Genetics

Genetic alteration (8)
Genetic experiments (5)
Genetic improvement (5)
Genetic information (83)
Genetic manipulation (9)
Genetic marker (9)
Genetic testing (26)
Genetic variation (35)
Genetically modified organism (16)
Genetics (251)

Synopsis: Biotech: Genetics: Genetics:

"Assessments of patients based upon the latest diagnostic criteria may boost the field's chances of finding new genetic markers for PTSD,

This capability is a significant advance for genetics research and provides a new way to study both the normal brain and brain disorders such as epilepsy and autism.

"says Christopher Walsh, MD, Phd, chief of Genetics and Genomics at Boston Children's and co-senior author on the paper."

#Biogen idec Columbia to Conduct Collaborative Genetics Research Biogen idec and Columbia University Medical center have formed a $30 million strategic alliance to conduct genetics discovery research on the underlying causes of disease

and analysis facility and shared postdoctoral program will be established at Columbia to support collaborative genetics studies.

Biogen idec. e are committed to working with leading institutions such as Columbia to advance basic genetic research and,

The new facility will have broad genetic research capabilities and the capacity to launch and complete whole-genome sequencing projects rapidly.

We expect that the alliance will dramatically advance our understanding of the genetics of these devastating diseases and ultimately lead to mechanism-based treatments, a key aspect of Columbia precision-medicine initiative. c

and less than 1%get genetic testing. Familial DCM is enetically heterogeneous says Arbustini. That means several different genes may cause the disease.

#Massive study closes in on cancers risk markers Cancer research has taken a huge leap forward with scientists now able to identify more than 80 genetic markers found to increase the risk of breast ovarian and prostate cancer.

for cancer in the prestigious scientific journal Nature Genetics. The research was led by scientists at the Karolinska Institutet in Sweden, the University of Cambridge and the Institute of Cancer Research (ICR) in the UK,

Overall, the study found that common genetic variation links all these cancers. This can be described as a genetic'spelling mistake'

We're on the verge of being able to use our knowledge of these genetic variations to develop a test that could complement breast cancer screening

Bringing together biologists, chemists, microbiologists, biochemists, molecular geneticists and biotechnologists from universities, biotech firms and food and pharmaceutical multinationals from around Europe, Polymode has identified now its first eadingand ritingenzymes.

and the functioning of a living organism), was the only carrier of genetic information. Everything else was merely a product of these genes."

whether this genetic information was just redundant, or whether it could be used to trigger the production of new antibiotic compounds.'

Researchers analyzed the sustainability of the US dairy industry from 1944 to 2012 and found advances in genetics

and if some are susceptible could they harness the power of mouse genetics to figure out what genes make someone susceptible to the disease.

when infected with the virus. The team was able to show that a combination of genes were involved in producing a range of disease symptoms such that the genetic variation of the mice directly led to the variety of symptoms that the disease produced.

##A basic understanding of how our genetics influence susceptibility to viral infections and affect disease development is absolutely critical to creating much needed therapeutic interventions.##

and a research assistant professor of genetics in the UNC School of medicine says:####Public perception of Ebola infection typically focuses on the high mortality rate following hemorrhagic fever

##During an outbreak it is often difficult to assess the role that genetic variation plays in determining disease severity in people.

And if we re going to develop treatments then we need to know about this genetic variation.##

The discovery of a aternal age effectfor mitochondrial diseases could be a valuable tool for genetic counseling, report researchers.

infect cells by ejecting their genetic information into a host cell. But how does the usually rigid DNA packaged inside a virus shell flow from the virus to the cell?

and will soon be available through the Veterinary Genetics Laboratory at the UC Davis School of veterinary medicine.

The microbe contains interesting genetic sequences, but it has proven challenging to culture in the lab. Researchers used the device, called Slipchip,

He and his colleagues began by looking for bacterial species that contained a set of specific genetic sequences.

The microbes carrying these genetic sequences are found abundantly in and on the human body, but have been difficult to grow in the lab. To grow these elusive microbes,

and linking the data to the residential addresses of approximately 1000 participants in the Northern California-based Childhood Risk of Autism from Genetics and the Environment (CHARGE) Study.

The results appear in PLOS Genetics. It is possible that low-nutrient diets set off the same pathways in us to put our cells in a quiescent state says David R. Sherwood an associate professor of biology at Duke university.

People in a given geographical area are more likely to have similar genetics. When they also have genetic traits typically found in other, distant regions,

The findings appear online this week in the journal PLOS Genetics. his discovery provides novel insight into the genetic cause of a form of cleft palate through the use of a less conventional animal model says study leader Professor Danika Bannasch,

a veterinary geneticist at the UC Davis School of veterinary medicine. t also demonstrates that dogs have multiple genetic causes of cleft palate that we anticipate will aid in the identification of additional candidate genes relevant to human cleft palate.

and a senior co-author of the study published in Nature Genetics. ince this gene has previously been identified as a target for the development of new drugs, in the future,

associate researcher in genetics at Yale university and co-lead author of the study. Researchers were interested in using mice without the FAT10 gene to study its role in sepsis

which vary in genetic sequence, exhibit different properties that can be used to, for example, distinguish them from each other in an ultrasound image.

For example if we want to understand the genetics of how silk is produced we must first understand how silk worms evolved over time

since accurate measures of organismal relationships are fundamental to our interpretation of morphology genetics and physiology to name a few. ust as the diversity of insects has always been a problem for scientists the project s goal of analyzing a large number of insect transcriptomes posed a major challenge

questionssays Eric Lyons assistant professor in the School of Plant Sciences at University of Arizona. ow does stored the genetic information in the genome help us understand the functions of the organism

and the underlying genetic mechanism. he parasitic ants need to exercise discretion because taking advantage of the host species is considered taboo in ant society.

Now detailed reanalysis by an international team of researchers including Robert B. Eckhardt professor of developmental genetics

and genetics research of insects Kawahara says. here is a DNA revolution taking place. This is an important time in the history of science

what geneticists call physical maps a tool that enables scientists to understand the structure of the genome.

and Asian rice. y understanding the entire genus at a genome level we have a whole new pool of genetic variation that can be used to combat pests

But now findings published in the journal PLOS ONE suggest that the solution may lie not with genetics alone but rather with a combination of genetic and epigenetic factors.

When crops are optimized with the right genetics and colonized by the right microbes both organisms can flourish.

of molecular biology and genetics at Cornell University. Using mouse studies only about 100 genes with imprinted expression had been identified.

what breeders call the maternal grandsire effect says co-senior author Doug Antczak equine geneticist at Cornell s College of Veterinary medicine.

Their findings appear in Theoretical and Applied Genetics. It was a surprise that we could trace the gene back so far

since 1999 threatening important wheat production areas of the world#says co-author Jorge Dubcovsky a wheat geneticist at University of California Davis and a Howard Hughes Medical Institute investigator.#

We ve shown that this first component the genetics involves not just one gene mutation but several that need to coexist before evolution can happen.

whereby a small number of skilled geneticists is able to remove the nucleus of a donor woman egg (the part that plays host to some 25,

the geneticist who pioneered the technique, told me from his office at Oregon Health and Sciences University just outside Portland. his procedure uses a very high-tech imaging system microscopes, lasers,

and a growing number of geneticists is now exploring the role of misbehaving mitochondria in basic aging.)

Dr. Marcy Darnovsky, executive director of the California-based Center for Genetics and Society, in an open letter. nder the proposed arrangement,

#Ana Gomes#at Harvard Medical school and her colleagues compared the levels of MESSENGER RNA (mrna) molecules that convey genetic information around a cell for the cellular components needed for respiration in the skeletal muscle of 6 and 22-month-old mice.

Scientists expect the project to be pivotal to the development of future personalised treatments based on genetics, with the potential to revolutionise medicine.

However successful crop genetics might be new plant varieties cannot compensate for the deficiencies in systems.

Within these exosomes is genetic information that can be analyzed to determine the cancer s molecular composition and state of progression.

Researchers at Massachusetts General Hospital discovered that exosomes preserve the genetic information of their parent cells in 2008

The government has supported also work on the genetics of both the fungus and the plant. Research programmes have started in other countries, too.

says George Church a molecular geneticist at Harvard Medical school in Boston, Massachusetts, who encoded a draft of his latest book in DNA last year2."

April 2009 Paper reports successful derivation of human ips cells without the integration of genetic information into the cell genome.

says Mark Stoneking, a geneticist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany,

Irina Pugach, a postdoctoral researcher in Stoneking s laboratory, discovered signs of the Indian migration by comparing genetic variation across the entire genomes of 344 individuals, including Aboriginal australians from the Northern territory, highlanders

Sheila van Holst Pellekaan, a geneticist at the University of New south wales, Australia, and a co-author of the earlier genome-wide study,

a geneticist at the University of Copenhagen who last year showed3 that leeches can also preserve the DNA of the animals they feed on.

#Circular RNAS throw genetics for a loop Behold the latest curio in the cabinet of RNA oddities:

So Jalas, the centre s director of genetics resources and services, has outsourced parts of the analysis. He uploads his clients sequencing data to cloud-computing software platforms

Jalas and the way he works represent a new and mostly untapped market for a new crop of genetics interpretation and analysis firms,

which will be touting for customers at a meeting of the American College of Medical Genetics and Genomics in Phoenix, Arizona, on 19-23 march.

and clinical geneticists may be uneasy about uploading data to the cloud.""It s your licence and your lab that go on the line

#Wildlife trade meeting endorses DNA TESTING of seized ivory If you go into a bar in Bangkok tonight,

because it was the first time that the entire COP acknowledged the value and need for DNA TESTING for the origin of poached ivory.

said study co-leader David B. Goldstein, Phd, professor of genetics and development and director of the new Institute for Genomic Medicine at CUMC.

principal investigator of the Alzheimer Disease Genetics Consortium and a study co-author. n important aspect was the collaborative nature of this work.

Thanks to our collaborators from the Consortium, the International Parkinson Disease Genetics Consortium, the Genetic and Environmental Risk in Alzheimer Disease, the Cohorts for Heart and Aging research in Genomic Epidemiology, decode Genetics and the Demgene cohort,

The recent association of genetic variation in the MAPT gene with AD risk and the emerging availability of tau imaging are now leading to a recognition that perhaps tau changes are key in the pathophysiologic pathway of AD

About this genetics research Other authors of the report include Kalyan Kondapalli, Jose Llongueras, Vivian Capilla-Gonzalez, Hari Prasad, Anniesha Hack, Christopher Smith and Hugo Guerrero

a professor of genetics at Harvard Medical school who was not part of the research team. MIT researchers led by Ed Boyden have invented a new way to visualize the nanoscale structure of the brain and other tissues.

One important piece of evidence will be the genetic sequence of the virus. Ben Embarek says Korea has agreed to share samples with several labs working on MERS,

A team of bioengineers and geneticists has designed a device that can suspend a single living cell between magnets and measure its density based on how high it floats.

Immunologists geneticists and genomics researchers drive Progress to this wealth of information clinicians contribute patient-based insights and gain potential targets for therapeutics.

and Neuroscience director of the RIKEN-MIT Center for Neural Circuit Genetics at MIT s Picower Institute for Learning and Memory and senior author of the paper.#

#An easier way to manipulate malaria genes Plasmodium falciparum the parasite that causes malaria has proven notoriously resistant to scientists efforts to study its genetics.

which P. falciparum genetics have been done in the past even 50 percent is pretty substantial. For both targets the researchers demonstrated that they could insert a gene for the protein luciferase

because we ve struggled with the technical aspects of doing these genetic experiments says Kirk Deitsch a professor of microbiology

If you want to get at the molecular pathogenesis of these disorders you ve got to crack the genetics.

and Lander served as a member of the NIMH s Genetics Workgroup; the three had developed a mutual respect and a shared vision for

and genetics and along with Scolnick and Lander supported the collection of DNA samples from patients with the hope that the samples could someday be analyzed to find disease genes.

To create a comprehensive catalog of the genetic variation that underlies mental illness the researchers plan to expand their international network

and animal models that more faithfully match both the genetic variation and the biochemical processes seen in human patients.

We re still at the beginning of the curve of translating the emerging genetics into actionable biology but it s happening much faster than

Genetic information is carried normally from DNA in the nucleus to ribosomes, cellular structures where proteins are made.

Short strands of RNA called sirna bind to the MESSENGER RNA that carries this genetic information preventing it from reaching the ribosome.

says Constance Cepko, a professor of genetics at Harvard Medical school. Previous efforts have focused on analyzing only a small number of cell types at a time,

and genetics at Rockefeller University who was not part of the research team. Using these mice the researchers found that before treatment tumors lacking both MK2

and colleagues at the RIKEN-MIT Center for Neural Circuit Genetics at MIT s Picower Institute for Learning and Memory recorded the electrical activity of individual neurons in the hippocampus of these knockout mice

#Patent awarded for genetics-based nanotechnology against mosquitoes insect pests Kansas State university researchers have developed a patented method of keeping mosquitoes and other insect pests at bay.

The patent covers microscopic genetics-based technology that can help safely kill mosquitos and other insect pests.

MESSENGER RNA carries important genetic information. In the studies on mosquito larvae researchers designed dsrna to target the mrna encoding the enzymes that help mosquitoes produce chitin the main component in the hard exoskeleton of insects crustaceans and arachnids.

#Gold nanoparticles linked to single stranded-dna DNA create a simple but versatile genetic testing kit Tests for identifying genetic variations among individuals

Ying's method detects genetic variations known as single-nucleotide polymorphisms (SNPS) that differ in only a single-nucleotide building block of DNA.

Nanoprobe-based genetic testing. Nano Today 9 166#171 (2014. dx. doi. org/10.1016/j. nantod. 2014.04.00

In cells, nanomachines such as ribosomes and DNA polymerases stitch individual molecules together to form complex biological structures such as proteins and DNA molecules, the repositories of genetic information.

Like the molecule that carries genetic information in living things, the synthetic DNA strands used as"glue"to bind nanoparticles in this study have a natural tendency to pair up

Genetic testing can improve the treatment of such medical conditions. By combining our expertise in molecular diagnostics and nanotechnology,

IBN's test kit can recognize three of the most common genetic variations, or single-nucleotide polymorphisms, associated with warfarin response.

If any of the three genetic variations is present the solution will remain pink. But if none of the variations is present,

and can be extended to detect other genetic variations. By making molecular diagnostics information more readily available, doctors will be able to provide personalized treatment that is safer and more effective

and the DNA double helix has been the key to understanding how genetic information is stored and passed on.

and suppress the use of genetic information stored in their DNA A

#MEMS nanoinjector for genetic modification of cells The ability to transfer a gene or DNA sequence from one animal into the genome of another plays a critical role in a wide range of medical researchncluding cancer, Alzheimer's disease, and diabetes.

Not all parts of the body age alike according to Steve Horvath a geneticist at UCLA's medical school.

They dramatically sped up the study of genetics and disease. The techniques Zhang helped develop called TALE

and CRISPR create transgenic or otherwise genetically modified organisms with unprecedented efficiency. TALE is a molecule that gloms onto a section of DNA

Zhang plans to use the techniques to study the genetics of autism and schizophrenia. He has begun already to insert genes linked to each disorder one by one into animal models to observe their effects.

which carry genetic information from DNA reveal which genes are turned on and how often they're active.

#DNA TESTING chip delivers results in one hour, paves way for personalized drug treatments Panasonic, together with the Belgium-based research institution IMEC, has developed a DNA TESTING chip that automates all stages of obtaining genetic information,

including preprocessing. This development is expected to enable personalized, tailor-made therapy to become widespread. his is the chip wee actually developed.

#Desktop PC-sized fully automatic genetic testing device The Genelead from Precision System Science (PSS) is a fully automatic genetic testing device that completely automates the genetic testing process that ordinarily would require manual intervention.

At this time genetic testing is conducted typically only at large research facilities but PSS aims to create an environment where genetic testing devices can be used at more medium-sized hospitals emergency testing hospitals and even small clinics.

Under the concepts of companion diagnostics and personalized medicine that have recently become popular topics in the US as well as Japan the idea is to use medicine suited to the patient and conduct genetic testing for that purpose.

As these types of devices become widespread even the town doctor will be able to conduct these tests.

and genetic manipulation, described this week in the journal Nature Materials, was the work of MIT professors Angela Belcher,

professor of genetics at Harvard university and an author on the paper published this week in Science Express.

and the correct sequence of our genetic information is vital to the accurate transmission of our genetic code.

that threaten the fidelity of our genetic information. The accurate processing of these roadblocks is paramount to genome integrity.

or loss of genetic information that in turn can cause premature aging, cancer, and genetic abnormalities. Depending on the degree of genome instability

Crop breeding programmes can make use of this genetic information to ensure that the preferred trait is inherited by future crop yields,

whether or not an individual organism has associated the genetic variation with a given trait. As an open access tool, researchers and crop breeders can submit their own data to Polymarker

and the online tool will return suggested design primers to identify genetic variations that tag vital traits in their crop samples,

and applied in a research project where it identified genetic markers that signal resistance to the wheat yellow rust pathogen (Puccinia striiformis f. sp. tritici).

In one new software tool, we have applied expertise in advanced algorithm development, knowledge on genetics and principles of genome architecture."

A processor from the company Edico Genome that designed to handle the big data of genetics.

Most tech innovation in agriculture was concentrated narrowly in biotechnology and seed genetics, and both investment and innovation was limited to players with close ties to the ag sector.

Outside of seed genetics and crop inputs, most other Agtech was bundled typically with Cleantech. Then, in 2013, there was a shift.

"Our findings provide a genetic marker that could be used to identify those RA patients who require more aggressive treatments

Genetics was still developing and the scientists thought no more of this. Sometime later it was found that these CRISPR sequences were used by bacteria to ward off predatory viruses. The mechanism was unravelled

transmit and express genetic information. Scientists are currently investigating ways of using nucleic acids to reprogram cells to carry out different functions.

Even though all the cells in our body have the same genetic information, they are not expressing all the genes at the same time.

"and are strung together in various combinations that contain the cell's genetic information, such as genes. Essentially

. who is a pioneer in the converging fields of synthetic biology, metabolic engineering, and genetics. Church is the Robert Winthrop Professor of Genetics at Harvard Medical school and Professor of Health Sciences and Technology at Harvard and MIT.

Critical to this process of metabolically engineering microbes is the use of biosensors. Made of a biological component-such as a fluorescent protein

"Because the good genetic variation we introduced already exists in nature, this approach should be effective and safe.

Church is Core Faculty member at Harvard's Wyss Institute for Biologically Inspired Engineering, Robert Winthrop Professor of Genetics at Harvard Medical school and Professor of Health Sciences and Technology at Harvard and MIT,

Because the laboratory identified the genetic sequences that encode this behavior they were able to point out a long list of human proteins that likely exhibit it. his paper shows the incredible richness of peptide sequences that already have this very simple switch,

A team from Oxford university's Department of Physiology, Anatomy and Genetics led by Dr. Deborah Goberdhan worked with cancer doctor and researcher, Professor Adrian Harris,

said study author Rusty Gage, a professor in the Salk Institute Laboratory of Genetics. Researchers believe this technique will be very helpful to scientists studying age-related diseases

"said first author Mackenzie Lind, a doctoral candidate at the Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University in Richmond."

and we turn off the genetic information and the demographic and clinical information, and we see that with combined information,

This included data on genetic markers known as single-nucleotide polymorphisms; demographic data, such as subject age, gender, marital status, and education level;

and say that the original motivation was curiosity about how much of anatomy we could predict from genetics

the gene-editing tool known as Crispr is on the brink of revolutionizing the field of genetics internationally.

#Gluten-free wheat quest undertaken by farmers Kansas farmers are paying for genetic research to figure out exactly why some people struggle to digest wheat.

The geneticists have applied for a unique licence from the Government fertility watchdog to carry out the procedure using a gene manipulation technique called Crispr/Cas9.

However most geneticists believe the procedure is not ready to be carried out on human embryos-after the Chinese research led to unwanted mutations in DNA.

She emphasised that there would be o GM babiesbecause the team simply wants to understand the genetics of early embryonic development.

In 2008 the UK laws on IVF was changed to allow genetic manipulation of embryos that are less than two weeks old for research purposes,

they created an easy way to tweak the genetic information in a cell nucleus. This has implications for medicine and agriculture.

but by searching a published database of bacterial genetic sequences for promising-looking bits of DNA. This yielded two species that contain the new mechanism.

who also is an investigator in the Center for the Genetics of Host Defense and holder of the George L. Macgregor Distinguished Chair in Biomedical science.

or byproducts,"says senior author Inder Verma, professor of genetics and holder of Salk's Irwin and Joan Jacobs Chair in Exemplary Life science."

From the Cancer Genome Atlas data, the Salk team found that genetic alterations of Epha2 were detected in 54 out of 230 patients with adenocarcinoma.

In research that appeared today in Nature Genetics, a Weizmann Institute of Science team has revealed now one of the drivers of a particularly deadly subset of melanomas-one that is still seeing a rise in new cases.

"said senior author Erez Lieberman Aiden, a geneticist and computer scientist with joint appointments at Baylor and Rice."

"Aiden, assistant professor of genetics at Baylor and of computer science and computational and applied mathematics at Rice, said Sanborn

genetics and disease diagnosis. But carrying out such analyses requires expensive lab equipment, making its application out of reach for many people who live in resource-limited places.

Professor Peter Waterhouse, a plant geneticist at QUT, discovered the gene in the ancient Australian native tobacco plant Nicotiana benthamiana, known as Pitjuri to indigenous Aboriginals tribes.

which for decades has been used by geneticists as a model plant upon which to test viruses and vaccines.

which for decades has been used by geneticists as a model plant upon which to test viruses and vaccines."

"Professor Waterhouse, a molecular geneticist with QUT's Centre for Tropical Crops and Biocommodities, said scientists could use this discovery to investigate other niche

Professor Waterhouse said the team's findings also have implications for future genetic research back here On earth."

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