nonexistent voicesnd delusions
MISSING SPINES The researchers began their study by chemically turning down expression in their mice of a gene known as Disrupted-in-Schizophrenia 1. DISC1,
Sawa cautions that it has not yet been shown that PAK is elevated in the brains of people with schizophrenia.
In schizophrenia the first noise makes no impact on the reaction to the second one.
Grants from the National institutes of health, the Stanley Foundation, the RUSK Foundation, the S-R Foundation, the National Alliance for Research on Schizophrenia and Depression, Johns Hopkins Medicine Brain science Institute, the Maryland
#What causes schizophrenia?:Nature News Findings from a'brain training'study challenge theory. Researchers in Sweden have revealed a surprising change in brain biochemistry that occurs during the training of working memory,
The discovery may have implications for understanding disorders in which working memory is deficient such as schizophrenia and attention deficit hyperactivity disorder (ADHD.
"The density of neurotransmitter receptors is known to change in psychiatric disorders like schizophrenia, and this has been considered a cause of the diseases,
The biological causes of mental illnesses such as schizophrenia and bipolar disorder have mystified scientists for decades; in the last five years however understanding has accelerated dramatically driven by advances in human genomics.
Because researchers cannot study the biochemistry of the living human brain the genes that predispose people to schizophrenia
Since 2004 Ted Stanley and his late wife Vada Stanley have been instrumental to the progress made thus far in identifying the genetic risk factors for schizophrenia and bipolar disorder and the initiation of therapeutic efforts based on those discoveries.
Biomedical researchers have struggled for years to understand the molecular causes of serious ailments such as schizophrenia and bipolar disorder.
Yet in the past few years scientists have begun to find genes that shape the risk of schizophrenia bipolar disorder and other illnesses thanks in large part to Stanley s support.
and assembled the world s largest collection of DNA samples in psychiatric research currently more than 175000 samples including schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and healthy control samples.
Analysis of 80000 of these samples so far by Broad researchers and collaborators has linked more than 100 genomic regions to schizophrenia
Complete the list of all genes that play roles in severe psychiatric disorders including schizophrenia bipolar disorder autism and others.
Stanley Center researchers focus on schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and other neuropsychiatric disorders.
#Schizophrenia linked to abnormal brain waves Schizophrenia patients usually suffer from a breakdown of organized thought often accompanied by delusions or hallucinations.
Mutations in the gene for calcineurin have previously been found in some schizophrenia patients. Ten years ago MIT researchers led by Susumu Tonegawa the Picower Professor of Biology
these mice displayed several behavioral symptoms of schizophrenia including impaired short-term memory attention deficits and abnormal social behavior.
This pattern helps to explain some of the symptoms seen in schizophrenia the researchers say.
However this network is hyperactive in schizophrenic patients before and during tasks that require the brain to focus
Further studies of these mice could help reveal more about the role of the default mode network in schizophrenia Tonegawa says.
Zhang plans to use the techniques to study the genetics of autism and schizophrenia. He has begun already to insert genes linked to each disorder one by one into animal models to observe their effects.
Many mental disorders, including depression, schizophrenia and anxiety, affect neurotransmitter systems,"said Axel Brunger, the study's principal investigator.
Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia,
#Brain training app that could help schizophrenia sufferers live a normal life A new brain training app developed to help improve the memory of people with schizophrenia could save taxpayers thousands of pounds,
which found that schizophrenia patients who played the game regularly for a month were four times better at remembering these kinds of things than non-players.
Schizophrenia is estimated to cost £13. 1billion per year in total in the UK. The long-term mental health condition can cause a range of symptoms including hallucinations and delusions.
and is aimed at people who suffer with poor episodic memory-one of the main side effects of schizophrenia drugs.
who had been given a diagnosis of schizophrenia, to either the cognitive training group or a control group at random.
which scientists say is important as lack of motivation is another common aspect of schizophrenia.
'We need a way of treating the cognitive symptoms of schizophrenia, such as problems with episodic memory,
this could help people with schizophrenia minimise the impact of their illness on everyday life.'
They hope the discovery may help the search for treatments for disorders such as Alzheimer's, schizophrenia and post traumatic stress disorder (PTSD.
#Our osetta Stonegene Could Unlock The Secrets Of Schizophrenia Schizophrenia affects around 1%of the global population
when treatments may be most effective in preventing schizophrenia manifesting in the first place. Mental health conditions are among the most challenging medical problems we face as scientists,
But despite knowing about hundreds of mutations associated with schizophrenia, we are relatively in the dark about
One gene we do have some certainty about is known as isrupted in schizophrenia gene 1 (DISC1.
when mutated, can give rise to a number of mental health conditions including schizophrenia, bipolar disorder, major clinical depression and autism.
While schizophrenia may be inherited, the probability of inheritance from a mutation carried by one parent alone is relatively low.
Targeting Schizophrenia Vulnerable Period Different parts of the brain may mature at different times but most cortical areas go through a similar sequence of development.
So how can studying DISC1 help us decode what is going wrong with other genes in schizophrenia?
or at least many of the genes identified as risk factors in schizophrenia. DISC1 mutations have also been linked to autism
what the other genes involved in schizophrenia are doing (or doing wrong) during development to give rise to the debilitating condition of schizophrenia o
#Scientists Control Brain cells Using Sound waves The ability to control brain cells with sound waves sounds like science fiction, right?
#'Brain training'game helps people with schizophrenia live a normal life Patients who played the game regularly for a month were four times better than non-players at remembering the kind of things that are critical for normal, day-to-day life,
People recovering from schizophrenia suffer serious lapses in episodic memory which prevent them from returning to work
Schizophrenia affects about one in every hundred people and results in hallucinations and delusions (Rex) his kind of memory is essential for everyday learning
Schizophrenia affects about one in every hundred people and results in hallucinations and delusions it is estimated to cost the NHS about £2bn a year in treatment alone,
which has led scientists to find ways of training the brain through computer-based games. e need a way of treating the cognitive symptoms of schizophrenia, such as problems with episodic memory,
The study, published in the Philosophical Transactions of the Royal Society B, involved 22 schizophrenia patients who played the game for eight hours over a period of four weeks
Importantly, the patients with schizophrenia enjoyed playing the game and were motivated to continue. The group that played the game was approximately four times better in terms of their memory than the group that did not,
this could help people with schizophrenia minimise the impact of their illness on everyday life. i
but brain disorders like schizophrenia, and degenerative brain disease. ACES Director and research author Professor Gordon Wallace said that the breakthrough is significant progress in the quest to create a bench-top brain that will enable important insights into brain function,
About one out of every hundred Norwegians develop schizophrenia or autism in the course of their lifetime.
Many psychiatric disorders such as autism, schizophrenia and bipolar disorder are characterised by poor social functioning. Oxytocin is a hormone that influences social behaviour
#Brain training app could help people with schizophrenia Scientists at Cambridge university said tests on a small number of patients who played the game over four weeks found they had improvements in memory and learning.
Schizophrenia is a long-term mental health condition that causes a range of psychological symptoms, ranging from changes in behavior through to hallucinations and delusions.
There is increasing evidence that computer-assisted training can help people with schizophrenia overcome some of their symptoms, with better outcomes in their daily lives.
since lack of motivation is a common feature of schizophrenia.""We need a way of treating the cognitive symptoms of schizophrenia, such as problems with episodic memory,
but slow progress is being made toward developing a drug treatment, "said Barbara Sahakian from the department of psychiatry at Cambridge university."
or dysfunction including cerebral palsy, age-related dementia, optic neuritis and schizophrenia. Any drugs developed that enhance myelination in multiple sclerosis also hold promise for benefiting these other disorders."
and effect might lie at the heart of some psychiatric disorders that involve delusional thinking, such as schizophrenia."
but brain disorders like schizophrenia, and degenerative brain disease. Researchers have completed now 3-D printing a six-layered structure similar to brain tissue, in
but brain disorders like schizophrenia, and degenerative brain disease. ACES Director and research author Professor Gordon Wallace said that the breakthrough is significant progress in the quest to create a bench-top brain that will enable important insights into brain function,
Many mental disorders, including depression, schizophrenia and anxiety, affect neurotransmitter systems,"said Axel Brunger, the study's principal investigator.
but a host of other illnesses, including autism and schizophrenia. Researchers can learn a lot by analyzing CNVS in bulk samples--from a tumor biopsy
and may lead to new treatments that involve BNIP-H."Our findings could provide new direction to better understand causes of cholinergic-related diseases, such as Alzheimer's disease, Down's syndrome, ataxia and schizophrenia.
and may lead to new treatments that involve BNIP-H."Our findings could provide new direction to better understand causes of cholinergic-related diseases, such as Alzheimer's disease, Down's syndrome, ataxia and schizophrenia.
#Brain-training game helps'minimise impact of schizophrenia on life'A rain traininggame improves the cognitive function of people with schizophrenia
was tested for four weeks by 22 participants with a schizophrenia diagnosis. Schizophrenia is a long-term mental health condition
People with schizophrenia may experience cognitive impairments, including poor episodic memory, which affects remembering things such as times and dates,
Wizard aims to improve the cognitive functionality and episodic memory of people with schizophrenia, with in-game tasks including users moving through rooms and identifying items in boxes and character locations.
e need a way of treating the cognitive symptoms of schizophrenia, such as problems with episodic memory,
n conjunction with medication and current psychological therapies, Wizard could help people with schizophrenia minimise the impact of their illness on everyday life. eople with schizophrenia often find studying
The employment rate for people with schizophrenia was recorded at 8%,according to a 2013 paper. The Wizard game will be included as a mode within the popular brain-training app, Peak,
#More than A hundred Genetic Variants Tied to Schizophrenia To a large extent, schizophrenia and other psychiatric disorders are caused illnesses by genes.
Now teams of scientists from research centers around the world, looking at the genetics of nearly 80,000 people, have worked together to identify 108 genetic loci associated with the disorder.
including schizophrenia. The lack of such understanding to date has meant there hasn been a true new breakthrough drug to treat these disorders in 50 years.
and someone with schizophrenia would be a leap in our understanding of how our brains shape who we are (or vice versa).
and the National Alliance for Research on Schizophrenia and Depression provided funding for the study.
and someone with schizophrenia would be a leap in our understanding of how our brains shape who we are (or vice versa).
SCHIZOPHRENIA BIPOLAR OR MANIACO-DEPRESSION, HOW PLASMA PROTEINS PRODUCE THE CONDITION AT THE BRAIN CELLS'LEVEL OF CHEMICAL IMBALANCE,
#Disruption of Delicate Chemical Balance Implicated as a Cause of Schizophrenia Scientists produce strongest evidence yet of schizophrenia causes.
what causes schizophrenia a condition that affects around 1%of the global population. Published today in the journal Neuron,
published last year in the journal Nature. ee finally starting to understand what goes wrong in schizophrenia,
and Genomics. ur study marks a significant step towards understanding the biology underpinning schizophrenia, which is an incredibly complex condition
his work builds on our understanding of the genetic causes of schizophrenia unravelling how a combination of genetic faults can disrupt the chemical balance of the brain. cientists in the UK,
as part of an international consortium, are uncovering the genetic causes of a range of mental health issues, such as schizophrenia. n the future,
this work could lead to new ways of predicting an individual risk of developing schizophrenia
Researchers studying psychiatric disorders have suspected previously that disruption of this balance contributes to schizophrenia. The first evidence that schizophrenia mutations interfere with excitatory signalling was uncovered in 2011 by the same team,
based at Cardiff University MRC Centre for Neuropsychiatric Genetics and Genomics. This paper not only confirms their previous findings,
To reach their conclusions scientists compared the genetic data of 11,355 patients with schizophrenia against a control group of 16,416 people without the condition.
Comparing the CNVS found in people with schizophrenia to those found in unaffected people the team was able to show that the mutations in individuals with the disorder tended to disrupt genes involved in specific aspects of brain function.
Around 635,000 people in the UK will at some stage in their lives be affected by schizophrenia.
The estimated cost of schizophrenia and psychosis to society is around £11. 8 billion a year.
The symptoms of schizophrenia can be extremely disruptive, and have a large impact on a person ability to carry out everyday tasks,
and schizophrenia resist complete reprogramming. A team of researchers led by the University of Cambridge has described for the first time in humans how the epigenome the suite of molecules attached to our DNA that switch our genes on
and schizophrenia resist complete reprogramming. Although our genetic information the ode of lifeis written in our DNA,
However, data analysis of human diseases suggests that such genes are associated with conditions such as schizophrenia, metabolic disorders and obesity.
this knowledge can be helpful in the development of therapeutic interventions for neurological diseases underlined by altered dendritic spine density, such as autism spectrum disorder, Schizophrenia or Alzheimer's disease.
and to understanding the basis of neurodevelopmental and neurodegenerative disorders such as schizophrenia Alzheimer's disease and epilepsy.
of which has previously been implicated in risk for schizophrenia. The article published in Nature today is'Common genetic variants influence human subcortical brain structures
Mesencephalic dopaminergic (mda) neurons and their connections to other neurons in the brain are believed to be related to disorders including drug abuse, schizophrenia, Parkinson's disease,
Abnormal immune activity was reported in schizophrenia in the 1930s, and numerous mental and neurologic illnesses are known
including autism and schizophrenia. With these new findings, e now have an opportunity to investigate how gene mutations that cause
Mesencephalic dopaminergic (mda) neurons and their connections to other neurons in the brain are believed to be related to disorders including drug abuse, schizophrenia, Parkinson disease,
and someone with schizophrenia would be a leap in our understanding of how our brains shape who we are (or vice versa).
like schizophrenia or Parkinson disease (see racking the Brain Codesand hining a Light on Madness.
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